Gene

KWMTBOMO11824

Pre Gene Modal

BGIBMGA013690

Annotation

PREDICTED:_ionotropic_GABA-aminobutyric_acid_receptor_RDL3_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr20(+):1150517-1164289      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.336

CDS

ATGAGCGCCGTGCGTCACGCCGCGCTTCTCCTCGCGCTTGCCGCCACCTTCTTGCCGCAGGCCAATCGTGTCGCCGGCGGCGGTGGAGGTGGAATGTTCGGTGATGTCAATATATCAGCTATCTTGGATTCGTTCAGCATCAGCTATGATAAGCGAGTAAGACCAAACTATGGAGGTCCCCCCGTGGAAGTCGGCGTCACCATGTACGTCCTGTCCATCAGCTCCGTGTCTGAAGTCCTCATGGACTTCACTCTGGACTTCTACTTCAGACAGTTCTGGACAGATCCGCGACTGGCCTACAAGAAGCGACCAGGCGTGGAAACCCTGTCCGTGGGCTCGGAGTTCATCAAGAACATCTGGGTACCGGACACGTTCTTTGTCAACGAAAAGCAATCGTATTTCCACATAGCCACAACGAGCAACGAATTTATTAGGATTCACCACTCCGGCTCGATAACAAGGAGTATTAGATTAACGATCACTGCGTCATGTCCCATGAACCTGCAGTATTTCCCCATGGACCGGCAGCTTTGCCACATCGAGATTGAAAGCTTCGGCTACACGATGCGCGACATCCGCTACAAGTGGAACGAGGGACCCAACTCGGTGGGCGTCTCCAAGGAAGTGTCGCTGCCGCAGTTCAAGGTGCTCGGACACCGCCAGCGCGCCATGGAGATCTCGCTCACAACAGGGAATTACTCAAGGCTGGCGTGCGAAATACAGTTCGTACGCTCGATGGGGTACTACCTCATCCAGATCTACATACCTTCGGGTCTGATCGTGATCATATCGTGGGTCTCGTTCTGGCTGAACCGGAACGCGACCCCGGCCCGCGTGCAGCTAGGGGTCACCACCGTGCTGACGATGACAACGCTCATGTCATCGACCAACGCCGCTCTGCCGAAGATATCATACGTCAAGTCTATCGACGTGTACCTCGGGACCTGCTTCGTCATGGTTTTCACGAGCTTGCTTGAATACGCGACAGTTGGCTACATGTCGAAGAGGATACAGATGCGCAAGCAACGGTTCATTACCATACAAAAGATTATGGCCGAGAAGAAGATGCCCACGGAGTGTCCCCCGCCGTGGGACCCGCACACGCTCGCTAAAATGAGCTCCTTAAACCGCTACCCTCCTGGTAGCAGAGCTTCCGTGAGTAGAAGTTCGCAGGAAGTTCGCTACAAGGTCCGAGATCCGAAAGCGCACTCTAAGGGCGGCACGCTTGAGAACACGATCAGCAGGAGCAGGATGAACATCGAGGGGGACGCGGCGGGGCCCGTCATGCACCCCCTGCACCCGGGGAAGGACATTGGAAAATTCCTCGGCATGACGCCCTCGGACATCGACAAGTACTCGAGGATCGTGTTCCCGGTGTGCTTCGTCTGTTTCAACCTGGTCTACTGGATCGTGTACCTCCACGTGTCCGACGTGGTCGCCGAGGACCTGGAACTGCTCGAGGACAAGTGA

Protein

MSAVRHAALLLALAATFLPQANRVAGGGGGGMFGDVNISAILDSFSISYDKRVRPNYGGPPVEVGVTMYVLSISSVSEVLMDFTLDFYFRQFWTDPRLAYKKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRIHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYKWNEGPNSVGVSKEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVQLGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFTSLLEYATVGYMSKRIQMRKQRFITIQKIMAEKKMPTECPPPWDPHTLAKMSSLNRYPPGSRASVSRSSQEVRYKVRDPKAHSKGGTLENTISRSRMNIEGDAAGPVMHPLHPGKDIGKFLGMTPSDIDKYSRIVFPVCFVCFNLVYWIVYLHVSDVVAEDLELLEDK

