Gene

KWMTBOMO12026

Annotation

PREDICTED:_probable_splicing_factor_3B_subunit_5_[Amyelois_transitella]

Location

Bomo_Chr20(-):5942588-5943200      View in EpiBrowser

Full name

Splicing factor 3B subunit 5      

Alternative Name

Pre-mRNA-splicing factor SF3b 10 kDa subunit

Location in the cell

Nuclear   Reliability : 2.003

CDS

ATGGGTGAAAGATACAACATTCACAGTCAACTTGAACATCTACAGAGCAAATATATAGGCACAGGCCACGCCGACACTACAAAATATGAATGGCTTATGAACCAACATCGCGACTCTTGCTGCAGTTACATGGGTCATCCGGATTTGTTGAGTTACTTTGCGATCGTAGAAAATGAATCTAAAGCGCGCGTAAAATTCAATTTGATGGAACGAATGCTTCAACCATGCGGCCCACCGCCAGAAAAGCCTGAAGATTAA

Protein

MGERYNIHSQLEHLQSKYIGTGHADTTKYEWLMNQHRDSCCSYMGHPDLLSYFAIVENESKARVKFNLMERMLQPCGPPPEKPED

Description

Involved in pre-mRNA splicing as component of spliceosome (PubMed:27185460, PubMed:18981222). As part of the spliceosome complex, plays a role in the regulation of spermatogonial differentiation (PubMed:27035939). When associated with the SAGA transcription regulatory histone acetylation (HAT) complex, might be involved in the transcriptional activation of a subset of SAGA-regulated genes (PubMed:27185460).

Subunit

Component of the spliceosome B complex.
Component of the SF3B complex (PubMed:27185460, PubMed:18981222). SF3B complex associates with the splicing factor SF3A complex and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex (U2 snRNP)(PubMed:27185460, PubMed:18981222). Identified in the SAGA transcription regulatory histone acetylation (HAT) complex; the interaction is RNA-independent (PubMed:27185460).

Similarity

Belongs to the SF3B5 family.

Keywords

Complete proteome   mRNA processing   mRNA splicing   Nucleus   Reference proteome   Spliceosome  

Feature

chain  Splicing factor 3B subunit 5

Uniprot

A0A2W1BM23   A0A2H1V217   A0A212FFA1   A0A212EZ63   A0A194QQ96   A0A194QBN6   + More
S4PMD5   A0A0L7KN54   A0A1W4XTI7   A0A088AQ08   A0A151IIA0   A0A154PJE7   A0A0L7QLT6   F4WZT0   A0A2A3EI78   V9IMM7   A0A0N0U3G3   E2BD84   A0A026X2V0   A0A158NGV9   K1QWJ4   E2AM09   A0A0J7L5P8   K7IM74   A0A232FLU3   B4NA69   E0W0G6   U5EVQ4   Q4QPR9   A0A1W4VQN2   B4QXB2   A0A1B2AKC8   B4PTZ2   B4HKI9   B3P1U6   Q9VHI4   B4M456   B4KBU5   B4JFR7   N6U441   A0A2J7PE65   A0A067RES4   A0A2P8XD64   A0A084WIL7   A0A182N2V0   A0A3B0JDL0   B5DIX0   B4GPT7   V5FYK0   A0A2M3Z9D4   A0A2M4ATE9   A0A2M4C4Z6   W5JWS3   A0A182FB58   Q175C9   A0A023EE68   A0A182WDZ2   A0A0M4ERH0   B3M203   A0A182PP21   A0A182XJT3   Q7PZH2   A0A182HHK0   A0A0N7Z8U9   A0A224XYW2   A0A1Q3FBT0   B0XFY1   A0A182RVI7   T1I4A4   S4S1D5   A0A0V0GBM7   A0A210PHE9   A0A182JRW8   A0A3N0YTJ8   A0A3B4DEW1   A0A170UYM7   A0A0P7TRX7   T1JMA3   A0A2D0QJD7   A0A3B3RU00   A0A1W4ZWM6   Q6ZM78   A0A224Z955   A0A131YEP0   L7M2A8   A0A131XES4   G3MN88   A0A023GGV4   A0A3S3PAI6   A0A0K8TRJ6   A0A3B3DER4   H2LJK8   A0A3P9JJ73   A0A3B4EWT0   A0A3Q3CMY9   A0A3Q4MSZ6   A0A3Q0RJ28   I3KY34   A0A3P8QVF4   A0A3P9DUA0  

