Gene

KWMTBOMO11585

Pre Gene Modal

BGIBMGA004097

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_probable_cytochrome_P450_49a1_[Bombyx_mori]

Location

Bomo_Chr19(+):9291688-9295248      View in EpiBrowser

Full name

Probable cytochrome P450 49a1      

Alternative Name

CYPXLIXA1

Location in the cell

Mitochondrial   Reliability : 2.84

CDS

ATGGACAAAGCTCGGTGTTACACAGTCATGCCGGGACCAAGGCCCCTGCCTATTCTCGGCAACTCATGGAGGTTCGCATTAGGCTGGAAACCATGGAGAACGAAAAGGCTGGACTTGACGCTTTGGTGTTTACGATCGTTAGCCGGCGCGGGCGGTGCCGCTAAAGTGGCCAAACTATTCGGTCATCCCGATCTCGTTTTCCCTTTCTGCGCCGAAGAAACCGCGAGGATATACAGGAGGGAAGATGCGATGCCCCACAGAGCCGCAGCTCCATGTCTGAAGCACTACAAACAAGAGTTAAGGAAAGATTTCTTCGGAGACGAACCAGGACTTATTGGAATTCACGGAGAACCGTGGTCAAGATTTCGGTCAAAAGTATCCAAAGCATTAATAGCTCCCGAAGCGGCACGTGCTGCTGTACCGGAGTTAGATTACGTCGCTAATGACTTTGTTATAAGATTAGAACATCTCCTTGATCTGAACAGGGAACTTCCAAAAGATTTCCTCACGGAGCTCTATAAATGGGCTCTCGAATCTGTGGGCGCGTGGGCTTTGGGCACACGATTAGGATGTTTAAACGATACCAAAACGGACGCTAAGGAAATGATAAAATGTATACATGGATTTTTTCACAGTGTACCCGAATTGGAGTTGTCCGCACCGTTATGGAGAATATATTCAACGCCCGCTTACAAAACCTATATCGAAGCACTGGACTCTTTCAGATTACTCTGTTTAAAAAGATTAACTGATAAAGGAGTCTGTGCTCAGGTGGCTAAAAATTGCGGTCAGAAAGTAGCCACAATCCTGGCTTTAGATTTAATGTTAGTTGGGGTGGACACAACAGCCGCCGCAGCTGCGAGCTCTTTATACTTATTAGCTAATGTACCTAGGGCACAGAGAGCGCTTCAAAAAGAACTAGACACGAATTTACCGAAAAATAGGATATTGAATGATAAAGACTTGGACAAACTTCCTTATCTGAAAGCTTGTATAAAAGAAGCGTTGCGAATGAAACCGGTAATTTTGGGAAACGGACGATGCATTCAATCGGACACCACCATATCTGGCTACAAAGTTCCAAAAGGCCTCGGACGAGATATCGAGAACATGCGATCGTACAGTAGTGTCGGACGTTTGTCGCAAGCAGAAGGAAATAGGGATACACCCGTTCGCGTCACTCCCCTTTGGATTTGGTCGACGGATGTGCGTCGGGAAGAGATTCGCCGAAGTCGAATTGCAACTTTTACTGGCCAGGGTAATCATTGA

Protein

MDKARCYTVMPGPRPLPILGNSWRFALGWKPWRTKRLDLTLWCLRSLAGAGGAAKVAKLFGHPDLVFPFCAEETARIYRREDAMPHRAAAPCLKHYKQELRKDFFGDEPGLIGIHGEPWSRFRSKVSKALIAPEAARAAVPELDYVANDFVIRLEHLLDLNRELPKDFLTELYKWALESVGAWALGTRLGCLNDTKTDAKEMIKCIHGFFHSVPELELSAPLWRIYSTPAYKTYIEALDSFRLLCLKRLTDKGVCAQVAKNCGQKVATILALDLMLVGVDTTAAAAASSLYLLANVPRAQRALQKELDTNLPKNRILNDKDLDKLPYLKACIKEALRMKPVILGNGRCIQSDTTISGYKVPKGLGRDIENMRSYSSVGRLSQAEGNRDTPVRVTPLWIWSTDVRREEIRRSRIATFTGQGNH

Description

May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Keywords

Alternative splicing   Complete proteome   Endoplasmic reticulum   Heme   Iron   Membrane   Metal-binding   Microsome   Monooxygenase   Oxidoreductase   Reference proteome  

Feature

chain  Probable cytochrome P450 49a1
splice variant  In isoform C.

