Gene

KWMTBOMO11858

Annotation

PREDICTED:_uncharacterized_protein_LOC105395428_[Plutella_xylostella]

Location

Bomo_Chr20(+):2198073-2201977      View in EpiBrowser

Full name

Biogenesis of lysosome-related organelles complex 1 subunit 6      

Alternative Name

Pallid protein homolog

Location in the cell

Nuclear   Reliability : 1.942

CDS

ATGGAAAATACCGAGAAAGCAGATTTGAATGACGCGAAGACTTGTAACTTACTGGCCAAAGGTATTTTGGAGTTGTACGAACCACCATTGACAACAATAAACACTCATTTGAAGGAATTAACGGAAAAGCAAGATGCTATACACAACACAATAAAATTTGAGAGGCAAAAGCTAGAAGATATACAGAATGATGCAATGCTGGATGCAATGTTAGCCGATATTGCAACAAACAGAGAAAAACTATTAACCATATCGAATTCAATGATGGTACTACATAAAAGAGTGCAATCGTTACAGGTCAGGGCAGCCAATGTAGAAAAGGCAGCTAACACTAGAGCTGCTATCAGTAAACATACAAGGAGTTGA

Protein

MENTEKADLNDAKTCNLLAKGILELYEPPLTTINTHLKELTEKQDAIHNTIKFERQKLEDIQNDAMLDAMLADIATNREKLLTISNSMMVLHKRVQSLQVRAANVEKAANTRAAISKHTRS

Description

Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis.
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis and membrane trafficking in synapses (PubMed:20015953, PubMed:28317021). In response to high synaptic activity at neuromuscular junctions, plays a key role in promoting efficient synaptic vesicle recycling and re-formation through early endosomes (PubMed:28317021).

Subunit

Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) composed of Blos1, Blos2, Blos3, Blos4, Dysb, Muted, Pldn and Snapin. Interacts with Blos1, Blos4 and Dysb.

Similarity

Belongs to the BLOC1S6 family.

Keywords

Cell junction   Coiled coil   Complete proteome   Cytoplasm   Cytoskeleton   Reference proteome   Synapse  

Feature

chain  Biogenesis of lysosome-related organelles complex 1 subunit 6

Uniprot

H9J4J7   A0A3S2LHS8   A0A2W1BXU0   A0A2A4J0G1   A0A2H1WII4   A0A212FAF5   + More
A0A0N1INY3   A0A194QBC9   A0A0A1X151   B4LCQ7   A0A1B0CQH7   A0A3B0J569   B4N4M1   A0A067RGA5   B3M4A8   B4HAH5   Q2LZ74   A0A1Y1MB77   W8AUL4   A0A0K8UNC7   A0A1I8MMP5   A0A034VEJ9   A0A1W4VUX5   A0A0C9RYD6   Q16MT0   A0A0R3P528   U5EU79   B0XL90   B4QQ96   B4HEX1   A0A1S4FTR9   Q4QPX0   A0A0J9RTE4   B3NGZ0   Q9VTM0   B4J2I8   B4PFM6   A0A1Q3F852   A0A026WSX1   A0A0L0CGH5   C6SUX8   A0A1I8P6T6   A0A1W7R7X7   Q16Q01   A0A1X7U972   E2C3D6   A0A1W4XK20   A0A099Z3I6   A0A182GXH4   V5H063   T2M3U0   D6WQP3   A0A1L8DTG2   A0A0A0AIB6   T1DHS6  

Pubmed

19121390    28756777    22118469    26354079    25830018    17994087    + More
24845553    15632085    28004739    24495485    25315136    25348373    17510324    22936249    10731132    12537572    20015953    28317021    17550304    24508170    30249741    26108605    20798317    26483478    24065732    18362917    19820115   

