Gene

KWMTBOMO12031

Pre Gene Modal

BGIBMGA004312

Annotation

PREDICTED:_sodium-dependent_noradrenaline_transporter_[Bombyx_mori]

Location

Bomo_Chr20(-):6052450-6066290      View in EpiBrowser

Full name

Transporter      

Location in the cell

PlasmaMembrane   Reliability : 4.97

CDS

ATGACTTATTGTTTTGTATTTGTTTCAGACCACAAGCCAACGAAGGGATCTGTCGTAACCTTATCGTGCTACAAAAAAGAGCCTAAAGTACAAATAGAGGAAGAGTATTTTTATACCGAAGGCAGCAAACGACTTAGAGCGAACAGCAAGCCTGAAACATCAGATGGCCGAGAGACATGGGGCACCGGGGCAGACTTCCTTCTGTCCATCATTGGTTTCGCGGTTGATCTGGCCAACGTCTGGAGATTTCCGTATCTTTGCTATAGGAATGGCGGTGGGGCCTTCTTGATACCCTACACTCTGATGCTGGTTTTCGGAGCAGTTCCTCTGTTCTACATGGAGTTGATCCTAGGGCAGTATAACCGACAAGGACCTATCACTCTATGGAAAATATGTCCATTGTTTAAAGGTGTTGGATTCTGCGCAGTCATGGTTGCGTTTTATGTTTCCTTCTATTATAATGTAATAATTGGCTGGGCTTTCTACTTCTTGATGTCGTCAGCTCGATCAGAACTGCCCTGGGTGCATTGCGATAATTCTTGGAACACGGAACAATGTTGGGACTCGGCTCGGTTGAATGGTACCAATCGCACGGATGTTAAATACCAAGGACCACTGTCGCATTTCACGCCCGCTTCAGAATTCTTTCATCGAGCAGTCCTGGAAATGCAGCATTCGGAAGGTTTGAATGATCTAGGTTTGCCGAAATGGCAATTGGCTGCTTGTCTCGGTTTGGTCTATGTAACTTTATACCTTTCATTATTCAAAGGCGTTAAAAGCTCCGGAAAAGTGGTATGGATGACAGCAACAATGCCGTACGTTGTCCTGTCGATCCTCCTGGCCCGTGGATTACTTCTGCCGGGAGCAACACGGGGCATCGCCTACTATTTGCAGCCGGAACTTACTAGGCTCAAGGATACGCAGGTTTGGGTGGATGCAGCGGTGCAGATATTTTATTCCGTTGGTGCTGGTTTCGGCGTTCATCTTTCATATGCAAGTTACAACACTTTTCACAACAATTGCTACAGGGATTGCTTGGTTACAACTCTAGTGAATTGTTTCACGTCATTCTTCTCCGGGTTCGTGATCTTCACGTACCTCGGGTTCATGTCGTACAAACAGGGTGTACCCATTTCCTCCGTGGCTACTGAAGGACCAGGATTGGTATTCCAAGTATACCCCGAGGCTGTTGCTACTCTACCGGGGGCGAGCTTATGGGCGATGTTGTTCTTCTTTATGCTGATCATGCTTGGACTGGACTCGGGGATGGGTGGTCTCGAGTGTGTGATCACCGGTCTTTTGGACCAGGCGCGTGCGAGCGGTGCACACTGGCTCCGCCGGGAGCACTTCACGCTGCTGGTCGTCTGTGTGTCCTTCTGTATCGCTTGCATCAATGTAACACCGGGTGGAATTTACATGTTTCATCTTTTGGACACCTACGCTGCCGGCATATCACTGTTGTGCTCGGCGTTGTTCGAAGCCGTTGCTGTCTCGTGGTTTTATGGTCTGAAAAGGTTCTCTGACGATGTTGAAGAAATGCTCGGCTTCAGGCCCGGTATTTACTGGAGGATATGCTGGAAATTTGTCAGCCCAATATTCATTATCGGAGTAGTAGTTTTCGGCTTATTGTACCAGCAGCCTCTTCAGTATCAGCAATACACGTATCCGCAGTGGGCCGTGGTGTTGGGCTGGGGTCTGGCCTGCTCCTCCATATTAATGATACCTATCGTAGCTATATACAAACTGGCCACAACTCCCGGAACATTTAGACAGCGTCTTGCTTGCTGCATTTCTCCTGAATCCGAACACGAAGCCATCCGAGGTGGGGCTCCCGTCAGTCGCTTCACGTGGCGACATTGGTTATATGTATAA

