Gene

KWMTBOMO11695

Pre Gene Modal

BGIBMGA003968

Annotation

PREDICTED:_putative_phosphatidate_phosphatase_[Papilio_xuthus]

Location

Bomo_Chr19(-):11463726-11476636      View in EpiBrowser

Full name

Putative phosphatidate phosphatase      

Alternative Name

Germ cell guidance factor
Phosphatidic acid phosphatase type 2
Protein wunen

Location in the cell

PlasmaMembrane   Reliability : 4.881

CDS

ATGGCTGTTGATAGATTAATATGGAAAATTATTGTGGATTTCGTTGTGCTCGCGTGCGTTTCATTCCCCCTGCTTGCTCTGCTGCTGTGGGCGGAGCCCTATCACCGCGGCTACTTTGAAGATGACCTTTCTCTGCGACTGCCCTTTAAACAGCAGTCCATATCGGAAGGGCTCTTGGCTGGCGTCGGCTTCGCTTTCATTATTTTCACGGTTCTAATCACTGAGATAGTGCGTGACAGGCAAGGTAAGGGCATCGGCGGAAAGTTTCTGTCGGGGTCGCTGATACCGGGCTGGCTGTGGGAGACGTACTCGACCGTGGGAATCTTCACGTTTGGGGCCGCCTGTCAACAGCTCACAGCCAACCTCGCGAAGTACGTGATCGGGAGACTGCGCCCACATTTCTTCGATGTCTGCAGGCCGATCCCGGACGCCGGATCCTCGCAGAACGCCCTCGGCTACATCCAGGAGTACCGATGTAGCGGTGGCGATGAGGCTCTCTTGAAGGACATGCGCCTCTCGTTTCCGAGTGCACACGCAAGCTTCTCTATGTACTGTGCCATATTCTTTATCTTCTACATCCAAGTGAAAGGCAAGTGGCGGGGCTCGAAGCTCCTCCGTCACGGAGTCCAGTATGCCGTTGTGATAGCGGCCTGGTACGTGGGGCTCTCGAGGGTGGTGGAACATATGCACCACTGGAGCGACGTGGCGGCTGGTTTCGCCATAGGCGCCACATACGCTATGCTTATTTTCATCTTCGTTCTGAAGCCGAAGAAGTACGGCGCACCAGAGACGTGGCAGCAGCCGGTGCCCAGGAATACGCTTCCCAGGCCGGTACTGGCGCGGTGA

Protein

MAVDRLIWKIIVDFVVLACVSFPLLALLLWAEPYHRGYFEDDLSLRLPFKQQSISEGLLAGVGFAFIIFTVLITEIVRDRQGKGIGGKFLSGSLIPGWLWETYSTVGIFTFGAACQQLTANLAKYVIGRLRPHFFDVCRPIPDAGSSQNALGYIQEYRCSGGDEALLKDMRLSFPSAHASFSMYCAIFFIFYIQVKGKWRGSKLLRHGVQYAVVIAAWYVGLSRVVEHMHHWSDVAAGFAIGATYAMLIFIFVLKPKKYGAPETWQQPVPRNTLPRPVLAR

Description

Responsible for guiding the germ cells early in the process of migration from the lumen of the developing gut towards the overlying mesoderm, where the germ cells enter the gonads. May be involved in lipid metabolism.

Catalytic Activity

a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate

Subunit

Homodimer. This complex seems not to be involved in substrate recognition, it may confer only structural or functional stability.

Similarity

Belongs to the PA-phosphatase related phosphoesterase family.

Keywords

Alternative splicing   Complete proteome   Developmental protein   Glycoprotein   Hydrolase   Membrane   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  Putative phosphatidate phosphatase
splice variant  In isoform Short.

Uniprot

H9J381   A0A194R3N3   A0A194Q9B3   A0A2H1WI45   A0A194QE37   A0A2H1W730   + More
A0A212FNI3   S4PY41   A0A212FNH6   A0A2A4JNX9   A0A3S2LX18   A0A1Y1MVF2   B4J876   B0VZ03   A0A1Q3FHC6   A0A1L8DY84   B4KQ09   B4MDV3   A0A1L8E725   A0A0Q9W0A7   Q172P3   A0A1L8DYT5   A0A0Q9XJA5   A0A0K8TTU9   A0A2J7R5L3   A0A1L8EIS0   A0A1L8EIW2   A0A1L8EIM8   A0A1L8E5Z5   W8BIL3   A0A2M4CJY6   A0A1L8E5W3   A0A2M4CIP2   A0A1J1ISA8   A0A0A1XTI2   A0A023EPH9   A0A2M4ARF8   A0A3B0J214   B4MPQ4   T1HKB2   A0A182HE45   A0A182QVZ1   D3TMP7   A0A1L8EJ03   A0A3B0IY91   A0A1L8EJ51   A0A1L8EIR9   A0A067QTP7   A0A1B6KNY2   A0A034VNU9   A0A0K8VEM0   B3MFK0   E0VQY9   A0A182FLB6   A0A034VMY9   A0A224XH03   A0A336MP79   B4GHS9   A0A0J9R9Z7   A0A0P9BY25   W8CAT4   B4QH88   A0A182JFU0   A0A0A9Y9L2   A0A0M4EKC2   A0A0K8S5D9   A0A0R1DMD4   U5EWL0   Q28ZG6   A0A0A9Y520   A0A084WDR5   N6WBT2   A0A2M3Z9K7   A0A1B6GLP9   B4HSS1   A0A0V0G785   C7LA91   B4P418   A0A0B4K7K7   Q9V576-2   A0A0K8S456   A0A146KZH3   Q9V576   B3N7H0   A0A0Q5WNR8   A0A0P5J5A0   A0A1W4VCA5   A0A0P5KF95   A0A0P5KUL5   A0A026WG83   A0A1B0AHS6   A0A1W4VBV9   E2BZ71   A0A0G3YL55   A0A0P5CUQ6   A0A0N8A367   E2ASD3   A0A182WM77  