Similarity

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

E0X9I2   E0X9I4   E0X9I1   H9JVX7   E0X9I3   A0A3G1J4Z2   + More
O18471   A0A2S0DGE1   E0X9I5   A0A1Q2T844   A0A0U5ACA3   U3TMA1   E0X9H7   A5A2M7   C0L7I4   A0A2H1WJ59   A9LYI3   C0L7I5   A0A3S2NX06   A0A1Q2T857   A0A2A4JF95   E0X9H8   E0X9H9   C0L956   A1Z0K6   A3FBG6   C0L955   A0A1Q2T851   G8IIS8   O18468   V9ZCF2   V9Z984   Q9XZW0   A5JJ42   A0A1Q2T839   A0A2A4JFC5   A0A1X9PRB2   H3JU08   A0A2J7QNV6   A8DMU0   A0A1W4WF43   M9Z6B1   A0A1W4WE60   A0A168SJQ0   A0A1I9VT68   E2IKR3   A8DMU1   A0A087Z8M8   G8IIR9   A0A168SJP2   A0A1Q2T841   A0A1I8JSK2   Q0GQR7   A0A182QGF5   A0A1W4W3J7   A0A1W4WE55   A0A182XM21   A0A182URJ2   A0A1Y9GKS7   A7UU05   A0A1Y9HEH3   A0A182J2V0   A0A158NFE0   A0A2H4WAU8   A0A0B5EEN9   A0A1I8QEE6   A0A168SJJ0   X5C002   X5BIT8   A0A1Y9H213   A0A1Y9IVD6   A0A1I8QEJ2   A0A0Q9WTB8   A0A2A4JL08   A0A2J7QNV0   A0A0K8STF5   A0A0K8TDA0   C0L7I6   A0A1Q2T840   A0A1J1J944   B4LHG7   A0A0Q9WHF3   F5C3U5   A0A1I8QED8   A0A0Q9WGK3   A0A2W1BQH7   A0A1I8QEF2   C0L7I7   A0A2J7QNV2   A8DMT9   A0A0M4EK86   A0A1B6DGU4   K7ZRK2   O17145   A0A0Q9XB93   A0A1W4WFF3   A0A0Q9WH84   B4KWM3   A0A1Q2T843   A0A1I8M4J7  

Pubmed

20924418    19121390    29408355    20513056    23909412    24365472    + More
10212398    17880682    18362917    19820115    27288983    26296809    20920257    16902773    12364791    14747013    17210077    21347285    29183375    17994087    21501685    28756777    23156177    18057021    25315136   

EMBL

GQ890666    ADM88011.1    GQ890668    ADM88013.1    GQ890665    ADM88010.1    + More
BABH01040612    GQ890667    ADM88012.1    KX856966    ASY91958.1    AF006192    AAB62572.1    KX856969    ASY91961.1    GQ890669    ADM88014.1    LC171477    BAW87784.1    AB278155    BAT57340.1    AB847423    BAN92442.1    GQ890661    ADM88006.1    EF521821    ABP96889.1    FJ665607    ACN52597.1    ODYU01009008    SOQ53088.1    EU273945    ABX47168.1    FJ665608    ACN52598.1    RSAL01000121    RVE46688.1    LC171476    BAW87783.1    NWSH01001799    PCG70103.1    GQ890662    ADM88007.1    GQ890663    ADM88008.1    FJ668709    ACN53549.1    EF156251    ABL86443.1    EF368369    ABN13426.1    ACN53550.1    LC171475    BAW87782.1    JN794059    AER59668.1    AF006189    AAB62563.1    KF881790    AHE41087.1    KF881791    AHE41088.1    AJ224513    CAB41615.1    EF535530    ABQ45398.1    LC171472    BAW87779.1    PCG70102.1    KY072798    ARO86294.1    AB617631    BAL63029.1    NEVH01012562    PNF30266.1    EF545117    KQ972204    ABU63595.1    KYB24596.1    KC841916    AGK30293.1    KU201323    ANC68178.1    KX431144    APA16887.1    HM566200    KX856970    ADK74004.1    ASY91962.1    EF545118    ABU63596.1    KYB24597.1    JN792582    AER59667.1    KU201322    ANC68177.1    LC171474    BAW87781.1    DQ667182    ABG75734.1    AXCN02000404    APCN01000072    APCN01000073    AAAB01008960    EDO63781.1    ADTU01014314    ADTU01014315    ADTU01014316    ADTU01014317    ADTU01014318    ADTU01014319    ADTU01014320    ADTU01014321    MG190358    AUC64171.1    KJ485710    AJE68941.1    KU201321    ANC68176.1    KJ174465    AHW29555.1    KJ174466    AHW29556.1    CH940647    KRF83883.1    NWSH01001075    PCG72737.1    PNF30265.1    GBRD01009258    JAG56563.1    GBRD01002284    JAG63537.1    FJ665609    ACN52599.1    LC171471    BAW87778.1    CVRI01000075    CRL08578.1    EDW68497.2    KRF83882.1    JF460792    AEB60992.1    KRF83884.1    KZ149977    PZC75884.1    FJ665610    ACN52600.1    PNF30267.1    EF545116    ABU63594.1    EFA12941.2    CP012525    ALC43610.1    GEDC01012391    JAS24907.1    AB697765    BAM66322.1    AF024647    AAB81966.1    CH933809    KRG05565.1    KRF83878.1    KRF83879.1    KRF83880.1    KRF83881.1    EDW17470.2    LC171473    BAW87780.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000235965    UP000007266    UP000192223    + More
UP000069272    UP000075886    UP000076407    UP000075903    UP000075840    UP000007062    UP000075900    UP000075880    UP000005205    UP000095300    UP000075884    UP000075920    UP000008792    UP000183832    UP000092553    UP000009192    UP000095301   