Pubmed

28756777    22118469    26354079    23622113    26227816    21719571    + More
20798317    24508170    30249741    21347285    22992520    20075255    28648823    17994087    20566863    17550304    10731132    12537572    18981222    27185460    27035939    23537049    24845553    29403074    24438588    15632085    20920257    23761445    17510324    24945155    26483478    12364791    14747013    17210077    27129103    28812685    29240929    15256591    23594743    28797301    26830274    25576852    28049606    22216098    26369729    29451363    17554307    25186727   

EMBL

KZ150034    PZC74664.1    ODYU01000321    SOQ34859.1    AGBW02008841    OWR52411.1    + More
AGBW02011364    OWR46783.1    KQ461181    KPJ07677.1    KQ459460    KPJ00851.1    GAIX01003615    JAA88945.1    JTDY01008476    KOB64550.1    KQ977492    KYN02308.1    KQ434936    KZC11933.1    KQ414905    KOC59613.1    GL888480    EGI60355.1    KZ288232    PBC31503.1    JR053423    AEY61926.1    KQ435922    KOX68671.1    GL447585    EFN86312.1    KK107020    QOIP01000004    EZA62428.1    RLU23546.1    JH818934    EKC41277.1    GL440703    EFN65529.1    LBMM01000653    KMQ97873.1    NNAY01000049    OXU31553.1    CH964232    EDW80712.1    DS235858    EEB19122.1    GANO01000915    JAB58956.1    BT023697    AAY85097.1    CM000364    EDX13683.1    KX531805    ANY27615.1    CM000160    EDW96603.1    CH480815    EDW42939.1    CH954181    EDV49834.1    AE014297    CH940652    EDW59417.1    CH933806    EDW15797.1    CH916369    EDV93548.1    APGK01050200    KB741168    KB632313    ENN73357.1    ERL92162.1    NEVH01026110    PNF14602.1    KK852513    KDR22262.1    PYGN01002827    PSN29923.1    ATLV01023937    KE525347    KFB50061.1    OUUW01000005    SPP80175.1    CH379060    EDY70263.1    CH479187    EDW39609.1    GALX01005711    JAB62755.1    GGFM01004349    MBW25100.1    GGFK01010671    MBW43992.1    GGFJ01011233    MBW60374.1    ADMH02000120    ETN67735.1    CH477402    EAT41692.1    JXUM01088891    GAPW01006674    KQ563731    JAC06924.1    KXJ73414.1    CP012526    ALC47110.1    ALC47111.1    CH902617    EDV43327.1    AAAB01008986    EAA00185.4    APCN01002419    GDKW01002339    JAI54256.1    GFTR01001218    JAW15208.1    GFDL01010038    JAV25007.1    DS232970    EDS27100.1    ACPB03017457    GECL01000744    JAP05380.1    NEDP02076697    OWF35910.1    RJVU01026577    ROL49533.1    GEMB01007173    JAR96196.1    JARO02010704    KPP60479.1    JH431939    AL772289    BC076334    AY648771    AAH76334.1    AAT68089.1    GFPF01012028    MAA23174.1    GEDV01010763    JAP77794.1    GACK01006573    JAA58461.1    GEFH01003876    JAP64705.1    JO843339    JO843341    AEO34956.1    GBBM01003208    GBBM01003207    GBBM01003206    GBBM01003205    JAC32213.1    NCKU01002878    RWS08627.1    GDAI01000840    JAI16763.1    AERX01001534   