EC Number

3.1.3.4

Pubmed

19121390    26354079    22118469    23622113    28004739    17994087    + More
17510324    26369729    24495485    25830018    24945155    26483478    20353571    24845553    25348373    18057021    20566863    22936249    25401762    17550304    15632085    26823975    24438588    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    8985246    10731138    12537569    12856002    14725715    24508170    30249741    20798317    25702953   

EMBL

BABH01021749    KQ460949    KPJ10451.1    KQ459252    KPJ02102.1    ODYU01008797    + More
SOQ52707.1    KQ459185    KPJ03210.1    ODYU01006741    SOQ48868.1    AGBW02005277    OWR55304.1    GAIX01003948    JAA88612.1    OWR55302.1    NWSH01000947    PCG73418.1    RSAL01000136    RVE46217.1    GEZM01023368    JAV88425.1    CH916367    EDW01213.1    DS231813    EDS25757.1    GFDL01008088    JAV26957.1    GFDF01002710    JAV11374.1    CH933808    EDW08111.2    CH940662    EDW58718.1    GFDG01004345    JAV14454.1    KRF78429.1    CH477433    EAT41005.1    GFDF01002649    JAV11435.1    KRG03912.1    GDAI01000228    JAI17375.1    NEVH01006994    PNF36111.1    GFDG01000241    JAV18558.1    GFDG01000240    JAV18559.1    GFDG01000242    JAV18557.1    GFDG01004671    JAV14128.1    GAMC01005437    GAMC01005435    JAC01121.1    GGFL01001030    MBW65208.1    GFDG01004672    JAV14127.1    GGFL01001029    MBW65207.1    CVRI01000059    CRL03032.1    GBXI01000199    JAD14093.1    JXUM01023906    JXUM01023907    JXUM01023908    JXUM01023909    GAPW01002201    KQ560674    JAC11397.1    KXJ81330.1    GGFK01010064    MBW43385.1    OUUW01000001    SPP72963.1    CH963849    EDW74093.1    ACPB03006494    JXUM01035044    JXUM01035045    JXUM01035046    JXUM01035047    JXUM01035048    JXUM01035049    KQ561046    KXJ79901.1    AXCN02000966    EZ422699    ADD18975.1    GFDG01000175    JAV18624.1    SPP72964.1    GFDG01000176    JAV18623.1    GFDG01000244    JAV18555.1    KK853284    KDR08980.1    GEBQ01026846    JAT13131.1    GAKP01015462    JAC43490.1    GDHF01028491    GDHF01015052    JAI23823.1    JAI37262.1    CH902619    EDV36685.1    KPU76358.1    DS235442    EEB15795.1    GAKP01015460    JAC43492.1    GFTR01004661    JAW11765.1    UFQT01001933    SSX32172.1    CH479183    EDW36049.1    CM002911    KMY92509.1    KPU76359.1    GAMC01005436    JAC01120.1    CM000362    EDX06342.1    KMY92508.1    GBHO01017402    GBHO01017399    JAG26202.1    JAG26205.1    CP012524    ALC41817.1    GBRD01017872    JAG47955.1    CM000157    KRJ98495.1    GANO01001369    JAB58502.1    CM000071    EAL25647.2    GBHO01017401    GDHC01017279    GDHC01000397    JAG26203.1    JAQ01350.1    JAQ18232.1    ATLV01023054    KE525340    KFB48359.1    ENO01639.1    GGFM01004431    MBW25182.1    GECZ01006414    JAS63355.1    CH480816    EDW47098.1    GECL01002156    JAP03968.1    BT099641    ACU68950.1    EDW89501.1    AE013599    AFH07978.1    U73822    AF145595    BT001729    AY046533    GBRD01017873    JAG47954.1    GDHC01018237    JAQ00392.1    CH954177    EDV59375.1    KQS70778.1    GDIQ01210794    JAK40931.1    GDIQ01186573    JAK65152.1    GDIQ01186572    JAK65153.1    KK107231    QOIP01000009    EZA55072.1    RLU18933.1    GL451577    EFN78977.1    KM507105    AKM28429.1    GDIP01170944    JAJ52458.1    GDIP01187001    JAJ36401.1    GL442284    EFN63667.1   

