Gene

KWMTBOMO12064

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr20(+):6646437-6648986      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.522

CDS

ATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAACCCGGACTCTATCCCGTCTTCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCTTACGACAGGTATCCTACCGCGGAAAATCGTATTCGAATGCGTGCCCTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGATGGTCTGATTTCTTAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGCCGACTCGCGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTTCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCATCGGATGCGTTACCACCCGTCACCCCGATAGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCACCTGGTTCCGACGGTATATCTAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTAGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAATGGTTTGATTTTCAAACTATTCAACATGGGCGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTCTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTTCCGCAAGGCTCTGTCCTCTCACCCCTACTATTTAGCTTATTCGTCAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCTAGTAGAAATAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTATTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGGATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGACAACCCATACCCTGGGCCAGGAAGGTCCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCTGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCTGTCGGGGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACTTGGGCCTCGAATCAATTCGGAAATACATGAAGTCAGCGTCGAAACGATACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTTGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTTGCATTAGATGCCTTCAGCTGTAATACTAGGGGCAGGCTTAGGGACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAACCTAA

Protein

MKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFNPDSIPSSQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRYPTAENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTLKSDTVVTMPPLVGPSGRLAAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDALPPVTPIEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFRQPIPWARKVLGVTLDASMTFRPHIKSVCDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKYMKSASKRYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSCNTRGRLRDPGNRTRRTRQRGRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   V5GNF3   A0A139W8G9   A0A2S2PR14   J9KKL3   X1WLB2   A0A2S2Q352   A0A2S2QEE0   A0A3N5Z7I3   A0A023EYS8   A0A224XF24   A0A2H8U0H5   A0A2S2PPK8   J9KCZ4   Q07995   J9KC83   X1WNI2   A0A224XB44   K7IN67   A0A2J7R7D0   A0A1Y1LKN6   A0A023EZE6   A0A2S2RAN7   A0A2J7RS81   A0A2S2NGV8   J9LC21   A0A023F6S4   A0A0C9RJA4   X1WZH0   A0A2M4BD67   A0A2M4BDV6   A0A2J7PQB5   A0A2S2N814   A0A2J7Q627   X1WN18   J9M522   A0A1Y1M7E9   A0A2S2Q383   A0A2J7R8R8   A0A2J7PVX3   Q95SX7   A0A2J7PDM0   A0A224X6U5   A0A224X6Q4   A0A069DZC5   A0A224XI99   A0A1Y1KFR3   A0A1L8DIZ6   A0A2S2PBB4   A0A069DW01   A0A2J7RL12   A0A2J7Q059   A0A2S2R9D4   X1WTA1   J9JS95   J9KPF1   A0A2J7QUJ9   A0A2J7QTW2   A0A023F7D1   A0A2J7RIW7   A0A2J7PMP6   A0A2J7R4B7   A0A2J7RM10   A0A2J7Q4F7   A0A2A4K8E7   A0A2J7RPU2   A0A224XIB0   A0A2J7RB54   J9LC15   A0A224X6S1   A0A2A4K918   A0A023F754   A0A2J7QFL0   A0A2J7R2E1   A0A2J7PU96   A0A2J7RKP3   A0A2J7Q0Q6  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
30086797    25474469    8387152    20075255    7753626    12537569    26334808   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    GALX01005359    JAB63107.1    KQ973342    KXZ75569.1    GGMR01019198    MBY31817.1    ABLF02029306    ABLF02029314    ABLF02060138    ABLF02042518    ABLF02057746    GGMS01002955    MBY72158.1    GGMS01006359    MBY75562.1    RPOV01000134    RPJ78669.1    GBBI01004395    JAC14317.1    GFTR01008038    JAW08388.1    GFXV01007093    MBW18898.1    GGMR01018716    MBY31335.1    ABLF02008463    S59870    AAB26437.2    ABLF02033757    ABLF02008153    ABLF02008462    ABLF02008464    GFTR01008262    JAW08164.1    NEVH01006736    PNF36716.1    GEZM01053022    JAV74219.1    GBBI01004571    JAC14141.1    GGMS01017914    MBY87117.1    NEVH01000269    PNF43694.1    GGMR01003407    MBY16026.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GBBI01001646    JAC17066.1    GBYB01008290    JAG78057.1    ABLF02034467    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    NEVH01022639    PNF18527.1    GGMR01000676    MBY13295.1    NEVH01017542    PNF24034.1    ABLF02021177    ABLF02027367    ABLF02066338    ABLF02024246    GEZM01038405    JAV81653.1    GGMS01002992    MBY72195.1    NEVH01006721    PNF37225.1    NEVH01020940    PNF20481.1    AY060438    AAL25477.1    NEVH01026386    PNF14434.1    GFTR01008251    JAW08175.1    GFTR01008279    JAW08147.1    GBGD01000880    JAC88009.1    GFTR01008256    JAW08170.1    GEZM01084969    JAV60363.1    GFDF01007661    JAV06423.1    GGMR01014053    MBY26672.1    GBGD01000799    JAC88090.1    NEVH01002704    PNF41489.1    NEVH01020071    PNF21969.1    GGMS01017365    MBY86568.1    ABLF02037660    ABLF02028535    ABLF02028545    ABLF02041767    NEVH01010546    PNF32261.1    NEVH01011193    PNF32021.1    GBBI01001570    JAC17142.1    NEVH01003017    PNF40781.1    NEVH01023962    PNF17612.1    NEVH01007443    PNF35684.1    NEVH01021586    NEVH01006600    NEVH01002584    PNF19589.1    PNF37419.1    PNF41868.1    NEVH01018383    PNF23463.1    NWSH01000032    PCG80497.1    NEVH01001355    PNF42855.1    GFTR01008246    JAW08180.1    NEVH01005938    PNF38077.1    ABLF02020655    ABLF02039168    ABLF02061060    GFTR01008271    JAW08155.1    PCG80496.1    GBBI01001642    JAC17070.1    NEVH01014858    PNF27387.1    NEVH01007838    PNF34986.1    NEVH01021205    PNF19912.1    NEVH01002716    PNF41415.1    NEVH01019964    PNF22161.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000002358    UP000235965    UP000218220    + More

