Gene

KWMTBOMO11820

Pre Gene Modal

BGIBMGA013689

Annotation

PREDICTED:_facilitated_trehalose_transporter_Tret1-like_[Amyelois_transitella]

Location

Bomo_Chr20(-):1091185-1095026      View in EpiBrowser

Full name

ADP-ribosylation factor-like protein 6      

Location in the cell

Cytoplasmic   Reliability : 1.152 Mitochondrial   Reliability : 1.734

CDS

ATGGAAGTAACTGTTCTGGTGCTGGGCTTGGACAACAGCGGGAAGAGTACGATGCTGAACACCTTGCGCCCTCCTGAGCAAAGAGCGCAGCATTTAATGCCAACCGTTGCACAGAACCATGATAGTTTTCAAAGTGGCGGAGTTAGTTTCACGGCTTGGGATGTGTCGGGGGCGCCGCGGCACCGCGCGCTGTGGGAGAGACATTACCGTCGAGCGCACGCCGTCATATTCGTCGTGGACTCCGCCGATCATCTTAGATTGGCTCGCGAGGAGCTGGAGCTCATGCTGGCTCATCCGGACATGTGCGGTCGGCGCATTCCCTTACTGGTGTTCGCGAATAAATGCGACGCGCCGCACGCACTCGCACCCATGCAGATTGCTGCAGTTTTAGGTCTAGAGCGTATCACGGACAAGCCGTGGCACGTGTGCGCGTCCATTGCGCTCTCCGGGGCTGGACTGGCGGACGGCGTGGCGTGGCTCGCCAGACAGATCCGCGACGCACATCTGCCCAAAAGTTAG

Protein

MEVTVLVLGLDNSGKSTMLNTLRPPEQRAQHLMPTVAQNHDSFQSGGVSFTAWDVSGAPRHRALWERHYRRAHAVIFVVDSADHLRLAREELELMLAHPDMCGRRIPLLVFANKCDAPHALAPMQIAAVLGLERITDKPWHVCASIALSGAGLADGVAWLARQIRDAHLPKS

Description

Probably involved in membrane protein trafficking at the base of the ciliary organelle. May function in cilia biogenesis. Isoform 2 is required for proper retinal function and organization.

Similarity

Belongs to the small GTPase superfamily. Arf family.

Keywords

Alternative splicing   Cell membrane   Cell projection   Cilium   Complete proteome   Cytoplasm   Cytoskeleton   GTP-binding   Lipoprotein   Magnesium   Membrane   Metal-binding   Myristate   Nucleotide-binding   Reference proteome   Sensory transduction   Vision  

Feature

chain  ADP-ribosylation factor-like protein 6
splice variant  In isoform 2.

Uniprot

H9JVX6   A0A2A4J7F5   A0A139WED1   A0A0N1ICY5   A0A1Y1LB87   A0A1S4F1D9   + More
A0A1D2NCZ6   A0A2J7PLJ4   A0A1S3PP35   A0A1B0DJK9   A0A067RIH6   A0A3Q4GAP9   A0A3Q2V3H2   A0A3P8QJW5   A0A3P9BWC9   T1IP28   A0A182W1X0   A0A182JSJ9   A0A212EXU4   A0A1S4HEX4   A0A158N7M7   A0A182XGR9   A0A182N3V8   A0A182V8G3   A0A182L4W0   A0A182TVD2   A0A182HHD6   A0A182S540   A0A182QWC9   A0A182MX85   A0A2T7NTD9   A0A315W600   A0A1S3PQ80   H3B9Z9   A0A3Q2ZS56   A0A3Q2E7Q2   A0A3Q0QSI7   A0A087ULK2   A0A3B4WE96   A0A3B1K1D9   A0A2P6L312   H2V4M9   A0A3Q1C1R6   A0A3P8TTB7   A0A3P8ZDQ3   A0A3Q1H550   A0A146VJ95   A0A3B3DRL0   G3PRP6   A0A3Q2D334   M3ZML1   A0A3B4D2Q2   A0A0P4WE42   B2GRI2   Q5M9P8   A0A3Q3KRE1   R7V0W7   A0A3P9IWK5   A0A3B5AZJ1   H2LK30   A0A3P9HZN2   A0A3P8TUH7   A0A3B1IQ84   A0A3Q3EEE7   A0A0T6BAB5   A0A3P8T119   H2MLE0   A0A183UWD8   A0A1S4E9T8   A0A3P8ZDQ8   A0A3Q1H3E7   A0A0N1IQE1   A0A3B3DQ14   A0A2U9BBV3   H3CVL6   A0A1S3MV37   A0A3B3HV64   A0A3B4EHJ4   A0A3P9L1C8   A0A3Q3EED1   A0A146NGC2   A0A3Q3RL32   A0A0M8ZXL4   A0A1W4ZE54   G1TLB3   Q5M9P8-2   A0A1U7U2P1   A0A2L2YW94   I3J4U1   A0A1A8NC40   A0A1A8JFI6   A0A2I4ASN3   I3NC55   A0A3P8R3E3   A0A3P9B0A7   A0A3B3QEE0   A0A3R7LP64   A0A3P9LQD9   A0A336LUH0   A0A3B3E1X7  

