Gene

KWMTBOMO11668

Pre Gene Modal

BGIBMGA003982

Annotation

PREDICTED:_atrial_natriuretic_peptide_receptor_1_[Bombyx_mori]

Location

Bomo_Chr19(-):11038074-11054922      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Cytoplasmic   Reliability : 1.734 PlasmaMembrane   Reliability : 1.063

CDS

ATGACAGACGCTACTGAATTTCCATATAATTTTCAGCAGGCTCGAATCGACGCGGAGTTAAACAACATAGCGTGGAGGGTGCGCCCTGAGGAAGTACTCGTCGAAGTTGGCACTGGACTGGGGGCGAGCCCGGCCTTACACAACATCAACGAGGTCCTTAAGCTTTCATTGAGCTGGACCGCAAGAGGAAGTACAGCAGCCACCAGTCTTACTGCATCTCCATCGGTCACTCTGTCTTCGTTTACCGTCGGCCTCTACAAGGGCAATAGGGTTGCAGTCAAAAAAATACACAGAAAGAAACTCGACTTGAATAAAAAACTAATCTGGGAGATTAAACAGGCTCGAAACGTTTCCCACGAGAATACGGCACGTTTTATCGGAGCCTGTGTGGATTGTCCCCTAGTCTTTGTGCTCACTGAGTATTGCCCCAAAGGATCCCTGAAGGATGTACTCGCTAACGATGAGCTACAATTGGACTGGAATTTCAGGACTTCACTTGTCCATGACATTGTTCAGGGAATGTGCTATCTTCATGGCGGACTCGGAGCTCACGGGAAGCTCCGATCTTCGAACTGTCTCATCGATGGACGTTTCGTGCTCAAGATATCCGATTTCGGACTTAATGCGCTTTGCACGCCAACAGATTTGATCAAGGACGACATTTATTATTACAAATTGCTTTGGACAGCACCTGAGTTGATAGCTGGGAGCGTTTACCCAGGGGCAGTCTCTTCGCTGAAGGGGGACGTCTACAGTTTTGGAATAATATTGGAAGAGATCGTCGTCAGAGCTGGACCTTTCCACCATTATACTACAACTGTGTCCAATAAAGAGATAGTGACACGTGTTTGTGCCCGAGAGTCACCGCCGTTCCGGCCGGTGGTGGGCGTCGGAGAAGTCACAGCTGGAGGCGGAGGAGGCTCGGCGTTGGAACTACTGGAGTTGGCTGCGAGGTGCTGGGCTGAACCACCTGACGATAGGCCGAGCTTCGACACTATCAACGCTAATTATATCAAGGGGTACTGCGACAATCTTATGGATGATTTGCTGCGGCGTATGGAACAATACGCGAACAATCTCGAATCTTTGGTCGAAGAGAAAACTGAACAGCTGTCGTTGGAAAAGAGGCGCTCTGAAGAATTACTGTATCAAGTTTTACCGAGACCCGTGGCTCAGCAATTAATGGCCGGTGAAGTGGTACAACCAGAGAGCTTCGAGTGCGTCACGGTTTACTTCAGCGACATAGTCGGTTTCACGGAGCTCTGCGCGGCCTCCACTCCCATGCAAGTTGTGGATCTTTTGAACGACTTGTACAGCACATTCGACAGAATCATCGGTTTTTATGATGTTTATAAGGTCGAAACAATAGGAGACGCCTACATGGTTGTGTCTGGCCTGCCCGAGAGGAACGGCGACCTTCACGCAAGAGAAATATGCTTAATGGCGCTTGCCATAGTCGACGCAGTCAGGGGCTTCGTTGTCCGTCACCGGCCCGCGCACCGACTCGAGGTCCGCGTTGGTGTTCACTCCGGTCCGGTTTGTGCCGGCGTGGTGGGTGTTAAGATGCCCCATTACTGCCTTTTTGGGGATACCGTTAACACCGCAAGTAGAATGGAATCTACAGGCCAACCCCTCCGTATCCATTTGAGTGAGAACACACGTGTGCTCCTGGAACAATGGGGAACATTCATAGTGGAGCGTCGCGGCGAGGTGGAGTTGAAGGGTCGGGGACGGATGTTGACTCACTGGCTGCTGCAGTGCTCTGAGCCAGAGACCAGACCTCACTGCCAAAGTCCCCAGCAGCCTCCGCAGTATCCTATACTGTTCCCGACCTTACCTCCTGTGTCTATACAGGTCCCTTACTTAGTTGTCGAGCCCCCCACAATGGCTGCCTGA