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q95SX7   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   V5GNF3   A0A139W8G9   A0A2S2PR14   J9KKL3   X1WLB2   A0A2S2Q352   A0A2S2QEE0   A0A3N5Z7I3   A0A023EYS8   A0A224XF24   A0A2H8U0H5   A0A2S2PPK8   J9KCZ4   Q07995   J9KC83   X1WNI2   A0A224XB44   K7IN67   A0A2J7R7D0   A0A1Y1LKN6   A0A023EZE6   A0A2S2RAN7   A0A2J7RS81   A0A2S2NGV8   J9LC21   A0A023F6S4   A0A0C9RJA4   X1WZH0   A0A2M4BD67   A0A2M4BDV6   A0A2J7PQB5   A0A2S2N814   A0A2J7Q627   X1WN18   J9M522   A0A1Y1M7E9   A0A2S2Q383   A0A2J7R8R8   A0A2J7PVX3   Q95SX7   A0A2J7PDM0   A0A224X6U5   A0A224X6Q4   A0A069DZC5   A0A224XI99   A0A1Y1KFR3   A0A1L8DIZ6   A0A2S2PBB4   A0A069DW01   A0A2J7RL12   A0A2J7Q059   A0A2S2R9D4   X1WTA1   J9JS95   J9KPF1   A0A2J7QUJ9   A0A2J7QTW2   A0A023F7D1   A0A2J7RIW7   A0A2J7PMP6   A0A2J7R4B7   A0A2J7RM10   A0A2J7Q4F7   A0A2A4K8E7   A0A2J7RPU2   A0A224XIB0   A0A2J7RB54   J9LC15   A0A224X6S1   A0A2A4K918   A0A023F754   A0A2J7QFL0   A0A2J7R2E1   A0A2J7PU96   A0A2J7RKP3   A0A2J7Q0Q6  

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

734

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.00855000000001

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04097

outside

1  -  734

 

 

Pi

13.112453

Theta

19.787502

Tajima's D

-2.114994

CLR

0

CSRT

0.00874956252187391

Interpretation

Uncertain