Pubmed

19121390    18362917    19820115    26354079    28004739    27289101    + More
24845553    25186727    22118469    12364791    20920257    20966253    29703783    9215903    25329095    21551351    25069045    29451363    23542700    23594743    20333246    23254933    17554307    15496914    21993624    26561354    29240929   

EMBL

BABH01040609    NWSH01002628    PCG67809.1    KQ971354    KYB26338.1    KQ459718    + More
KPJ20250.1    GEZM01064137    JAV68826.1    LJIJ01000086    ODN03122.1    NEVH01024425    PNF17202.1    AJVK01015826    KK852661    KDR19093.1    JH431242    AGBW02011687    OWR46305.1    AAAB01008986    GGFL01004796    MBW68974.1    APCN01002407    AXCN02001095    AXCM01000489    PZQS01000009    PVD24406.1    NHOQ01000293    PWA31134.1    AFYH01037412    AFYH01037413    AFYH01037414    AFYH01037415    AFYH01037416    KK120417    KFM78241.1    MWRG01002188    PRD32966.1    GCES01069316    JAR17007.1    GDRN01044647    JAI66909.1    BC165137    AAI65137.1    BX901972    BC086734    AMQN01005508    KB296162    ELU12137.1    LJIG01002660    KRT84280.1    UYWY01021437    VDM44129.1    LADI01012895    KPJ20756.1    CP026247    AWP01432.1    AWP01433.1    GCES01156236    GCES01002868    JAQ30086.1    KQ435824    KOX72146.1    AAGW02016284    IAAA01062754    LAA12354.1    AERX01013868    HAEH01001306    HAEI01014964    SBR66633.1    HAED01021955    HAEE01001843    SBR08708.1    AGTP01090175    AGTP01090176    QCYY01004634    ROT60684.1    UFQT01000195    SSX21500.1   

Proteomes

UP000005204    UP000218220    UP000007266    UP000053240    UP000094527    UP000235965    + More
UP000087266    UP000092462    UP000027135    UP000261580    UP000264840    UP000265100    UP000265160    UP000075920    UP000075881    UP000007151    UP000076407    UP000075884    UP000075903    UP000075882    UP000075902    UP000075840    UP000075900    UP000075886    UP000075883    UP000245119    UP000008672    UP000264800    UP000265020    UP000261340    UP000054359    UP000261360    UP000018467    UP000005226    UP000257160    UP000265080    UP000265140    UP000257200    UP000261560    UP000007635    UP000002852    UP000261440    UP000000437    UP000261640    UP000014760    UP000265200    UP000261400    UP000001038    UP000265180    UP000050794    UP000267007    UP000079169    UP000265040    UP000053268    UP000246464    UP000007303    UP000265000    UP000053105    UP000192224    UP000001811    UP000189704    UP000005207    UP000192220    UP000005215    UP000261540    UP000283509   

PRIDE

H9JVX6   

Pfam

PF00025   Arf        + More
PF15061   DUF4538
PF00083   Sugar_tr

Interpro

IPR027417   P-loop_NTPase        + More
IPR005225   Small_GTP-bd_dom       
IPR006689   Small_GTPase_ARF/SAR       
IPR041839   Arl6       
IPR027917   SMIM20       
IPR020846   MFS_dom       
IPR005829   Sugar_transporter_CS       
IPR036259   MFS_trans_sf       
IPR005828   MFS_sugar_transport-like       

