Gene

KWMTBOMO11673

Pre Gene Modal

BGIBMGA003981

Annotation

PREDICTED:_atrial_natriuretic_peptide_receptor_1_[Bombyx_mori]

Location

Bomo_Chr19(-):11088982-11096552      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

PlasmaMembrane   Reliability : 1.781

CDS

ATGATCATCTTTACGTGTGTATTGGTCTTGCCGATGTTGTCCGGTACGGTTTTAAACAAAACTGTATACAAAATAGGGGTCTTAATGGCCTCTCGGTTGGACTCGCCTTTTGACTTGGAAAGATGTGGACCGGCTGTGGACCTGGGACTTAAGAAAGTGAATGAAAAGTTTCTCTCGCATCACGGAATTGAGTTGGAGAAGGTTCAAGGAAGTTACCCATCGTGCTCGGGTGCCATAGCTCCGGGTTTGGCCGCCGACATGCACTTCAAGAACGACGTGATCGCTTTCATAGGACCCGCGTGCGCGTTCGCCTTGGAACCGGTTGCGAGGCTGGCCGCTTACTGGAATACTCCCATCATCACCGGAATGGGGGATCAGATAGTTCAGATTTAA

Protein

MIIFTCVLVLPMLSGTVLNKTVYKIGVLMASRLDSPFDLERCGPAVDLGLKKVNEKFLSHHGIELEKVQGSYPSCSGAIAPGLAADMHFKNDVIAFIGPACAFALEPVARLAAYWNTPIITGMGDQIVQI

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Feature

chain  Guanylate cyclase

Uniprot

A0A2A4JER9   A0A0L7LM81   H9J394   A0A2H1WLK9   A0A0N1IPJ9   A0A194QCN7   + More
A0A232EQ27   A0A212FAS7   D6WRM6   A0A194QY55   A0A1I8QAW1   A0A034VK64   A0A0M4E8Y6   A0A0Q9XIU0   A0A0Q9WDQ8   A0A182MJD1   A0A1I8MX63   A0A336KPL4   B4J8X4   A0A1B0G3T4   B4LQ69   B4KRH8   A0A3L8DR11   A0A1A9ZVI9   A0A1B0BZE8   A0A0L0C030   A0A182JJG6   A0A2S2PGL0   A0A151J3M2   A0A158NDH8   A0A195B5P1   A0A195F339   A0A0R1DS54   B4P9K3   A0A1W4V6D9   A0A154P996   A0A0P9BWM0   A0A2J7QWW5   B3MIB2   K7JAC0   B4NN48   A0A0Q5W083   A0A3B0JUU0   Q28X38   B4H4Z8   B3NK16   A0A310S5S1   A0A067RK75   A0A182KYH8   A0A0N0BDY8   Q9W2P1   A0A0J9RIQ1   B0W1T4   A0A2A3E503   A0A182QDM9   A0A2S2Q6P6   B4I7H3   Q8MLX0   B4QFJ8   A0A0J9U744   A0A2H8TER7   J9K9Z0   A0A182TFP5   A0A084VCP6   A0A087ZY46   A0A026WAY9   F4W994   A0A182GFN3   U4UHB1   A0A182P368   A0A151X8Y4   A0A182VTD2   E2APH5   A0A0L7RCA0   E9J755   A0A1S4GYZ1   A0A182F3A0   A0A151IAC0   W5JE51   Q7Q8C9   A0A226F360   A0A182VNR5   A0A1D2MPH3   R7TF11   V4ALG5   R7T4L4   A0A2P6KSU1   A0A087UZV2   A0A2T7PJ64   R7TBU9   T1KEH1  

EC Number

4.6.1.2

Pubmed

26227816    19121390    26354079    28648823    22118469    18362917    + More
19820115    25348373    17994087    25315136    30249741    26108605    21347285    17550304    20075255    15632085    24845553    20966253    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    22936249    24438588    24508170    21719571    26483478    23537049    20798317    21282665    12364791    20920257    23761445    27289101    23254933   