Protein

MTDATEFPYNFQQARIDAELNNIAWRVRPEEVLVEVGTGLGASPALHNINEVLKLSLSWTARGSTAATSLTASPSVTLSSFTVGLYKGNRVAVKKIHRKKLDLNKKLIWEIKQARNVSHENTARFIGACVDCPLVFVLTEYCPKGSLKDVLANDELQLDWNFRTSLVHDIVQGMCYLHGGLGAHGKLRSSNCLIDGRFVLKISDFGLNALCTPTDLIKDDIYYYKLLWTAPELIAGSVYPGAVSSLKGDVYSFGIILEEIVVRAGPFHHYTTTVSNKEIVTRVCARESPPFRPVVGVGEVTAGGGGGSALELLELAARCWAEPPDDRPSFDTINANYIKGYCDNLMDDLLRRMEQYANNLESLVEEKTEQLSLEKRRSEELLYQVLPRPVAQQLMAGEVVQPESFECVTVYFSDIVGFTELCAASTPMQVVDLLNDLYSTFDRIIGFYDVYKVETIGDAYMVVSGLPERNGDLHAREICLMALAIVDAVRGFVVRHRPAHRLEVRVGVHSGPVCAGVVGVKMPHYCLFGDTVNTASRMESTGQPLRIHLSENTRVLLEQWGTFIVERRGEVELKGRGRMLTHWLLQCSEPETRPHCQSPQQPPQYPILFPTLPPVSIQVPYLVVEPPTMAA

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Feature

chain  Guanylate cyclase

Uniprot

A0A212FAS7   H9J395   A0A194QCG2   A0A194QY55   A0A2H1W706   A0A1I8MX63   + More
D6WRM6   A0A0L0C030   A0A1B0G3T4   A0A067RK75   A0A1A9X300   A0A1A9ZVI9   A0A1A9VKL9   A0A1A9XAD8   A0A1B0BZE8   A0A084VCP6   A0A182IBF2   W5JE51   A0A182P368   A0A182X4V8   A0A182VTD2   A0A1S4GYZ1   A0A182KYH9   A0A182RK03   A0A182J7G0   A0A182KAX1   A0A2A4JEQ7   B0W1T4   A0A182NAJ3   A0A336KPL4   A0A1B6MF04   A0A182GFN3   A0A1S4FTB9   A0A026WAY9   A0A154P996   A0A087ZY46   A0A2A3E503   A0A3L8DR11   A0A182T9T2   A0A310S5S1   A0A151IAC0   A0A195F339   A0A0N0BDY8   J9K9Z0   A0A2S2Q6P6   F4W994   A0A151X8Y4   A0A151J3M2   A0A195B5P1   A0A158NDH8   E9J755   A0A0L7RCA0   A0A182UPL3   A0A182UJ41   A0A182Q5H2   Q7Q8C9   A0A0J9RIQ1   B4NN48   Q9W2P1   A0A0R1DS54   A0A0Q5W083   A0A3B0JUU0   B4QFJ8   Q28X38   Q8MLX0   B4H4Z8   B4P9K3   B4I7H3   A0A0J9U744   B3NK16   A0A0P9BWM0   A0A1J1I983   B3MIB2   A0A1W4V6D9   K7JAC0   E2APH5   A0A0Q9WDQ8   B4J8X4   A0A0Q9XIU0   B4LQ69   B4KRH8   Q16QE2   A0A0M4E8Y6   A0A2P8ZLU6   F1PMP1   A0A3Q7SA38   F1SFW3   A0A2Y9FWK3   A0A2Y9MCI5   A0A2Y9LZG2   A0A2Y9M7N4   A0A341BMM6   A0A340XGE2   L9JAD8   M3YA30   A0A3Q7UWT7   M3VZ19   A0A383ZTZ7   E1BN71   A0A2U3W4P9  

EC Number

4.6.1.2

Pubmed

22118469    19121390    26354079    25315136    18362917    19820115    + More
26108605    24845553    24438588    20920257    23761445    12364791    20966253    26483478    17510324    24508170    30249741    21719571    21347285    21282665    22936249    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    17550304    15632085    20075255    20798317    29403074    16341006    23385571    17975172    19393038   

