Silkworm Genome Informatics Database

Gene

KWMTBOMO11890

Pre Gene Modal

BGIBMGA004453

Annotation

PREDICTED:_developmental_protein_eyes_absent_[Bombyx_mori]

Location

Bomo_Chr20(+):3132923-3164487 View in EpiBrowser

Full name

Eyes absent homolog

Location in the cell

Nuclear Reliability : 1.92

CDS

ATGAATGACGACAGCACCGGTGGCGTAAAAAGCGAGGTGCGGAGTCCGGGGCTTTGCGAGGCAGACGTGGCGCTGTACGGGGAAACGCTTCCATACGACCAGACCGCGCTGCCGTACCAATACTACAATAGTATGCAGCAGTATGGTAGCGGCAGCGCGGCTTCGTCGTACGTCAGCTCTGGTCTTTACAACCAGCCTTACGCTGCATATCCTCCACCGCACAACACGAACAACAGATCGTCATGCAAAGCGACGCCTACATACCTCAGTGCGTACGGGATGAGTGGAGTGGGAAGTGTGCCCGCCACAGGATTCGGCACTCAACCCTCGCCGTACGCATACTCTTCATACAACGGAGGACTATCGCAAACCTTCACTCCTACACAACAAGATTATAGTAATTATGCAGCCGGCTACGCGGAACACAATGTTGCTCAGTACAGTGGCTATTACGCAGCACCCAGCTATTCACCTTATGTCAGTTCGCCAAGCAGTAGTGGGAGCGCCGGTCACACTTCATACCATCTCGGAGGAGCATTGTCAGATTCACCATCATCAATGTTGCCATCAATTAATGATACGAGTCCATTATCTCCGATTAAAGCTGAAGTACACGCGGCCAGCAGAAGATGTAGAGAGAATTCTGGGGAAAGCACAGCTAGTAGGTCTCGAGGTCGAGGACGCAGGAACACCTCATCATCGCCAGCCCAGCACGTCCCAGAGCCAGCCACAGACAGAGTCTTCATATGGGATTTGGACGAGACTATAATTATATTCCATTCGTTGCTCACTGGAACTTATGCTACTAAGTACAATAAGGATACGCAACAGATAGTGCAATTAGGATTTAGGATGGAAGAAATGATATTCAGCTTGGCTGATACACATTTCTTTTTCAATGATGTTGAGGATTGCGACCAGGAGCACATAGACGCGGTATCGGCCGATGATAATGGCCAGGATCTCTCTGCGTACAACTTCACAACGGATGGGTTTCATGCGGGCGCGGCGGGAGGCGCTCTGTGTGCGCCTGGGGTGCGAGGCGGAGTCGACTGGATGAGGAAACTAGCCTTCCGGTACAGGAAGATCAAAGACACCTACAATAATTACAGGAATAGTGTTGGAGGGCTCCTAGGGCCAGCGAAGAGAGAACAGTGGTTACAGTTGAGAGCAGAACTTGAACAGGCCACGGATAACTGGTTAACATTAGCCTGCAAGTGTCTGAATATGATTAATTCTCGAGAGAACTGCGTGAATGTTTTAGTGACGACGACTCAGCTCGTCCCGGCTTTGGCTAAAGTCCTGCTCTTCGGTTTAGGGGGCGTGTTTCCTATCGAAAATATATACTCCGCCACGAAAACGGGTAAGGAGACTTGCTTTGAGAAAATTAAGCAGCGCTTCGGCGAGCGGTGCACGTACGTCGTCATAGGGGACGGCCAGGACGAGGAGGCCGCCGCCAAGGCCAAGAACTACCCTTTCTGGAGGGTGTCGAGCCACTCCGACATCGCGGCGCTGTACAACGCGCTCGACATGGGCTTCTTATGA

