Gene

KWMTBOMO11844

Pre Gene Modal

BGIBMGA004429

Annotation

neuropeptide_receptor_A5_precursor_[Bombyx_mori]

Location

Bomo_Chr20(-):1761641-1807153      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.959

CDS

ATGGCACTTAGAAAAGAATCCTTGGCCATAATCACGATGTTGATCATATGCAATTACGTCCTAAGTTCAAACTTCGATTCGATACCAGAGAGCATCAGAGTAAGAAAGTCCGTTGATAACACCACTTCGAGGAGTAGCCTAAAAAATTTAAACGAGACAATGAAACAAAGCAATAATGAAACTGAATTTGGAAGGCTTCTAGATGCAACCGAAATGACAACTGAATATGATAATTTCACTGAAGAGCCCTGCGTTGGCGACCGGGCCTTCTGCAATTTGACCAGAGAGGAGTACATGGAGATGCTGAATGATTACGTGTTCCCTCAGCCCTACGAATGGGTACTCATAGCTACTCACGCCATAGTATTTGTGATCGGGCTGATAGGGAATGCGCTTGTCTGCATAGCGGTGTATAGAAATCATTCCATGAGAACTGTCACGAATTATTTCATCGTGAATCTGGCTGTGGCCGATTTTATGGTGATATTGATATGTCTGCCGCCGACTGTGCTCTGGGACGTCACCGAAACCTGGTTCTTTGGGACAGCCATGTGCAGGATCGTCCTGTACTTTCAGTCAGTGTCAGTGACGGTGTCAGTTCTGACGCTGACGTTCATCTCTGTGGACCGCTGGTACGCTATCTGCTTCCCGCTGAAGTTCAAGTCAACCACGGGCCGCGCCAAGACCGCTATACTGATTATATGGCTTCTATCTCTACTATTCAATATACCGGAATTCGTGGTGCTTCAAGTGCAAACGAAGATGCAGCTGCGCTTCAACGTGCAATACTTCATGCAGTGCGCTTCCACTTGGTCTGATGAAAGCGATCTGACTTGGCACATCATAAAGGCACTGTTTCTGTATACATTCCCGCTATTGCTGATGACGATCGCGTACTGTCAAATCGTACGAGTCCTTTGGAGATCAGACAACATTCCTGGCCACACTGAATCCCACAAGCTGTGCAGCACGCAAACAGGGCAGAGCAATTGGCTGGCGGCATCTCGACGCACAACGCCATCGATCCACACGAACGCCTCCACCGAGGGTCAGCTTCGGTCACGGCGGAAGGCCGCCAAGATGCTGGTGGCTGTGGTAGCGATGTTCGCTGTTTGTTACTTCCCGGTACACCTCCTCTCTGTATTAAGGGTCGCTTTTGACGTGCAACAAACAGACGTGATGACCTGCATCGCTCTGATATCACACGTGATGTGTTACGCGAACTCCGCCGTCAACCCGCTGATTTACAACTTCATGAGCGGGAAATTCCGTCGCGAATTCCACAGATCGTACTTCAAATGTTTCTGCTGCTGTCACACCACGCCGGCGCCAGAACAGAATGGGGCTTCGTTTGAGCCAATCGGCAGTTCTAGAGCTCGGACCATCCGCACCACGGTCCGACGGCACGACTCCTGCGTCAGCTATCGACTCGCCCATCTGTCACCGTCGAACCACAACATTCACCGGGACTACATTCAAAATACGAACACGTCTTTTATCGAGCCAATGAACGGAAATCGCAGGTCTAAAATCAGGGACGAATCGATCAGCGACACCGCGACACGTTTCACGGTGACCACCGATATCCCTTGTAAAGATTGA

Protein

MALRKESLAIITMLIICNYVLSSNFDSIPESIRVRKSVDNTTSRSSLKNLNETMKQSNNETEFGRLLDATEMTTEYDNFTEEPCVGDRAFCNLTREEYMEMLNDYVFPQPYEWVLIATHAIVFVIGLIGNALVCIAVYRNHSMRTVTNYFIVNLAVADFMVILICLPPTVLWDVTETWFFGTAMCRIVLYFQSVSVTVSVLTLTFISVDRWYAICFPLKFKSTTGRAKTAILIIWLLSLLFNIPEFVVLQVQTKMQLRFNVQYFMQCASTWSDESDLTWHIIKALFLYTFPLLLMTIAYCQIVRVLWRSDNIPGHTESHKLCSTQTGQSNWLAASRRTTPSIHTNASTEGQLRSRRKAAKMLVAVVAMFAVCYFPVHLLSVLRVAFDVQQTDVMTCIALISHVMCYANSAVNPLIYNFMSGKFRREFHRSYFKCFCCCHTTPAPEQNGASFEPIGSSRARTIRTTVRRHDSCVSYRLAHLSPSNHNIHRDYIQNTNTSFIEPMNGNRRSKIRDESISDTATRFTVTTDIPCKD

Similarity

Belongs to the G-protein coupled receptor 1 family.