Protein

MTYCFVFVSDHKPTKGSVVTLSCYKKEPKVQIEEEYFYTEGSKRLRANSKPETSDGRETWGTGADFLLSIIGFAVDLANVWRFPYLCYRNGGGAFLIPYTLMLVFGAVPLFYMELILGQYNRQGPITLWKICPLFKGVGFCAVMVAFYVSFYYNVIIGWAFYFLMSSARSELPWVHCDNSWNTEQCWDSARLNGTNRTDVKYQGPLSHFTPASEFFHRAVLEMQHSEGLNDLGLPKWQLAACLGLVYVTLYLSLFKGVKSSGKVVWMTATMPYVVLSILLARGLLLPGATRGIAYYLQPELTRLKDTQVWVDAAVQIFYSVGAGFGVHLSYASYNTFHNNCYRDCLVTTLVNCFTSFFSGFVIFTYLGFMSYKQGVPISSVATEGPGLVFQVYPEAVATLPGASLWAMLFFFMLIMLGLDSGMGGLECVITGLLDQARASGAHWLRREHFTLLVVCVSFCIACINVTPGGIYMFHLLDTYAAGISLLCSALFEAVAVSWFYGLKRFSDDVEEMLGFRPGIYWRICWKFVSPIFIIGVVVFGLLYQQPLQYQQYTYPQWAVVLGWGLACSSILMIPIVAIYKLATTPGTFRQRLACCISPESEHEAIRGGAPVSRFTWRHWLYV

Similarity

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.

Feature

chain  Transporter

Uniprot

A0A2A4JW50   Q95VZ4   A0A0G3VI17   A0A194QBN1   Q4F9L7   Q4F9L6   + More
A0A2H1W3A0   A0A194QQ95   A0A3S2NWE8   A0A212EYB8   H9J473   A0A139WF45   A0A1Y1N0B0   E0VII8   A0A1B6D9T1   A0A067RBN9   A0A224X8S8   A0A023F4G2   A0A2S2RAM0   J9K6Y9   A0A2R5LNN7   A0A147BMK7   T1I6U4   A0A0A9YIP2   U5TBR5   T1J4W0   A0A087T891   U5TBH5   U5T862   B7PMD1   A0A0P4VPR8   A0A0K2USJ4   N6TG93   A0A1S3KVY3   A0A3Q3F619   H2TS08   A0A3P8SMA2   A0A3P8X986   A0A3Q1H5J6   A0A3B4D3D5   A0A3Q1FP96   A0A2U9BD53   A0A3B5AC26   A0A3B4XWP2   W5MR30   W5MR40   G3PWI5   W5KZP3   A0A3P9NHC8   A0A2D0Q645   M4A086   A0A3Q3JGI9   A0A3B3C9X3   A0A3P8XDM8   A0A3B5M1M2   A0A087YE66   A0A3B3X744   A0A146WF78   A0A346RQW8   A0A3P8VBY7   A0A3Q2ED20   A0A1W5ARW5   A0A3B5QMW5   A0A1W5AZG2   A0A3P8V979   A0A1S3IWS7   A0A1L8GE72   A0A3B4C769   F1R3H6   A0A1S3IUX5   W5MJG9   Q90ZV1   A0A2D0S039   A0A3P8XMW3   O42482   R7TSR3   A0A1V4K1V4   A0A3N0XEX3   A0A3B3Q7S6   A0A3Q3B0W7   A0A3B4BBD3   A0A3L8SFH6   A0A3B3R8U0   A0A0Q3TJY1   Q0PKT4   A0A218UYJ4   G1MYP0   A0A2Y9DSN1   H2TS03   A0A315W074   G3WUU1   A0A1A7XVR8   A0A1L8FS41   K7GFU5   A0A0P7VIU1   A0A2I0M7Y9   F7FWA1   H0ZAC2   A0A3P9JNY7  

Pubmed

11804806    26354079    15986385    22118469    19121390    18362917    + More
19820115    28004739    20566863    24845553    25474469    29652888    25401762    17142674    23537049    21551351    25069045    25329095    23542700    29451363    30120603    24487278    27762356    23594743    11231083    9092590    23254933    29240929    25463417    30282656    20838655    29703783    21709235    17381049    23371554    17495919    20360741    17554307   

