Gene

KWMTBOMO11737  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004162

Annotation

PREDICTED:_ER_membrane_protein_complex_subunit_7_[Amyelois_transitella]

Location

Bomo_Chr19(-):13049574-13050323      View in EpiBrowser

Full name

RBR-type E3 ubiquitin transferase      

Location in the cell

Cytoplasmic   Reliability : 1.591 Nuclear   Reliability : 2.274

CDS

ATGAATACAAAAATCATCATAATATACATTTCGACATTCGTGCTCGGCAATGTTTATTGCGCTAGTGATCTGACTGAAGAAGAAATCGGACATGTTATCGAAGGCCGTGTGTTTCCTCCTGAAGATCCCAACAACAGCAATTGGCAATTGGACACCCGCGTTCACGTTAACGGAGGCGAATACATCGGTTTTGTCCGAGAAGATGGGACATTTGTGGTGCATAATTTACCGTCTGGTTCATACGTCGTCGAAATCGTACACCCAGACTACATGTACGAACCCGTGCGTGTCGAAATCAATTCTAAAGGCAAATACAGAGCTAGAAAAGTCAATTACGTTCAAACTTCACAAGTCATTCAAGTACCTTACCCGCTGAGGATGAAACCAGTCACCAAATTCAGATATTTTCAAGTTCGGGAACAATGGAGGCTCACTGACTTCTTGTTCAACCCAATGGTGGTAATGATGGTGCTACCATTATTCTTAATCATGATTCTACCTAAAATGATGAATGATCCTGAGACTAAAGAGGATTTGAAGCAGATAAGCAATCTGGCAAAAATATCTGATGTGCCGGAAATGTCAGAAATGTTTACTAAAATCTTCAATAGGGGTTCAGTGCCAAAACCAACGAGTTCTAAAGCTAAACAAATTAAGAAAAGACAATAG

Protein

MNTKIIIIYISTFVLGNVYCASDLTEEEIGHVIEGRVFPPEDPNNSNWQLDTRVHVNGGEYIGFVREDGTFVVHNLPSGSYVVEIVHPDYMYEPVRVEINSKGKYRARKVNYVQTSQVIQVPYPLRMKPVTKFRYFQVREQWRLTDFLFNPMVVMMVLPLFLIMILPKMMNDPETKEDLKQISNLAKISDVPEMSEMFTKIFNRGSVPKPTSSKAKQIKKRQ

Catalytic Activity

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.

Similarity

Belongs to the RBR family.

Feature

chain  RBR-type E3 ubiquitin transferase

Uniprot

H9J3S5   A0A1E1W412   A0A2W1BLY2   A0A2A4K544   A0A194QYQ1   A0A194PNH5   + More
A0A2H1VV04   A0A0L7LRK5   A0A212F3U7   A2IA77   E2BU45   K7IVQ9   A0A195F989   A0A026WRN8   A0A151WFG6   E9IET0   A0A195EAE0   F4WYW6   A0A151HZV2   A0A158NC77   B0WGQ0   T1PA78   V5GTB2   A0A182PSR5   A0A182IDH5   Q7Q7Q1   A0A1Q3FGS4   A0A182JVX4   A0A182REA0   A0A182XDR6   A0A182R081   A0A182VPS0   A0A182SJP1   A0A182YES2   A0A182MBI8   A0A182G2P4   A0A023EL35   A0A023EN45   Q16NH4   A0A2M4BYE6   A0A084W7X0   W5JWT6   A0A2M3Z7B3   A0A182J0X8   A0A182NE00   A0A1W4WJB0   A0A2M4AKI0   A0A2M4AL08   A0A0A1X7S3   A0A182FP49   J3JWP2   A0A182LNQ4   E0VD72   E2A1Q6   A0A2J7QFD5   A0A151IK28   A0A1I8QAU9   A0A1A9UI49   A0A1A9YUE3   A0A1Y1KJF1   A0A1L8EBV1   A0A1B0BGB0   A0A1A9XG18   A0A1A9Z5L5   A0A240SWE6   A0A1B6EB66   A0A0L7R4N6   A0A293LNH9   A0A310SC11   G3MPE5   A0A023FL78   A0A023GMQ3   A0A088ANN1   B7Q0N4   A0A067REF8   A0A0M8ZWR2   A0A154NYB5   A0A0K8RMC8   A0A131Y755   A0A336LID4   L7M4Q2   A0A131ZBN0   D6WR13   A0A1B6GED0   T1IA13   A0A1Z5L2I3   A0A1B6MTD0   T1JN94   A0A0P4W4E5   A0A1L8E755   A0A2P8ZJB1   A0A2H8THK5   S5MJX0   B4KQC0   C4WW17   A0A1L8E5T4   A0A1B0CU26   B4LL44   A0A0K8V0Y4   A0A0L0CDN3  