Uniprot

H9J3L0   A0A194QD08   A0A194QVQ2   A0A212EW64   A0A0L7LS76   A0A1B0G778   + More
A0A1A9VGK8   A0A1A9X3H5   B3N6D8   B4KN43   A0A125S6N7   A0A0L0BP26   B4GG60   Q28XI1   B4HMQ3   A0A0B4K7M1   Q9V5L3   A0A3B0JFL4   A0A3B0JN88   B4NXN7   A0A0R1DMZ7   B4QIE0   B4N662   A0A068FC46   A0A1W4VCA1   A0A0M4ETM1   B4J7I9   B4LKE7   A0A0A1WFU7   W8BEW4   W8B9Y6   A0A0K8U800   A0A1I8MIW9   A0A1I8MIX8   A0A1I8QAX8   B3MI40   A0A182HWH4   A0A182XML5   A0A182VDU1   A0A182UA43   A0A182L361   Q7PNM9   A0A067R674   A0A1J1J2W8   A0A336JXF2   A0A182PLU9   A0A182FHV4   B0VZB4   A0A182Y248   A0A182QKV0   A0A1Q3FMD9   A0A182J2S6   A0A2M4BKS7   A0A2J7PDU4   W5J440   A0A182S4M1   Q16Y74   E0VDR0   D6WQ58   A0A0M4HGU6   J9JRR2   A0A1B6CMB7   A0A2D1GSD3   A0A2H8TLX1   A0A0K0LB65   A0A2S2QSX9   A0A1V0D9E8   A0A182JZ57   A0A067RSD6   I1VJ31   A0A182NJR1   A0A182SPT5   A0A182WKZ1   A0A248QEZ9   A0A194Q424   A0A0M9A7Y8   A0A3S2NTQ9   E2AFK1   A0A154PR32   A0A2A3EML1   A0A2W1C0B2   A0A026WVH3   A0A212FL05   A0A2J7PYK4   A0A088A457   A0A0M4H594   K7J2R1   A0A232F204   A0A0L7R6B8   A0A2J7PYM6   A0A2J7PYJ4   A0A2A4K848   D2A103   E0W2B1   A0A1J1J892   A0A023F3W6   A0A1W6L1F3  

EC Number

1.14.-.-

Pubmed

19121390    26354079    22118469    26227816    17994087    18057021    + More
26108605    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    17550304    22936249    25880816    25830018    24495485    25315136    20966253    12364791    14747013    17210077    24845553    25244985    20920257    23761445    17510324    20566863    18362917    19820115    26319543    22516182    28881445    20798317    28756777    24508170    30249741    20075255    28648823    25474469   

EMBL

BABH01021564    BABH01021565    KQ459185    KPJ03304.1    KQ461073    KPJ09613.1    + More
AGBW02012080    OWR45707.1    JTDY01000218    KOB78234.1    CCAG010008069    CH954177    EDV58107.1    KQS70245.1    CH933808    EDW08870.1    KRG04326.1    KRG04327.1    KT601129    AME15798.1    JRES01001578    KNC21835.1    CH479183    EDW35480.1    CM000071    EAL26335.1    CH480816    EDW47265.1    AE013599    AFH08010.1    AY075453    AY102688    BT056244    OUUW01000001    SPP74110.1    SPP74111.1    CM000157    EDW89662.1    KRJ98649.1    KRJ98650.1    CM000362    CM002911    EDX06500.1    KMY92793.1    CH964154    EDW79851.2    KJ702277    AID61431.1    CP012524    ALC40607.1    CH916367    EDW01113.1    CH940648    EDW61738.1    GBXI01016535    JAC97756.1    GAMC01011087    JAB95468.1    GAMC01011083    JAB95472.1    GDHF01029542    JAI22772.1    CH902619    EDV38050.1    KPU77234.1    APCN01001491    AAAB01008960    EAA11902.5    KK852927    KDR13690.1    CVRI01000067    CRL06719.1    UFQS01000004    UFQT01000004    SSW96881.1    SSX17268.1    DS231813    EDS25689.1    AXCN02000515    AXCN02000516    GFDL01006328    JAV28717.1    GGFJ01004535    MBW53676.1    NEVH01026142    PNF14497.1    ADMH02002165    ETN58108.1    CH477523    EAT39564.1    DS235083    EEB11516.1    KQ971354    EFA07521.1    KR012817    ALD15892.1    ABLF02025275    ABLF02025279    ABLF02046672    GEDC01022689    JAS14609.1    MF471397    ATN96003.1    GFXV01002483    MBW14288.1    KM216993    AIW79956.1    GGMS01011631    MBY80834.1    KY212061    ARA91625.1    KK852446    KDR23725.1    JQ855652    AFI45015.1    KX443475    ASO98050.1    KQ459585    KPI98160.1    KQ435728    KOX77763.1    RSAL01000206    RVE44347.1    GL439118    EFN67752.1    KQ435066    KZC14341.1    KZ288219    PBC32281.1    KZ149927    PZC77503.1    KK107085    QOIP01000008    EZA60040.1    RLU19440.1    AGBW02007925    OWR54417.1    NEVH01020348    PNF21416.1    KR012815    ALD15890.1    NNAY01001258    OXU24592.1    KQ414648    KOC66321.1    PNF21412.1    PNF21417.1    NWSH01000071    PCG79963.1    KQ971338    EFA02807.1    DS235875    EEB19767.1    CVRI01000075    CRL08607.1    GBBI01002577    JAC16135.1    KX609544    ARN17951.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000037510    UP000092444    + More
UP000078200    UP000091820    UP000008711    UP000009192    UP000037069    UP000008744    UP000001819    UP000001292    UP000000803    UP000268350    UP000002282    UP000000304    UP000007798    UP000192221    UP000092553    UP000001070    UP000008792    UP000095301    UP000095300    UP000007801    UP000075840    UP000076407    UP000075903    UP000075902    UP000075882    UP000007062    UP000027135    UP000183832    UP000075885    UP000069272    UP000002320    UP000076408    UP000075886    UP000075880    UP000235965    UP000000673    UP000075900    UP000008820    UP000009046    UP000007266    UP000007819    UP000075881    UP000075884    UP000075901    UP000075920    UP000053105    UP000283053    UP000000311    UP000076502    UP000242457    UP000053097    UP000279307    UP000005203    UP000002358    UP000215335    UP000053825    UP000218220   

