Gene

KWMTBOMO11856

Pre Gene Modal

BGIBMGA004436

Annotation

PREDICTED:_facilitated_trehalose_transporter_Tret1-like_[Amyelois_transitella]

Location

Bomo_Chr20(+):2154853-2158317      View in EpiBrowser

Full name

Facilitated trehalose transporter Tret1      

Location in the cell

PlasmaMembrane   Reliability : 4.982

CDS

ATGACAGCTATAGAAAATAAATACATAATTTCCGATAAGACAGCCGTCAAAGCATTCTGGGTGGCACTAATCGTGAATTTGACTCGTGAATTCTGCGGTTGCATCGCGATCCTGGTGTACGCGAGTCACATCTTCACGGCAGCCCGTAAAGACCCGAACATCAGTATATCTTTGTCTCCGAACAAGCAGTCTATCATGTTGGCAGCTGTTCAGATCGTAGGCTCATTCCTGGCCTGTCAACTAGTCGATAGAGCCGGCAGGAAGCCTCTTCTAGCGGTCACAAGCGTGGTGGCTGGATTCAGCATGGCTCTGCTCGGAGTCTGGTTCTACCTCCAGGGCATTGGCGTGTTCATGCCTGGATGGGTGCCGATAGCAGCGCTCTGCATCTGCATATTCGCAGACGCATCGGGACTCCAACCGCTACCGTTCGTCATAATGACAGAGATGTTTAGTTTCCAGCTCCGTGGTACAGTGGCGACTTTAGTTATGGCAATATCTCTGGCAACAGACTTCGCTCTGCTGAGACTGTTCGCTCCATTGACCGAGCTGATTGGCTATCACTTCACATTCTGGATGTTCAGTTTAATATGTCTCTCGAACGTATTCTATCTAATCTTCTGTGTTCCGGAAACAAAAATGAGGAGCTTAGAGGACATTTACGCCGATTTAGAAGGAAAGAATAAGAGAAAAAAGAAATCGGACGAAGTGGTTGAAACAAACCACGTCTAA

Protein

MTAIENKYIISDKTAVKAFWVALIVNLTREFCGCIAILVYASHIFTAARKDPNISISLSPNKQSIMLAAVQIVGSFLACQLVDRAGRKPLLAVTSVVAGFSMALLGVWFYLQGIGVFMPGWVPIAALCICIFADASGLQPLPFVIMTEMFSFQLRGTVATLVMAISLATDFALLRLFAPLTELIGYHFTFWMFSLICLSNVFYLIFCVPETKMRSLEDIYADLEGKNKRKKKSDEVVETNHV

Description

High-capacity facilitative transporter for trehalose. Does not transport maltose, sucrose or lactose. Mediates the bidirectional transfer of trehalose. Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph.

Biophysicochemical Properties

71.58 mM for trehalose

Similarity

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.

Keywords

Cell membrane   Complete proteome   Glycoprotein   Membrane   Reference proteome   Sugar transport   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Facilitated trehalose transporter Tret1

Uniprot

H9J4J6   A0A2W1BRA6   A0A3S2TIH7   A0A2A4J8P9   A0A2H1WGI4   A0A194Q5B9   + More
A0A212FAG2   A0A0L7L0N1   H9J474   H9J4P6   A0A2H1WB87   A0A0N0PER8   A0A3S2TMD3   A0A194Q5F6   A0A2A4JHM3   A0A194Q5M1   A0A194QQ84   A0A2H1WE18   A0A212EX46   A0A2A4JII3   A0A3S2L5Q4   A0A2W1BV28   A0A212FI50   A0A0N1IIG7   A0A0L7LE34   A0A2W1BSA0   A0A194Q5G2   A0A212FB89   A0A212F931   A0A194QB83   A0A2Z5U782   A0A212F0G4   A0A2H1WR29   H9JVU3   A0A194Q5F7   A0A2A4J7G4   A0A2H1WQ53   A0A2W1BQ47   A0A0L7KVL6   A0A0N0PEG1   S4PKR1   A0A0N1IHX2   A0A2P8Z801   A0A2J7R8L3   A0A2P8ZDM8   A0A067R867   A0A2P8XJ31   A0A0A8J8K5   A0A0K8UFA2   A0A2J7QIE7   H9JFD4   A0A034VPA7   A0A0K8UNM6   A0A2P8YD54   A0A2J7QIG3   A0A194PUK5   A0A194QBF3   A0A194RFW2   A0A2J7QIF3   A0A2J7QIF2   A0A182GLX7   K7IWX4   A0A0A9W6S1   A0A2J7PYX6   A0A1B0CYE5   A0A0A1WTN4   A0A1Z1XG23   A0A0A1WG49   A0A1L8DIK0   A0A195FTD3   Q173Q9   A0A1L8DIL6   A0A146LSN9   A0A2H1WIP5   A0A182I799   A0A182F539   A0A2M4BLL7   A0A182JZA6   A0A023EU84   A0A2M4BLK9   A0A2M3Z412   A0A182FCI5   A0A2M3ZH26   A9ZSY3   Q16Q84   A0A2M4A739   A0A2M4A741   A0A2M4A7E4   T1DKQ7   A0A194PK39   A0A2M3YZE1   A0A2M3Z428   A0A182LMV4   A0A182K5N6   A0A182UZ66  