Proteomes

UP000005204    UP000053240    UP000053268    UP000007151    UP000218220    UP000283053    + More
UP000001070    UP000002320    UP000009192    UP000008792    UP000008820    UP000235965    UP000183832    UP000069940    UP000249989    UP000268350    UP000007798    UP000015103    UP000075886    UP000027135    UP000007801    UP000009046    UP000069272    UP000008744    UP000000304    UP000075880    UP000092553    UP000002282    UP000001819    UP000030765    UP000001292    UP000000803    UP000008711    UP000192221    UP000053097    UP000279307    UP000092445    UP000008237    UP000000311    UP000075920   

PRIDE

H9J381    C7LA91    Q9V576   

Pfam

PF01569   PAP2

Interpro

IPR036938   P_Acid_Pase_2/haloperoxi_sf        + More
IPR000326   P_Acid_Pase_2/haloperoxidase       

SUPFAM

SSF48317   SSF48317       

ProteinModelPortal

H9J381   A0A194R3N3   A0A194Q9B3   A0A2H1WI45   A0A194QE37   A0A2H1W730   + More
A0A212FNI3   S4PY41   A0A212FNH6   A0A2A4JNX9   A0A3S2LX18   A0A1Y1MVF2   B4J876   B0VZ03   A0A1Q3FHC6   A0A1L8DY84   B4KQ09   B4MDV3   A0A1L8E725   A0A0Q9W0A7   Q172P3   A0A1L8DYT5   A0A0Q9XJA5   A0A0K8TTU9   A0A2J7R5L3   A0A1L8EIS0   A0A1L8EIW2   A0A1L8EIM8   A0A1L8E5Z5   W8BIL3   A0A2M4CJY6   A0A1L8E5W3   A0A2M4CIP2   A0A1J1ISA8   A0A0A1XTI2   A0A023EPH9   A0A2M4ARF8   A0A3B0J214   B4MPQ4   T1HKB2   A0A182HE45   A0A182QVZ1   D3TMP7   A0A1L8EJ03   A0A3B0IY91   A0A1L8EJ51   A0A1L8EIR9   A0A067QTP7   A0A1B6KNY2   A0A034VNU9   A0A0K8VEM0   B3MFK0   E0VQY9   A0A182FLB6   A0A034VMY9   A0A224XH03   A0A336MP79   B4GHS9   A0A0J9R9Z7   A0A0P9BY25   W8CAT4   B4QH88   A0A182JFU0   A0A0A9Y9L2   A0A0M4EKC2   A0A0K8S5D9   A0A0R1DMD4   U5EWL0   Q28ZG6   A0A0A9Y520   A0A084WDR5   N6WBT2   A0A2M3Z9K7   A0A1B6GLP9   B4HSS1   A0A0V0G785   C7LA91   B4P418   A0A0B4K7K7   Q9V576-2   A0A0K8S456   A0A146KZH3   Q9V576   B3N7H0   A0A0Q5WNR8   A0A0P5J5A0   A0A1W4VCA5   A0A0P5KF95   A0A0P5KUL5   A0A026WG83   A0A1B0AHS6   A0A1W4VBV9   E2BZ71   A0A0G3YL55   A0A0P5CUQ6   A0A0N8A367   E2ASD3   A0A182WM77  

KEGG

101745213    K01080 phosphatidate phosphatase [EC:3.1.3.4] | (RefSeq) putative phosphatidate phosphatase

PATHWAY

00561    Glycerolipid metabolism - Bombyx mori (domestic silkworm)
00564    Glycerophospholipid metabolism - Bombyx mori (domestic silkworm)
00565    Ether lipid metabolism - Bombyx mori (domestic silkworm)
00600    Sphingolipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0005918   GO:0045177   GO:0007424   GO:0016791   GO:0035233   GO:0019991   GO:0008195   GO:0008354   GO:0009880   GO:0016311   GO:0050829   GO:0045824   GO:0007280   GO:0035234   GO:0042803   GO:0016787  

Subcellular location

Membrane  

Length:

281

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

124.26041

Exp number, first 60 AAs:

28.06507

Total prob of N-in:

0.95978

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  53

TMhelix

54  -  76

inside

77  -  88

TMhelix

89  -  111

outside

112  -  173

TMhelix

174  -  193

inside

194  -  204

TMhelix

205  -  222

outside

223  -  231

TMhelix

232  -  254

inside

255  -  281

 

 

Pi

19.340456

Theta

18.14472

Tajima's D

-1.055387

CLR

0.803256

CSRT

0.128943552822359

Interpretation

Uncertain