PRIDE

E0X9I2    E0X9I4    E0X9I1    H9JVX7    E0X9I3    E0X9I5    + More
U3TMA1    E0X9H7    A5A2M7    E0X9H8    E0X9H9   

Pfam

PF02932   Neur_chan_memb        + More
PF02931   Neur_chan_LBD

Interpro

IPR002289   GABAAb_rcpt        + More
IPR036734   Neur_chan_lig-bd_sf       
IPR006029   Neurotrans-gated_channel_TM       
IPR006202   Neur_chan_lig-bd       
IPR006028   GABAA/Glycine_rcpt       
IPR036719   Neuro-gated_channel_TM_sf       
IPR018000   Neurotransmitter_ion_chnl_CS       
IPR006201   Neur_channel       

SUPFAM

SSF90112   SSF90112        + More
SSF63712   SSF63712       

Gene 3D

2.70.170.10    

ProteinModelPortal

E0X9I2   E0X9I4   E0X9I1   H9JVX7   E0X9I3   A0A3G1J4Z2   + More
O18471   A0A2S0DGE1   E0X9I5   A0A1Q2T844   A0A0U5ACA3   U3TMA1   E0X9H7   A5A2M7   C0L7I4   A0A2H1WJ59   A9LYI3   C0L7I5   A0A3S2NX06   A0A1Q2T857   A0A2A4JF95   E0X9H8   E0X9H9   C0L956   A1Z0K6   A3FBG6   C0L955   A0A1Q2T851   G8IIS8   O18468   V9ZCF2   V9Z984   Q9XZW0   A5JJ42   A0A1Q2T839   A0A2A4JFC5   A0A1X9PRB2   H3JU08   A0A2J7QNV6   A8DMU0   A0A1W4WF43   M9Z6B1   A0A1W4WE60   A0A168SJQ0   A0A1I9VT68   E2IKR3   A8DMU1   A0A087Z8M8   G8IIR9   A0A168SJP2   A0A1Q2T841   A0A1I8JSK2   Q0GQR7   A0A182QGF5   A0A1W4W3J7   A0A1W4WE55   A0A182XM21   A0A182URJ2   A0A1Y9GKS7   A7UU05   A0A1Y9HEH3   A0A182J2V0   A0A158NFE0   A0A2H4WAU8   A0A0B5EEN9   A0A1I8QEE6   A0A168SJJ0   X5C002   X5BIT8   A0A1Y9H213   A0A1Y9IVD6   A0A1I8QEJ2   A0A0Q9WTB8   A0A2A4JL08   A0A2J7QNV0   A0A0K8STF5   A0A0K8TDA0   C0L7I6   A0A1Q2T840   A0A1J1J944   B4LHG7   A0A0Q9WHF3   F5C3U5   A0A1I8QED8   A0A0Q9WGK3   A0A2W1BQH7   A0A1I8QEF2   C0L7I7   A0A2J7QNV2   A8DMT9   A0A0M4EK86   A0A1B6DGU4   K7ZRK2   O17145   A0A0Q9XB93   A0A1W4WFF3   A0A0Q9WH84   B4KWM3   A0A1Q2T843   A0A1I8M4J7  

PDB

6I53     E-value=3.41857e-78,     Score=743

KEGG

100500925    no KO assigned | (RefSeq) ionotropic GABA-aminobutyric acid receptor RDL3

GO

GO:0005230   GO:0016021   GO:0004890   GO:0005886   GO:0006811   GO:0034220   GO:0007268   GO:0050877   GO:0007165   GO:0042391   GO:0043005   GO:0005887   GO:0045202   GO:0006810   GO:0016020   GO:0005216   GO:0043564   GO:0006418   GO:0003824   GO:0004888  

PANTHER

PTHR18945  

SignalP

Position:   1 - 26,         Likelihood:  0.968734

 

 

Length:

489

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

89.21974

Exp number, first 60 AAs:

2.40561

Total prob of N-in:

0.14808

outside

1  -  247

TMhelix

248  -  270

inside

271  -  278

TMhelix

279  -  301

outside

302  -  310

TMhelix

311  -  333

inside

334  -  452

TMhelix

453  -  475

outside

476  -  489

 

 

Pi

170.237433

Theta

156.691549

Tajima's D

0.37008

CLR

0.422128

CSRT

0.47607619619019

Interpretation

Uncertain