Pubmed

19121390    28756777    26354079    22118469    26227816    23622113    + More
29403074    24845553    25348373    26483478    20075255    25401762    25830018    28588501    17510324    26823975    24945155    20035867    20966253   

EMBL

BABH01021836    KZ149924    PZC77632.1    RSAL01000114    RVE46930.1    NWSH01002620    + More
PCG67830.1    ODYU01008186    SOQ51574.1    KQ459460    KPJ00738.1    AGBW02009482    OWR50710.1    JTDY01003914    KOB68834.1    BABH01032501    BABH01022059    ODYU01007510    SOQ50341.1    KQ459838    KPJ19739.1    RSAL01000053    RVE50024.1    KPJ00782.1    NWSH01001423    PCG71276.1    KPJ00847.1    KQ461181    KPJ07673.1    ODYU01008039    SOQ51308.1    AGBW02011864    OWR46004.1    NWSH01001270    PCG71905.1    RSAL01000132    RVE46342.1    KZ149954    PZC76506.1    AGBW02008435    OWR53407.1    KPJ19742.1    JTDY01001495    KOB73737.1    PZC76505.1    KPJ00783.1    AGBW02009367    OWR50987.1    AGBW02009650    OWR50256.1    KPJ00686.1    AP017499    BBB06788.1    AGBW02011078    OWR47246.1    ODYU01010429    SOQ55525.1    BABH01040655    KPJ00778.1    NWSH01002833    PCG67464.1    ODYU01010219    SOQ55189.1    KZ149937    PZC77108.1    JTDY01005298    KOB67145.1    KPJ19738.1    GAIX01000896    JAA91664.1    KQ460009    KPJ18480.1    PYGN01000154    PSN52620.1    NEVH01006721    PNF37174.1    PYGN01000088    PSN54598.1    KK852870    KDR14605.1    PYGN01001954    PSN32011.1    AB901068    BAQ02368.1    GDHF01026962    JAI25352.1    NEVH01013595    PNF28370.1    BABH01038299    GAKP01015559    GAKP01015558    GAKP01015557    JAC43393.1    GDHF01024196    GDHF01015258    GDHF01004851    JAI28118.1    JAI37056.1    JAI47463.1    PYGN01000690    PSN42188.1    PNF28369.1    KQ459597    KPI94820.1    KPJ00761.1    KQ460207    KPJ16703.1    PNF28367.1    PNF28368.1    JXUM01001466    KQ560121    KXJ84364.1    AAZX01006527    AAZX01008308    GBHO01043034    GBRD01007348    GBRD01004279    JAG00570.1    JAG58473.1    NEVH01020342    PNF21526.1    AJVK01000088    GBXI01012080    JAD02212.1    KY350170    ARX98209.1    GBXI01016924    JAC97367.1    GFDF01007796    JAV06288.1    KQ981276    KYN43567.1    CH477418    EAT41278.1    GFDF01007788    JAV06296.1    GDHC01008360    GDHC01004923    JAQ10269.1    JAQ13706.1    ODYU01008931    SOQ52939.1    APCN01003374    GGFJ01004829    MBW53970.1    GAPW01001101    JAC12497.1    GGFJ01004828    MBW53969.1    GGFM01002508    MBW23259.1    GGFM01007009    MBW27760.1    AB369550    BAF96744.1    CH477758    EAT36546.1    GGFK01003278    MBW36599.1    GGFK01003296    MBW36617.1    GGFK01003378    MBW36699.1    GAMD01000836    JAB00755.1    KQ459601    KPI93687.1    GGFM01000865    MBW21616.1    GGFM01002530    MBW23281.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053268    UP000007151    UP000037510    + More
UP000053240    UP000245037    UP000235965    UP000027135    UP000069940    UP000249989    UP000002358    UP000092462    UP000078541    UP000008820    UP000075840    UP000069272    UP000075881    UP000075882    UP000075903   

