Gene
KWMTBOMO12103
Pre Gene Modal
BGIBMGA004269
Annotation
G_protein_alpha_S_subunit_Gs2_[Bombyx_mori]
Full name
Guanine nucleotide-binding protein G(s) subunit alpha
+ More
G protein alpha s subunit
G protein alpha s subunit
Alternative Name
Adenylate cyclase-stimulating G alpha protein
Guanine nucleotide-binding protein G(s) subunit alpha
Guanine nucleotide-binding protein G(s) subunit alpha
Location in the cell
Nuclear Reliability : 2.601
Sequence
CDS
ATGCGCATCCTGCACGTCAACGGCTTCTCCGACAAGGAGCGCAAGGAGAAGATCGAGGACATCAAGAAGAACGTTCGAGATGCCATCATTACGATCACCGGTGCCATGAGTACCTTAACACCTCCGATTCCTCTCGAGAAACCGGAGAATAAACCACGCGTGGATTACATTCAGGACGTGGCGTCGCAGCCGGACTTCGACTACCCTTCGGAGTTCTACGAGCACACGGAGGCGCTGTGGAAGGACCAGGGCGTGCAGCGCACCTACGAGCGCAGCAACGAGTACCAGCTCATCGACAGTGCCAAATACTTCCTGGACAAGATCCACGTGATCAGACAGCCGGGCTACACGCCCACCGAGCAGGACGTCCTCCGCTGCCGGGTCCTCACATCCGGAATCTACCAGACGCAGTTCGTCGTGGACAAAGTTCACTTCCATATATTCGATGTCGGCGGACAACGCGACGAAAGACGCAAATGGATCCAGTGCTTCAACGATGTTACCGCGATCATCTTCGTGGCGGCCTGCTCCGCCTACAACATGGTGCTGCGCGAGGACCCCACGCAGAACCGGCTGCGCGAGTCCCTGGATCTGTTCAAGAGCATCTGGAACAACCGGTGGCTGCGGACCATCTCCGTCATCCTGTTCCTCAACAAGCAGGACCTGCTCGCCGAGAAGGTGCTGGCGGGGAAGTCTCGGCTCGAGGACTACTTCCACGAGTTCGCCCAGTACCAGACCCCGACTGACATGAAGCCAGACCCCAAAGATCACCCTGAAGTGACCCGCGCCAAGTTCTTCATTCGTGAGGAGTTTCTGCGCATCAGCACCGCCACGGGCGACGGCAAGCACGACTGCTACGCTCACTTCACGTGCGCCGTCGACACCGACAACATCCAACGAGTGTTCAACGGCTGCCGGAACATCATCCAGCGAGCTAACCAATGTGATTGCATTTACGTCTGTTTCGAACCGTCCACAGCAAAAACACAAACGGACAGACAAACCAACAGACACGACACGGACATAGCTTCGCTCGCGACCTCCCTGCCCTTTGTTAACCATGAAAATACAACGTCGAATTTGACGATGTTTTGGAGTTAG
Protein
MRILHVNGFSDKERKEKIEDIKKNVRDAIITITGAMSTLTPPIPLEKPENKPRVDYIQDVASQPDFDYPSEFYEHTEALWKDQGVQRTYERSNEYQLIDSAKYFLDKIHVIRQPGYTPTEQDVLRCRVLTSGIYQTQFVVDKVHFHIFDVGGQRDERRKWIQCFNDVTAIIFVAACSAYNMVLREDPTQNRLRESLDLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSRLEDYFHEFAQYQTPTDMKPDPKDHPEVTRAKFFIREEFLRISTATGDGKHDCYAHFTCAVDTDNIQRVFNGCRNIIQRANQCDCIYVCFEPSTAKTQTDRQTNRHDTDIASLATSLPFVNHENTTSNLTMFWS
Summary
Description
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase. Participates in olfactory signal transduction.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase (By similarity).
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase (By similarity).