SUPFAM

SSF52540   SSF52540        + More
SSF103473   SSF103473       

CDD

cd04157  Arl6
cd06174  MFS

ProteinModelPortal

H9JVX6   A0A2A4J7F5   A0A139WED1   A0A0N1ICY5   A0A1Y1LB87   A0A1S4F1D9   + More
A0A1D2NCZ6   A0A2J7PLJ4   A0A1S3PP35   A0A1B0DJK9   A0A067RIH6   A0A3Q4GAP9   A0A3Q2V3H2   A0A3P8QJW5   A0A3P9BWC9   T1IP28   A0A182W1X0   A0A182JSJ9   A0A212EXU4   A0A1S4HEX4   A0A158N7M7   A0A182XGR9   A0A182N3V8   A0A182V8G3   A0A182L4W0   A0A182TVD2   A0A182HHD6   A0A182S540   A0A182QWC9   A0A182MX85   A0A2T7NTD9   A0A315W600   A0A1S3PQ80   H3B9Z9   A0A3Q2ZS56   A0A3Q2E7Q2   A0A3Q0QSI7   A0A087ULK2   A0A3B4WE96   A0A3B1K1D9   A0A2P6L312   H2V4M9   A0A3Q1C1R6   A0A3P8TTB7   A0A3P8ZDQ3   A0A3Q1H550   A0A146VJ95   A0A3B3DRL0   G3PRP6   A0A3Q2D334   M3ZML1   A0A3B4D2Q2   A0A0P4WE42   B2GRI2   Q5M9P8   A0A3Q3KRE1   R7V0W7   A0A3P9IWK5   A0A3B5AZJ1   H2LK30   A0A3P9HZN2   A0A3P8TUH7   A0A3B1IQ84   A0A3Q3EEE7   A0A0T6BAB5   A0A3P8T119   H2MLE0   A0A183UWD8   A0A1S4E9T8   A0A3P8ZDQ8   A0A3Q1H3E7   A0A0N1IQE1   A0A3B3DQ14   A0A2U9BBV3   H3CVL6   A0A1S3MV37   A0A3B3HV64   A0A3B4EHJ4   A0A3P9L1C8   A0A3Q3EED1   A0A146NGC2   A0A3Q3RL32   A0A0M8ZXL4   A0A1W4ZE54   G1TLB3   Q5M9P8-2   A0A1U7U2P1   A0A2L2YW94   I3J4U1   A0A1A8NC40   A0A1A8JFI6   A0A2I4ASN3   I3NC55   A0A3P8R3E3   A0A3P9B0A7   A0A3B3QEE0   A0A3R7LP64   A0A3P9LQD9   A0A336LUH0   A0A3B3E1X7  

PDB

2H57     E-value=4.40201e-41,     Score=417

KEGG

101743361    K07951 ADP-ribosylation factor-like protein 6 | (RefSeq) ADP-ribosylation factor-like protein 6

GO

GO:0005525   GO:0006886   GO:0005930   GO:0060271   GO:0061512   GO:0016192   GO:0005737   GO:0033617   GO:0005739   GO:0016021   GO:0022857   GO:0007601   GO:0007369   GO:0032402   GO:0007368   GO:0005623   GO:0008593   GO:0033339   GO:0070121   GO:0046872   GO:0060170   GO:0050896   GO:0010842   GO:0097499   GO:0016055   GO:0045444   GO:0016020   GO:0005929   GO:0007420   GO:0008589   GO:0005829   GO:1903445   GO:0005622   GO:0007264   GO:0008270   GO:0005524   GO:0006139   GO:0019205   GO:0043564   GO:0006418   GO:0003824  

Subcellular location

Cell projection  
Cilium membrane  
Cytoplasm  
Cytoskeleton  
Cilium axoneme  
Cilium basal body  

Length:

172

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.6665

Exp number, first 60 AAs:

0.00088

Total prob of N-in:

0.02453

outside

1  -  172

 

 

Pi

257.409269

Theta

178.009858

Tajima's D

1.348503

CLR

0.094305

CSRT

0.751762411879406

Interpretation

Uncertain