PRIDE

H9J4J6    H9J474    H9J4P6    H9JVU3    H9JFD4    A9ZSY3    + More

Pfam

PF00083   Sugar_tr        + More
PF00025   Arf
PF05225   HTH_psq

Interpro

IPR005828   MFS_sugar_transport-like        + More
IPR020846   MFS_dom       
IPR005829   Sugar_transporter_CS       
IPR036259   MFS_trans_sf       
IPR003663   Sugar/inositol_transpt       
IPR006689   Small_GTPase_ARF/SAR       
IPR027417   P-loop_NTPase       
IPR009057   Homeobox-like_sf       
IPR007889   HTH_Psq       

SUPFAM

SSF103473   SSF103473        + More
SSF52540   SSF52540       
SSF46689   SSF46689       

CDD

cd06174  MFS

ProteinModelPortal

H9J4J6   A0A2W1BRA6   A0A3S2TIH7   A0A2A4J8P9   A0A2H1WGI4   A0A194Q5B9   + More
A0A212FAG2   A0A0L7L0N1   H9J474   H9J4P6   A0A2H1WB87   A0A0N0PER8   A0A3S2TMD3   A0A194Q5F6   A0A2A4JHM3   A0A194Q5M1   A0A194QQ84   A0A2H1WE18   A0A212EX46   A0A2A4JII3   A0A3S2L5Q4   A0A2W1BV28   A0A212FI50   A0A0N1IIG7   A0A0L7LE34   A0A2W1BSA0   A0A194Q5G2   A0A212FB89   A0A212F931   A0A194QB83   A0A2Z5U782   A0A212F0G4   A0A2H1WR29   H9JVU3   A0A194Q5F7   A0A2A4J7G4   A0A2H1WQ53   A0A2W1BQ47   A0A0L7KVL6   A0A0N0PEG1   S4PKR1   A0A0N1IHX2   A0A2P8Z801   A0A2J7R8L3   A0A2P8ZDM8   A0A067R867   A0A2P8XJ31   A0A0A8J8K5   A0A0K8UFA2   A0A2J7QIE7   H9JFD4   A0A034VPA7   A0A0K8UNM6   A0A2P8YD54   A0A2J7QIG3   A0A194PUK5   A0A194QBF3   A0A194RFW2   A0A2J7QIF3   A0A2J7QIF2   A0A182GLX7   K7IWX4   A0A0A9W6S1   A0A2J7PYX6   A0A1B0CYE5   A0A0A1WTN4   A0A1Z1XG23   A0A0A1WG49   A0A1L8DIK0   A0A195FTD3   Q173Q9   A0A1L8DIL6   A0A146LSN9   A0A2H1WIP5   A0A182I799   A0A182F539   A0A2M4BLL7   A0A182JZA6   A0A023EU84   A0A2M4BLK9   A0A2M3Z412   A0A182FCI5   A0A2M3ZH26   A9ZSY3   Q16Q84   A0A2M4A739   A0A2M4A741   A0A2M4A7E4   T1DKQ7   A0A194PK39   A0A2M3YZE1   A0A2M3Z428   A0A182LMV4   A0A182K5N6   A0A182UZ66  

PDB

4GC0     E-value=1.21334e-12,     Score=174

KEGG

101743250    K08145 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member

GO

GO:0016021   GO:0022857   GO:0008643   GO:0005525   GO:0003677   GO:0005886   GO:0015574   GO:0015771   GO:0005215   GO:0007631   GO:0016499   GO:0004890   GO:0005216   GO:0043564   GO:0006418   GO:0003824   GO:0055085  

Subcellular location

Cell membrane  

Length:

242

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

129.32201

Exp number, first 60 AAs:

22.71157

Total prob of N-in:

0.94862

POSSIBLE N-term signal

sequence

inside

1  -  18

TMhelix

19  -  41

outside

42  -  64

TMhelix

65  -  82

inside

83  -  88

TMhelix

89  -  111

outside

112  -  120

TMhelix

121  -  143

inside

144  -  155

TMhelix

156  -  178

outside

179  -  182

TMhelix

183  -  205

inside

206  -  242

 

 

Pi

196.179552

Theta

159.323272

Tajima's D

0.720404

CLR

0

CSRT

0.577771111444428

Interpretation

Possibly Positive selection