Gene

KWMTBOMO12012

Pre Gene Modal

BGIBMGA004358

Annotation

PREDICTED:_focal_adhesion_kinase_1_[Bombyx_mori]

Location

Bomo_Chr20(-):5434517-5443740      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 2.182 Nuclear   Reliability : 1.875

CDS

ATGCAGCCCGCTCCGACGGGCGGCTCGCCCAAGCGACATGCACCCATTCAGACGCACGGCGCTGTAGCGGATCAGTCGACCTTGAAGGTGCATCTGCCGAATGGCGGCTTCAATCTGGTGCGAGCCTCGCCTGATGAAGACGTGAGGTCGGTGCTGCGACTCGTTGCCTCGAGATTAGCCTCAGGAGAGAGGGTCTACGCGTCCTGTTTTGCTTTACGAGCGAGACTCTCAAACGGGAAGATCCGATGGATTCATCAGGACACTCCCGTTTCGGAGTTGTTGACGAAGTGGCCGGCCAGCGAGTGGCGGCTCGAGCTACGAGTACGGTACCTGCCCGCGAACCTCAGGGAGCTCTGCGAAGCCGATCGCGTTACCTTCCACTATTATTACGATCAGGTGCGACACGAATACCTCAATGCCAATCATCCTACCGTAGACCAGGAGCTGGCCGTGCAAATATGTTGTTTAGAAATTAAGTACTTTTGTAAAGACATGCAGATCTCTATGGACAAAAAGTCGAACATCGAATATCTGGAGAAGGAGTTCGGCCTGCACAAGTGCTGA

Protein

MQPAPTGGSPKRHAPIQTHGAVADQSTLKVHLPNGGFNLVRASPDEDVRSVLRLVASRLASGERVYASCFALRARLSNGKIRWIHQDTPVSELLTKWPASEWRLELRVRYLPANLRELCEADRVTFHYYYDQVRHEYLNANHPTVDQELAVQICCLEIKYFCKDMQISMDKKSNIEYLEKEFGLHKC

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Uniprot

A0A212FAB3   A0A2A4IZB3   A0A2H1VD97   A0A194QQA5   A0A194QFF4   A0A2W1BP60   + More
A0A2J7RP41   A0A0C9Q9I1   A0A0C9R9H6   A0A2J7RP27   A0A0C9RQQ4   A0A2J7RP39   A0A0C9RR47   A0A067R8A5   A0A1Y1N9J7   A0A1Y1N5U9   A0A1Y1N5Z8   A0A232EXM7   A0A195FUN6   A0A158NYB0   A0A151IX42   A0A151WIK7   E9JCV7   A0A0J7LAY4   E2AKA8   A0A026W508   A0A3L8DXL9   A0A0L7RDW5   A0A088AN13   A0A2A3EE32   A0A154PBB2   A0A310SHX3   A0A0M8ZYC2   A0A0L7LV20   A0A1B6DTP2   A0A1B6LGV8   A0A1B6LWH8   A0A1B6D3T2   A0A1B6E257   A0A1B6DL08   E2BTJ2   A0A139WEU8   D6WQS4   A0A0T6BD26   A0A1B6IZC4   A0A2G8LI83   A0A1S3GYK4   A0A1B6GEL6   V3ZMB0   T1IYC0   A0A2C9JHX6   A0A2C9JHV3   A0A2C9JHV5   A0A2C9JHW3   A0A2C9JHV8   A0A2C9JHW6   A0A2T7NP87   A0A226F2U6   A0A0B7BAE7   A0A0B7B9S0   A0A0B7B9S6   A0A2S2Q285   K1PKI5   J9JPR2   Q7Z1D3   W4YV37   T1E1S3   A0A210R109   U4U150   C3Y1A6   R7TYU7   A0A2P6KVD9   A0A1D1VCM1   N6TQ25   A0A224YYY1   A0A3R7M2I2   A0A1L8DKY7   A0A1L8DL69   A0A0L8GYB8   A0A0L8GY73   A0A131YUV2   A0A131YWN0   B9UPG7   L7MI74   A0A2R5LIB2   A0A293MH51   A0A293LJS2   A0A0P4VHC4   A0A1V9XHT5   T1I867   A0A0V0G5T5   A0A069DZP2   A0A224X6E0   A0A0A9XYV5   A0A0K8SAY9   A0A0K8S9G3  

Pubmed

22118469    26354079    28756777    24845553    28004739    28648823    + More
21347285    21282665    20798317    24508170    30249741    26227816    18362917    19820115    29023486    23254933    15562597    22992520    12925747    15161103    28812685    23537049    18563158    27649274    28797301    26830274    19013481    25576852    27129103    28327890    26334808    25401762   