EC Number

2.3.2.31

Pubmed

19121390    28756777    26354079    26227816    22118469    17437641    + More
20798317    20075255    24508170    30249741    21282665    21719571    21347285    25315136    12364791    14747013    17210077    25244985    26483478    24945155    17510324    24438588    20920257    23761445    25830018    22516182    23537049    20966253    20566863    28004739    22216098    24845553    25576852    26830274    18362917    19820115    28528879    27129103    29403074    23851222    17994087    26108605   

EMBL

BABH01028856    GDQN01009341    JAT81713.1    KZ150162    PZC72693.1    NWSH01000119    + More
PCG79357.1    KQ460949    KPJ10419.1    KQ459598    KPI94538.1    ODYU01004598    SOQ44653.1    JTDY01000300    KOB77806.1    AGBW02010485    OWR48416.1    EF179391    ABM55397.1    GL450581    EFN80762.1    KQ981727    KYN37170.1    KK107119    QOIP01000009    EZA58710.1    RLU18461.1    KQ983211    KYQ46584.1    GL762690    EFZ20923.1    KQ979236    KYN22185.1    GL888463    EGI60620.1    KQ976642    KYM78671.1    ADTU01011672    DS231928    EDS27126.1    KA645681    AFP60310.1    GALX01003574    JAB64892.1    APCN01005979    AAAB01008952    EAA10592.4    GFDL01008287    JAV26758.1    AXCN02002212    AXCM01000238    JXUM01139843    KQ568963    KXJ68818.1    GAPW01003687    JAC09911.1    GAPW01003814    JAC09784.1    CH477824    EAT35888.1    EAT35889.1    GGFJ01008964    MBW58105.1    ATLV01021318    KE525316    KFB46314.1    ADMH02000156    ETN67549.1    GGFM01003665    MBW24416.1    GGFK01007943    MBW41264.1    GGFK01007977    MBW41298.1    GBXI01007341    JAD06951.1    APGK01058329    BT127660    KB741288    KB632322    AEE62622.1    ENN70674.1    ERL92336.1    DS235072    EEB11328.1    GL435766    EFN72729.1    NEVH01015299    PNF27297.1    KQ977258    KYN04626.1    CCAG010004750    GEZM01081655    JAV61562.1    GFDG01002766    JAV16033.1    JXJN01013815    GEDC01002119    JAS35179.1    KQ414657    KOC65818.1    GFWV01010328    MAA35057.1    KQ772267    OAD52456.1    JO843746    AEO35363.1    GBBK01001891    JAC22591.1    GBBM01000294    JAC35124.1    ABJB010382784    ABJB010886289    ABJB010909203    DS833226    EEC12406.1    KK852747    KDR17271.1    KQ435833    KOX71626.1    KQ434782    KZC04613.1    GADI01002154    JAA71654.1    GEFM01000727    JAP75069.1    UFQT01000016    SSX17802.1    GACK01006014    JAA59020.1    GEDV01000219    JAP88338.1    KQ971351    EFA06540.1    GECZ01008999    JAS60770.1    ACPB03012045    GFJQ02005749    JAW01221.1    GEBQ01000814    JAT39163.1    JH431244    GDKW01000381    JAI56214.1    GFDG01004241    JAV14558.1    PYGN01000038    PSN56581.1    GFXV01001716    MBW13521.1    KC480149    AGR53512.1    CH933808    EDW09248.1    ABLF02034413    AK341795    BAH72087.1    GFDF01000048    JAV14036.1    AJWK01028342    CH940648    EDW61851.1    GDHF01019722    JAI32592.1    JRES01000655    KNC29584.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000037510    UP000007151    + More
UP000008237    UP000002358    UP000078541    UP000053097    UP000279307    UP000075809    UP000078492    UP000007755    UP000078540    UP000005205    UP000002320    UP000095301    UP000075885    UP000075840    UP000007062    UP000075881    UP000075900    UP000076407    UP000075886    UP000075920    UP000075901    UP000076408    UP000075883    UP000069940    UP000249989    UP000008820    UP000030765    UP000000673    UP000075880    UP000075884    UP000192223    UP000069272    UP000019118    UP000030742    UP000075882    UP000009046    UP000000311    UP000235965    UP000078542    UP000095300    UP000078200    UP000092444    UP000092460    UP000092443    UP000092445    UP000091820    UP000053825    UP000005203    UP000001555    UP000027135    UP000053105    UP000076502    UP000007266    UP000015103    UP000245037    UP000009192    UP000007819    UP000092461    UP000008792    UP000037069   