PRIDE

H9J3L0    Q9V5L3   

Pfam

PF00067   p450

Interpro

IPR036396   Cyt_P450_sf        + More
IPR002401   Cyt_P450_E_grp-I       
IPR001128   Cyt_P450       
IPR017972   Cyt_P450_CS       
IPR002403   Cyt_P450_E_grp-IV       
IPR000253   FHA_dom       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

H9J3L0   A0A194QD08   A0A194QVQ2   A0A212EW64   A0A0L7LS76   A0A1B0G778   + More
A0A1A9VGK8   A0A1A9X3H5   B3N6D8   B4KN43   A0A125S6N7   A0A0L0BP26   B4GG60   Q28XI1   B4HMQ3   A0A0B4K7M1   Q9V5L3   A0A3B0JFL4   A0A3B0JN88   B4NXN7   A0A0R1DMZ7   B4QIE0   B4N662   A0A068FC46   A0A1W4VCA1   A0A0M4ETM1   B4J7I9   B4LKE7   A0A0A1WFU7   W8BEW4   W8B9Y6   A0A0K8U800   A0A1I8MIW9   A0A1I8MIX8   A0A1I8QAX8   B3MI40   A0A182HWH4   A0A182XML5   A0A182VDU1   A0A182UA43   A0A182L361   Q7PNM9   A0A067R674   A0A1J1J2W8   A0A336JXF2   A0A182PLU9   A0A182FHV4   B0VZB4   A0A182Y248   A0A182QKV0   A0A1Q3FMD9   A0A182J2S6   A0A2M4BKS7   A0A2J7PDU4   W5J440   A0A182S4M1   Q16Y74   E0VDR0   D6WQ58   A0A0M4HGU6   J9JRR2   A0A1B6CMB7   A0A2D1GSD3   A0A2H8TLX1   A0A0K0LB65   A0A2S2QSX9   A0A1V0D9E8   A0A182JZ57   A0A067RSD6   I1VJ31   A0A182NJR1   A0A182SPT5   A0A182WKZ1   A0A248QEZ9   A0A194Q424   A0A0M9A7Y8   A0A3S2NTQ9   E2AFK1   A0A154PR32   A0A2A3EML1   A0A2W1C0B2   A0A026WVH3   A0A212FL05   A0A2J7PYK4   A0A088A457   A0A0M4H594   K7J2R1   A0A232F204   A0A0L7R6B8   A0A2J7PYM6   A0A2J7PYJ4   A0A2A4K848   D2A103   E0W2B1   A0A1J1J892   A0A023F3W6   A0A1W6L1F3  

PDB

3K9Y     E-value=2.42355e-21,     Score=252

KEGG

105842283    K17960 cytochrome P450 family 49 subfamily A | (RefSeq) probable cytochrome P450 49a1

GO

GO:0005506   GO:0016705   GO:0020037   GO:0004497   GO:0005789   GO:0008386   GO:0046872   GO:0007186   GO:0019001   GO:0031683   GO:0005525   GO:0007188   GO:0006418   GO:0003824   GO:0055114  

Subcellular location

Endoplasmic reticulum membrane  
Microsome membrane  

Length:

422

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.23122

Exp number, first 60 AAs:

0.26463

Total prob of N-in:

0.08904

outside

1  -  422

 

 

Pi

204.534955

Theta

149.728948

Tajima's D

0.388539

CLR

0.000732

CSRT

0.47847607619619

Interpretation

Uncertain