EMBL

AGBW02009432    OWR50831.1    BABH01021723    KQ459185    KPJ03233.1    KQ460949    + More
KPJ10473.1    ODYU01006676    SOQ48736.1    KQ971354    EFA07684.2    JRES01001096    KNC25591.1    CCAG010019265    KK852461    KDR23428.1    JXJN01023105    ATLV01010838    KE524620    KFB35740.1    APCN01000679    ADMH02001784    ETN61094.1    AAAB01008944    NWSH01001857    PCG69903.1    DS231823    EDS26635.1    UFQS01000670    UFQT01000670    SSX05992.1    SSX26349.1    GEBQ01005483    JAT34494.1    JXUM01060110    JXUM01060111    JXUM01060112    JXUM01060113    JXUM01060114    KQ562088    KXJ76720.1    KK107293    EZA53272.1    KQ434829    KZC07740.1    KZ288369    PBC26770.1    QOIP01000005    RLU22831.1    KQ769179    OAD52914.1    KQ978223    KYM96262.1    KQ981855    KYN34878.1    KQ435847    KOX71134.1    ABLF02027323    ABLF02027327    ABLF02027333    ABLF02027334    ABLF02027335    GGMS01003659    MBY72862.1    GL888002    EGI69276.1    KQ982402    KYQ56837.1    KQ980275    KYN17032.1    KQ976598    KYM79590.1    ADTU01001036    ADTU01001037    GL768421    EFZ11362.1    KQ414616    KOC68458.1    AXCN02002197    EAA10186.4    CM002911    KMY95374.1    CH964282    EDW85787.1    AE013599    AAF46649.2    CM000158    KRJ99806.1    CH954179    KQS62239.1    OUUW01000001    SPP74838.1    CM000362    EDX07990.1    CM000071    EAL26478.3    AAM68187.2    CH479210    EDW32834.1    EDW91323.1    CH480824    EDW56548.1    KMY95375.1    EDV55382.1    CH902619    KPU75902.1    CVRI01000044    CRK96829.1    EDV35957.1    AAZX01000434    AAZX01000435    AAZX01012324    AAZX01016843    GL441542    EFN64674.1    CH940648    KRF79937.1    CH916367    EDW01323.1    CH933808    KRG05220.1    EDW61354.2    EDW10404.2    CH477751    EAT36610.1    CP012524    ALC41271.1    PYGN01000020    PSN57477.1    AAEX03005359    AEMK02000022    KB321128    ELW47323.1    AEYP01100003    AANG04002876   

Proteomes

UP000007151    UP000005204    UP000053268    UP000053240    UP000095301    UP000007266    + More
UP000037069    UP000092444    UP000027135    UP000091820    UP000092445    UP000078200    UP000092443    UP000092460    UP000030765    UP000075840    UP000000673    UP000075885    UP000076407    UP000075920    UP000075882    UP000075900    UP000075880    UP000075881    UP000218220    UP000002320    UP000075884    UP000069940    UP000249989    UP000053097    UP000076502    UP000005203    UP000242457    UP000279307    UP000075901    UP000078542    UP000078541    UP000053105    UP000007819    UP000007755    UP000075809    UP000078492    UP000078540    UP000005205    UP000053825    UP000075903    UP000075902    UP000075886    UP000007062    UP000007798    UP000000803    UP000002282    UP000008711    UP000268350    UP000000304    UP000001819    UP000008744    UP000001292    UP000007801    UP000183832    UP000192221    UP000002358    UP000000311    UP000008792    UP000001070    UP000009192    UP000008820    UP000092553    UP000245037    UP000002254    UP000286640    UP000008227    UP000248484    UP000248483    UP000252040    UP000265300    UP000011518    UP000000715    UP000286642    UP000011712    UP000261681    UP000009136    UP000245340   

PRIDE

H9J395    Q9W2P1    Q8MLX0    F1SFW3   

Pfam

PF00211   Guanylate_cyc        + More
PF07714   Pkinase_Tyr
PF01094   ANF_receptor
PF07701   HNOBA
PF05585   DUF1758
PF00149   Metallophos
PF12796   Ank_2