PRIDE

H9J3S5   

Pfam

PF09430   DUF2012        + More
PF16033   DUF4789
PF00397   WW
PF05773   RWD
PF01485   IBR

Interpro

IPR019008   DUF2012        + More
IPR039163   EMC7       
IPR013784   Carb-bd-like_fold       
IPR031993   DUF4789       
IPR011524   SARAH_dom       
IPR030030   Sav       
IPR001202   WW_dom       
IPR036020   WW_dom_sf       
IPR006575   RWD-domain       
IPR002867   IBR_dom       
IPR031127   E3_UB_ligase_RBR       
IPR017907   Znf_RING_CS       
IPR016135   UBQ-conjugating_enzyme/RWD       
IPR013083   Znf_RING/FYVE/PHD       

SUPFAM

SSF49452   SSF49452        + More
SSF51045   SSF51045       
SSF54495   SSF54495       

Gene 3D

3.10.110.10     3.30.40.10    

CDD

cd00201  WW

ProteinModelPortal

H9J3S5   A0A1E1W412   A0A2W1BLY2   A0A2A4K544   A0A194QYQ1   A0A194PNH5   + More
A0A2H1VV04   A0A0L7LRK5   A0A212F3U7   A2IA77   E2BU45   K7IVQ9   A0A195F989   A0A026WRN8   A0A151WFG6   E9IET0   A0A195EAE0   F4WYW6   A0A151HZV2   A0A158NC77   B0WGQ0   T1PA78   V5GTB2   A0A182PSR5   A0A182IDH5   Q7Q7Q1   A0A1Q3FGS4   A0A182JVX4   A0A182REA0   A0A182XDR6   A0A182R081   A0A182VPS0   A0A182SJP1   A0A182YES2   A0A182MBI8   A0A182G2P4   A0A023EL35   A0A023EN45   Q16NH4   A0A2M4BYE6   A0A084W7X0   W5JWT6   A0A2M3Z7B3   A0A182J0X8   A0A182NE00   A0A1W4WJB0   A0A2M4AKI0   A0A2M4AL08   A0A0A1X7S3   A0A182FP49   J3JWP2   A0A182LNQ4   E0VD72   E2A1Q6   A0A2J7QFD5   A0A151IK28   A0A1I8QAU9   A0A1A9UI49   A0A1A9YUE3   A0A1Y1KJF1   A0A1L8EBV1   A0A1B0BGB0   A0A1A9XG18   A0A1A9Z5L5   A0A240SWE6   A0A1B6EB66   A0A0L7R4N6   A0A293LNH9   A0A310SC11   G3MPE5   A0A023FL78   A0A023GMQ3   A0A088ANN1   B7Q0N4   A0A067REF8   A0A0M8ZWR2   A0A154NYB5   A0A0K8RMC8   A0A131Y755   A0A336LID4   L7M4Q2   A0A131ZBN0   D6WR13   A0A1B6GED0   T1IA13   A0A1Z5L2I3   A0A1B6MTD0   T1JN94   A0A0P4W4E5   A0A1L8E755   A0A2P8ZJB1   A0A2H8THK5   S5MJX0   B4KQC0   C4WW17   A0A1L8E5T4   A0A1B0CU26   B4LL44   A0A0K8V0Y4   A0A0L0CDN3  

KEGG

101744887    no KO assigned | (RefSeq) ER membrane protein complex subunit 7

GO

GO:0030246   GO:0016021   GO:0072546   GO:0007165   GO:0005840   GO:0046872   GO:0004842   GO:0005576   GO:0004866   GO:0005615   GO:0005524   GO:0006139   GO:0019205   GO:0043564   GO:0006418   GO:0003824  

PANTHER

PTHR13605   PTHR10316:SF70   PTHR11685  

SignalP

Position:   1 - 20,         Likelihood:  0.951448

 

 

Length:

222

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

24.27715

Exp number, first 60 AAs:

3.20666

Total prob of N-in:

0.71632

inside

1  -  146

TMhelix

147  -  166

outside

167  -  222

 

 

Pi

21.074522

Theta

17.873599

Tajima's D

0.559023

CLR

0.536944

CSRT

0.542222888855557

Interpretation

Uncertain