Gene

KWMTBOMO12069

Pre Gene Modal

BGIBMGA004292

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr20(-):6720185-6731066      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.505

CDS

ATGAAGTTCGCTCTATTGTTCGTATTGACCGCGATCGTCGCGGTGTCGACTAATGAAGTGGCTGACCCCAGATCCACTGACAGAGCTAACGCTTTGAGTATCGGAAGTATTACTTCAAGTGATAGACTCTTACGAAGCTTTGTTGTGAGCCGTGCTGCTACAATTAACTGGCGGGTTCTCAACGTGAGATTCACGGCGCCTGCCGGTAGACGCGTCAGGGCTGTCCGCGTCCGAGGATCGACACAGTTCACAAGGGTCCGCCGCACCGGAGGCGGCGTCGGCTTCACTTTCGTGGAACTCACACACCACAACCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATGATCTCGCCTTCGATATCGTCGCTCCGCTAACACCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTGGACATAGCGTTATTAAAAAACGTAACTCTGAGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGACTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACTCGGACTCTACCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCAACATTAGATAGATCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGATAATATTAGGGAACTCTTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGGTCTCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGTGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACCGCTTAGCTTGTACTCTCAAATCGGATACGGTAGTAACTATGCCCTCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTTGATGATGACGAAAAAGCAGAGTTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGTCTCCTTGCCCCCCTCGGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGTGAACTGTAACACCACACCGCGGGAAAGATCCCGCGGTGTGGAAAGAAGCGGACGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGCGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAACGGTTTGATTTTCAAACTATTCAACATGGGTGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTTCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTTAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCCAGTAGAAACAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGTATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGTCAATCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCTTTACAATCCCGCTTTTGCAGATTAGCCGTCGGAGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCTATACAGAAATACATGAAGTCAGCGTCGGAACGGTACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTAGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCACTAGACGCCTTCAGCTCTAGGAGCAGGCTTAGGGACCTCGTAAAGTTTGCGGTTTGTGTGCGTCAGATGGAACAATGGGTTATGAAAGGTGGCCCTCAGGAAGCTGATCAGGAAAACAGAAAAACAGAGATGAAGTTCGCTCTATTGTTCGTATTGACCGCGATCGTCGCGGTGTCGACTAATGAAGTGGCTGACCCCAGATCCACTGATAGAGCTAACGCTTTGAGTATCGGAAGTATTACTTCAAGTGATAGACTCTTACGGAGCTTTGTTGTGAGCCGTGCTGCTACAATTAACTCGCGGGTTGTCAACGTGAGGTTCACGGCGCCTGCCGGTAGACGCGTCAGGGCTGTCCGCGTCCGAGGATCGACACAGTTCGCGAGGGTCCGCCGCACCGGAGGCGGCGTCGGCTTCACTTTCGTGAATCTTCAGTTCGTGAACGCGCCGCGAAGAGGATTTCGCTTTACCGTACAAATTTGGGGACGCTAA

Protein

MKFALLFVLTAIVAVSTNEVADPRSTDRANALSIGSITSSDRLLRSFVVSRAATINWRVLNVRFTAPAGRRVRAVRVRGSTQFTRVRRTGGGVGFTFVELTHHNPNGRRLDALVDDLAFDIVAPLTPTHYPLNIAHRPDILDIALLKNVTLSLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNSDSTPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDNIRELFRAKNASIRAYDRSPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYRLACTLKSDTVVTMPSLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRVSLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMVNCNTTPRERSRGVERSGRKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQAHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSFPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFSQSIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIQKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSRSRLRDLVKFAVCVRQMEQWVMKGGPQEADQENRKTEMKFALLFVLTAIVAVSTNEVADPRSTDRANALSIGSITSSDRLLRSFVVSRAATINSRVVNVRFTAPAGRRVRAVRVRGSTQFARVRRTGGGVGFTFVNLQFVNAPRRGFRFTVQIWGR

