Gene

KWMTBOMO11669

Annotation

PREDICTED:_atrial_natriuretic_peptide_receptor_1_[Bombyx_mori]

Location

Bomo_Chr19(-):11057858-11064612      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Cytoplasmic   Reliability : 1.745 Nuclear   Reliability : 1.224

CDS

ATGGCCCTGAACGAGACATTGACTGAAGGCGGAGACATCCGAGACGGAAGGAATATAACTCGGCGTATGTGGGGCCGGGATTTTTATGGCATCACTGGACACGTCCGTATAGACAAAGTAGGCGACAGAGATGCTGACTACGCGATTTTGGATTTGGATCCGGTCACCGGGAAATTTGAGGTTGTGGCGTTCTACCACGGTCTGAACAGTAGCTACAAGCCGGTACCTGGTAAAGCCATCCACTGGCCGGGAGGTAGGCGTGGACCACCGCCTGATACTCCAAGATGCGGGTTTTTGGGCACCGATCCTACGTGTCAGGGAGGTAATTAA

Protein

MALNETLTEGGDIRDGRNITRRMWGRDFYGITGHVRIDKVGDRDADYAILDLDPVTGKFEVVAFYHGLNSSYKPVPGKAIHWPGGRRGPPPDTPRCGFLGTDPTCQGGN

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Feature

chain  Guanylate cyclase

Uniprot

A0A212FAS7   A0A194QY55   A0A2A4JEQ7   A0A194QCN7   K7JAC0   Q7Q8C9   + More
A0A182IBF2   A0A182X4V8   A0A182MS04   A0A182RK03   A0A182KAX1   A0A154P996   A0A0L7RCA0   A0A084VCP6   A0A2A3E503   A0A3L8DR11   A0A087ZY46   A0A026WAY9   A0A182VTD2   A0A182SWL6   A0A0N0BDY8   A0A182KYI0   E9J755   A0A151IAC0   A0A2J7QWW5   A0A0M4E8Y6   E2B4C6   A0A182YMA1   A0A3Q0JA92   A0A182QDM9   A0A067RK75   A0A182VNR5   A0A310S5S1   B3MIB2   E2APH5   A0A195B5P1   A0A151X8Y4   A0A195F339   A0A158NDH8   A0A1B0G3T4   A0A1S4GYZ1   A0A182TFP5   F4W994   A0A3B0JUU0   A0A151J3M2   Q28X38   A0A182NAJ3   B4H4Z8   B4NN48   B0W1T4   A0A182F3A0   D6WRM6   W5JE51   A0A336KPL4   A0A182P368   B4I7H3   A0A0J9U744   B4P9K3   B3NK16   A0A1W4V6D9   Q8MLX0   A0A034VLT6   A0A1J1I983   B4J8X4   A0A034VK64   B4LQ69   B4KRH8   A0A1A9VKL9   A0A1A9ZVI9   A0A1B0BZE8   B4QFJ8   A0A0L0C030   A0A2P8ZLU6   A0A1I8MX63   A0A2S2Q6P6   J9K9Z0   A0A182GFN3   A0A2H8TER7   A0A2T7PRV2   A0A2C9JTI9   A0A3S0Z971   V4AZ64   A0A164WKJ2   A0A0P5A7T8   A0A0P5WZ09   A0A0N7ZW91   E9H6U6   A0A0P5V9T5   A0A0P5E5G3   A0A0P5C8M5   A0A0P5YV34  

EC Number

4.6.1.2

Pubmed

22118469    26354079    20075255    12364791    24438588    30249741    + More
24508170    20966253    21282665    20798317    25244985    24845553    17994087    21347285    21719571    15632085    18362917    19820115    20920257    23761445    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25348373    26108605    29403074    25315136    26483478    15562597    23254933    21292972   