Subunit
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Similarity
Belongs to the G-alpha family. G(s) subfamily.
Keywords
Complete proteome
GTP-binding
Lipoprotein
Magnesium
Metal-binding
Nucleotide-binding
Olfaction
Palmitate
Reference proteome
Sensory transduction
Transducer
Alternative splicing
Feature
chain Guanine nucleotide-binding protein G(s) subunit alpha
splice variant In isoform A.
splice variant In isoform A.
Uniprot
A4UIH1
H9J430
H9J4A5
A0A194Q5I1
A0A3S2LVU8
A4UIH0
+ More
A0A2A4K4W8 A0A212ELI8 A0A0N0PEF5 A0A1B6KHH6 A0A1B6CHJ4 A0A067QXK2 A0A1B6I6U4 N6TYL3 A0A1B6FY21 A0A182X073 A0A182YC99 A0A1J1I2Y7 A0A182P1E8 A0A182HPK4 Q7PD79 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 A0A1W7R6Z0 Q17E14 A0A182RSW4 A0A2W1BNU2 A0A182KBH2 A0A2M4BSU8 A0A224YZY8 A0A131YWJ3 D6WRY4 A0A2S2Q6Y1 A0A182WD25 A0A182M2F4 A0A182JGA6 A0A1E1WMN8 A0A1W4WR40 B0WHZ7 U5EXH7 A0A023ESA6 A0A131XB20 L7MG91 A0A182UB20 A0A1Q3F6P3 A0A336LTA6 A0A1L8DMF1 A0A1Y1N8F9 E0W0E0 A0A1B0F9I9 A0A1A9V624 A0A2H8TKC5 O16118 A0A1I8MH09 J9JJY9 A0A2S2N996 V5HXV0 B7PTW2 T1E238 B4KMB8 B4LNZ7 A0A1W4ULJ8 B4GCZ3 Q292P9 B4MRN1 A0A0R1DX90 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A293MDF1 A0A0M4E7G2 A0A1A9YJN9 A0A1B0ARM1 A0A293MKP0 A0A131XRZ4 B3MCN0 A0A0A1X9B5 V5HW56 B4J653 A0A1L8ED71 T1JUV9 A0A1A9ZRE3 G0ZGG8 A0A0K8UX10 A0A034WSM6 A0A224YXN7 A0A131YYI8 A0A0P4W079 T1IAH1 C7G305 Q66Q60 A0A224XI50 A0A0V0G6N7 A0A023F635 A0A069DTK5 A0A1A9WAB9 E9FWI4
A0A2A4K4W8 A0A212ELI8 A0A0N0PEF5 A0A1B6KHH6 A0A1B6CHJ4 A0A067QXK2 A0A1B6I6U4 N6TYL3 A0A1B6FY21 A0A182X073 A0A182YC99 A0A1J1I2Y7 A0A182P1E8 A0A182HPK4 Q7PD79 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 A0A1W7R6Z0 Q17E14 A0A182RSW4 A0A2W1BNU2 A0A182KBH2 A0A2M4BSU8 A0A224YZY8 A0A131YWJ3 D6WRY4 A0A2S2Q6Y1 A0A182WD25 A0A182M2F4 A0A182JGA6 A0A1E1WMN8 A0A1W4WR40 B0WHZ7 U5EXH7 A0A023ESA6 A0A131XB20 L7MG91 A0A182UB20 A0A1Q3F6P3 A0A336LTA6 A0A1L8DMF1 A0A1Y1N8F9 E0W0E0 A0A1B0F9I9 A0A1A9V624 A0A2H8TKC5 O16118 A0A1I8MH09 J9JJY9 A0A2S2N996 V5HXV0 B7PTW2 T1E238 B4KMB8 B4LNZ7 A0A1W4ULJ8 B4GCZ3 Q292P9 B4MRN1 A0A0R1DX90 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A293MDF1 A0A0M4E7G2 A0A1A9YJN9 A0A1B0ARM1 A0A293MKP0 A0A131XRZ4 B3MCN0 A0A0A1X9B5 V5HW56 B4J653 A0A1L8ED71 T1JUV9 A0A1A9ZRE3 G0ZGG8 A0A0K8UX10 A0A034WSM6 A0A224YXN7 A0A131YYI8 A0A0P4W079 T1IAH1 C7G305 Q66Q60 A0A224XI50 A0A0V0G6N7 A0A023F635 A0A069DTK5 A0A1A9WAB9 E9FWI4
