Gene

KWMTBOMO11710  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004175

Annotation

eukaryotic_translation_initiation_factor_3_subunit_J_[Bombyx_mori]

Location

Bomo_Chr19(+):12325329-12334668      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit J      

Alternative Name

Eukaryotic translation initiation factor 3 subunit 1
eIF-3-alpha
eIF3 p35

Location in the cell

Nuclear   Reliability : 2.801

CDS

ATGGACGTGTCATGGGACGCAGATAACTTCGAGCCCAAACTCCCGACCACGTTGGCAGCTTCCAACAAATGGGAAGGGGAAGACGAGGATGATAACGTAAAGGAAAGCTGGGAGGATGAGGAGGAGGAAAAGAAAGACGAAGAAAAGACTGAGGCAGCGCCACCTCCACAACCGAAACCTAAAAAGAAAATACACGATAAAATAGCCGAAAGAGAGCGACAAGAACGTGAGAAGGCTGAACGTCTCGTGACAGAGAAGACTGCAGAAGAAATGACTCCAGAGCAGAAGTTGGCTGAGAAACTTCGCCAGCAGAAGCTACAGGAAGAATCAGATTTGCGACTAGCCATGGAAACCTTTGGTGTAACAGAAGGTAACATTGGTAAACTTGACAATTTCCACCCAACTACAAAAGAAGAGTACACAGAGTTTGCTGATCTCCTTACAAAGAAGATCACTTTCTATAAAGCCAAGGATGAATTTCCAGGATTCATTGATGACCTAGTCAAGAATATTTTAGTCCAGATGTCATCAGCGGATATCCGACGAATAAAATTGACTGTCGATAATCTATATATTGAAAAACAGAAGGCAGAAAAGAATGATAAAACTAAGAAGGCCACAAAGGGCAAGGGCAAGGCCAAGTTAAAACTTGAAGGGGACAATGCTCATCTCAATCAATACGAATCATATGGGAATTTCGATGACGACTACGATGATTTCATTTAA

Protein

MDVSWDADNFEPKLPTTLAASNKWEGEDEDDNVKESWEDEEEEKKDEEKTEAAPPPQPKPKKKIHDKIAERERQEREKAERLVTEKTAEEMTPEQKLAEKLRQQKLQEESDLRLAMETFGVTEGNIGKLDNFHPTTKEEYTEFADLLTKKITFYKAKDEFPGFIDDLVKNILVQMSSADIRRIKLTVDNLYIEKQKAEKNDKTKKATKGKGKAKLKLEGDNAHLNQYESYGNFDDDYDDFI

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: eif3a, eif3b, eif3c, eif3d, eif3e, eif3f, eif3g, eif3h, eif3i, eif3j, eif3k, eif3l and eif3m.

Similarity

Belongs to the eIF-3 subunit J family.

Keywords

Coiled coil   Complete proteome   Cytoplasm   Initiation factor   Protein biosynthesis   Reference proteome  

Feature

chain  Eukaryotic translation initiation factor 3 subunit J

Uniprot

Q0ZB73   I4DR42   A0A194QYS3   A0A0N1I3T8   A0A194QCK2   A0A3S2NJI1   + More
A0A1E1W2U0   S4PWF1   A0A2A4JHC5   A0A212F025   T1DIJ3   A0A088A861   A0A310SQW5   A0A0M9A2N2   A0A2A3E218   V9IHH9   A0A2P8YR41   A0A1Q3F7Q5   A0A1Q3F7I2   Q8I1G8   D6WTE4   B4NX24   A0A182H7Q0   A0A3L8D3Q5   A0A0B4LF26   Q7K550   E0VQW2   B3MF39   A0A0J9TXQ8   B4QHU5   B4IMQ8   Q8I1E5   B4GIF2   U5EZC7   Q16MK2   A0A0L7RHC7   B0WCZ5   A0A2J7PCV3   B4LN42   B4MP81   A0A1W4ULL5   A0A0M4EES5   A0A3B0J4T6   A0A3B0JPE2   A0A3B4E527   E2A2T5   A0A026VV76   A2I3V2   A0A195B017   A0A158NKD4   A0A154P5S6   F4W8N4   A0A195EIP5   A0A0P5T430   A0A0P5DST5   A0A0P5VZM0   A0A067RFE3   A0A0P6DE01   A0A0T6AV50   A0A3B4CIZ9   A0A0K8TQW0   J9JNK4   A0A2D0SE88   A0A1L8GSF6   Q6INR1   A0A0P6E4L9   A0A0B7BL25   A0A0P4XHH1   A0A1W4WM53  

Pubmed

22651552    26354079    23622113    22118469    24330624    29403074    + More
12537575    17994087    18362917    19820115    26483478    30249741    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    17392269    20566863    22936249    15632085    17510324    20798317    24508170    21347285    21719571    24845553    26369729    27762356   