EMBL

AGBW02009432    OWR50831.1    KQ460949    KPJ10473.1    NWSH01001857    PCG69903.1    + More
KQ459185    KPJ03232.1    AAZX01000434    AAZX01000435    AAZX01012324    AAZX01016843    AAAB01008944    EAA10186.4    APCN01000679    AXCM01014074    AXCM01014075    KQ434829    KZC07740.1    KQ414616    KOC68458.1    ATLV01010838    KE524620    KFB35740.1    KZ288369    PBC26770.1    QOIP01000005    RLU22831.1    KK107293    EZA53272.1    KQ435847    KOX71134.1    GL768421    EFZ11362.1    KQ978223    KYM96262.1    NEVH01009413    PNF33087.1    CP012524    ALC41271.1    GL445549    EFN89474.1    AXCN02002197    KK852461    KDR23428.1    KQ769179    OAD52914.1    CH902619    EDV35957.1    GL441542    EFN64674.1    KQ976598    KYM79590.1    KQ982402    KYQ56837.1    KQ981855    KYN34878.1    ADTU01001036    ADTU01001037    CCAG010019265    GL888002    EGI69276.1    OUUW01000001    SPP74838.1    KQ980275    KYN17032.1    CM000071    EAL26478.3    CH479210    EDW32834.1    CH964282    EDW85787.1    DS231823    EDS26635.1    KQ971354    EFA07684.2    ADMH02001784    ETN61094.1    UFQS01000670    UFQT01000670    SSX05992.1    SSX26349.1    CH480824    EDW56548.1    CM002911    KMY95375.1    CM000158    EDW91323.1    CH954179    EDV55382.1    AE013599    AAM68187.2    GAKP01016439    JAC42513.1    CVRI01000044    CRK96829.1    CH916367    EDW01323.1    GAKP01016440    GAKP01016438    JAC42512.1    CH940648    EDW61354.2    CH933808    EDW10404.2    JXJN01023105    CM000362    EDX07990.1    JRES01001096    KNC25591.1    PYGN01000020    PSN57477.1    GGMS01003659    MBY72862.1    ABLF02027323    ABLF02027327    ABLF02027333    ABLF02027334    ABLF02027335    JXUM01060110    JXUM01060111    JXUM01060112    JXUM01060113    JXUM01060114    KQ562088    KXJ76720.1    GFXV01000769    MBW12574.1    PZQS01000002    PVD36154.1    RQTK01001090    RUS72264.1    KB200718    ESP00406.1    LRGB01001200    KZS13348.1    GDIP01206410    JAJ16992.1    GDIP01079976    JAM23739.1    GDIP01206409    JAJ16993.1    GL732598    EFX72574.1    GDIP01102467    JAM01248.1    GDIP01152576    JAJ70826.1    GDIP01190112    JAJ33290.1    GDIP01052684    JAM51031.1   

Proteomes

UP000007151    UP000053240    UP000218220    UP000053268    UP000002358    UP000007062    + More
UP000075840    UP000076407    UP000075883    UP000075900    UP000075881    UP000076502    UP000053825    UP000030765    UP000242457    UP000279307    UP000005203    UP000053097    UP000075920    UP000075901    UP000053105    UP000075882    UP000078542    UP000235965    UP000092553    UP000008237    UP000076408    UP000079169    UP000075886    UP000027135    UP000075903    UP000007801    UP000000311    UP000078540    UP000075809    UP000078541    UP000005205    UP000092444    UP000075902    UP000007755    UP000268350    UP000078492    UP000001819    UP000075884    UP000008744    UP000007798    UP000002320    UP000069272    UP000007266    UP000000673    UP000075885    UP000001292    UP000002282    UP000008711    UP000192221    UP000000803    UP000183832    UP000001070    UP000008792    UP000009192    UP000078200    UP000092445    UP000092460    UP000000304    UP000037069    UP000245037    UP000095301    UP000007819    UP000069940    UP000249989    UP000245119    UP000076420    UP000271974    UP000030746    UP000076858    UP000000305   

