Gene

KWMTBOMO11594  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004102

Annotation

PREDICTED:_peptidyl-prolyl_cis-trans_isomerase_FKBP8_isoform_X2_[Papilio_machaon]

Location

Bomo_Chr19(+):9361488-9368230      View in EpiBrowser

Full name

Peptidylprolyl isomerase      

Location in the cell

Cytoplasmic   Reliability : 2.624

CDS

ATGAGTGAAGAAAGCAAAGCTTTGACGGACAAGTCTGAAAGCAGCTCTTTCGAAGACTTAGCGGCTGCGGCTGCTGAGGAGATCGAGGAAGCGAAACTTGCCGAAGCTGCCGCAGCAGAGAAGGAAAAATCCCCAGAAGTAAAGAATGACGAATGGCAAGATGTTCTTGGGTCCGGAGCTCTGCTTAAAAAGATATTGAAACAAGGGGATGAAATATCTGGATCCAGACCACAAAGAGGGGACATATGCAGAATCAGCTATGAACTCAAAATAAAAGACAGTAACAACATTGTGGAGAAAAGAGATCAGATAAAAATATATTTAGGAGACAATGAGGTATTGCAAGGTTTGGACCTAGCATTAACTTTAATGTACAGAGGTGAGGAATGTATTTTGCAACTTGCTCCAAGATTTGCCTATGGAGAAATGGGACTTAAACCAGGTGAGAGCCTTGGATTAGTCGGACAGTGTGATGAACCCAAGTATAAAGGACCTATTATTGGACCAGACACATGGCTTGAAGCCAAATTAGTGCTGCATGATTGGTCAGAAGAACCTGAACACGATGTATTGTCAATAGCGGAAAAAATGGAAATCGGAATTCGTCGTAGAGCCCGCGGTAACTGGTGGTACGGTCGTGATGAACCACAACTAGCGGTGCAGCTATATCGGAGAGCTCTCGACATTCTGGACGAAAGCGAAGGAGGGATCACTGATCCCACGCCGTCTGGGGAACTCACATTCGCTAACCAGGCACTGAAAGAGTTGCTGGATGAACGACTCAGGGTTCATAACAACATGGCTGCTGCTCAACTCAAGGCCGGAGCTTATGAAGCTGCTTTACAGGCCGTAACCAGAGTACTTTCATGTCAACCGAAAAACGCTAAAGCTCTTTATCGCAAATCACGCATTCTATCTGCGATGGGACGGAACCCTGAAGCCCTGGAGGCAGCTAAAGCAGCGGCGGCCGCAGCCCCCGAGGATACTGGTGCTAAAAAAGAATTACAACGATGCGAACAAAGAGCTTCTAGGGATCGTTCTGTGGAAAGGAAACTGGCTAAACGTATGCTGGGCACTACTGACGTGTCGGCGAAAAGCGATGCACCCTCTCCCGATAAGAAACCTTCCAGGTCTAAGATCCTAGTGTGGGGCTCGCTTCTGCTCAGCTTGTTGGTGGGTGTCGCCAGCGTCCTCGTATACAGATATAAAATGCAGGCGCACTGA

Protein

MSEESKALTDKSESSSFEDLAAAAAEEIEEAKLAEAAAAEKEKSPEVKNDEWQDVLGSGALLKKILKQGDEISGSRPQRGDICRISYELKIKDSNNIVEKRDQIKIYLGDNEVLQGLDLALTLMYRGEECILQLAPRFAYGEMGLKPGESLGLVGQCDEPKYKGPIIGPDTWLEAKLVLHDWSEEPEHDVLSIAEKMEIGIRRRARGNWWYGRDEPQLAVQLYRRALDILDESEGGITDPTPSGELTFANQALKELLDERLRVHNNMAAAQLKAGAYEAALQAVTRVLSCQPKNAKALYRKSRILSAMGRNPEALEAAKAAAAAAPEDTGAKKELQRCEQRASRDRSVERKLAKRMLGTTDVSAKSDAPSPDKKPSRSKILVWGSLLLSLLVGVASVLVYRYKMQAH

