Gene

KWMTBOMO11794

Pre Gene Modal

BGIBMGA013650

Annotation

PREDICTED:_trypsin-like_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr20(-):147278-150403      View in EpiBrowser

Full name

Trypsin      

Location in the cell

Nuclear   Reliability : 1.387 PlasmaMembrane   Reliability : 1.926

CDS

ATGTATTCATTTAATGCTCTTGCTTATCTCCTCACGTTCAGCATGCCCTCTCAATTGAGAAAACTATTTAACTTGATACTGACCACCTTTATTATTGTAACGGCATCTTCAGATTCAGACTCACGAGAGGAACATAGCTCAGAAAACCAAGAATATAATGAAGTATTTAATCTCAGCTTAAAAGAAAAACCCAAGAGAACTAGGCAAGAGCAGCACCAGTGCTTTAATGCTGAAACTTCTTCTGAGATTACGAATAAACCTCAGTGCGGTTACCAGGATCACATAAGTACCGAGAAGCGAGCTAAAGACGAAAGTACTTTAAGCAGATATCCTTTTTCCGCCTCTATACAAAGAAAGGGAGCACATTACGCTACAGGTGCTCTTCTTAACAAAAGATGGATCCTGAGTTCAGCTGGAGAGTTTTATAATGTGAGGGAATCAATAAAACTATTTAAGGTGAGATTAGGCTCAAGTGATTGCAAAAGAGGCGGTGTTTTAATACCAATAAGGGGGTTGGTGATTCACCCGTCTTACATTTTTGGTAAACCAAGCTTCGACCTGGCAATGCTGAAAATAGCAGTCCCCGTTAATTATTCTCCAGCCATCAGGCCGGTCAGGCTATCGAAGGTCACAGCTAAACTCTTGGATGCCAACTTCCTAACGACCTATTGGCCTAGGATCATAATCAAAGGTCGAACGATATCTCCGTCGGCGAGCGAGCGCACAAGGCCGAGCAGCATGAGGGTGTCCACGCAGAGCACCGTACCCCGCGAGGACTGCGAGGAACTCATGGAGGAGCAGAACGAAACGCTCGGAGGAGACAGCTTTTGTCTGAAGCCGGTTGGCGGACACCACAGCGCTTGCAGCCCGGACGTCGGCGCGCCAGTTATTGCAAATGACGGACTTTGGGGCATCACGTCGGGATGGACGTCGAGGGACTGCGAGCGGAATGAAAGTCCCACAATAATAACACGCACCTCCTCGTCGGGCATGCGCGCCTGGTTAGACGAACAGCTGTTGGATACTTAA

Protein

MYSFNALAYLLTFSMPSQLRKLFNLILTTFIIVTASSDSDSREEHSSENQEYNEVFNLSLKEKPKRTRQEQHQCFNAETSSEITNKPQCGYQDHISTEKRAKDESTLSRYPFSASIQRKGAHYATGALLNKRWILSSAGEFYNVRESIKLFKVRLGSSDCKRGGVLIPIRGLVIHPSYIFGKPSFDLAMLKIAVPVNYSPAIRPVRLSKVTAKLLDANFLTTYWPRIIIKGRTISPSASERTRPSSMRVSTQSTVPREDCEELMEEQNETLGGDSFCLKPVGGHHSACSPDVGAPVIANDGLWGITSGWTSRDCERNESPTIITRTSSSGMRAWLDEQLLDT

Catalytic Activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Digestion   Disulfide bond   Glycoprotein   Hydrolase   Protease   Secreted   Serine protease   Signal   Zymogen  

Feature

propeptide  Activation peptide
chain  Trypsin

Uniprot

A0A2A4JYQ1   A0A2H1W6G0   A0A0N1IQB1   A0A194Q5E2   A0A3S2L7J7   A0A0L7L4N4   + More
A0A2W1BWP4   A0A2H1W522   A0A2A4IWZ1   A0A1L9T475   A0A1L9PUE2   O97399   A0A195EDZ4   A0A158NDD6   A0A194Q6Y3   A0A195F7K8   A0A195B099   A0A2W1BPS3   A0A195EUU2   A0A084VY03   A0A2A4K063   A0A034WYC1   E9IJV0   A0A2A4K0I2   A0A0K8UU41   A0A212F0N0   A0A2H1X0F7   A0A0A1WJ19   A0A2C9GTP2   A0A0M4E9T2   A0A034WPI6   A0A1B0D1R8   O02570   G3NYA9  

EC Number

3.4.21.4

Pubmed

26354079    26227816    28756777    28196534    10612046    21347285    + More
24438588    25348373    21282665    22118469    25830018    20966253   

EMBL

NWSH01000350    PCG77151.1    ODYU01006643    SOQ48670.1    KQ459838    KPJ19753.1    + More
KQ459460    KPJ00763.1    RSAL01001561    RVE40760.1    JTDY01002946    KOB70432.1    KZ149924    PZC77617.1    ODYU01006381    SOQ48179.1    NWSH01005274    PCG64325.1    KV878595    OJJ54227.1    KV878132    OJJ05180.1    Y17905    CAA76929.1    KQ979074    KYN23022.1    ADTU01012123    ADTU01012124    KPJ00760.1    KQ981744    KYN36366.1    KQ976692    KYM77715.1    KZ149937    PZC77042.1    KQ981958    KYN32013.1    ATLV01018235    KE525226    KFB42847.1    PCG77153.1    GAKP01000184    JAC58768.1    GL763883    EFZ19174.1    PCG77152.1    GDHF01022105    JAI30209.1    AGBW02011050    OWR47306.1    ODYU01012498    SOQ58840.1    GBXI01015228    JAC99063.1    CP012523    ALC39026.1    GAKP01003294    JAC55658.1    AJVK01022275    U65412    AAB37261.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000283053    UP000037510    UP000184356    + More
UP000184073    UP000078492    UP000005205    UP000078541    UP000078540    UP000030765    UP000007151    UP000075882    UP000092553    UP000092462    UP000007635   

Pfam

PF00089   Trypsin        + More
PF03134   TB2_DP1_HVA22

Interpro

IPR001254   Trypsin_dom        + More
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR018114   TRYPSIN_HIS       
IPR033116   TRYPSIN_SER       
IPR012224   Pept_S1A_FX       
IPR004345   TB2_DP1_HVA22       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

A0A2A4JYQ1   A0A2H1W6G0   A0A0N1IQB1   A0A194Q5E2   A0A3S2L7J7   A0A0L7L4N4   + More
A0A2W1BWP4   A0A2H1W522   A0A2A4IWZ1   A0A1L9T475   A0A1L9PUE2   O97399   A0A195EDZ4   A0A158NDD6   A0A194Q6Y3   A0A195F7K8   A0A195B099   A0A2W1BPS3   A0A195EUU2   A0A084VY03   A0A2A4K063   A0A034WYC1   E9IJV0   A0A2A4K0I2   A0A0K8UU41   A0A212F0N0   A0A2H1X0F7   A0A0A1WJ19   A0A2C9GTP2   A0A0M4E9T2   A0A034WPI6   A0A1B0D1R8   O02570   G3NYA9  

PDB

3DFL     E-value=1.1669e-12,     Score=176

KEGG

101736362    no KO assigned | (RefSeq) trypsin-like

GO

GO:0004252   GO:0007586   GO:0005576   GO:0005509   GO:0007596   GO:0016021   GO:0006508   GO:0022857   GO:0005524   GO:0006139   GO:0019205   GO:0043564   GO:0006418   GO:0003824  

Subcellular location

Secreted  

Length:

342

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.247030000000001

Exp number, first 60 AAs:

0.22986

Total prob of N-in:

0.01878

outside

1  -  342

 

 

Pi

302.059672

Theta

196.147847

Tajima's D

1.965181

CLR

0.171508

CSRT

0.874806259687016

Interpretation

Uncertain