SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO11691  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA003971
Annotation
PREDICTED:_uncharacterized_protein_LOC106137262_[Amyelois_transitella]
Full name
Hillarin      
Alternative Name
D-Hillarin
Location in the cell
Nuclear   Reliability : 3.186
 

Sequence

CDS
ATGTGCTTAAGGATTCCTTCCACCTCCTCACAATACCTGCAGACTGGATCAGCAGATCGAGATGAGCAAACCAAACTTGAAATGAAACACCGGCAAGAAGAAGACGATTTGTACAGGAAATTCTCGAAACATAGAGAAGAAGAAAATAGAAGAATACGTGAAGAAATACAGGACGAATGGGAGCGCGAATTAGAAAGGCTGACCAGCCGGTTCCAACAAGAAATGCAGGTGAAAAAGAGAAGACCAGACGCCGAGATCGGTGCTCTAACCCTACGGCATCAGCAGGAACGGGCAGACCTGGAGAAGAACATGACACTTCGTAGGGATAAGAAGAAAGAAAGTTTAACCAGGAAAATGTTGGAGCACGAAAGGGCGGCAACAGCAGCTCTAGTCGAGAAGCAAAGTCACGAAATGATGGAGCTGATCCAGGAACGTCGTTCGGAGTACATGGCGGCATCTTCACTGTACGTGGATGGGGAGGAAGCTCCTCCGTACCCAGCCCGAGCCCCGCCTCCCCAACCACCGCTAGTATCGAAGTTCCACATCTACACCGACCCGGCGGAGTTCTCCGAAGTCGATAAAATTGCTATTTCGGTAGCACAAGAAGACCAAAAAACCTTCACGGATTTAGTTCGGCAACTCGTCGGCAGATGTGCAAGTGACGTAGAGAAGGCGAGGACTATCTTCCGGTGGATTACTGTGAAGAATCTGAACAATATTCAATTTGACGACAACCTTCGAGGGGATTCTCCATTAGGGTTGCTGAGGGGAATCAAACATGGCACAGAGAGTTACCACGTCTTATTCAAGAGATTGTGCAGCTACGCAGGTCTTCATTGCGTGGTCATAAAGGGGTACAGCAAGTCGGCCGGCTACCAACCAGGAGTGCGCTTCGAAGACAACAGATTCCGTAACTCTTGGAACGCCGTGTACGTGGCGGGAGCGTGGCGCTTCGTGCAGTGTAACTGGGGCGCCAGACATTTGGTCAACGCAAAGGACGCTCCTAAGCCCGGGAACAGAGGGAAAAGTGATAGTTTGAGATACGAATATGACGACCATTACTTCCTGACGGACCCTAGGGAGTTCATCTACGAGTTTTTCCCTCTTCAGCCGGACTGGCAGTTGCTGAAGACGCCCATCACTCTACACGACTTCGAGGAGTTGCCGTTCGTGCGATCCCTCTTCTTCAGATACGGACTATACTTCAGCGATCCTAACACCAAGGCGGTCATGTACACTGACTCGACTGGTGCGGCGACTATGCGCATAGCCATGCCTGCACACATGCAGAGCTCGCTGATCTTCCACTACAACCTCAAGTTCTATGATACGGAGGGAGATGGTTTTGATGGAGTCAGCCTCAAGAGATTTGTTATGCAGTCAGTTGTGGGCAATGTGGTGTCATTCCGAGTGCACGCTCCGTGCAGCGGTGCCTTCCTGCTCGACATCTTCGCGAACGCTGTCACTCCAAGGGAATACCTCACCGGCGAACCAATGAAGTTCAAGAGTGTCTGCAAATTTAAGATTTGTTGTGCGGAACTACAGACTGTGATGGTACCGCTGCCGGACTGCGCGAGTGGAGAGTGGGGTCCGACTAAAGCCACAAGGCTCTTTGGACTCGTACCTATAACTCACCAGGAAGCATTAGTGTTCGCGGGTCGGGAACTAGAAATTCAATTCCGAATGTCGCGCCCACTGGCGGACTTCATGGCAACACTGCACAAAAATGGCGTCGACGAAAAACGTTTGTCGAAATACGTGCAACAAAACGTTTCTGATGACATCGTATCGTTTTATATAACTTTTCCGGAGGAGGGTCAATATGGTCTCGACATTTACACCCGTGAGCGTGGAGGACCTACGGCCATCCACCAGAACGGCTCCACCGAGAAGGAGAAGCACCTCCTAACTCACTGCTGCAAGTACCTCATCAACAGCAGTAAAAGGAATTGA
Protein
MCLRIPSTSSQYLQTGSADRDEQTKLEMKHRQEEDDLYRKFSKHREEENRRIREEIQDEWERELERLTSRFQQEMQVKKRRPDAEIGALTLRHQQERADLEKNMTLRRDKKKESLTRKMLEHERAATAALVEKQSHEMMELIQERRSEYMAASSLYVDGEEAPPYPARAPPPQPPLVSKFHIYTDPAEFSEVDKIAISVAQEDQKTFTDLVRQLVGRCASDVEKARTIFRWITVKNLNNIQFDDNLRGDSPLGLLRGIKHGTESYHVLFKRLCSYAGLHCVVIKGYSKSAGYQPGVRFEDNRFRNSWNAVYVAGAWRFVQCNWGARHLVNAKDAPKPGNRGKSDSLRYEYDDHYFLTDPREFIYEFFPLQPDWQLLKTPITLHDFEELPFVRSLFFRYGLYFSDPNTKAVMYTDSTGAATMRIAMPAHMQSSLIFHYNLKFYDTEGDGFDGVSLKRFVMQSVVGNVVSFRVHAPCSGAFLLDIFANAVTPREYLTGEPMKFKSVCKFKICCAELQTVMVPLPDCASGEWGPTKATRLFGLVPITHQEALVFAGRELEIQFRMSRPLADFMATLHKNGVDEKRLSKYVQQNVSDDIVSFYITFPEEGQYGLDIYTRERGGPTAIHQNGSTEKEKHLLTHCCKYLINSSKRN