Proteomes

UP000007151    UP000053240    UP000053268    UP000037510    UP000192223    UP000005203    + More
UP000078542    UP000076502    UP000053825    UP000007755    UP000242457    UP000053105    UP000008237    UP000053097    UP000279307    UP000005205    UP000005408    UP000000311    UP000036403    UP000002358    UP000215335    UP000007798    UP000009046    UP000192221    UP000000304    UP000002282    UP000001292    UP000008711    UP000000803    UP000008792    UP000009192    UP000001070    UP000019118    UP000030742    UP000235965    UP000027135    UP000245037    UP000030765    UP000075884    UP000268350    UP000001819    UP000008744    UP000000673    UP000069272    UP000008820    UP000069940    UP000249989    UP000075920    UP000092553    UP000007801    UP000075885    UP000076407    UP000007062    UP000075840    UP000002320    UP000075900    UP000015103    UP000245300    UP000242188    UP000075881    UP000261440    UP000034805    UP000221080    UP000261540    UP000192224    UP000000437    UP000285301    UP000261560    UP000001038    UP000265180    UP000265200    UP000261460    UP000264840    UP000261580    UP000261340    UP000005207    UP000265100    UP000265160   

PRIDE

Q4QPR9    Q9VHI4   

Pfam

PF07189   SF3b10

Interpro

IPR017089   Splicing_factor_3B_subunit_5        + More
IPR009846   SF3b5/RDS3-10       

ProteinModelPortal

A0A2W1BM23   A0A2H1V217   A0A212FFA1   A0A212EZ63   A0A194QQ96   A0A194QBN6   + More
S4PMD5   A0A0L7KN54   A0A1W4XTI7   A0A088AQ08   A0A151IIA0   A0A154PJE7   A0A0L7QLT6   F4WZT0   A0A2A3EI78   V9IMM7   A0A0N0U3G3   E2BD84   A0A026X2V0   A0A158NGV9   K1QWJ4   E2AM09   A0A0J7L5P8   K7IM74   A0A232FLU3   B4NA69   E0W0G6   U5EVQ4   Q4QPR9   A0A1W4VQN2   B4QXB2   A0A1B2AKC8   B4PTZ2   B4HKI9   B3P1U6   Q9VHI4   B4M456   B4KBU5   B4JFR7   N6U441   A0A2J7PE65   A0A067RES4   A0A2P8XD64   A0A084WIL7   A0A182N2V0   A0A3B0JDL0   B5DIX0   B4GPT7   V5FYK0   A0A2M3Z9D4   A0A2M4ATE9   A0A2M4C4Z6   W5JWS3   A0A182FB58   Q175C9   A0A023EE68   A0A182WDZ2   A0A0M4ERH0   B3M203   A0A182PP21   A0A182XJT3   Q7PZH2   A0A182HHK0   A0A0N7Z8U9   A0A224XYW2   A0A1Q3FBT0   B0XFY1   A0A182RVI7   T1I4A4   S4S1D5   A0A0V0GBM7   A0A210PHE9   A0A182JRW8   A0A3N0YTJ8   A0A3B4DEW1   A0A170UYM7   A0A0P7TRX7   T1JMA3   A0A2D0QJD7   A0A3B3RU00   A0A1W4ZWM6   Q6ZM78   A0A224Z955   A0A131YEP0   L7M2A8   A0A131XES4   G3MN88   A0A023GGV4   A0A3S3PAI6   A0A0K8TRJ6   A0A3B3DER4   H2LJK8   A0A3P9JJ73   A0A3B4EWT0   A0A3Q3CMY9   A0A3Q4MSZ6   A0A3Q0RJ28   I3KY34   A0A3P8QVF4   A0A3P9DUA0  

PDB

6QX9     E-value=1.86223e-36,     Score=375

KEGG

101736232    K12832 splicing factor 3B subunit 5 | (RefSeq) probable splicing factor 3B subunit 5

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0000398   GO:0005686   GO:0071011   GO:0016021   GO:0010468   GO:0007283   GO:0000124   GO:0003723  

PANTHER

PTHR20978  

Subcellular location

Nucleus  

Length:

85

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00373

Exp number, first 60 AAs:

0.00373

Total prob of N-in:

0.45597

outside

1  -  85

 

 

Pi

301.39466

Theta

176.659268

Tajima's D

2.221345

CLR

0

CSRT

0.913804309784511

Interpretation

Uncertain