SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO12103
Pre Gene Modal
BGIBMGA004269
Annotation
G_protein_alpha_S_subunit_Gs2_[Bombyx_mori]
Full name
Guanine nucleotide-binding protein G(s) subunit alpha       + More
G protein alpha s subunit      
Alternative Name
Adenylate cyclase-stimulating G alpha protein
Guanine nucleotide-binding protein G(s) subunit alpha
Location in the cell
Nuclear   Reliability : 2.601
 

Sequence

CDS
ATGCGCATCCTGCACGTCAACGGCTTCTCCGACAAGGAGCGCAAGGAGAAGATCGAGGACATCAAGAAGAACGTTCGAGATGCCATCATTACGATCACCGGTGCCATGAGTACCTTAACACCTCCGATTCCTCTCGAGAAACCGGAGAATAAACCACGCGTGGATTACATTCAGGACGTGGCGTCGCAGCCGGACTTCGACTACCCTTCGGAGTTCTACGAGCACACGGAGGCGCTGTGGAAGGACCAGGGCGTGCAGCGCACCTACGAGCGCAGCAACGAGTACCAGCTCATCGACAGTGCCAAATACTTCCTGGACAAGATCCACGTGATCAGACAGCCGGGCTACACGCCCACCGAGCAGGACGTCCTCCGCTGCCGGGTCCTCACATCCGGAATCTACCAGACGCAGTTCGTCGTGGACAAAGTTCACTTCCATATATTCGATGTCGGCGGACAACGCGACGAAAGACGCAAATGGATCCAGTGCTTCAACGATGTTACCGCGATCATCTTCGTGGCGGCCTGCTCCGCCTACAACATGGTGCTGCGCGAGGACCCCACGCAGAACCGGCTGCGCGAGTCCCTGGATCTGTTCAAGAGCATCTGGAACAACCGGTGGCTGCGGACCATCTCCGTCATCCTGTTCCTCAACAAGCAGGACCTGCTCGCCGAGAAGGTGCTGGCGGGGAAGTCTCGGCTCGAGGACTACTTCCACGAGTTCGCCCAGTACCAGACCCCGACTGACATGAAGCCAGACCCCAAAGATCACCCTGAAGTGACCCGCGCCAAGTTCTTCATTCGTGAGGAGTTTCTGCGCATCAGCACCGCCACGGGCGACGGCAAGCACGACTGCTACGCTCACTTCACGTGCGCCGTCGACACCGACAACATCCAACGAGTGTTCAACGGCTGCCGGAACATCATCCAGCGAGCTAACCAATGTGATTGCATTTACGTCTGTTTCGAACCGTCCACAGCAAAAACACAAACGGACAGACAAACCAACAGACACGACACGGACATAGCTTCGCTCGCGACCTCCCTGCCCTTTGTTAACCATGAAAATACAACGTCGAATTTGACGATGTTTTGGAGTTAG
Protein
MRILHVNGFSDKERKEKIEDIKKNVRDAIITITGAMSTLTPPIPLEKPENKPRVDYIQDVASQPDFDYPSEFYEHTEALWKDQGVQRTYERSNEYQLIDSAKYFLDKIHVIRQPGYTPTEQDVLRCRVLTSGIYQTQFVVDKVHFHIFDVGGQRDERRKWIQCFNDVTAIIFVAACSAYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSRLEDYFHEFAQYQTPTDMKPDPKDHPEVTRAKFFIREEFLRISTATGDGKHDCYAHFTCAVDTDNIQRVFNGCRNIIQRANQCDCIYVCFEPSTAKTQTDRQTNRHDTDIASLATSLPFVNHENTTSNLTMFWS