Pubmed
17449058
19121390
26354079
22118469
24845553
23537049
+ More
25244985 17029251 12364791 20920257 23761445 17510324 28756777 28797301 26830274 18362917 19820115 24945155 28049606 25576852 28004739 20566863 9349521 25315136 25765539 24330624 17994087 18057021 15632085 17550304 2498884 2106072 10731132 12537572 12537569 12537568 12537573 12537574 16110336 17569856 17569867 22936249 25830018 26823975 25348373 27129103 25474469 26334808 21292972
25244985 17029251 12364791 20920257 23761445 17510324 28756777 28797301 26830274 18362917 19820115 24945155 28049606 25576852 28004739 20566863 9349521 25315136 25765539 24330624 17994087 18057021 15632085 17550304 2498884 2106072 10731132 12537572 12537569 12537568 12537573 12537574 16110336 17569856 17569867 22936249 25830018 26823975 25348373 27129103 25474469 26334808 21292972
EMBL
EF188807
ABP01771.1
BABH01032652
KQ459460
KPJ00803.1
RSAL01000172
+ More
RVE45102.1 EF188806 ABP01770.1 NWSH01000127 PCG79287.1 AGBW02014044 OWR42354.1 KQ459838 KPJ19718.1 GEBQ01029059 JAT10918.1 GEDC01024361 GEDC01014831 JAS12937.1 JAS22467.1 KK852854 KDR14965.1 GECU01025091 JAS82615.1 APGK01055950 APGK01055951 APGK01055952 APGK01055953 KB741271 KB632272 ENN71382.1 ERL91054.1 GECZ01014679 JAS55090.1 CVRI01000035 CRK92729.1 APCN01003263 DQ182017 AAAB01008986 EAA00295.1 GGFM01003697 MBW24448.1 GGFK01007984 MBW41305.1 ADMH02001457 ETN62507.1 GEHC01000716 JAV46929.1 CH477289 EAT44653.1 KZ150043 PZC74536.1 GGFJ01007014 MBW56155.1 GFPF01008226 MAA19372.1 GEDV01004988 JAP83569.1 KQ971351 EFA06420.1 GGMS01004148 MBY73351.1 AXCM01013867 GDQN01005520 GDQN01002809 JAT85534.1 JAT88245.1 DS231941 EDS28079.1 GANO01000948 JAB58923.1 GAPW01001972 JAC11626.1 GEFH01004472 JAP64109.1 GACK01002187 JAA62847.1 GFDL01011862 JAV23183.1 UFQT01000094 SSX19637.1 GFDF01006493 JAV07591.1 GEZM01010549 GEZM01010548 JAV93999.1 DS235858 EEB19096.1 CCAG010000714 GFXV01002616 MBW14421.1 AF010292 ABLF02041145 GGMR01001174 MBY13793.1 GANP01000899 JAB83569.1 ABJB010060355 ABJB010102119 ABJB010154221 ABJB010160689 ABJB010358359 ABJB010951610 ABJB011011254 DS788896 EEC10034.1 GALA01001089 JAA93763.1 CH933808 EDW09806.1 KRG04907.1 CH940648 EDW61166.1 KRF79830.1 CH479181 EDW31531.1 CM000071 EAL24812.1 CH963850 EDW74770.1 CM000158 KRK00515.1 