Interpro

IPR000719   Prot_kinase_dom        + More
IPR029787   Nucleotide_cyclase       
IPR028082   Peripla_BP_I       
IPR001054   A/G_cyclase       
IPR001170   ANPR/GUC       
IPR011009   Kinase-like_dom_sf       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR018297   A/G_cyclase_CS       
IPR020635   Tyr_kinase_cat_dom       
IPR011645   HNOB_dom_associated       
IPR008737   Peptidase_asp_put       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR041871   MPP_TMEM62       
IPR029052   Metallo-depent_PP-like       
IPR036770   Ankyrin_rpt-contain_sf       
IPR020683   Ankyrin_rpt-contain_dom       
IPR002110   Ankyrin_rpt       

SUPFAM

SSF56112   SSF56112        + More
SSF55073   SSF55073       
SSF53822   SSF53822       
SSF48403   SSF48403       

Gene 3D

3.30.70.1230     3.60.21.10     1.25.40.20    

CDD

cd07401  MPP_TMEM62_N
cd00204  ANK

ProteinModelPortal

A0A212FAS7   H9J395   A0A194QCG2   A0A194QY55   A0A2H1W706   A0A1I8MX63   + More
D6WRM6   A0A0L0C030   A0A1B0G3T4   A0A067RK75   A0A1A9X300   A0A1A9ZVI9   A0A1A9VKL9   A0A1A9XAD8   A0A1B0BZE8   A0A084VCP6   A0A182IBF2   W5JE51   A0A182P368   A0A182X4V8   A0A182VTD2   A0A1S4GYZ1   A0A182KYH9   A0A182RK03   A0A182J7G0   A0A182KAX1   A0A2A4JEQ7   B0W1T4   A0A182NAJ3   A0A336KPL4   A0A1B6MF04   A0A182GFN3   A0A1S4FTB9   A0A026WAY9   A0A154P996   A0A087ZY46   A0A2A3E503   A0A3L8DR11   A0A182T9T2   A0A310S5S1   A0A151IAC0   A0A195F339   A0A0N0BDY8   J9K9Z0   A0A2S2Q6P6   F4W994   A0A151X8Y4   A0A151J3M2   A0A195B5P1   A0A158NDH8   E9J755   A0A0L7RCA0   A0A182UPL3   A0A182UJ41   A0A182Q5H2   Q7Q8C9   A0A0J9RIQ1   B4NN48   Q9W2P1   A0A0R1DS54   A0A0Q5W083   A0A3B0JUU0   B4QFJ8   Q28X38   Q8MLX0   B4H4Z8   B4P9K3   B4I7H3   A0A0J9U744   B3NK16   A0A0P9BWM0   A0A1J1I983   B3MIB2   A0A1W4V6D9   K7JAC0   E2APH5   A0A0Q9WDQ8   B4J8X4   A0A0Q9XIU0   B4LQ69   B4KRH8   Q16QE2   A0A0M4E8Y6   A0A2P8ZLU6   F1PMP1   A0A3Q7SA38   F1SFW3   A0A2Y9FWK3   A0A2Y9MCI5   A0A2Y9LZG2   A0A2Y9M7N4   A0A341BMM6   A0A340XGE2   L9JAD8   M3YA30   A0A3Q7UWT7   M3VZ19   A0A383ZTZ7   E1BN71   A0A2U3W4P9  

PDB

3UVJ     E-value=3.02824e-39,     Score=408

KEGG

101739209    K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] | (RefSeq) atrial natriuretic peptide rece

GO

GO:0004383   GO:0004672   GO:0035556   GO:0016021   GO:0005524   GO:0004713   GO:0007165   GO:0006182   GO:0007168   GO:0005886   GO:0001653   GO:0016787   GO:0000166   GO:0005887   GO:0038023   GO:0019934   GO:0006468   GO:0016941   GO:0043235   GO:0017046   GO:0009190   GO:0016849   GO:0006811   GO:0016020   GO:0043564   GO:0006418   GO:0003824  

Length:

631

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.18928

Exp number, first 60 AAs:

0.00175

Total prob of N-in:

0.00412

outside

1  -  631

 

 

Pi

277.955847

Theta

180.391712

Tajima's D

1.736312

CLR

0.289547

CSRT

0.837058147092645

Interpretation

Uncertain