Gene

KWMTBOMO12057  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004302

Annotation

PREDICTED:_eukaryotic_translation_initiation_factor_2_alpha_subunit_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr20(-):6512174-6516599      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.958

CDS

ATGCCGTTGTCGTGTCGATTTTATCAAGAGAAATATCCGGAAGTTGAAGATGTGGTGATGGTGAACGTTAGATCCATCGCAGAGATGGGAGCATACGTCCACCTTCTAGAATACAATAATATAGAGGGCATGATCTTGCTATCTGAGCTTTCCAGAAGACGTATCAGATCCATTAACAAATTGATCCGAGTGGGAAAGACTGAACCGGTTGTCGTTATCAGAGTGGACAAAGAAAAAGGATACATAGACTTATCGAAACGTCGTGTATCTGCTGAAGATATATACAAGTGCACAGAACGCTACGCAAAAGCAAAAGCAGTAAACTCGATCCTGCGACATGTAGCAGAGCTCCTCCATTATGAAACTTCTGAGCAATTGGAAGAACTTTATAAAAAAACAGCTTGGTACTTTGAAGAGAAATATAAGAAGAAAGCCTCGGCATATGACTTCTTCAAACAAGCAGCTGTAGACCCATCAGTACTCGATGAATGTGGCTTAGATGAAGAAACTAAGGATGTCCTCTTAGCTAATATTAAAAGGAAACTGACTTCGCAAGCAGTGAAGATCCGTGCTGACATTGAGTGTGCTTGCTATGGTTATGAAGGCATTGATGCTGTACGAGCAGCTTTGAAAGCTGGTCTAGCTCTGTCTACAGTGGACATGCCAATCAAAATTAATCTTATTGCCCCACCTTTGTATGTAATGACTACCTCAACTCCTGAGAAGACTGACGGTCTCAAAGCATTACAAGACGCAATCGACAAAATTCAAGAGAACATCACAGAAGCAGGTGGAGTCTTCAACATTCAGATGGCGCCTAAAGTGGTGACAGCGACAGACGAGGCAGAGTTGGCCCGACAGATGGAACGCGCGGAGGCTGAAAACGCTGAAGTCGCTGGTGATTCTGCCGAGGAAGACGAGGATCAAGGTATGGGCGATGCTAACATGGATGGTGAACCGCAACAGAACGGCGCTTCGGACGAAGAAGACGACAATTGA

Protein

MPLSCRFYQEKYPEVEDVVMVNVRSIAEMGAYVHLLEYNNIEGMILLSELSRRRIRSINKLIRVGKTEPVVVIRVDKEKGYIDLSKRRVSAEDIYKCTERYAKAKAVNSILRHVAELLHYETSEQLEELYKKTAWYFEEKYKKKASAYDFFKQAAVDPSVLDECGLDEETKDVLLANIKRKLTSQAVKIRADIECACYGYEGIDAVRAALKAGLALSTVDMPIKINLIAPPLYVMTTSTPEKTDGLKALQDAIDKIQENITEAGGVFNIQMAPKVVTATDEAELARQMERAEAENAEVAGDSAEEDEDQGMGDANMDGEPQQNGASDEEDDN

Uniprot

H9J463   Q4TTE0   A0A1E1W1Q9   Q8I6Y8   A0A212F2W3   A0A2A4JZF7   + More
A0A0B5KT04   A0A3S2TPR7   S4NQ02   I4DKX1   A0A194Q642   A0A026WVM6   A0A232F0Z6   E2B063   K7J3L3   A0A2A3ESI1   A0A195CPS5   A0A0J7L5Q7   A0A195DVQ2   A0A158NQF0   A0A2J7RGM5   A0A0C9Q3G6   A0A1W4XBW3   A0A151I2D4   E9IDH5   A0A1Y1MEM0   A0A067RES0   A0A195EWA3   A0A1B6HE60   A0A0V0G5V4   A0A2P8Y3G6   A0A069DRN0   A0A023F987   R4WK76   A0A224XS75   R4G619   D6WT44   A0A1B6KMC5   A0A1B6GE77   A0A336LWL3   A0A0A9YLY1   J3JV47   A0A1L8DSF3   A0A2S2RAQ6   A0A1B6CLI4   A0A0K8TNB5   A0A084WCC5   J9K8Z1   A0A2H8TXA5   C4WV63   A0A2S2NND8   A0A1J1HEA7   E0W0E5   A0A2M4BSX9   U5EME2   A0A2M3Z339   A0A2S2NWY1   A0A2M4A4D3   T1DGR1   W5JU13   B0WUX0   A0A1Q3F5I1   A0A182NZI9   A0A182JNF1   A0A182X5J2   A0A182LHQ8   Q7QHH7   A0A182HFW3   A0A182VP07   A0A0P5CUC2   A0A0P5BB66   E9FZ38   A0A182SLN2   A0A182MBR8   A0A182YED0   A0A182IPC7   A0A182WDF1   A0A0P4Z0J6   A0A0P5YB30   A0A182MXJ8   A0A0P5KY04   A0A182H9U0   A0A1S4G076   A0A164TVR0   A0A0P5YAY2   Q16IG9   A0A0P6JSN3   A0A0P6A739   A0A023EPX3   A0A023ES16   A0A0N8DBY6   A0A1D2MG79   A0A182RTG2   A0A0P5UCK6   A0A087U5Q1   B4M340   T1H965   B4L5N5   A0A0M4ENN8   A0A226EY44  

