Gene

KWMTBOMO11584  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004022

Annotation

Guanine_nucleotide-binding_protein_G(o)_subunit_alpha_47A_[Papilio_xuthus]

Location

Bomo_Chr19(-):9276824-9279957      View in EpiBrowser

Full name

G protein alpha o subunit       + More
Guanine nucleotide-binding protein G(o) subunit alpha      

Alternative Name

Guanine nucleotide-binding protein G(o) subunit alpha 47A

Location in the cell

Nuclear   Reliability : 1.947

CDS

ATGCTCACGGTCTCCTTTGATTCTAGTTTCCTGGACGACCTCGACCGGTTAGGAGCAAAGGATTACCAGCCCACCGAACAAGATATCCTAAGGACTAGAGTCAAAACGACTGGAATCGTCGAAGTACATTTCTCCTTCAAAAACCTCAATTTCAAATTGTTCGACGTGGGCGGGCAGCGATCGGAGAGGAAGAAATGGATTCATTGCTTCGAGGACGTGACCGCGATCATATTCTGTGTTGCCATGTCTGAATATGATCAGGTGTTGCACGAGGATGAAACAACGAACCGTATGCAGGAGAGTCTAAAGTTGTTCGATTCTATCTGCAACAACAAATGGTTCACCGACACCAGCATCATCTTGTTCCTGAACAAGAAGGATCTCTTCGAGGAAAAAATTCGCAGATCGCCGCTCACCATATGCTTTCCAGAATATACAGGCGCGCAAGAGTACGGCGAGGCGGCCGCGTACATCCAGGCGCAGTTCGAAGCGAAGAACAAGTCCACCACGAAGGAGATCTACTGCCACATGACGTGCGCCACCGACACGAACAACATCCAGTTTGTGTTCGACGCGGTGACCGACGTGATCATCGCCAACAACCTGCGCGGCTGCGGCCTGTACTAG

Protein

MLTVSFDSSFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRRSPLTICFPEYTGAQEYGEAAAYIQAQFEAKNKSTTKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGLY

Description

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Plays a role in glial cell differentiation during embryogenesis; loco, Galphai and the G-protein coupled receptor, moody, are required in the surface glia to achieve effective insulation of the nerve cord.

Subunit

G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.

Similarity

Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Keywords

Alternative splicing   Complete proteome   GTP-binding   Lipoprotein   Magnesium   Metal-binding   Myristate   Nucleotide-binding   Palmitate   Reference proteome   Transducer  

Feature

chain  G protein alpha o subunit
splice variant  In isoform B.

Uniprot

H9J3D5   D2XZ04   Q5R250   A0A194QED1   A0A2H1WB78   A0A182JJ92   + More
A0A194QWD4   D2XZ05   A0A1A9ZGA6   A0A336LLN3   A0A2A4JG95   A0A212EW37   A0A1E1W4B8   A0A182Y247   A0A182PLV0   A0A182XML6   A0A182V4E5   A0A182KAY7   A0A182L367   A0A182SF16   A0A182M5P0   A0A182WKZ0   A0A1L8DL24   A0A182FHV5   B4J7I8   Q28XI2   B4GG59   P16378-2   B4QID9   B3N6D7   B4NXN6   A0A0R1DMR4   A0A0Q5W9C7   A0A0J9R9S9   P16378   B3MI39   B4N661   A0A1W4VQM8   A0A3B0JSM1   A0A0R3NPG2   A0A0Q9WFL7   A0A0Q9X8E5   A0A0M5J9N2   A0A1B6KYF7   A0A1B6GKT7   A0A3B0JKW1   B4HMQ2   A0A1W4VQ13   A0A0Q9X0Z5   A0A0P8XRN2   A0A182QZE3   W5J1M2   B4KN42   B4LKE6   D3TR64   A0A1B0C7Y1   A0A1I8NGC7   A0A1I8NT78   A0A084WJP6   A0A1I8NGD7   A0A1I8NT71   E9H7Z0   A0A1B0G777   P38404   A0A023FAP1   B0VZB3   A0A0A9WN03   Q7Q6L8   A0A2M4CKF9   A0A2M4AJ07   A0A2M4BT69   A0A336LHE6   A0A2M4AHR7   A0A1Q3G4I3   A0A2J7Q6S9   Q16Y75   A0A182S4M0   A0A3F2YSM3   A0A2M4BSA5   A0A1W7R6W8   A0A2M4CK32   A0NEH6   A0A1B6E6E0   A0A1J1J2Q1   A0A1Q3FUH2   A0A3Q0IP61   Q6J2K4   J9K924   A0A067R1D8   A0A2S2Q8T0   T1HPD2   E2BQ26   E0VQK9   A0A2M4CVT1   F2VP16   W8C0A1   W8BK17   A0A162SZC2   A0A1Q3FUA8   A0A0F7VKH2  

Pubmed

19121390    15776452    26354079    22118469    25244985    20966253    + More
17994087    15632085    2519611    2509462    2509463    2509464    10731132    12537572    12537569    10079238    22936249    18057021    17550304    20920257    23761445    20353571    25315136    24438588    21292972    2119206    25474469    25401762    26823975    12364791    14747013    17210077    17510324    24845553    20798317    20566863    21125564    24495485   