EMBL

DQ645463    AK404931    BAM20382.1    KQ460949    KPJ10439.1    KQ458914    + More
KPJ04564.1    KQ459185    KPJ03197.1    RSAL01000070    RVE49168.1    GDQN01009833    JAT81221.1    GAIX01006898    JAA85662.1    NWSH01001571    PCG70833.1    AGBW02011173    OWR47106.1    GALA01000901    JAA93951.1    KQ761155    OAD58155.1    KQ435756    KOX75967.1    KZ288473    PBC25306.1    JR045376    AEY59966.1    PYGN01000419    PSN46705.1    GFDL01011527    JAV23518.1    GFDL01011533    JAV23512.1    AY190939    CH954177    KQ971352    EFA06707.1    CM000157    JXUM01000444    QOIP01000013    RLU15147.1    AE013599    AHN56058.1    AY051457    DS235442    EEB15768.1    CH902619    CM002911    KMY92630.1    CM000362    CH481150    AY190942    CM000071    CH479183    GANO01001032    JAB58839.1    CH477859    KQ414592    KOC70208.1    DS231892    NEVH01026403    PNF14156.1    CH940648    AY190959    CH963849    CP012524    ALC41726.1    OUUW01000001    SPP74532.1    SPP74531.1    GL436214    EFN72242.1    KK107804    EZA47575.1    EF070455    ABM55521.1    KQ976692    KYM77801.1    ADTU01018784    KQ434809    KZC06548.1    GL887908    EGI69525.1    KQ978881    KYN27734.1    GDIP01135760    JAL67954.1    GDIP01151157    JAJ72245.1    GDIP01107456    JAL96258.1    KK852722    KDR17725.1    GDIQ01082065    JAN12672.1    LJIG01022772    KRT78795.1    GDAI01001308    JAI16295.1    ABLF02029688    ABLF02029698    CM004471    OCT86716.1    BC072212    GDIQ01067919    JAN26818.1    HACG01046732    CEK93597.1    GDIP01243011    JAI80390.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000283053    UP000218220    UP000007151    + More
UP000005203    UP000053105    UP000242457    UP000245037    UP000008711    UP000007266    UP000002282    UP000069940    UP000279307    UP000000803    UP000009046    UP000007801    UP000000304    UP000001292    UP000001819    UP000008744    UP000008820    UP000053825    UP000002320    UP000235965    UP000008792    UP000007798    UP000192221    UP000092553    UP000268350    UP000261440    UP000000311    UP000053097    UP000078540    UP000005205    UP000076502    UP000007755    UP000078492    UP000027135    UP000007819    UP000221080    UP000186698    UP000192223   

PRIDE

Q0ZB73    Q7K550    B4LN42    Q6INR1   

Pfam

PF08597   eIF3_subunit

Interpro

IPR023194   eIF3-like_dom_sf        + More
IPR013906   eIF3j       

Gene 3D

1.10.246.60    

ProteinModelPortal

Q0ZB73   I4DR42   A0A194QYS3   A0A0N1I3T8   A0A194QCK2   A0A3S2NJI1   + More
A0A1E1W2U0   S4PWF1   A0A2A4JHC5   A0A212F025   T1DIJ3   A0A088A861   A0A310SQW5   A0A0M9A2N2   A0A2A3E218   V9IHH9   A0A2P8YR41   A0A1Q3F7Q5   A0A1Q3F7I2   Q8I1G8   D6WTE4   B4NX24   A0A182H7Q0   A0A3L8D3Q5   A0A0B4LF26   Q7K550   E0VQW2   B3MF39   A0A0J9TXQ8   B4QHU5   B4IMQ8   Q8I1E5   B4GIF2   U5EZC7   Q16MK2   A0A0L7RHC7   B0WCZ5   A0A2J7PCV3   B4LN42   B4MP81   A0A1W4ULL5   A0A0M4EES5   A0A3B0J4T6   A0A3B0JPE2   A0A3B4E527   E2A2T5   A0A026VV76   A2I3V2   A0A195B017   A0A158NKD4   A0A154P5S6   F4W8N4   A0A195EIP5   A0A0P5T430   A0A0P5DST5   A0A0P5VZM0   A0A067RFE3   A0A0P6DE01   A0A0T6AV50   A0A3B4CIZ9   A0A0K8TQW0   J9JNK4   A0A2D0SE88   A0A1L8GSF6   Q6INR1   A0A0P6E4L9   A0A0B7BL25   A0A0P4XHH1   A0A1W4WM53  

PDB

3BPJ     E-value=0.0116832,     Score=88

KEGG

733089    K03245 translation initiation factor 3 subunit J | (RefSeq) eIF3j; eukaryotic translation initiation

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0033290   GO:0001732   GO:0005852   GO:0003743   GO:0016282   GO:0006446   GO:0006413   GO:0016021   GO:0005737   GO:0042626   GO:0006434   GO:0043564   GO:0006418   GO:0003824  

PANTHER

PTHR21681  

Subcellular location

Cytoplasm  

Length:

241

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.05247

outside

1  -  241

 

 

Pi

26.909199

Theta

27.700356

Tajima's D

-0.703072

CLR

0.354607

CSRT

0.1980400979951

Interpretation

Uncertain