Gene

KWMTBOMO11670

Annotation

Atrial_natriuretic_peptide_receptor_1_[Papilio_xuthus]

Location

Bomo_Chr19(-):11067647-11074492      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Extracellular   Reliability : 1.18 PlasmaMembrane   Reliability : 1.463

CDS

ATGTCTTACTGCCAGTGTCGACTACCTCGCGTCTTCAACAGCATTTTCACGAGATTCGGTTGGTCGCACGTCGCTCTCCTGCTAGACAAGTCGGATCTATTTTCATTAACGGTCGGTAAAAGCCTCGAGTGGGGTCTCAGGAAGCAAGGGGTGCTTAAAGCTGTACGGGAGTTGGACGGGAACGAGCGAGAATCTTGCGACGCTCTACTTCTTGACGTCAGTATGTATGCCCGTGTTGTGATTTTGAGTGTACGTGGATCTCTTGTACGCGAGTTCCTCTTGGCGGCGCACGCTCTCGGCATGACGCGGGGAGACTGGGCTTTTCTCGACGTCGAAATATTTCAGGTAAATATTTTAGAATTCAATGTTAGATGA

Protein

MSYCQCRLPRVFNSIFTRFGWSHVALLLDKSDLFSLTVGKSLEWGLRKQGVLKAVRELDGNERESCDALLLDVSMYARVVILSVRGSLVREFLLAAHALGMTRGDWAFLDVEIFQVNILEFNVR

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Feature

chain  Guanylate cyclase

Uniprot

A0A194QCN7   A0A194QY55   A0A2A4JEQ7   A0A212FAS7   A0A1B6MDH2   A0A1B6EVH7   + More
A0A3Q0JA92   D6WRM6   A0A3L8DR11   A0A1I8QAW1   A0A2P8ZLU6   A0A3Q0JEJ9   A0A2A3E503   A0A182TFP5   A0A1A9VKL9   A0A034VLT6   A0A1B6E8T6   A0A084VCP6   A0A1A9ZVI9   A0A1B0BZE8   A0A1B6JQJ8   A0A1I8MX63   E2B4C6   A0A182KAX1   A0A182NAJ3   E9J755   A0A1B0G3T4   A0A182P368   A0A0L0C030   A0A154P996   A0A034VK64   A0A026WAY9   A0A182X4V8   A0A182IBF2   A0A182RK03   A0A1S4GYZ1   A0A182KYI0   B4LQ69   B4KRH8   K7JAC0   A0A182YMA1   A0A0J7KY59   A0A182MS04   A0A2J7QWW5   A0A151IAC0   A0A087ZY46   A0A151X8Y4   A0A195F339   A0A182QDM9   A0A067RK75   A0A195B5P1   A0A182JJG6   A0A158NDH8   A0A310S5S1   A0A151J3M2   A0A1A9XAD8   E2APH5   A0A1W4V6D9   B0W1T4   A0A2S2Q6P6   A0A182VTD2   B4H4Z8   A0A182VNR5   B4J8X4   A0A182GFN3   Q7Q8C9   A0A0Q9XIU0   A0A0Q9WDQ8   A0A0M4E8Y6   A0A182F3A0   W5JE51   A0A3B0JUU0   A0A0P9BWM0   B3MIB2   B4NN48   Q28X38   A0A0N0BDY8   A0A0J9RIQ1   A0A0Q5W083   A0A0R1DS54   B4I7H3   Q9W2P1   B4P9K3   B3NK16   A0A0J9U744   B4QFJ8   Q8MLX0   A0A1J1I983   A0A2S2PGL0   A0A0L7RCA0   A0A2H8TER7   J9K9Z0   F4W994   A0A1D2MPH3   A0A226F360  

EC Number

4.6.1.2

Pubmed

26354079    22118469    18362917    19820115    30249741    29403074    + More
25348373    24438588    25315136    20798317    21282665    26108605    24508170    12364791    20966253    17994087    20075255    25244985    24845553    21347285    26483478    20920257    23761445    15632085    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    21719571    27289101   