EMBL

AGBW02009503    OWR50672.1    NWSH01004533    PCG64979.1    ODYU01001925    SOQ38808.1    + More
KQ461181    KPJ07688.1    KQ459053    KPJ04144.1    KZ150043    PZC74530.1    NEVH01002141    PNF42593.1    GBYB01011033    JAG80800.1    GBYB01009577    JAG79344.1    PNF42590.1    GBYB01009576    JAG79343.1    PNF42592.1    GBYB01011020    JAG80787.1    KK852816    KDR15787.1    GEZM01011987    GEZM01011985    JAV93315.1    GEZM01011988    JAV93312.1    GEZM01011986    JAV93314.1    NNAY01001731    OXU23095.1    KQ981261    KYN44163.1    ADTU01003596    ADTU01003597    ADTU01003598    ADTU01003599    ADTU01003600    ADTU01003601    ADTU01003602    ADTU01003603    ADTU01003604    ADTU01003605    KQ980834    KYN12384.1    KQ983089    KYQ47664.1    GL771866    EFZ09187.1    LBMM01000095    KMR04988.1    GL440210    EFN66133.1    KK107419    EZA51098.1    QOIP01000003    RLU24689.1    KQ414613    KOC69043.1    KZ288269    PBC30043.1    KQ434864    KZC09131.1    KQ759870    OAD62388.1    KQ435824    KOX72079.1    JTDY01000033    KOB79285.1    GEDC01008289    JAS29009.1    GEBQ01017109    JAT22868.1    GEBQ01011951    JAT28026.1    GEDC01016954    JAS20344.1    GEDC01005309    JAS31989.1    GEDC01010922    JAS26376.1    GL450410    EFN81020.1    KQ971354    KYB26419.1    EFA06030.2    LJIG01001741    KRT85199.1    GECU01015433    JAS92273.1    MRZV01000069    PIK59964.1    GECZ01008909    JAS60860.1    KB202050    ESO92503.1    JH431679    PZQS01000010    PVD22981.1    LNIX01000001    OXA63808.1    HACG01042167    HACG01042168    HACG01042170    CEK89032.1    CEK89033.1    CEK89035.1    HACG01042164    HACG01042166    CEK89029.1    CEK89031.1    HACG01042165    HACG01042169    HACG01042171    CEK89030.1    CEK89034.1    CEK89036.1    GGMS01002672    MBY71875.1    JH818685    EKC24552.1    ABLF02029484    AY144487    AAN38839.1    AAGJ04170363    AAGJ04170364    AAGJ04170365    AAGJ04170366    AAGJ04170367    AAGJ04170368    AAGJ04170369    AAGJ04170370    AAGJ04170371    AAGJ04170372    GAKT01000030    JAA93032.1    NEDP02000979    OWF54581.1    KB631982    ERL87594.1    GG666480    EEN65646.1    AMQN01001956    KB307198    ELT99103.1    MWRG01004713    PRD30297.1    BDGG01000004    GAU98565.1    APGK01025701    KB740600    ENN80113.1    GFPF01007824    MAA18970.1    QCYY01002485    ROT69985.1    GFDF01007047    JAV07037.1    GFDF01006994    JAV07090.1    KQ419936    KOF81917.1    KOF81918.1    GEDV01006235    JAP82322.1    GEDV01006236    JAP82321.1    EU927416    ACL14651.1    GACK01002061    JAA62973.1    GGLE01005147    MBY09273.1    GFWV01020299    MAA45027.1    GFWV01008998    MAA33727.1    GDKW01002760    JAI53835.1    MNPL01010758    OQR72953.1    ACPB03011989    ACPB03011990    GECL01003076    JAP03048.1    GBGD01000295    JAC88594.1    GFTR01008410    JAW08016.1    GBHO01019567    GBHO01019566    GBHO01019565    JAG24037.1    JAG24038.1    JAG24039.1    GBRD01015906    JAG49920.1    GBRD01015905    JAG49921.1   

Proteomes

UP000007151    UP000218220    UP000053240    UP000053268    UP000235965    UP000027135    + More
UP000215335    UP000078541    UP000005205    UP000078492    UP000075809    UP000036403    UP000000311    UP000053097    UP000279307    UP000053825    UP000005203    UP000242457    UP000076502    UP000053105    UP000037510    UP000008237    UP000007266    UP000230750    UP000085678    UP000030746    UP000076420    UP000245119    UP000198287    UP000005408    UP000007819    UP000007110    UP000242188    UP000030742    UP000001554    UP000014760    UP000186922    UP000019118    UP000283509    UP000053454    UP000192247    UP000015103   