Summary

Description
May act as a modulator of septin function during cytokinesis in the developing nervous system.
Subunit
Interacts with pnut.
Similarity
Belongs to the transglutaminase-like superfamily.
Keywords
Coiled coil   Complete proteome   Cytoplasm   LIM domain   Metal-binding   Reference proteome   Zinc  
Feature
chain  Hillarin
EMBL
BABH01021742    BABH01021743    ODYU01000021    SOQ34084.1    AGBW02005277    OWR55308.1    + More
KQ459185    KPJ03213.1    KQ460949    KPJ10455.1    NWSH01001673    PCG70452.1    PCG70453.1    KK853284    KDR08978.1    NEVH01006994    PNF36106.1    KQ971354    EFA06195.2    PYGN01000284    PSN49335.1    GEZM01007728    GEZM01007727    GEZM01007726    GEZM01007725    GEZM01007724    GEZM01007723    GEZM01007722    JAV94978.1    GECZ01017813    GECZ01000628    JAS51956.1    JAS69141.1    GEBQ01031439    JAT08538.1    APGK01045628    KB741037    KB632319    ENN74667.1    ERL92289.1    GEDC01024898    GEDC01015531    GEDC01006041    JAS12400.1    JAS21767.1    JAS31257.1    GGMS01000209    MBY69412.1    GL450630    EFN80714.1    GL888070    EGI68211.1    KQ982662    KYQ52652.1    KQ414755    KOC61773.1    QOIP01000011    RLU16721.1    KZ288337    PBC27848.1    KQ980905    KYN11518.1    KQ435727    KOX78045.1    GL435158    EFN73942.1    KQ976398    KYM92697.1    GBBI01002546    JAC16166.1    KQ977259    KYN04609.1    ACPB03011534    ACPB03011535    ACPB03011536    ACPB03011537    GFXV01000543    MBW12348.1    ADTU01001749    ADTU01001750    NNAY01002442    OXU21265.1    AJWK01003822    AJWK01001848    AJWK01001849    AJWK01001850    GFDF01003109    JAV10975.1    KQ981979    KYN31306.1    GAKP01008812    JAC50140.1    GDHF01024935    GDHF01021434    GDHF01020517    GDHF01010661    GDHF01005767    JAI27379.1    JAI30880.1    JAI31797.1    JAI41653.1    JAI46547.1    GAMC01014050    GAMC01014048    GAMC01014047    JAB92508.1    GBXI01017206    GBXI01004146    JAC97085.1    JAD10146.1    PBC27849.1    JXJN01005201    JXJN01005202    AAAB01008948    EAA10341.3    CM000071    KRT02387.1    CH933808    EDW08240.1    JRES01001669    KNC21031.1    KRG04001.1    KRG04002.1    CH916367    EDW02423.1    APCN01004686    CH940662    EDW58874.1    KRF78568.1    KRF78569.1    CP012524    ALC41426.1    OUUW01000001    SPP73837.1    UFQT01000031    SSX18226.1    CH963849    EDW74252.1    EAL25574.1    KRT02386.1    CM002911    KMY95294.1    AE013599    AY052077    AAK93501.1    CH479183    EDW35774.1    CM000158    EDW91376.1    CH480816    EDW48722.1    CH954179    EDV55329.1    KQS62225.1    CCAG010018638    KK107403    EZA51317.1    GGMS01009934    MBY79137.1    CVRI01000035    CRK92892.1    CH902619    EDV36008.1    KPU75921.1    DS231813    EDS25756.1    GDIQ01078592    GDIQ01078591    JAN16145.1    GL732545    EFX80924.1    GDIP01164273    JAJ59129.1    GDIQ01147073    GDIQ01147072    JAL04653.1    GDIP01134536    JAL69178.1    GDIP01150074    GDIP01148788    JAJ73328.1    CH477433    EAT41006.1    GAPW01000232    JAC13366.1    ATLV01023054    ATLV01023055    ATLV01023056    KE525340    KFB48362.1    SPP73838.1    AXCN02000986    AXCM01002330    AXCM01002331    GDIP01044046    GDIP01043992    JAM59723.1    GDIP01027399    JAM76316.1   
Pfam
PF00412   LIM        + More
PF03439   Spt5-NGN
PF00467   KOW
PF11942   Spt5_N
Interpro
IPR038765   Papain-like_cys_pep_sf        + More
IPR002931   Transglutaminase-like       
IPR001781   Znf_LIM       
IPR005824   KOW       
IPR039385   NGN_Euk       
IPR006645   NGN_dom       
IPR041976   KOW_Spt5_3       
IPR008991   Translation_prot_SH3-like_sf       
IPR039659   SPT5       
IPR036735   NGN_dom_sf       
IPR024945   Spt5_C_dom       
IPR022581   Spt5_N       
IPR041975   KOW_Spt5_2       
IPR041978   KOW_Spt5_5       
IPR041973   KOW_Spt5_1       
IPR005100   NGN-domain       
IPR041977   KOW_Spt5_4       
IPR014722   Rib_L2_dom2       
SUPFAM
SSF54001   SSF54001        + More
SSF50104   SSF50104       
Gene 3D

Ontologies

Topology

Subcellular location
Cytoplasm   During mitosis, detected at the cell cortex in metaphase but is concentrated at the cleavage furrow at telophase. Colocalizes with pnut at the cell cortex.   With evidence from 3 publications.
Cell cortex   During mitosis, detected at the cell cortex in metaphase but is concentrated at the cleavage furrow at telophase. Colocalizes with pnut at the cell cortex.   With evidence from 3 publications.
Cleavage furrow   During mitosis, detected at the cell cortex in metaphase but is concentrated at the cleavage furrow at telophase. Colocalizes with pnut at the cell cortex.   With evidence from 3 publications.
Length:
650
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.01033
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00042
outside
1  -  650
 
 

Population Genetic Test Statistics

Pi
366.072553
Theta
210.06509
Tajima's D
3.310797
CLR
0.499867
CSRT
0.989900504974751
Interpretation
Uncertain
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