EMBL

NWSH01001857    PCG69902.1    JTDY01000654    KOB76321.1    BABH01021725    ODYU01009488    + More
SOQ53961.1    KQ460459    KPJ14653.1    KQ459185    KPJ03232.1    NNAY01002859    OXU20432.1    AGBW02009432    OWR50831.1    KQ971354    EFA07684.2    KQ460949    KPJ10473.1    GAKP01016440    GAKP01016438    JAC42512.1    CP012524    ALC41271.1    CH933808    KRG05220.1    CH940648    KRF79937.1    AXCM01008450    UFQS01000670    UFQT01000670    SSX05992.1    SSX26349.1    CH916367    EDW01323.1    CCAG010019265    EDW61354.2    EDW10404.2    QOIP01000005    RLU22831.1    JXJN01023105    JRES01001096    KNC25591.1    GGMR01015962    MBY28581.1    KQ980275    KYN17032.1    ADTU01001036    ADTU01001037    KQ976598    KYM79590.1    KQ981855    KYN34878.1    CM000158    KRJ99806.1    EDW91323.1    KQ434829    KZC07740.1    CH902619    KPU75902.1    NEVH01009413    PNF33087.1    EDV35957.1    AAZX01000434    AAZX01000435    AAZX01012324    AAZX01016843    CH964282    EDW85787.1    CH954179    KQS62239.1    OUUW01000001    SPP74838.1    CM000071    EAL26478.3    CH479210    EDW32834.1    EDV55382.1    KQ769179    OAD52914.1    KK852461    KDR23428.1    KQ435847    KOX71134.1    AE013599    AAF46649.2    CM002911    KMY95374.1    DS231823    EDS26635.1    KZ288369    PBC26770.1    AXCN02002197    GGMS01003659    MBY72862.1    CH480824    EDW56548.1    AAM68187.2    CM000362    EDX07990.1    KMY95375.1    GFXV01000769    MBW12574.1    ABLF02027323    ABLF02027327    ABLF02027333    ABLF02027334    ABLF02027335    ATLV01010838    KE524620    KFB35740.1    KK107293    EZA53272.1    GL888002    EGI69276.1    JXUM01060110    JXUM01060111    JXUM01060112    JXUM01060113    JXUM01060114    KQ562088    KXJ76720.1    KB632300    ERL91753.1    KQ982402    KYQ56837.1    GL441542    EFN64674.1    KQ414616    KOC68458.1    GL768421    EFZ11362.1    AAAB01008944    KQ978223    KYM96262.1    ADMH02001784    ETN61094.1    EAA10186.4    LNIX01000001    OXA63366.1    LJIJ01000725    ODM94989.1    AMQN01002821    AMQN01002822    KB310159    ELT92328.1    KB201304    ESO97952.1    AMQN01003544    KB312101    ELT87878.1    MWRG01005805    PRD29395.1    KK122519    KFM82891.1    PZQS01000003    PVD33471.1    AMQN01002981    AMQN01002982    KB310616    ELT91198.1    CAEY01002035   

Proteomes

UP000218220    UP000037510    UP000005204    UP000053240    UP000053268    UP000215335    + More
UP000007151    UP000007266    UP000095300    UP000092553    UP000009192    UP000008792    UP000075883    UP000095301    UP000001070    UP000092444    UP000279307    UP000092445    UP000092460    UP000037069    UP000075880    UP000078492    UP000005205    UP000078540    UP000078541    UP000002282    UP000192221    UP000076502    UP000007801    UP000235965    UP000002358    UP000007798    UP000008711    UP000268350    UP000001819    UP000008744    UP000027135    UP000075882    UP000053105    UP000000803    UP000002320    UP000242457    UP000075886    UP000001292    UP000000304    UP000007819    UP000075902    UP000030765    UP000005203    UP000053097    UP000007755    UP000069940    UP000249989    UP000030742    UP000075885    UP000075809    UP000075920    UP000000311    UP000053825    UP000069272    UP000078542    UP000000673    UP000007062    UP000198287    UP000075903    UP000094527    UP000014760    UP000030746    UP000054359    UP000245119    UP000015104   