Catalytic Activity

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Uniprot

H9J3L5   A0A194QCV5   A0A3S2LJ00   A0A2A4JBM8   A0A2A4JCM2   A0A2H1V5V9   + More
A0A212EW45   A0A1E1WQF4   A0A194R188   A0A0L7KZM2   A0A1B6CIU3   A0A067R311   A0A023EQ01   A0A2J7RJX8   U5EVG1   A0A224XIY8   A0A232FL82   A0A1S4FVM5   Q16MK5   A0A069DT63   A0A1S4FVT6   K7JJZ4   E2C4I6   Q16MK6   A0A0P4VRE9   A0A023F1H6   A0A1Y1KQQ1   A0A1Y1KRE4   D6WQV5   A0A2R7X2F8   T1HDK6   A0A0K8TPX4   A0A161ML76   A0A1W4WGY4   A0A1W4W6J4   A0A310SUB3   A0A1J1IEC5   A0A088A5M5   A0A1Q3F7K8   A0A1Q3F7L9   A0A1Q3F7H5   A0A182UVC9   A0A2A3E531   A0A182X4J8   Q7PI62   A0A182TWS1   A0A348G6B6   A0A182I4J5   B0WD01   A0A154PUR8   A0A182R965   A0A0A9YRZ0   W5J8E1   A0A0J7KMC0   A0A2M4BPR3   A0A2M4AAM2   A0A182PMV5   A0A1B0GJM0   A0A182JU29   A0A0L7R2M9   A0A2M3Z3F8   A0A182FGF4   A0A1L8DTW8   A0A1B6JU69   A0A2M4BQM1   A0A2M4A951   A0A0K8TJ23   A0A1I8MHG7   A0A1I8PY78   J3JVI7   A0A2M3Z374   A0A1L8DTN4   A0A182QGN6   A0A182NI90   A0A2M3ZGY7   A0A182LUU9   A0A1L8ECL2   A0A1L8DTP9   T1PC14   A0A182WBQ0   A0A182IXF5   A0A1L8ECM2   A0A1B6FC90   E0VH54   T1DHC7   A0A182Y2J2   A0A0K8W9Z2   A0A0P5HR46   A0A0P6DA46   A0A0N8CKH4   A0A0P5LA10   W8AHP7   A0A0P5RR79   A0A0P5LEB9   A0A0N8BJ23  

EC Number

5.2.1.8

Pubmed

19121390    26354079    22118469    26227816    24845553    24945155    + More
26483478    28648823    17510324    26334808    20075255    20798317    27129103    25474469    28004739    18362917    19820115    26369729    12364791    14747013    17210077    25401762    26823975    20920257    23761445    25315136    22516182    20566863    25244985    24495485   

EMBL

BABH01021572    KQ459185    KPJ03297.1    RSAL01000096    RVE47704.1    NWSH01001992    + More
PCG69497.1    PCG69496.1    ODYU01000850    SOQ36235.1    AGBW02012080    OWR45712.1    GDQN01001846    GDQN01000382    JAT89208.1    JAT90672.1    KQ461073    KPJ09606.1    JTDY01004149    KOB68526.1    GEDC01028241    GEDC01023902    GEDC01020126    GEDC01001016    JAS09057.1    JAS13396.1    JAS17172.1    JAS36282.1    KK853041    KDR12172.1    JXUM01000446    GAPW01001971    JAC11627.1    NEVH01002983    PNF41142.1    GANO01003420    JAB56451.1    GFTR01005412    JAW11014.1    NNAY01000089    OXU31097.1    CH477859    EAT35561.1    GBGD01001978    JAC86911.1    GL452471    EFN77170.1    EAT35560.1    GDKW01002985    JAI53610.1    GBBI01003846    JAC14866.1    GEZM01080890    JAV62005.1    GEZM01080889    JAV62006.1    KQ971351    EFA06496.1    KK856469    PTY25841.1    ACPB03003322    ACPB03003323    GDAI01001422    JAI16181.1    GEMB01002508    JAS00678.1    KQ760116    OAD61952.1    CVRI01000047    CRK98122.1    GFDL01011518    JAV23527.1    GFDL01011490    JAV23555.1    GFDL01011525    JAV23520.1    KZ288400    PBC26279.1    AAAB01008960    EAA44266.3    FX986032    BBF97989.1    APCN01002316    DS231892    EDS44076.1    KQ435178    KZC14950.1    GBHO01025269    GBHO01012453    GBHO01009736    GBHO01009735    GDHC01019141    GDHC01011628    JAG18335.1    JAG31151.1    JAG33868.1    JAG33869.1    JAP99487.1    JAQ07001.1    ADMH02002104    ETN59059.1    LBMM01005605    KMQ91381.1    GGFJ01005926    MBW55067.1    GGFK01004515    MBW37836.1    AJWK01021981    AJWK01021982    AJWK01021983    KQ414665    KOC65132.1    GGFM01002227    MBW22978.1    GFDF01004250    JAV09834.1    GECU01004965    JAT02742.1    GGFJ01005927    MBW55068.1    GGFK01004005    MBW37326.1    GBRD01000693    GBRD01000692    GBRD01000691    GBRD01000690    JAG65130.1    BT127255    AEE62217.1    GGFM01002228    MBW22979.1    GFDF01004252    JAV09832.1    AXCN02000877    GGFM01006959    MBW27710.1    AXCM01001383    GFDG01002329    JAV16470.1    GFDF01004251    JAV09833.1    KA646311    AFP60940.1    GFDG01002328    JAV16471.1    GECZ01021944    JAS47825.1    DS235161    EEB12710.1    GAMD01002426    JAA99164.1    GDHF01004338    JAI47976.1    GDIQ01229903    JAK21822.1    GDIP01132057    GDIQ01082007    JAL71657.1    JAN12730.1    GDIP01122855    JAL80859.1    GDIQ01172873    JAK78852.1    GAMC01018560    JAB87995.1    GDIQ01097153    JAL54573.1    GDIQ01175274    JAK76451.1    GDIP01170451    GDIQ01172875    JAJ52951.1    JAK78850.1   