PRIDE

Q8MLX0   

Pfam

PF00211   Guanylate_cyc        + More
PF07714   Pkinase_Tyr
PF01094   ANF_receptor
PF05585   DUF1758
PF12796   Ank_2
PF07701   HNOBA
PF00149   Metallophos
PF00069   Pkinase

Interpro

IPR000719   Prot_kinase_dom        + More
IPR029787   Nucleotide_cyclase       
IPR028082   Peripla_BP_I       
IPR001054   A/G_cyclase       
IPR001170   ANPR/GUC       
IPR011009   Kinase-like_dom_sf       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR018297   A/G_cyclase_CS       
IPR008737   Peptidase_asp_put       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       
IPR011645   HNOB_dom_associated       
IPR020635   Tyr_kinase_cat_dom       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR041871   MPP_TMEM62       
IPR029052   Metallo-depent_PP-like       

SUPFAM

SSF56112   SSF56112        + More
SSF55073   SSF55073       
SSF53822   SSF53822       
SSF48403   SSF48403       

Gene 3D

3.30.70.1230     1.25.40.20     3.60.21.10    

CDD

cd00204  ANK
cd07401  MPP_TMEM62_N

ProteinModelPortal

A0A212FAS7   A0A194QY55   A0A2A4JEQ7   A0A194QCN7   K7JAC0   Q7Q8C9   + More
A0A182IBF2   A0A182X4V8   A0A182MS04   A0A182RK03   A0A182KAX1   A0A154P996   A0A0L7RCA0   A0A084VCP6   A0A2A3E503   A0A3L8DR11   A0A087ZY46   A0A026WAY9   A0A182VTD2   A0A182SWL6   A0A0N0BDY8   A0A182KYI0   E9J755   A0A151IAC0   A0A2J7QWW5   A0A0M4E8Y6   E2B4C6   A0A182YMA1   A0A3Q0JA92   A0A182QDM9   A0A067RK75   A0A182VNR5   A0A310S5S1   B3MIB2   E2APH5   A0A195B5P1   A0A151X8Y4   A0A195F339   A0A158NDH8   A0A1B0G3T4   A0A1S4GYZ1   A0A182TFP5   F4W994   A0A3B0JUU0   A0A151J3M2   Q28X38   A0A182NAJ3   B4H4Z8   B4NN48   B0W1T4   A0A182F3A0   D6WRM6   W5JE51   A0A336KPL4   A0A182P368   B4I7H3   A0A0J9U744   B4P9K3   B3NK16   A0A1W4V6D9   Q8MLX0   A0A034VLT6   A0A1J1I983   B4J8X4   A0A034VK64   B4LQ69   B4KRH8   A0A1A9VKL9   A0A1A9ZVI9   A0A1B0BZE8   B4QFJ8   A0A0L0C030   A0A2P8ZLU6   A0A1I8MX63   A0A2S2Q6P6   J9K9Z0   A0A182GFN3   A0A2H8TER7   A0A2T7PRV2   A0A2C9JTI9   A0A3S0Z971   V4AZ64   A0A164WKJ2   A0A0P5A7T8   A0A0P5WZ09   A0A0N7ZW91   E9H6U6   A0A0P5V9T5   A0A0P5E5G3   A0A0P5C8M5   A0A0P5YV34  

PDB

3A3K     E-value=5.98252e-20,     Score=233

KEGG

101739209    K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] | (RefSeq) atrial natriuretic peptide rece

GO

GO:0004383   GO:0004672   GO:0035556   GO:0016021   GO:0005524   GO:0006182   GO:0007165   GO:0007168   GO:0001653   GO:0005886   GO:0000166   GO:0004713   GO:0016787   GO:0038023   GO:0005887   GO:0006468   GO:0019934  

Length:

109

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00137

Exp number, first 60 AAs:

0.00078

Total prob of N-in:

0.12413

outside

1  -  109

 

 

Pi

192.689028

Theta

187.526817

Tajima's D

-1.706128

CLR

0.351523

CSRT

0.0349482525873706

Interpretation

Uncertain