Pfam

PF00373   FERM_M        + More
PF07714   Pkinase_Tyr
PF03623   Focal_AT
PF18038   FERM_N_2

Interpro

IPR001245   Ser-Thr/Tyr_kinase_cat_dom        + More
IPR000299   FERM_domain       
IPR029071   Ubiquitin-like_domsf       
IPR011009   Kinase-like_dom_sf       
IPR019748   FERM_central       
IPR011993   PH-like_dom_sf       
IPR041390   FADK_N       
IPR035963   FERM_2       
IPR041784   FAK1/PYK2_FERM_C       
IPR008266   Tyr_kinase_AS       
IPR020635   Tyr_kinase_cat_dom       
IPR005189   Focal_adhesion_kin_target_dom       
IPR036137   Focal_adhe_kin_target_dom_sf       
IPR019749   Band_41_domain       
IPR000719   Prot_kinase_dom       
IPR014352   FERM/acyl-CoA-bd_prot_sf       
IPR017441   Protein_kinase_ATP_BS       
IPR001412   aa-tRNA-synth_I_CS       

SUPFAM

SSF56112   SSF56112        + More
SSF68993   SSF68993       
SSF54236   SSF54236       
SSF47031   SSF47031       

Gene 3D

1.20.80.10     2.30.29.30    

CDD

cd13190  FERM_C_FAK1
cd14473  FERM_B-lobe

ProteinModelPortal

A0A212FAB3   A0A2A4IZB3   A0A2H1VD97   A0A194QQA5   A0A194QFF4   A0A2W1BP60   + More
A0A2J7RP41   A0A0C9Q9I1   A0A0C9R9H6   A0A2J7RP27   A0A0C9RQQ4   A0A2J7RP39   A0A0C9RR47   A0A067R8A5   A0A1Y1N9J7   A0A1Y1N5U9   A0A1Y1N5Z8   A0A232EXM7   A0A195FUN6   A0A158NYB0   A0A151IX42   A0A151WIK7   E9JCV7   A0A0J7LAY4   E2AKA8   A0A026W508   A0A3L8DXL9   A0A0L7RDW5   A0A088AN13   A0A2A3EE32   A0A154PBB2   A0A310SHX3   A0A0M8ZYC2   A0A0L7LV20   A0A1B6DTP2   A0A1B6LGV8   A0A1B6LWH8   A0A1B6D3T2   A0A1B6E257   A0A1B6DL08   E2BTJ2   A0A139WEU8   D6WQS4   A0A0T6BD26   A0A1B6IZC4   A0A2G8LI83   A0A1S3GYK4   A0A1B6GEL6   V3ZMB0   T1IYC0   A0A2C9JHX6   A0A2C9JHV3   A0A2C9JHV5   A0A2C9JHW3   A0A2C9JHV8   A0A2C9JHW6   A0A2T7NP87   A0A226F2U6   A0A0B7BAE7   A0A0B7B9S0   A0A0B7B9S6   A0A2S2Q285   K1PKI5   J9JPR2   Q7Z1D3   W4YV37   T1E1S3   A0A210R109   U4U150   C3Y1A6   R7TYU7   A0A2P6KVD9   A0A1D1VCM1   N6TQ25   A0A224YYY1   A0A3R7M2I2   A0A1L8DKY7   A0A1L8DL69   A0A0L8GYB8   A0A0L8GY73   A0A131YUV2   A0A131YWN0   B9UPG7   L7MI74   A0A2R5LIB2   A0A293MH51   A0A293LJS2   A0A0P4VHC4   A0A1V9XHT5   T1I867   A0A0V0G5T5   A0A069DZP2   A0A224X6E0   A0A0A9XYV5   A0A0K8SAY9   A0A0K8S9G3  

PDB

4EKU     E-value=4.80084e-23,     Score=262

KEGG

101745942    K05725 focal adhesion kinase 1 [EC:2.7.10.2] | (RefSeq) focal adhesion kinase 1

GO

GO:0005524   GO:0007172   GO:0005925   GO:0004713   GO:0005856   GO:0004672   GO:0043197   GO:0001525   GO:0042127   GO:0030155   GO:0007173   GO:0004715   GO:0030154   GO:0038083   GO:0016301   GO:0006418   GO:0004812   GO:0006468   GO:0004890   GO:0005216   GO:0043564   GO:0003824  

Length:

187

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00116

Exp number, first 60 AAs:

0.00032

Total prob of N-in:

0.02393

outside

1  -  187

 

 

Pi

246.448897

Theta

154.786229

Tajima's D

2.028537

CLR

0.180091

CSRT

0.887405629718514

Interpretation

Uncertain