PRIDE

H9J394    Q9W2P1    Q8MLX0   

Pfam

PF01094   ANF_receptor        + More
PF00211   Guanylate_cyc
PF07714   Pkinase_Tyr
PF07701   HNOBA
PF00149   Metallophos
PF12796   Ank_2
PF00069   Pkinase

Interpro

IPR028082   Peripla_BP_I        + More
IPR001828   ANF_lig-bd_rcpt       
IPR001170   ANPR/GUC       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR011009   Kinase-like_dom_sf       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR018297   A/G_cyclase_CS       
IPR011645   HNOB_dom_associated       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR041871   MPP_TMEM62       
IPR029052   Metallo-depent_PP-like       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       

SUPFAM

SSF53822   SSF53822        + More
SSF56112   SSF56112       
SSF55073   SSF55073       
SSF48403   SSF48403       

Gene 3D

3.30.70.1230     3.60.21.10     1.25.40.20    

CDD

cd07401  MPP_TMEM62_N
cd00204  ANK

ProteinModelPortal

A0A2A4JER9   A0A0L7LM81   H9J394   A0A2H1WLK9   A0A0N1IPJ9   A0A194QCN7   + More
A0A232EQ27   A0A212FAS7   D6WRM6   A0A194QY55   A0A1I8QAW1   A0A034VK64   A0A0M4E8Y6   A0A0Q9XIU0   A0A0Q9WDQ8   A0A182MJD1   A0A1I8MX63   A0A336KPL4   B4J8X4   A0A1B0G3T4   B4LQ69   B4KRH8   A0A3L8DR11   A0A1A9ZVI9   A0A1B0BZE8   A0A0L0C030   A0A182JJG6   A0A2S2PGL0   A0A151J3M2   A0A158NDH8   A0A195B5P1   A0A195F339   A0A0R1DS54   B4P9K3   A0A1W4V6D9   A0A154P996   A0A0P9BWM0   A0A2J7QWW5   B3MIB2   K7JAC0   B4NN48   A0A0Q5W083   A0A3B0JUU0   Q28X38   B4H4Z8   B3NK16   A0A310S5S1   A0A067RK75   A0A182KYH8   A0A0N0BDY8   Q9W2P1   A0A0J9RIQ1   B0W1T4   A0A2A3E503   A0A182QDM9   A0A2S2Q6P6   B4I7H3   Q8MLX0   B4QFJ8   A0A0J9U744   A0A2H8TER7   J9K9Z0   A0A182TFP5   A0A084VCP6   A0A087ZY46   A0A026WAY9   F4W994   A0A182GFN3   U4UHB1   A0A182P368   A0A151X8Y4   A0A182VTD2   E2APH5   A0A0L7RCA0   E9J755   A0A1S4GYZ1   A0A182F3A0   A0A151IAC0   W5JE51   Q7Q8C9   A0A226F360   A0A182VNR5   A0A1D2MPH3   R7TF11   V4ALG5   R7T4L4   A0A2P6KSU1   A0A087UZV2   A0A2T7PJ64   R7TBU9   T1KEH1  

PDB

3A3K     E-value=8.7253e-10,     Score=145

KEGG

101739209    K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] | (RefSeq) atrial natriuretic peptide rece

PATHWAY

00230    Purine metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0004383   GO:0004672   GO:0035556   GO:0005524   GO:0007165   GO:0006182   GO:0007168   GO:0005886   GO:0001653   GO:0000166   GO:0016849   GO:0009190   GO:0016787   GO:0005887   GO:0038023   GO:0019934   GO:0006468  

SignalP

Position:   1 - 19,         Likelihood:  0.691846

 

 

Length:

130

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

9.94506

Exp number, first 60 AAs:

5.28285

Total prob of N-in:

0.28882

outside

1  -  130

 

 

Pi

337.044149

Theta

201.747059

Tajima's D

2.110982

CLR

0.383907

CSRT

0.904604769761512

Interpretation

Uncertain