EMBL

KQ459185    KPJ03232.1    KQ460949    KPJ10473.1    NWSH01001857    PCG69903.1    + More
AGBW02009432    OWR50831.1    GEBQ01006038    JAT33939.1    GECZ01027773    JAS41996.1    KQ971354    EFA07684.2    QOIP01000005    RLU22831.1    PYGN01000020    PSN57477.1    KZ288369    PBC26770.1    GAKP01016439    JAC42513.1    GEDC01002962    JAS34336.1    ATLV01010838    KE524620    KFB35740.1    JXJN01023105    GECU01006533    JAT01174.1    GL445549    EFN89474.1    GL768421    EFZ11362.1    CCAG010019265    JRES01001096    KNC25591.1    KQ434829    KZC07740.1    GAKP01016440    GAKP01016438    JAC42512.1    KK107293    EZA53272.1    APCN01000679    AAAB01008944    CH940648    EDW61354.2    CH933808    EDW10404.2    AAZX01000434    AAZX01000435    AAZX01012324    AAZX01016843    LBMM01001953    KMQ95482.1    AXCM01014074    AXCM01014075    NEVH01009413    PNF33087.1    KQ978223    KYM96262.1    KQ982402    KYQ56837.1    KQ981855    KYN34878.1    AXCN02002197    KK852461    KDR23428.1    KQ976598    KYM79590.1    ADTU01001036    ADTU01001037    KQ769179    OAD52914.1    KQ980275    KYN17032.1    GL441542    EFN64674.1    DS231823    EDS26635.1    GGMS01003659    MBY72862.1    CH479210    EDW32834.1    CH916367    EDW01323.1    JXUM01060110    JXUM01060111    JXUM01060112    JXUM01060113    JXUM01060114    KQ562088    KXJ76720.1    EAA10186.4    KRG05220.1    KRF79937.1    CP012524    ALC41271.1    ADMH02001784    ETN61094.1    OUUW01000001    SPP74838.1    CH902619    KPU75902.1    EDV35957.1    CH964282    EDW85787.1    CM000071    EAL26478.3    KQ435847    KOX71134.1    CM002911    KMY95374.1    CH954179    KQS62239.1    CM000158    KRJ99806.1    CH480824    EDW56548.1    AE013599    AAF46649.2    EDW91323.1    EDV55382.1    KMY95375.1    CM000362    EDX07990.1    AAM68187.2    CVRI01000044    CRK96829.1    GGMR01015962    MBY28581.1    KQ414616    KOC68458.1    GFXV01000769    MBW12574.1    ABLF02027323    ABLF02027327    ABLF02027333    ABLF02027334    ABLF02027335    GL888002    EGI69276.1    LJIJ01000725    ODM94989.1    LNIX01000001    OXA63366.1   

Proteomes

UP000053268    UP000053240    UP000218220    UP000007151    UP000079169    UP000007266    + More
UP000279307    UP000095300    UP000245037    UP000242457    UP000075902    UP000078200    UP000030765    UP000092445    UP000092460    UP000095301    UP000008237    UP000075881    UP000075884    UP000092444    UP000075885    UP000037069    UP000076502    UP000053097    UP000076407    UP000075840    UP000075900    UP000075882    UP000008792    UP000009192    UP000002358    UP000076408    UP000036403    UP000075883    UP000235965    UP000078542    UP000005203    UP000075809    UP000078541    UP000075886    UP000027135    UP000078540    UP000075880    UP000005205    UP000078492    UP000092443    UP000000311    UP000192221    UP000002320    UP000075920    UP000008744    UP000075903    UP000001070    UP000069940    UP000249989    UP000007062    UP000092553    UP000069272    UP000000673    UP000268350    UP000007801    UP000007798    UP000001819    UP000053105    UP000008711    UP000002282    UP000001292    UP000000803    UP000000304    UP000183832    UP000053825    UP000007819    UP000007755    UP000094527    UP000198287   