EMBL

NWSH01000515    PCG75918.1    AF388173    AAL09578.2    KP657645    AKL78870.1    + More
KQ459460    KPJ00846.1    DQ097796    AAZ08592.2    DQ097797    AAZ08593.2    ODYU01005982    SOQ47426.1    KQ461181    KPJ07672.1    RSAL01000132    RVE46344.1    AGBW02011555    OWR46493.1    BABH01032501    KQ971354    KYB26417.1    GEZM01016170    JAV91351.1    DS235200    EEB13194.1    GEDC01028669    GEDC01014839    JAS08629.1    JAS22459.1    KK852611    KDR20283.1    GFTR01007659    JAW08767.1    GBBI01002650    JAC16062.1    GGMS01017893    MBY87096.1    ABLF02030771    GGLE01006912    MBY11038.1    GEGO01003692    JAR91712.1    ACPB03005112    GBHO01014204    JAG29400.1    KF321729    AGY96957.1    JH431850    KK113908    KFM61330.1    KF321730    AGY96958.1    KF321731    AGY96959.1    ABJB010134719    ABJB010470067    ABJB010499826    ABJB010927746    ABJB011106229    DS746704    EEC07753.1    GDRN01108184    JAI57300.1    HACA01023888    CDW41249.1    APGK01028545    KB740694    ENN79419.1    CP026247    AWP01893.1    AHAT01020181    AHAT01020182    AHAT01020183    AYCK01004742    GCES01057633    GCES01013368    JAR28690.1    MH085049    AXS75745.1    CM004473    OCT82188.1    BX663609    AHAT01020906    AF318177    AAK52449.1    U72877    AAB67676.1    AMQN01000284    KB308724    ELT96928.1    LSYS01005191    OPJ77867.1    RJVU01077109    ROI15904.1    QUSF01000023    RLW01230.1    LMAW01002501    KQK80910.1    DQ813341    ABG91820.1    MUZQ01000095    OWK58581.1    NHOQ01000682    PWA29135.1    AEFK01053212    AEFK01053213    AEFK01053214    AEFK01053215    AEFK01053216    AEFK01053217    AEFK01053218    AEFK01053219    HADW01020475    HADX01008531    SBP21875.1    CM004477    OCT74385.1    AGCU01072366    AGCU01072367    AGCU01072368    AGCU01072369    AGCU01072370    JARO02001429    KPP75498.1    AKCR02000031    PKK25798.1    ABQF01035888    ABQF01035889    ABQF01035890    ABQF01035891   

Proteomes

UP000218220    UP000053268    UP000053240    UP000283053    UP000007151    UP000005204    + More
UP000007266    UP000009046    UP000027135    UP000007819    UP000015103    UP000054359    UP000001555    UP000019118    UP000087266    UP000261660    UP000005226    UP000265080    UP000265140    UP000265040    UP000261440    UP000257200    UP000246464    UP000261400    UP000261360    UP000018468    UP000007635    UP000018467    UP000242638    UP000221080    UP000002852    UP000261600    UP000261560    UP000261380    UP000028760    UP000261480    UP000265000    UP000265120    UP000265020    UP000192224    UP000085678    UP000186698    UP000000437    UP000014760    UP000190648    UP000261540    UP000264800    UP000261520    UP000276834    UP000051836    UP000197619    UP000001645    UP000248480    UP000007648    UP000007267    UP000034805    UP000053872    UP000002280    UP000007754    UP000265200   

PRIDE

H9J473    Q0PKT4   

Pfam

PF00209   SNF        + More
PF09068   EF-hand_2
PF09069   EF-hand_3
PF00569   ZZ
PF00246   Peptidase_M14
PF02244   Propep_M14
PF13499   EF-hand_7
PF13202   EF-hand_5
PF01553   Acyltransferase

Interpro

IPR037272   SNS_sf        + More
IPR000175   Na/ntran_symport       
IPR015153   EF-hand_dom_typ1       
IPR015154   EF-hand_dom_typ2       
IPR011992   EF-hand-dom_pair       
IPR000433   Znf_ZZ       
IPR003146   M14A_act_pep       
IPR036990   M14A-like_propep       
IPR000834   Peptidase_M14       
IPR034223   IGCP-like_CPD       
IPR002123   Plipid/glycerol_acylTrfase       
IPR002048   EF_hand_dom       
IPR018247   EF_Hand_1_Ca_BS       
IPR002436   Na/ntran_symport_dopamine       
IPR002435   Na/ntran_symport_noradrenaline       