Pubmed

19121390    12542638    22118469    23622113    22651552    26354079    + More
24508170    30249741    28648823    20798317    20075255    21347285    21282665    28004739    24845553    29403074    26334808    25474469    23691247    18362917    19820115    25401762    26823975    22516182    23537049    26369729    24438588    20566863    20920257    23761445    20966253    12364791    21292972    25244985    26483478    17510324    24945155    27289101    17994087   

EMBL

BABH01032560    DQ073458    AAY54260.1    GDQN01010127    JAT80927.1    AF447395    + More
ODYU01006952    AAO15491.1    SOQ49269.1    AGBW02010674    OWR48062.1    NWSH01000349    PCG77156.1    KM923791    AJG43850.1    RSAL01000029    RVE51815.1    GAIX01013381    JAA79179.1    AK401939    BAM18561.1    KQ459460    KPJ00834.1    KK107085    QOIP01000008    EZA60048.1    RLU19953.1    NNAY01001394    OXU24127.1    GL444408    EFN60920.1    KZ288186    PBC34743.1    KQ977444    KYN02711.1    LBMM01000668    KMQ97829.1    KQ980322    KYN16634.1    ADTU01023182    NEVH01003767    PNF39960.1    GBYB01008643    JAG78410.1    KQ976539    KYM81297.1    GL762454    EFZ21367.1    GEZM01033305    JAV84269.1    KK852513    KDR22257.1    KQ981948    KYN32555.1    GECU01034689    JAS73017.1    GECL01003346    JAP02778.1    PYGN01000972    PSN38808.1    GBGD01002161    JAC86728.1    GBBI01000646    JAC18066.1    AK418005    BAN21220.1    GFTR01005044    JAW11382.1    GAHY01000015    JAA77495.1    KQ971354    EFA07164.1    GEBQ01027391    JAT12586.1    GECZ01009048    JAS60721.1    UFQT01000175    SSX21139.1    GBHO01010400    GBHO01010399    GBRD01012325    GDHC01016849    JAG33204.1    JAG33205.1    JAG53499.1    JAQ01780.1    APGK01052264    BT127113    KB741211    KB632263    AEE62075.1    ENN72815.1    ERL90949.1    GFDF01004780    JAV09304.1    GGMS01017845    MBY87048.1    GEDC01023002    JAS14296.1    GDAI01001739    JAI15864.1    ATLV01022651    KE525335    KFB47869.1    ABLF02023534    GFXV01007082    MBW18887.1    AK341375    BAH71783.1    GGMR01005833    MBY18452.1    CVRI01000001    CRK86163.1    DS235858    EEB19101.1    GGFJ01007046    MBW56187.1    GANO01001069    JAB58802.1    GGFM01002180    MBW22931.1    GGMR01009112    MBY21731.1    GGFK01002353    MBW35674.1    GAMD01002676    JAA98914.1    ADMH02000484    ETN66254.1    DS232111    EDS35113.1    GFDL01012282    JAV22763.1    AAAB01008816    EAA05222.4    APCN01005428    GDIP01181591    JAJ41811.1    GDIP01186947    GDIQ01191569    GDIP01091354    JAJ36455.1    JAK60156.1    GL732527    EFX87668.1    AXCM01003735    GDIP01224141    JAI99260.1    GDIP01060402    JAM43313.1    GDIQ01177628    JAK74097.1    JXUM01121588    KQ566515    KXJ70062.1    LRGB01001707    KZS10800.1    GDIP01060401    JAM43314.1    CH478078    EAT34061.1    GDIQ01010023    JAN84714.1    GDIP01033651    JAM70064.1    GAPW01002006    JAC11592.1    GAPW01002082    JAC11516.1    GDIP01048759    JAM54956.1    LJIJ01001355    ODM92007.1    GDIP01115011    JAL88703.1    KK118310    KFM72690.1    CH940651    EDW65215.1    ACPB03016173    ACPB03016174    CH933811    EDW06494.1    CP012528    ALC49658.1    LNIX01000001    OXA62565.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000283053    UP000053268    UP000053097    + More
UP000279307    UP000215335    UP000000311    UP000002358    UP000242457    UP000078542    UP000036403    UP000078492    UP000005205    UP000235965    UP000192223    UP000078540    UP000027135    UP000078541    UP000245037    UP000007266    UP000019118    UP000030742    UP000030765    UP000007819    UP000183832    UP000009046    UP000000673    UP000002320    UP000075885    UP000075881    UP000076407    UP000075882    UP000007062    UP000075840    UP000075903    UP000000305    UP000075901    UP000075883    UP000076408    UP000075880    UP000075920    UP000075884    UP000069940    UP000249989    UP000076858    UP000008820    UP000094527    UP000075900    UP000054359    UP000008792    UP000015103    UP000009192    UP000092553    UP000198287   