Summary

Description
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase. Participates in olfactory signal transduction.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase (By similarity).
Subunit
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Similarity
Belongs to the G-alpha family. G(s) subfamily.
Keywords
Complete proteome   GTP-binding   Lipoprotein   Magnesium   Metal-binding   Nucleotide-binding   Olfaction   Palmitate   Reference proteome   Sensory transduction   Transducer   Alternative splicing  
Feature
chain  Guanine nucleotide-binding protein G(s) subunit alpha
splice variant  In isoform A.
EMBL
EF188807    ABP01771.1    BABH01032652    KQ459460    KPJ00803.1    RSAL01000172    + More
RVE45102.1    EF188806    ABP01770.1    NWSH01000127    PCG79287.1    AGBW02014044    OWR42354.1    KQ459838    KPJ19718.1    GEBQ01029059    JAT10918.1    GEDC01024361    GEDC01014831    JAS12937.1    JAS22467.1    KK852854    KDR14965.1    GECU01025091    JAS82615.1    APGK01055950    APGK01055951    APGK01055952    APGK01055953    KB741271    KB632272    ENN71382.1    ERL91054.1    GECZ01014679    JAS55090.1    CVRI01000035    CRK92729.1    APCN01003263    DQ182017    AAAB01008986    EAA00295.1    GGFM01003697    MBW24448.1    GGFK01007984    MBW41305.1    ADMH02001457    ETN62507.1    GEHC01000716    JAV46929.1    CH477289    EAT44653.1    KZ150043    PZC74536.1    GGFJ01007014    MBW56155.1    GFPF01008226    MAA19372.1    GEDV01004988    JAP83569.1    KQ971351    EFA06420.1    GGMS01004148    MBY73351.1    AXCM01013867    GDQN01005520    GDQN01002809    JAT85534.1    JAT88245.1    DS231941    EDS28079.1    GANO01000948    JAB58923.1    GAPW01001972    JAC11626.1    GEFH01004472    JAP64109.1    GACK01002187    JAA62847.1    GFDL01011862    JAV23183.1    UFQT01000094    SSX19637.1    GFDF01006493    JAV07591.1    GEZM01010549    GEZM01010548    JAV93999.1    DS235858    EEB19096.1    CCAG010000714    GFXV01002616    MBW14421.1    AF010292    ABLF02041145    GGMR01001174    MBY13793.1    GANP01000899    JAB83569.1    ABJB010060355    ABJB010102119    ABJB010154221    ABJB010160689    ABJB010358359    ABJB010951610    ABJB011011254    DS788896    EEC10034.1    GALA01001089    JAA93763.1    CH933808    EDW09806.1    KRG04907.1    CH940648    EDW61166.1    KRF79830.1    CH479181    EDW31531.1    CM000071    EAL24812.1    CH963850    EDW74770.1    CM000158    KRK00515.1    KRK00516.1    M23233    M33998    M33997    AE013599    AY058572    AHN56593.1    CM002911    KMY96178.1    KMY96179.1    CH954179    KQS63084.1    KQS63086.1    GFWV01013279    MAA38008.1    CP012524    ALC42628.1    JXJN01002477    GFWV01014946    MAA39675.1    GEFM01005987    JAP69809.1    CH902619    EDV36264.1    GBXI01006766    GBXI01006029    JAD07526.1    JAD08263.1    GANP01003926    JAB80542.1    CH916367    EDW01911.1    GFDG01002205    JAV16594.1    CAEY01000784    JF273639    GDHC01005774    AEK80436.1    JAQ12855.1    GDHF01030676    GDHF01027518    GDHF01021188    GDHF01018398    GDHF01010919    GDHF01010352    JAI21638.1    JAI24796.1    JAI31126.1    JAI33916.1    JAI41395.1    JAI41962.1    GAKP01002195    GAKP01002194    GAKP01002193    GAKP01002192    GAKP01002191    JAC56758.1    GFPF01008225    MAA19371.1    GEDV01004987    JAP83570.1    GDKW01000343    JAI56252.1    ACPB03005095    AB488391    BAH98112.1    AY626794    AAU12181.1    GFTR01005702    JAW10724.1    GECL01002408    JAP03716.1    GBBI01002048    JAC16664.1    GBGD01001793    JAC87096.1    GL732526    EFX88427.1   
Pfam
PF00503   G-alpha
Interpro
IPR001019   Gprotein_alpha_su        + More
IPR000367   Gprotein_alpha_S       
IPR027417   P-loop_NTPase       
IPR011025   GproteinA_insert       
SUPFAM
SSF47895   SSF47895        + More
SSF52540   SSF52540       
Gene 3D
PDB
6EG8     E-value=2.52132e-130,     Score=1191

Ontologies

Topology

Length:
366
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
1.46088
Exp number, first 60 AAs:
0.01995
Total prob of N-in:
0.05207
outside
1  -  366
 
 

Population Genetic Test Statistics

Pi
190.350578
Theta
168.147556
Tajima's D
0.69289
CLR
0.327062
CSRT
0.567821608919554
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
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