SUPFAM

SSF161070   SSF161070        + More
SSF47473   SSF47473       

Gene 3D

3.30.70.340    

CDD

cd03860  M14_CP_A-B_like
cd00051  EFh

ProteinModelPortal

A0A2A4JW50   Q95VZ4   A0A0G3VI17   A0A194QBN1   Q4F9L7   Q4F9L6   + More
A0A2H1W3A0   A0A194QQ95   A0A3S2NWE8   A0A212EYB8   H9J473   A0A139WF45   A0A1Y1N0B0   E0VII8   A0A1B6D9T1   A0A067RBN9   A0A224X8S8   A0A023F4G2   A0A2S2RAM0   J9K6Y9   A0A2R5LNN7   A0A147BMK7   T1I6U4   A0A0A9YIP2   U5TBR5   T1J4W0   A0A087T891   U5TBH5   U5T862   B7PMD1   A0A0P4VPR8   A0A0K2USJ4   N6TG93   A0A1S3KVY3   A0A3Q3F619   H2TS08   A0A3P8SMA2   A0A3P8X986   A0A3Q1H5J6   A0A3B4D3D5   A0A3Q1FP96   A0A2U9BD53   A0A3B5AC26   A0A3B4XWP2   W5MR30   W5MR40   G3PWI5   W5KZP3   A0A3P9NHC8   A0A2D0Q645   M4A086   A0A3Q3JGI9   A0A3B3C9X3   A0A3P8XDM8   A0A3B5M1M2   A0A087YE66   A0A3B3X744   A0A146WF78   A0A346RQW8   A0A3P8VBY7   A0A3Q2ED20   A0A1W5ARW5   A0A3B5QMW5   A0A1W5AZG2   A0A3P8V979   A0A1S3IWS7   A0A1L8GE72   A0A3B4C769   F1R3H6   A0A1S3IUX5   W5MJG9   Q90ZV1   A0A2D0S039   A0A3P8XMW3   O42482   R7TSR3   A0A1V4K1V4   A0A3N0XEX3   A0A3B3Q7S6   A0A3Q3B0W7   A0A3B4BBD3   A0A3L8SFH6   A0A3B3R8U0   A0A0Q3TJY1   Q0PKT4   A0A218UYJ4   G1MYP0   A0A2Y9DSN1   H2TS03   A0A315W074   G3WUU1   A0A1A7XVR8   A0A1L8FS41   K7GFU5   A0A0P7VIU1   A0A2I0M7Y9   F7FWA1   H0ZAC2   A0A3P9JNY7  

PDB

4XPA     E-value=9.02863e-160,     Score=1448

KEGG

100127051    K05035 solute carrier family 6 (neurotransmitter transporter, noradrenalin) member 2 | (RefSeq) Oat;

GO

GO:0005328   GO:0016021   GO:0008270   GO:0015293   GO:0005330   GO:0035240   GO:0009986   GO:0030424   GO:0043005   GO:0005886   GO:0004181   GO:0005509   GO:0016746   GO:0005887   GO:0032809   GO:0051583   GO:0042734   GO:0015874   GO:0005334   GO:0048265   GO:0008504   GO:0098810   GO:0003779   GO:0098793   GO:0042053   GO:0007626   GO:0043025   GO:0042416   GO:0042220   GO:0021984   GO:0007595   GO:0060134   GO:0047485   GO:0040018   GO:0016600   GO:0001504   GO:0042420   GO:0007608   GO:0006836   GO:0022891   GO:0005856   GO:0004890   GO:0005216   GO:0043564   GO:0006418   GO:0003824  

PANTHER

PTHR11616  

Length:

623

Number of predicted TMHs:

12

Exp number of AAs in TMHs:

260.59724

Exp number, first 60 AAs:

0.36023

Total prob of N-in:

0.71133

inside

1  -  65

TMhelix

66  -  85

outside

86  -  94

TMhelix

95  -  117

inside

118  -  137

TMhelix

138  -  160

outside

161  -  236

TMhelix

237  -  255

inside

256  -  263

TMhelix

264  -  286

outside

287  -  314

TMhelix

315  -  337

inside

338  -  349

TMhelix

350  -  372

outside

373  -  396

TMhelix

397  -  419

inside

420  -  448

TMhelix

449  -  471

outside

472  -  480

TMhelix

481  -  503

inside

504  -  523

TMhelix

524  -  543

outside

544  -  557

TMhelix

558  -  580

inside

581  -  623

 

 

Pi

233.908139

Theta

191.023341

Tajima's D

0.9982

CLR

0.456477

CSRT

0.654317284135793

Interpretation

Uncertain