Uniprot

B3XXL7   A0A0S1YD65   A0A0N0PF28   A0A0N1IB59   A0A2A4J7H0   A0A0E3EKU4   + More
A0A345ANM7   F1CZQ1   A0A0S1YD80   B3XXM9   A0A212FAI2   G3JWZ1   U5N0U6   A0A1B6KTL7   U3U4E1   A0A1B6JDZ3   A0A2C9GPU2   A0A1B6C133   A0A1S4GM37   I6NNS5   A0A310SW43   K7IWF9   A0A154PAQ2   A0A0A9WMC0   A0A087ZYQ8   A0A0A9WR33   A0A2U9PG22   A0A0P5AJC7   A0A0P5NAX8   A0A195FJP6   A0A0N8DCT1   A0A0N8BU42   A0A0P5KQM3   A0A162P288   A0A0P6F5P7   A0A0P5T2I6   A0A0C9R4T1   A0A026W5R0   A0A151ITZ3   A0A1W4XMD0   A0A195BFF0   A0A1S3D076   A0A2I7NB16   A0A0K0PUH3   A0A0K0PVS5   A0A1W0WY80   R7VBE1   A0A2C9JHH0  

Pubmed

18725956    26354079    21699978    22118469    21839791    24130914    + More
23932938    12364791    25814925    20075255    25401762    26823975    24508170    29326594    26190115    23254933    15562597   

EMBL

AB330425    BAG68403.1    KT031002    ALM88300.1    LADI01012895    KPJ20751.1    + More
KQ459718    KPJ20254.1    NWSH01002529    PCG68067.1    KF881015    AIT70966.1    MF770987    AXF38049.1    HQ634154    ADX66344.1    KT031014    ALM88312.1    AB330437    BAG68415.1    AGBW02009467    OWR50755.1    JN030894    AEN03789.1    KC439534    AGX85002.1    GEBQ01025181    JAT14796.1    AB817299    BAO01066.1    GECU01010359    JAS97347.1    APCN01005316    GEDC01030319    JAS06979.1    AAAB01008968    JN543509    AEX08666.2    KQ759870    OAD62416.1    KQ434864    KZC09016.1    GBHO01034664    GBHO01034660    GDHC01012203    GDHC01004088    JAG08940.1    JAG08944.1    JAQ06426.1    JAQ14541.1    GBHO01034662    GBHO01034661    GDHC01019905    JAG08942.1    JAG08943.1    JAP98723.1    MG550205    AWT50639.1    GDIP01198480    JAJ24922.1    GDIQ01144722    JAL07004.1    KQ981522    KYN40586.1    GDIP01046399    JAM57316.1    GDIQ01144723    JAL07003.1    GDIQ01182063    JAK69662.1    LRGB01000512    KZS18457.1    GDIQ01065110    JAN29627.1    GDIQ01097150    JAL54576.1    GBYB01002980    GBYB01002983    JAG72747.1    JAG72750.1    KK107390    EZA51412.1    KQ980970    KYN10929.1    KQ976504    KYM82895.1    MF467262    AUR53643.1    KP293976    AKQ63030.1    KP294022    AKQ63076.1    MTYJ01000032    OQV20160.1    AMQN01004356    KB293301    ELU16138.1   

Proteomes

UP000053268    UP000053240    UP000218220    UP000007151    UP000075840    UP000002358    + More
UP000076502    UP000005203    UP000078541    UP000076858    UP000053097    UP000078492    UP000192223    UP000078540    UP000079169    UP000014760    UP000076420   

PRIDE

B3XXL7    B3XXM9   

Pfam

PF00001   7tm_1

Interpro

IPR017452   GPCR_Rhodpsn_7TM        + More
IPR000276   GPCR_Rhodpsn       
IPR000204   Orexin_rcpt       
IPR000611   NPY_rcpt       

CDD

cd15208  7tmA_OXR

ProteinModelPortal

B3XXL7   A0A0S1YD65   A0A0N0PF28   A0A0N1IB59   A0A2A4J7H0   A0A0E3EKU4   + More
A0A345ANM7   F1CZQ1   A0A0S1YD80   B3XXM9   A0A212FAI2   G3JWZ1   U5N0U6   A0A1B6KTL7   U3U4E1   A0A1B6JDZ3   A0A2C9GPU2   A0A1B6C133   A0A1S4GM37   I6NNS5   A0A310SW43   K7IWF9   A0A154PAQ2   A0A0A9WMC0   A0A087ZYQ8   A0A0A9WR33   A0A2U9PG22   A0A0P5AJC7   A0A0P5NAX8   A0A195FJP6   A0A0N8DCT1   A0A0N8BU42   A0A0P5KQM3   A0A162P288   A0A0P6F5P7   A0A0P5T2I6   A0A0C9R4T1   A0A026W5R0   A0A151ITZ3   A0A1W4XMD0   A0A195BFF0   A0A1S3D076   A0A2I7NB16   A0A0K0PUH3   A0A0K0PVS5   A0A1W0WY80   R7VBE1   A0A2C9JHH0  

PDB

5WS3     E-value=3.24933e-54,     Score=537

KEGG

100187564    K04239 hypocretin (orexin) receptor 2 | (RefSeq) NGR-A5, BNGR-A5; neuropeptide receptor A5

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0016499   GO:0016021   GO:0007631   GO:0007218   GO:0004983   GO:0007186   GO:0004930   GO:0004890   GO:0005216   GO:0043564   GO:0006418   GO:0003824  

SignalP

Position:   1 - 22,         Likelihood:  0.715154

 

 

Length:

533

Number of predicted TMHs:

8

Exp number of AAs in TMHs:

174.50603

Exp number, first 60 AAs:

17.72977

Total prob of N-in:

0.86571

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  114

TMhelix

115  -  137

inside

138  -  148

TMhelix

149  -  171

outside

172  -  185

TMhelix

186  -  208

inside

209  -  228

TMhelix

229  -  251

outside

252  -  284

TMhelix

285  -  307

inside

308  -  361

TMhelix

362  -  384

outside

385  -  393

TMhelix

394  -  416

inside

417  -  533

 

 

Pi

196.491803

Theta

155.222588

Tajima's D

0.513778

CLR

0.301761

CSRT

0.51902404879756

Interpretation

Uncertain