PRIDE

Q9W2P1    Q8MLX0   

Pfam

PF01094   ANF_receptor        + More
PF00211   Guanylate_cyc
PF07714   Pkinase_Tyr
PF05585   DUF1758
PF07701   HNOBA
PF12796   Ank_2

Interpro

IPR001170   ANPR/GUC        + More
IPR001828   ANF_lig-bd_rcpt       
IPR028082   Peripla_BP_I       
IPR029787   Nucleotide_cyclase       
IPR000719   Prot_kinase_dom       
IPR001054   A/G_cyclase       
IPR011009   Kinase-like_dom_sf       
IPR018297   A/G_cyclase_CS       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR008737   Peptidase_asp_put       
IPR011645   HNOB_dom_associated       
IPR020635   Tyr_kinase_cat_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       

SUPFAM

SSF53822   SSF53822        + More
SSF55073   SSF55073       
SSF56112   SSF56112       
SSF48403   SSF48403       

Gene 3D

3.30.70.1230     1.25.40.20    

CDD

cd00204  ANK

ProteinModelPortal

A0A194QCN7   A0A194QY55   A0A2A4JEQ7   A0A212FAS7   A0A1B6MDH2   A0A1B6EVH7   + More
A0A3Q0JA92   D6WRM6   A0A3L8DR11   A0A1I8QAW1   A0A2P8ZLU6   A0A3Q0JEJ9   A0A2A3E503   A0A182TFP5   A0A1A9VKL9   A0A034VLT6   A0A1B6E8T6   A0A084VCP6   A0A1A9ZVI9   A0A1B0BZE8   A0A1B6JQJ8   A0A1I8MX63   E2B4C6   A0A182KAX1   A0A182NAJ3   E9J755   A0A1B0G3T4   A0A182P368   A0A0L0C030   A0A154P996   A0A034VK64   A0A026WAY9   A0A182X4V8   A0A182IBF2   A0A182RK03   A0A1S4GYZ1   A0A182KYI0   B4LQ69   B4KRH8   K7JAC0   A0A182YMA1   A0A0J7KY59   A0A182MS04   A0A2J7QWW5   A0A151IAC0   A0A087ZY46   A0A151X8Y4   A0A195F339   A0A182QDM9   A0A067RK75   A0A195B5P1   A0A182JJG6   A0A158NDH8   A0A310S5S1   A0A151J3M2   A0A1A9XAD8   E2APH5   A0A1W4V6D9   B0W1T4   A0A2S2Q6P6   A0A182VTD2   B4H4Z8   A0A182VNR5   B4J8X4   A0A182GFN3   Q7Q8C9   A0A0Q9XIU0   A0A0Q9WDQ8   A0A0M4E8Y6   A0A182F3A0   W5JE51   A0A3B0JUU0   A0A0P9BWM0   B3MIB2   B4NN48   Q28X38   A0A0N0BDY8   A0A0J9RIQ1   A0A0Q5W083   A0A0R1DS54   B4I7H3   Q9W2P1   B4P9K3   B3NK16   A0A0J9U744   B4QFJ8   Q8MLX0   A0A1J1I983   A0A2S2PGL0   A0A0L7RCA0   A0A2H8TER7   J9K9Z0   F4W994   A0A1D2MPH3   A0A226F360  

PDB

1JDP     E-value=1.69626e-06,     Score=117

KEGG

101739209    K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] | (RefSeq) atrial natriuretic peptide rece

GO

GO:0016021   GO:0035556   GO:0004383   GO:0004672   GO:0005524   GO:0007165   GO:0006182   GO:0007168   GO:0005886   GO:0001653   GO:0000166   GO:0016849   GO:0009190   GO:0004713   GO:0005887   GO:0038023   GO:0019934   GO:0006468  

Length:

124

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.30269

Exp number, first 60 AAs:

0.04654

Total prob of N-in:

0.42262

outside

1  -  124

 

 

Pi

186.624033

Theta

154.211565

Tajima's D

0.215371

CLR

0

CSRT

0.431678416079196

Interpretation

Uncertain