PRIDE

H9J463    Q4TTE0   

Pfam

PF00575   S1        + More
PF07541   EIF_2_alpha

Interpro

IPR022967   S1_dom        + More
IPR024055   TIF2_asu_C       
IPR003029   S1_domain       
IPR024054   TIF2_asu_middle_sf       
IPR011488   TIF_2_asu       
IPR012340   NA-bd_OB-fold       
IPR000719   Prot_kinase_dom       
IPR011009   Kinase-like_dom_sf       
IPR017441   Protein_kinase_ATP_BS       

SUPFAM

SSF50249   SSF50249        + More
SSF110993   SSF110993       
SSF116742   SSF116742       
SSF56112   SSF56112       

Gene 3D

1.10.150.190     3.30.70.1130    

ProteinModelPortal

H9J463   Q4TTE0   A0A1E1W1Q9   Q8I6Y8   A0A212F2W3   A0A2A4JZF7   + More
A0A0B5KT04   A0A3S2TPR7   S4NQ02   I4DKX1   A0A194Q642   A0A026WVM6   A0A232F0Z6   E2B063   K7J3L3   A0A2A3ESI1   A0A195CPS5   A0A0J7L5Q7   A0A195DVQ2   A0A158NQF0   A0A2J7RGM5   A0A0C9Q3G6   A0A1W4XBW3   A0A151I2D4   E9IDH5   A0A1Y1MEM0   A0A067RES0   A0A195EWA3   A0A1B6HE60   A0A0V0G5V4   A0A2P8Y3G6   A0A069DRN0   A0A023F987   R4WK76   A0A224XS75   R4G619   D6WT44   A0A1B6KMC5   A0A1B6GE77   A0A336LWL3   A0A0A9YLY1   J3JV47   A0A1L8DSF3   A0A2S2RAQ6   A0A1B6CLI4   A0A0K8TNB5   A0A084WCC5   J9K8Z1   A0A2H8TXA5   C4WV63   A0A2S2NND8   A0A1J1HEA7   E0W0E5   A0A2M4BSX9   U5EME2   A0A2M3Z339   A0A2S2NWY1   A0A2M4A4D3   T1DGR1   W5JU13   B0WUX0   A0A1Q3F5I1   A0A182NZI9   A0A182JNF1   A0A182X5J2   A0A182LHQ8   Q7QHH7   A0A182HFW3   A0A182VP07   A0A0P5CUC2   A0A0P5BB66   E9FZ38   A0A182SLN2   A0A182MBR8   A0A182YED0   A0A182IPC7   A0A182WDF1   A0A0P4Z0J6   A0A0P5YB30   A0A182MXJ8   A0A0P5KY04   A0A182H9U0   A0A1S4G076   A0A164TVR0   A0A0P5YAY2   Q16IG9   A0A0P6JSN3   A0A0P6A739   A0A023EPX3   A0A023ES16   A0A0N8DBY6   A0A1D2MG79   A0A182RTG2   A0A0P5UCK6   A0A087U5Q1   B4M340   T1H965   B4L5N5   A0A0M4ENN8   A0A226EY44  

PDB

6O81     E-value=2.67996e-101,     Score=941

KEGG

693063    K03237 translation initiation factor 2 subunit 1 | (RefSeq) eukaryotic translation initiation factor

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)
04140    Autophagy - animal - Bombyx mori (domestic silkworm)
04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0003743   GO:0005851   GO:0043614   GO:0033290   GO:0005850   GO:0043022   GO:0016021   GO:0004672   GO:0005524   GO:0003676   GO:0003723   GO:0005737   GO:0006432   GO:0000049   GO:0000287   GO:0008033   GO:0016787  

PANTHER

PTHR10602  

Length:

332

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01832

Exp number, first 60 AAs:

0.01317

Total prob of N-in:

0.01139

outside

1  -  332

 

 

Pi

231.869385

Theta

193.264249

Tajima's D

0.687851

CLR

0.121894

CSRT

0.573271336433178

Interpretation

Uncertain