KRK00516.1 M23233 M33998 M33997 AE013599 AY058572 AHN56593.1 CM002911 KMY96178.1 KMY96179.1 CH954179 KQS63084.1 KQS63086.1 GFWV01013279 MAA38008.1 CP012524 ALC42628.1 JXJN01002477 GFWV01014946 MAA39675.1 GEFM01005987 JAP69809.1 CH902619 EDV36264.1 GBXI01006766 GBXI01006029 JAD07526.1 JAD08263.1 GANP01003926 JAB80542.1 CH916367 EDW01911.1 GFDG01002205 JAV16594.1 CAEY01000784 JF273639 GDHC01005774 AEK80436.1 JAQ12855.1 GDHF01030676 GDHF01027518 GDHF01021188 GDHF01018398 GDHF01010919 GDHF01010352 JAI21638.1 JAI24796.1 JAI31126.1 JAI33916.1 JAI41395.1 JAI41962.1 GAKP01002195 GAKP01002194 GAKP01002193 GAKP01002192 GAKP01002191 JAC56758.1 GFPF01008225 MAA19371.1 GEDV01004987 JAP83570.1 GDKW01000343 JAI56252.1 ACPB03005095 AB488391 BAH98112.1 AY626794 AAU12181.1 GFTR01005702 JAW10724.1 GECL01002408 JAP03716.1 GBBI01002048 JAC16664.1 GBGD01001793 JAC87096.1 GL732526 EFX88427.1
RVE45102.1 EF188806 ABP01770.1 NWSH01000127 PCG79287.1 AGBW02014044 OWR42354.1 KQ459838 KPJ19718.1 GEBQ01029059 JAT10918.1 GEDC01024361 GEDC01014831 JAS12937.1 JAS22467.1 KK852854 KDR14965.1 GECU01025091 JAS82615.1 APGK01055950 APGK01055951 APGK01055952 APGK01055953 KB741271 KB632272 ENN71382.1 ERL91054.1 GECZ01014679 JAS55090.1 CVRI01000035 CRK92729.1 APCN01003263 DQ182017 AAAB01008986 EAA00295.1 GGFM01003697 MBW24448.1 GGFK01007984 MBW41305.1 ADMH02001457 ETN62507.1 GEHC01000716 JAV46929.1 CH477289 EAT44653.1 KZ150043 PZC74536.1 GGFJ01007014 MBW56155.1 GFPF01008226 MAA19372.1 GEDV01004988 JAP83569.1 KQ971351 EFA06420.1 GGMS01004148 MBY73351.1 AXCM01013867 GDQN01005520 GDQN01002809 JAT85534.1 JAT88245.1 DS231941 EDS28079.1 GANO01000948 JAB58923.1 GAPW01001972 JAC11626.1 GEFH01004472 JAP64109.1 GACK01002187 JAA62847.1 GFDL01011862 JAV23183.1 UFQT01000094 SSX19637.1 GFDF01006493 JAV07591.1 GEZM01010549 GEZM01010548 JAV93999.1 DS235858 EEB19096.1 CCAG010000714 GFXV01002616 MBW14421.1 AF010292 ABLF02041145 GGMR01001174 MBY13793.1 GANP01000899 JAB83569.1 ABJB010060355 ABJB010102119 ABJB010154221 ABJB010160689 ABJB010358359 ABJB010951610 ABJB011011254 DS788896 EEC10034.1 GALA01001089 JAA93763.1 CH933808 EDW09806.1 KRG04907.1 CH940648 EDW61166.1 KRF79830.1 CH479181 EDW31531.1 CM000071 EAL24812.1 CH963850 EDW74770.1 CM000158 KRK00515.1 KRK00516.1 M23233 M33998 M33997 AE013599 AY058572 AHN56593.1 CM002911 KMY96178.1 KMY96179.1 CH954179 KQS63084.1 KQS63086.1 GFWV01013279 MAA38008.1 CP012524 ALC42628.1 JXJN01002477 GFWV01014946 MAA39675.1 GEFM01005987 JAP69809.1 CH902619 EDV36264.1 GBXI01006766 GBXI01006029 JAD07526.1 JAD08263.1 GANP01003926 JAB80542.1 CH916367 EDW01911.1 GFDG01002205 JAV16594.1 CAEY01000784 JF273639 GDHC01005774 AEK80436.1 JAQ12855.1 GDHF01030676 GDHF01027518 GDHF01021188 GDHF01018398 GDHF01010919 GDHF01010352 JAI21638.1 JAI24796.1 JAI31126.1 JAI33916.1 JAI41395.1 JAI41962.1 GAKP01002195 GAKP01002194 GAKP01002193 GAKP01002192 GAKP01002191 JAC56758.1 GFPF01008225 MAA19371.1 GEDV01004987 JAP83570.1 GDKW01000343 JAI56252.1 ACPB03005095 AB488391 BAH98112.1 AY626794 AAU12181.1 GFTR01005702 JAW10724.1 GECL01002408 JAP03716.1 GBBI01002048 JAC16664.1 GBGD01001793 JAC87096.1 GL732526 EFX88427.1
Proteomes
UP000005204
UP000053268
UP000283053
UP000218220
UP000007151
UP000053240
+ More
UP000027135 UP000019118 UP000030742 UP000076407 UP000076408 UP000183832 UP000075885 UP000075840 UP000007062 UP000000673 UP000069272 UP000008820 UP000075900 UP000075881 UP000007266 UP000075920 UP000075883 UP000075880 UP000192223 UP000002320 UP000075902 UP000009046 UP000092444 UP000078200 UP000095301 UP000007819 UP000001555 UP000009192 UP000008792 UP000192221 UP000008744 UP000001819 UP000007798 UP000002282 UP000000803 UP000008711 UP000092553 UP000092443 UP000092460 UP000007801 UP000001070 UP000015104 UP000092445 UP000015103 UP000091820 UP000000305
UP000027135 UP000019118 UP000030742 UP000076407 UP000076408 UP000183832 UP000075885 UP000075840 UP000007062 UP000000673 UP000069272 UP000008820 UP000075900 UP000075881 UP000007266 UP000075920 UP000075883 UP000075880 UP000192223 UP000002320 UP000075902 UP000009046 UP000092444 UP000078200 UP000095301 UP000007819 UP000001555 UP000009192 UP000008792 UP000192221 UP000008744 UP000001819 UP000007798 UP000002282 UP000000803 UP000008711 UP000092553 UP000092443 UP000092460 UP000007801 UP000001070 UP000015104 UP000092445 UP000015103 UP000091820 UP000000305
Pfam
PF00503 G-alpha
Interpro
Gene 3D
CDD
ProteinModelPortal
A4UIH1
H9J430
H9J4A5
A0A194Q5I1
A0A3S2LVU8
A4UIH0
+ More