Proteomes

UP000005204    UP000053268    UP000283053    UP000218220    UP000007151    UP000053240    + More
UP000037510    UP000027135    UP000069940    UP000235965    UP000215335    UP000008820    UP000002358    UP000008237    UP000007266    UP000015103    UP000192223    UP000183832    UP000005203    UP000075903    UP000242457    UP000076407    UP000007062    UP000075902    UP000075840    UP000002320    UP000076502    UP000075900    UP000000673    UP000036403    UP000075885    UP000092461    UP000075881    UP000053825    UP000069272    UP000095301    UP000095300    UP000075886    UP000075884    UP000075883    UP000075920    UP000075880    UP000009046    UP000076408   

PRIDE

H9J3L5   

Pfam

PF00254   FKBP_C        + More
PF03704   BTAD
PF14291   DUF4371
PF13181   TPR_8
PF12569   NARP1
PF13176   TPR_7

Interpro

IPR011990   TPR-like_helical_dom_sf        + More
IPR019734   TPR_repeat       
IPR013026   TPR-contain_dom       
IPR005158   BTAD       
IPR001179   PPIase_FKBP_dom       
IPR025398   DUF4371       
IPR021183   NatA_aux_su       

SUPFAM

SSF48452   SSF48452       

Gene 3D

1.25.40.10    

ProteinModelPortal

H9J3L5   A0A194QCV5   A0A3S2LJ00   A0A2A4JBM8   A0A2A4JCM2   A0A2H1V5V9   + More
A0A212EW45   A0A1E1WQF4   A0A194R188   A0A0L7KZM2   A0A1B6CIU3   A0A067R311   A0A023EQ01   A0A2J7RJX8   U5EVG1   A0A224XIY8   A0A232FL82   A0A1S4FVM5   Q16MK5   A0A069DT63   A0A1S4FVT6   K7JJZ4   E2C4I6   Q16MK6   A0A0P4VRE9   A0A023F1H6   A0A1Y1KQQ1   A0A1Y1KRE4   D6WQV5   A0A2R7X2F8   T1HDK6   A0A0K8TPX4   A0A161ML76   A0A1W4WGY4   A0A1W4W6J4   A0A310SUB3   A0A1J1IEC5   A0A088A5M5   A0A1Q3F7K8   A0A1Q3F7L9   A0A1Q3F7H5   A0A182UVC9   A0A2A3E531   A0A182X4J8   Q7PI62   A0A182TWS1   A0A348G6B6   A0A182I4J5   B0WD01   A0A154PUR8   A0A182R965   A0A0A9YRZ0   W5J8E1   A0A0J7KMC0   A0A2M4BPR3   A0A2M4AAM2   A0A182PMV5   A0A1B0GJM0   A0A182JU29   A0A0L7R2M9   A0A2M3Z3F8   A0A182FGF4   A0A1L8DTW8   A0A1B6JU69   A0A2M4BQM1   A0A2M4A951   A0A0K8TJ23   A0A1I8MHG7   A0A1I8PY78   J3JVI7   A0A2M3Z374   A0A1L8DTN4   A0A182QGN6   A0A182NI90   A0A2M3ZGY7   A0A182LUU9   A0A1L8ECL2   A0A1L8DTP9   T1PC14   A0A182WBQ0   A0A182IXF5   A0A1L8ECM2   A0A1B6FC90   E0VH54   T1DHC7   A0A182Y2J2   A0A0K8W9Z2   A0A0P5HR46   A0A0P6DA46   A0A0N8CKH4   A0A0P5LA10   W8AHP7   A0A0P5RR79   A0A0P5LEB9   A0A0N8BJ23  

PDB

5MGX     E-value=1.02562e-25,     Score=290

KEGG

101736506    K09574 FK506-binding protein 8 [EC:5.2.1.8] | (RefSeq) peptidyl-prolyl cis-trans isomerase FKBP8-lik

GO

GO:0003755   GO:0016021   GO:0006457   GO:0005515   GO:0005524   GO:0000723   GO:0003684   GO:0005634   GO:0042162   GO:0043564   GO:0006418   GO:0003824  

Length:

407

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.50186

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03026

outside

1  -  379

TMhelix

380  -  402

inside

403  -  407

 

 

Pi

193.988762

Theta

181.987969

Tajima's D

-0.367022

CLR

2.141654

CSRT

0.272386380680966

Interpretation

Uncertain