EMBL

BABH01021842    RSAL01000114    RVE46932.1    KZ149924    PZC77630.1    NWSH01004126    + More
PCG65471.1    ODYU01008553    SOQ52254.1    AGBW02009482    OWR50712.1    KQ460900    KPJ10826.1    KQ459460    KPJ00736.1    GBXI01010177    GBXI01009944    JAD04115.1    JAD04348.1    CH940647    EDW70949.1    AJWK01023566    OUUW01000002    SPP76775.1    CH964095    EDW79095.2    KK852657    KDR19214.1    CH902618    EDV39378.1    CH479240    EDW37573.1    CH379069    EAL29634.2    GEZM01035974    GEZM01035973    GEZM01035972    GEZM01035971    JAV83069.1    GAMC01014040    JAB92515.1    GDHF01024306    JAI28008.1    GAKP01018955    GAKP01018954    JAC39998.1    GBYB01012981    JAG82748.1    CH477850    EAT35650.1    KRT08222.1    GANO01004005    JAB55866.1    DS234361    EDS33724.1    CM000363    EDX10114.1    CH480815    EDW41140.1    BT023646    AAY85046.1    CM002912    KMY99041.1    CH954178    EDV51447.2    AE014296    CH916366    EDV97073.1    CM000159    EDW94175.1    GFDL01011294    JAV23751.1    KK107119    QOIP01000009    EZA58776.1    RLU18334.1    JRES01000502    KNC30599.1    BT088970    ACT82952.1    GEHC01000420    JAV47225.1    CH477767    EAT36449.1    GL452320    EFN77474.1    KL889629    KGL76979.1    JXUM01095290    KQ564186    KXJ72608.1    GALX01000864    JAB67602.1    HAAD01000395    CDG66627.1    KQ971354    EFA06046.2    GFDF01004336    JAV09748.1    KL871964    KGL94224.1    GAMD01002186    JAA99404.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053240    UP000053268    + More
UP000008792    UP000092461    UP000268350    UP000007798    UP000027135    UP000007801    UP000008744    UP000001819    UP000095301    UP000192221    UP000008820    UP000002320    UP000000304    UP000001292    UP000008711    UP000000803    UP000001070    UP000002282    UP000053097    UP000279307    UP000037069    UP000095300    UP000007879    UP000008237    UP000192223    UP000053641    UP000069940    UP000249989    UP000007266    UP000053858   

PRIDE

H9J4J7    Q4QPX0    Q9VTM0   

Pfam

PF14712   Snapin_Pallidin        + More
PF01470   Peptidase_C15

Interpro

IPR028119   Snapin/Pallidin/Snn1        + More
IPR017242   BLOC-1_pallidin       
IPR036440   Peptidase_C15-like_sf       
IPR016125   Peptidase_C15-like       
IPR000816   Peptidase_C15       

SUPFAM

SSF53182   SSF53182       

Gene 3D

3.40.630.20    

CDD

cd00501  Peptidase_C15

ProteinModelPortal

H9J4J7   A0A3S2LHS8   A0A2W1BXU0   A0A2A4J0G1   A0A2H1WII4   A0A212FAF5   + More
A0A0N1INY3   A0A194QBC9   A0A0A1X151   B4LCQ7   A0A1B0CQH7   A0A3B0J569   B4N4M1   A0A067RGA5   B3M4A8   B4HAH5   Q2LZ74   A0A1Y1MB77   W8AUL4   A0A0K8UNC7   A0A1I8MMP5   A0A034VEJ9   A0A1W4VUX5   A0A0C9RYD6   Q16MT0   A0A0R3P528   U5EU79   B0XL90   B4QQ96   B4HEX1   A0A1S4FTR9   Q4QPX0   A0A0J9RTE4   B3NGZ0   Q9VTM0   B4J2I8   B4PFM6   A0A1Q3F852   A0A026WSX1   A0A0L0CGH5   C6SUX8   A0A1I8P6T6   A0A1W7R7X7   Q16Q01   A0A1X7U972   E2C3D6   A0A1W4XK20   A0A099Z3I6   A0A182GXH4   V5H063   T2M3U0   D6WQP3   A0A1L8DTG2   A0A0A0AIB6   T1DHS6  

KEGG

101743487    K20188 biogenesis of lysosome-related organelles complex 1 subunit 6 | (RefSeq) uncharacterized LOC1

GO

GO:0031083   GO:0061174   GO:0036466   GO:0008057   GO:0098975   GO:0016021   GO:0005856   GO:0030018   GO:0030054   GO:0006508   GO:0005829   GO:0016920  

PANTHER

PTHR23402  

Subcellular location

Cell junction   At the neuromuscular junctions, present at both pre-and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.   With evidence from 3 publications.
Synapse   At the neuromuscular junctions, present at both pre-and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.   With evidence from 3 publications.
Cytoplasm   At the neuromuscular junctions, present at both pre-and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.   With evidence from 3 publications.
Cytoskeleton   At the neuromuscular junctions, present at both pre-and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.   With evidence from 3 publications.
Myofibril   At the neuromuscular junctions, present at both pre-and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.   With evidence from 3 publications.
Sarcomere   At the neuromuscular junctions, present at both pre-and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.   With evidence from 3 publications.
Z line   At the neuromuscular junctions, present at both pre-and postsynaptic compartments where it associates with cytoskeletal neuronal microtubule structures and muscle Z-lines.   With evidence from 3 publications.

Length:

121

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.000590000000000001

Exp number, first 60 AAs:

0.0004

Total prob of N-in:

0.39595

outside

1  -  121

 

 

Pi

200.947847

Theta

159.462417

Tajima's D

0.613529

CLR

0.087424

CSRT

0.549072546372681

Interpretation

Uncertain