A0A2A4K4W8 A0A212ELI8 A0A0N0PEF5 A0A1B6KHH6 A0A1B6CHJ4 A0A067QXK2 A0A1B6I6U4 N6TYL3 A0A1B6FY21 A0A182X073 A0A182YC99 A0A1J1I2Y7 A0A182P1E8 A0A182HPK4 Q7PD79 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 A0A1W7R6Z0 Q17E14 A0A182RSW4 A0A2W1BNU2 A0A182KBH2 A0A2M4BSU8 A0A224YZY8 A0A131YWJ3 D6WRY4 A0A2S2Q6Y1 A0A182WD25 A0A182M2F4 A0A182JGA6 A0A1E1WMN8 A0A1W4WR40 B0WHZ7 U5EXH7 A0A023ESA6 A0A131XB20 L7MG91 A0A182UB20 A0A1Q3F6P3 A0A336LTA6 A0A1L8DMF1 A0A1Y1N8F9 E0W0E0 A0A1B0F9I9 A0A1A9V624 A0A2H8TKC5 O16118 A0A1I8MH09 J9JJY9 A0A2S2N996 V5HXV0 B7PTW2 T1E238 B4KMB8 B4LNZ7 A0A1W4ULJ8 B4GCZ3 Q292P9 B4MRN1 A0A0R1DX90 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A293MDF1 A0A0M4E7G2 A0A1A9YJN9 A0A1B0ARM1 A0A293MKP0 A0A131XRZ4 B3MCN0 A0A0A1X9B5 V5HW56 B4J653 A0A1L8ED71 T1JUV9 A0A1A9ZRE3 G0ZGG8 A0A0K8UX10 A0A034WSM6 A0A224YXN7 A0A131YYI8 A0A0P4W079 T1IAH1 C7G305 Q66Q60 A0A224XI50 A0A0V0G6N7 A0A023F635 A0A069DTK5 A0A1A9WAB9 E9FWI4
A0A2A4K4W8 A0A212ELI8 A0A0N0PEF5 A0A1B6KHH6 A0A1B6CHJ4 A0A067QXK2 A0A1B6I6U4 N6TYL3 A0A1B6FY21 A0A182X073 A0A182YC99 A0A1J1I2Y7 A0A182P1E8 A0A182HPK4 Q7PD79 A0A2M3Z7N5 A0A2M4AKI7 W5JDR0 A0A182FTX6 A0A1W7R6Z0 Q17E14 A0A182RSW4 A0A2W1BNU2 A0A182KBH2 A0A2M4BSU8 A0A224YZY8 A0A131YWJ3 D6WRY4 A0A2S2Q6Y1 A0A182WD25 A0A182M2F4 A0A182JGA6 A0A1E1WMN8 A0A1W4WR40 B0WHZ7 U5EXH7 A0A023ESA6 A0A131XB20 L7MG91 A0A182UB20 A0A1Q3F6P3 A0A336LTA6 A0A1L8DMF1 A0A1Y1N8F9 E0W0E0 A0A1B0F9I9 A0A1A9V624 A0A2H8TKC5 O16118 A0A1I8MH09 J9JJY9 A0A2S2N996 V5HXV0 B7PTW2 T1E238 B4KMB8 B4LNZ7 A0A1W4ULJ8 B4GCZ3 Q292P9 B4MRN1 A0A0R1DX90 P20354-2 A0A0B4LGI1 A0A0J9RJG8 A0A0Q5VQ94 A0A293MDF1 A0A0M4E7G2 A0A1A9YJN9 A0A1B0ARM1 A0A293MKP0 A0A131XRZ4 B3MCN0 A0A0A1X9B5 V5HW56 B4J653 A0A1L8ED71 T1JUV9 A0A1A9ZRE3 G0ZGG8 A0A0K8UX10 A0A034WSM6 A0A224YXN7 A0A131YYI8 A0A0P4W079 T1IAH1 C7G305 Q66Q60 A0A224XI50 A0A0V0G6N7 A0A023F635 A0A069DTK5 A0A1A9WAB9 E9FWI4
PDB
6EG8
E-value=2.52132e-130,
Score=1191
Ontologies
GO
GO:0005525
GO:0007186
GO:0031683
GO:0003924
GO:0007165
GO:0001664
GO:0007188
GO:0007608
GO:0046872
GO:0005834
GO:0007191
GO:0007268
GO:0005604
GO:0007528
GO:0050916
GO:2000253
GO:0010353
GO:0007476
GO:0005886
GO:0007632
GO:0002165
GO:0007611
GO:0048148
GO:0004871
GO:0019001
GO:0008033
GO:0003676
GO:0016787
PANTHER
Topology
Length:
366
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
1.46088
Exp number, first 60 AAs:
0.01995
Total prob of N-in:
0.05207
outside
1 - 366
Population Genetic Test Statistics
Pi
190.350578
Theta
168.147556
Tajima's D
0.69289
CLR
0.327062
CSRT
0.567821608919554
Interpretation
Uncertain