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   V5GNF3   A0A139W8G9   A0A2S2QEE0   A0A023EYS8   X1WLB2   X1WNI2   J9LC21   A0A224XB44   A0A2S2PPK8   A0A224XF24   X1WZH0   A0A2J7R7D0   A0A1Y1LKN6   A0A0J7MYU2   A0A2S2PX53   A0A224X6U5   A0A2J7PQB5   Q95SX7   A0A224XIB0   A0A2S2NGV8   A0A2H8TF37   J9KPF1   A0A224X6T4   A0A023EZE6   A0A2J7PU96   A0A224X6S1   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   Q07995   A0A2J7QFL0   A0A224X746   A0A1Y1KFR3   A0A2J7R2E1   A0A2J7RKP3   J9JZG6   A0A0V0G5B6   A0A2J7Q0Q6   A0A2S2R9D4   A0A2J7R6U1   A0A2A4IUM2   A0A2J7PVX3   J9LFC9   J9KSK5   A0A0A9YJ00   Q9NBX4   A0A2S2PBB4   A0A2J7R8R8   A0A2S2N6Q7   A0A2J7Q6J2   A0A2M4BD67   A0A2A4K918   A0A2M4BDV6   A0A0A9YU04   A0A2S2PJG2   A0A069DZL8   A0A142LX26   A0A087UGF5   A0A1B6EGD8   A0A142LX49   A0A2M4BEF4   A0A2M4BEZ9  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    7753626    12537569    8387152    25401762    11405632    26334808    25527032   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    KQ973342    KXZ75569.1    GGMS01006359    MBY75562.1    GBBI01004395    JAC14317.1    ABLF02042518    ABLF02057746    ABLF02008153    ABLF02008462    ABLF02008464    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GFTR01008262    JAW08164.1    GGMR01018716    MBY31335.1    GFTR01008038    JAW08388.1    ABLF02034467    NEVH01006736    PNF36716.1    GEZM01053022    JAV74219.1    LBMM01013518    KMQ85605.1    GGMS01000737    MBY69940.1    GFTR01008251    JAW08175.1    NEVH01022639    PNF18527.1    AY060438    AAL25477.1    GFTR01008246    JAW08180.1    GGMR01003407    MBY16026.1    GFXV01000908    MBW12713.1    ABLF02041767    GFTR01008261    JAW08165.1    GBBI01004571    JAC14141.1    NEVH01021205    PNF19912.1    GFTR01008271    JAW08155.1    NEVH01011985    PNF31054.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    S59870    AAB26437.2    NEVH01014858    PNF27387.1    GFTR01008151    JAW08275.1    GEZM01084969    JAV60363.1    NEVH01007838    PNF34986.1    NEVH01002716    PNF41415.1    ABLF02037436    GECL01003538    JAP02586.1    NEVH01019964    PNF22161.1    GGMS01017365    MBY86568.1    NEVH01006754    PNF36554.1    NWSH01007753    PCG62823.1    NEVH01020940    PNF20481.1    ABLF02023911    ABLF02014118    ABLF02014121    ABLF02054790    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    AF237761    AAF81411.1    GGMR01014053    MBY26672.1    NEVH01006721    PNF37225.1    GGMR01000226    MBY12845.1    NEVH01017470    PNF24199.1    GGFJ01001858    MBW50999.1    NWSH01000032    PCG80496.1    GGFJ01001857    MBW50998.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GGMR01016905    MBY29524.1    GBGD01000415    JAC88474.1    KU543673    AMS38352.1    KK119692    KFM76444.1    GEDC01000337    JAS36961.1    KU543685    AMS38375.1    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000036403    UP000218220    + More
UP000054359   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q95SX7    Q9NBX4   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   V5GNF3   A0A139W8G9   A0A2S2QEE0   A0A023EYS8   X1WLB2   X1WNI2   J9LC21   A0A224XB44   A0A2S2PPK8   A0A224XF24   X1WZH0   A0A2J7R7D0   A0A1Y1LKN6   A0A0J7MYU2   A0A2S2PX53   A0A224X6U5   A0A2J7PQB5   Q95SX7   A0A224XIB0   A0A2S2NGV8   A0A2H8TF37   J9KPF1   A0A224X6T4   A0A023EZE6   A0A2J7PU96   A0A224X6S1   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   Q07995   A0A2J7QFL0   A0A224X746   A0A1Y1KFR3   A0A2J7R2E1   A0A2J7RKP3   J9JZG6   A0A0V0G5B6   A0A2J7Q0Q6   A0A2S2R9D4   A0A2J7R6U1   A0A2A4IUM2   A0A2J7PVX3   J9LFC9   J9KSK5   A0A0A9YJ00   Q9NBX4   A0A2S2PBB4   A0A2J7R8R8   A0A2S2N6Q7   A0A2J7Q6J2   A0A2M4BD67   A0A2A4K918   A0A2M4BDV6   A0A0A9YU04   A0A2S2PJG2   A0A069DZL8   A0A142LX26   A0A087UGF5   A0A1B6EGD8   A0A142LX49   A0A2M4BEF4   A0A2M4BEZ9  

KEGG

101738604    no KO assigned | (RefSeq) uncharacterized LOC101738604

GO

GO:0003964   GO:0004519   GO:0006313  

SignalP

Position:   1 - 17,         Likelihood:  0.994537

 

 

Length:

1016

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.40069

Exp number, first 60 AAs:

0.06195

Total prob of N-in:

0.00343

outside

1  -  1016

 

 

Pi

19.34702

Theta

195.457492

Tajima's D

-1.772264

CLR

1087.934635

CSRT

0.031698415079246

Interpretation

Possibly Positive selection