Protein

MNDDSTGGVKSEVRSPGLCEADVALYGETLPYDQTALPYQYYNSMQQYGSGSAASSYVSSGLYNQPYAAYPPPHNTNNRSSCKATPTYLSAYGMSGVGSVPATGFGTQPSPYAYSSYNGGLSQTFTPTQQDYSNYAAGYAEHNVAQYSGYYAAPSYSPYVSSPSSSGSAGHTSYHLGGALSDSPSSMLPSINDTSPLSPIKAEVHAASRRCRENSGESTASRSRGRGRRNTSSSPAQHVPEPATDRVFIWDLDETIIIFHSLLTGTYATKYNKDTQQIVQLGFRMEEMIFSLADTHFFFNDVEDCDQEHIDAVSADDNGQDLSAYNFTTDGFHAGAAGGALCAPGVRGGVDWMRKLAFRYRKIKDTYNNYRNSVGGLLGPAKREQWLQLRAELEQATDNWLTLACKCLNMINSRENCVNVLVTTTQLVPALAKVLLFGLGGVFPIENIYSATKTGKETCFEKIKQRFGERCTYVVIGDGQDEEAAAKAKNYPFWRVSSHSDIAALYNALDMGFL

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Cofactor

Mg(2+)

Similarity

Belongs to the HAD-like hydrolase superfamily. EYA family.

Uniprot

A0A2A4K9B5 A0A2W1BKA4 H9J4L3 A0A139WEH1 U4UF25 A0A1B6GUU1 + More
A0A1Y1K3J3 A0A0V0G919 A0A023F4A7 T1I6N0 A0A3Q0J329 A0A0A9XPY6 A0A0A9XMN0 A0A1S3K8L1 A0A1S3K814 A0A0D4RCA0 A0A1S3W7F5 A0A2Y9FR73 A0A340X1N4

EC Number

3.1.3.48

Pubmed

28756777 19121390 18362917 19820115 23537049 28004739 + More
25474469 25401762 26823975 25897375

EMBL

NWSH01000046 PCG80242.1 KZ150066 PZC74135.1 BABH01021921 KQ971354 + More
KYB26324.1 KB632263 ERL90918.1 GECZ01003578 JAS66191.1 GEZM01093997 JAV56019.1 GECL01001733 JAP04391.1 GBBI01002735 JAC15977.1 ACPB03005128 GBHO01041401 GBHO01022696 JAG02203.1 JAG20908.1 GBHO01022698 GBHO01022695 GBRD01007973 GBRD01007972 GDHC01011693 JAG20906.1 JAG20909.1 JAG57848.1 JAQ06936.1 KP168452 AJV21307.1

Proteomes

UP000218220 UP000005204 UP000007266 UP000030742 UP000015103 UP000079169 + More
UP000085678 UP000079721 UP000265300

PRIDE

H9J4L3

Interpro

IPR006545   EYA_dom        + More
IPR028472   EYA_fam
IPR038102   EYA_dom_sf
IPR036412   HAD-like_sf
IPR028471   Eyes_absent_h1
IPR028478   EYA4

SUPFAM

SSF56784 SSF56784

Gene 3D

3.40.50.12350

CDD

cd02601 HAD_Eya

ProteinModelPortal

A0A2A4K9B5 A0A2W1BKA4 H9J4L3 A0A139WEH1 U4UF25 A0A1B6GUU1 + More
A0A1Y1K3J3 A0A0V0G919 A0A023F4A7 T1I6N0 A0A3Q0J329 A0A0A9XPY6 A0A0A9XMN0 A0A1S3K8L1 A0A1S3K814 A0A0D4RCA0 A0A1S3W7F5 A0A2Y9FR73 A0A340X1N4

PDB

3HB1 E-value=3.18149e-111, Score=1028

KEGG

101743062 K17622 eyes absent homolog 4 [EC:3.1.3.48] | (RefSeq) developmental protein eyes absent

GO

GO:0007275 GO:0004725 GO:0046872 GO:0016576 GO:2001240 GO:0045739 GO:0005634 GO:0048856 GO:0007605 GO:0016020 GO:0016780 GO:0006470 GO:0008138 GO:0004890 GO:0005216 GO:0043564 GO:0006418 GO:0003824

PANTHER

PTHR10190 PTHR10190:SF11 PTHR10190:SF17

Length:

514

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.29131

Exp number, first 60 AAs:

0.00315

Total prob of N-in:

0.02001

outside

1 - 514

Pi

200.780659

Theta

147.100266

Tajima's D

0.605487

CLR

0.297661

CSRT

0.548172591370432

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics