SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO11748  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA004157
Annotation
1607133A_egg_specific_protein
Location
Bomo_Chr19(-):13191643-13193483      View in EpiBrowser
Full name
Lipase      
Location in the cell
Nuclear   Reliability : 3.307
 

Sequence

CDS
ATGAAGACTATATACGCATTGCTGTGTCTGACGCTGGTGCAGAGCATCTCCTGCAGCATCTTCATGACGAAACAACACAGTCAGGATGACATCATTCAACACCCTCTGGACTATGTCGAACAGCAGATCCATCAGCAGAAACAAAAACTACACAAGCAAACCTTGAACAAGAGGAGCCACCAGCACTCTGATTCGGATTCGGATTCGGCGTCTCGTGCGGCGGCGTCACATTCAGCCTCCCAATCGTCGAGTTCACAAAGCTCCAGTTCACAAGAGGATGAAACTAAGCAGGTGCACGATAAGATGAACGTGAAACACCACTCGCCGGTGTATTCTGTCATTATGAAACTCAAGAAAGAAGTTGATATCAATCACGGCGATTCCGTCGTTTGGAAGAATATAGAAATGGCCTCCGGCCCTAACTCGCCGGTTCAGACAGAGCAAGATATTGAGGATATTTTCGGTGACTCCCTAAAGACGTGGGATCATTTCACTGACGATGCAAAGAAAAATACCTTCCACGACGCTATCAGTGAAACTCAAAGGGAAAACAATGAGGACTTCCACCTAAACGCTACTGAGCTGCTCAAGAAACATCAATACCCCGTAGAAGAACACACGGTCGCCACCGACGACGGCTACCATTTGACTGTCCTGCGCATTCCACCCACGCACCAAACCAGGGACGATAAGAAGAAGCCGGTCGCGCTTCTAATGCACGGCTTACTCGGAAGCGCTGACGACTGGTTACTGATGGGTCCCAGTAAGTCACTCGCTTACATGCTCTGTGACGCCGGCTACGACGTATGGCTGGGTAATGTTCGTGGAAACAAATATTCCCGCTCTCACGTCAGCAAGCACCCAGCACTCAATGACTTCTGGAAGTTTAGCAATGACGAGATCGCTCTTCACGACTTACCCGCTATAATTGACCACGTTTTGGATATTAGCGGCCAAGAGAGACTTCATTACATAGGCCATTCTCAAGGCGCGACCACCTTCTTCGCCCTGATGTCCGAACAGCCTTCGTACAACGAAAAGATCGTTTCGATGCACGCGTTGTCTCCTATTGTTTACATGAATTATGTACGCTCGCCCCTCTTCCGTATGATCGCGCCCACGAGCAAGTTCTACCAGTATATACACGACCAAGTCGGTCACGGAGCCTTCGAACCTGGCAAACACCTGATCGAAACCTTCGGCGGCGCCGCGTGCAGGGAAAAACTCGGTTGCAGACACGTCTGTAACAACTTGAACTACGTCATATCGGGTATCAACGTTTACAACCAGGATGCGGATATAGTTCCCGTTGTGATGGCCCACCTGCCAGCCGGCACATCCGCCCGGGTCATGAAACAATACGGTCAGAATGTGGCGTCGCACGATTTTAGAAAATACAACTACGGAGCAGAAACCAACATGAAAGTGTACGGCACTTCGGAACCACCTAGTTACGACTTGAGCAAAGTCAGCGCGCCTGTCAATCTTTACCACAGCCACGATGCCTGGTTGGCCCATCCCAAGGACGTGGAGAAACTCCAAGAAAACCTGCCTAATGTGAAGCAGTCTTTCGAAGTTCCAGAGCAACAACACTTCACGGACCTGGACTTCCAATTCTCGAAGAAAGCCCCCGATACCGTATACCAGAAACTGATGGAAAACATGCAGAATAACTCATAA
Protein
MKTIYALLCLTLVQSISCSIFMTKQHSQDDIIQHPLDYVEQQIHQQKQKLHKQTLNKRSHQHSDSDSDSASRAAASHSASQSSSSQSSSSQEDETKQVHDKMNVKHHSPVYSVIMKLKKEVDINHGDSVVWKNIEMASGPNSPVQTEQDIEDIFGDSLKTWDHFTDDAKKNTFHDAISETQRENNEDFHLNATELLKKHQYPVEEHTVATDDGYHLTVLRIPPTHQTRDDKKKPVALLMHGLLGSADDWLLMGPSKSLAYMLCDAGYDVWLGNVRGNKYSRSHVSKHPALNDFWKFSNDEIALHDLPAIIDHVLDISGQERLHYIGHSQGATTFFALMSEQPSYNEKIVSMHALSPIVYMNYVRSPLFRMIAPTSKFYQYIHDQVGHGAFEPGKHLIETFGGAACREKLGCRHVCNNLNYVISGINVYNQDADIVPVVMAHLPAGTSARVMKQYGQNVASHDFRKYNYGAETNMKVYGTSEPPSYDLSKVSAPVNLYHSHDAWLAHPKDVEKLQENLPNVKQSFEVPEQQHFTDLDFQFSKKAPDTVYQKLMENMQNNS

Summary

Similarity
Belongs to the AB hydrolase superfamily. Lipase family.
Feature
chain  Lipase
Uniprot
H9J3S0   Q17219   A0A2A4K549   A0A2W1BHK8   A0A0L7LE30   A0A2H1VV71   + More
A0A194PNG5   A0A194QY62   A0A343EU28   C7B189   O77107   Q86M39   Q94568   A0A194R2Y3   A0A2W1BS78   A0A194QUC1   A0A194QQB7   A0A1Y1KBU1   A0A212FB51   U5ERJ2   A0A212FG21  
Pubmed
19121390    28756777    26227816    26354079    19564928    9880901    + More
28004739    22118469   
EMBL
BABH01028866    D12521    BAA02091.1    NWSH01000119    PCG79375.1    KZ150162    + More
PZC72687.1    JTDY01001496    KOB73732.1    ODYU01004598    SOQ44646.1    KQ459598    KPI94528.1    KQ460949    KPJ10407.1    MF067302    ASM61899.1    FJ744151    ACT53735.1    AF063014    AAC62229.1    AB081090    BAC66969.1    U69881    AAB09081.1    KQ460855    KPJ11879.1    KZ149971    PZC76037.1    KQ461190    KPJ07151.1    KPJ07150.1    GEZM01086956    JAV58943.1    AGBW02009374    OWR50972.1    GANO01002781    JAB57090.1    AGBW02008724    OWR52685.1   
Proteomes
UP000005204    UP000218220    UP000037510    UP000053268    UP000053240    UP000007151    + More
PRIDE
H9J3S0    Q17219   
Pfam
PF04083   Abhydro_lipase        + More
PF00561   Abhydrolase_1
Interpro
IPR006693   AB_hydrolase_lipase        + More
IPR029058   AB_hydrolase       
IPR025483   Lipase_euk       
IPR000073   AB_hydrolase_1       
SUPFAM
SSF53474   SSF53474       
Gene 3D
3.40.50.1820    
ProteinModelPortal
H9J3S0   Q17219   A0A2A4K549   A0A2W1BHK8   A0A0L7LE30   A0A2H1VV71   + More
A0A194PNG5   A0A194QY62   A0A343EU28   C7B189   O77107   Q86M39   Q94568   A0A194R2Y3   A0A2W1BS78   A0A194QUC1   A0A194QQB7   A0A1Y1KBU1   A0A212FB51   U5ERJ2   A0A212FG21  
PDB
1K8Q     E-value=5.53725e-63,     Score=613

Ontologies

KEGG
693022    K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] | (RefSeq) egg-specific prote
PATHWAY
00100    Steroid biosynthesis - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)
GO
GO:0006629   GO:0016042   GO:0016788   GO:0006355   GO:0006396   GO:0005615   GO:0005524   GO:0006139   GO:0019205   GO:0043564   GO:0006418   GO:0003824  

Topology

SignalP
Position:   1 - 18,         Likelihood:  0.971661
 
 
Length:
559
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.590139999999999
Exp number, first 60 AAs:
0.56259
Total prob of N-in:
0.02869
outside
1  -  559
 
 

Population Genetic Test Statistics

Pi
15.795923
Theta
13.268648
Tajima's D
0.45648
CLR
3.51098
CSRT
0.514424278786061
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
31223520 FYQYIHDQVGHGAFEPGKHLIETFGGAACR 100.00 1e-19
31223520 LHYIGHSQGATTFFALMSEQPSYNEK 100.00 1e-19
31223520 LHYIGHSQGATTFFALMSEQPSYNEK 100.00 5e-17
31223520 NIEMASGPNSPVQTEQDIEDIFGDSLK 100.00 4e-12
31223520 KHQYPVEEHTVATDDGYHLTVLR 100.00 4e-12
31223520 KHQYPVEEHTVATDDGYHLTVLR 100.00 5e-12
31223520 QSFEVPEQQHFTDLDFQFSK 100.00 5e-12
31223520 FSNDEIALHDLPAIIDHVLDISGQER 100.00 6e-12
31223520 FSNDEIALHDLPAIIDHVLDISGQER 100.00 6e-12
31223520 QSFEVPEQQHFTDLDFQFSK 100.00 2e-11
31223520 KKPVALLMHGLLGSADDWLLMGPSK 100.00 6e-11
31223520 KKPVALLMHGLLGSADDWLLMGPSK 100.00 6e-11
31223520 HQYPVEEHTVATDDGYHLTVLR 100.00 8e-10
31223520 HQYPVEEHTVATDDGYHLTVLR 100.00 8e-10
31223520 KPVALLMHGLLGSADDWLLMGPSK 100.00 8e-10
31223520 SLAYMLSDAGYDVWLGNVR 100.00 4e-08
31223520 QSFEVPEQQHFTDLDFQFSK 100.00 4e-08
31223520 VSAPVNLYHSHDAWLAHPK 100.00 4e-07
31223520 IVSMHALSPIVYMNYVR 100.00 4e-07
31223520 VSAPVNLYHSHDAWLAHPK 100.00 4e-07
31223520 FYQYIHDQVGHGAFEPGK 100.00 5e-07
31223520 SLAYMLSDAGYDVWLGNVR 100.00 5e-07
31223520 IVSMHALSPIVYMNYVR 100.00 6e-07
31223520 VYGASEPPSYDLSK 100.00 6e-07
31223520 SHVSKHPALNDFWK 100.00 4e-05
31223520 KNTFHDAISETQR 100.00 4e-05
31223520 VSAPVNLYHSHDAWLAHPKDVEK 100.00 2e-04
31223520 KNTFHDAISETQR 100.00 3e-04
31223520 QYGQNVASHDFRK 100.00 0.001
31223520 QYGQNVASHDFR 100.00 0.005
31223520 VYGTSEPPSYDLSK 100.00 0.009
31223520 NTFHDAISETQR 100.00 0.012
31223520 QYGQNVASHDFR 100.00 0.012
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