EMBL

BABH01021563    BABH01021564    GU266213    ADB25316.1    AB167957    BAD74000.1    + More
KQ459185    KPJ03305.1    ODYU01007387    SOQ50102.1    KQ461073    KPJ09614.1    GU266214    ADB25317.1    UFQT01000004    SSX17267.1    NWSH01001566    PCG70839.1    AGBW02012080    OWR45706.1    GDQN01009250    JAT81804.1    AXCM01003669    GFDF01007019    JAV07065.1    CH916367    EDW01112.1    CM000071    EAL26334.1    CH479183    EDW35479.1    M86660    M29602    M31203    M29601    M31198    M31199    M31200    M31201    M31202    M30151    M30152    M31129    M29731    M29732    AE013599    AY121631    BT001768    BT046134    CM000362    CM002911    EDX06499.1    KMY92789.1    CH954177    EDV58106.1    KQS70246.1    CM000157    EDW89661.1    KRJ98648.1    KRJ98647.1    KQS70247.1    KMY92790.1    KMY92792.1    CH902619    EDV38049.1    CH964154    EDW79850.1    OUUW01000001    SPP74108.1    KRT03006.1    CH940648    KRF80196.1    CH933808    KRG04325.1    CP012524    ALC40606.1    GEBQ01023498    JAT16479.1    GECZ01028525    GECZ01006856    JAS41244.1    JAS62913.1    SPP74109.1    CH480816    EDW47264.1    KRF99171.1    KPU77232.1    KPU77233.1    AXCN02000516    ADMH02002165    ETN58107.1    EDW08869.1    EDW61737.1    KRF80195.1    KRF80197.1    EZ423916    ADD20192.1    JXJN01024932    JXJN01024933    JXJN01024934    JXJN01024935    JXJN01024936    ATLV01024045    ATLV01024046    KE525348    KFB50440.1    GL732602    EFX72162.1    CCAG010008069    GBBI01000170    JAC18542.1    DS231813    EDS25690.1    KM610204    GBHO01035721    GDHC01014612    AJQ81035.1    JAG07883.1    JAQ04017.1    AAAB01008960    EAA11901.3    GGFL01001483    MBW65661.1    GGFK01007401    MBW40722.1    GGFJ01006827    MBW55968.1    SSX17266.1    GGFK01007015    MBW40336.1    GFDL01000334    JAV34711.1    NEVH01017452    PNF24294.1    CH477523    EAT39565.1    APCN01001491    GGFJ01006826    MBW55967.1    GEHC01000747    JAV46898.1    GGFL01001485    MBW65663.1    EAU76497.2    GEDC01003807    GEDC01001973    JAS33491.1    JAS35325.1    CVRI01000067    CRL06717.1    GFDL01003857    JAV31188.1    AY603976    AAT34978.1    ABLF02021378    ABLF02021382    ABLF02021383    ABLF02021386    ABLF02021387    KK852779    KDR16702.1    GGMS01004936    MBY74139.1    ACPB03023209    ACPB03023210    ACPB03023211    GL449694    EFN82214.1    DS235430    EEB15665.1    GGFL01005252    MBW69430.1    GU564592    ADK94869.1    GAMC01007499    JAB99056.1    GAMC01007498    GAMC01007497    JAB99057.1    LRGB01000024    KZS21762.1    GFDL01003861    JAV31184.1    LN830713    CFW94222.1   

Proteomes

UP000005204    UP000053268    UP000075880    UP000053240    UP000092445    UP000218220    + More
UP000007151    UP000076408    UP000075885    UP000076407    UP000075903    UP000075881    UP000075882    UP000075901    UP000075883    UP000075920    UP000069272    UP000001070    UP000001819    UP000008744    UP000000803    UP000000304    UP000008711    UP000002282    UP000007801    UP000007798    UP000192221    UP000268350    UP000008792    UP000009192    UP000092553    UP000001292    UP000075886    UP000000673    UP000092460    UP000095301    UP000095300    UP000030765    UP000000305    UP000092444    UP000002320    UP000007062    UP000235965    UP000008820    UP000075900    UP000075840    UP000183832    UP000079169    UP000007819    UP000027135    UP000015103    UP000008237    UP000009046    UP000076858   

PRIDE

H9J3D5    D2XZ04    Q5R250    D2XZ05    P16378    P38404    + More

Pfam

PF00503   G-alpha

Interpro

IPR001408   Gprotein_alpha_I        + More
IPR001019   Gprotein_alpha_su       
IPR027417   P-loop_NTPase       
IPR011025   GproteinA_insert       

SUPFAM

SSF47895   SSF47895        + More
SSF52540   SSF52540       

Gene 3D

1.10.400.10    

CDD

cd00066  G-alpha

ProteinModelPortal

H9J3D5   D2XZ04   Q5R250   A0A194QED1   A0A2H1WB78   A0A182JJ92   + More
A0A194QWD4   D2XZ05   A0A1A9ZGA6   A0A336LLN3   A0A2A4JG95   A0A212EW37   A0A1E1W4B8   A0A182Y247   A0A182PLV0   A0A182XML6   A0A182V4E5   A0A182KAY7   A0A182L367   A0A182SF16   A0A182M5P0   A0A182WKZ0   A0A1L8DL24   A0A182FHV5   B4J7I8   Q28XI2   B4GG59   P16378-2   B4QID9   B3N6D7   B4NXN6   A0A0R1DMR4   A0A0Q5W9C7   A0A0J9R9S9   P16378   B3MI39   B4N661   A0A1W4VQM8   A0A3B0JSM1   A0A0R3NPG2   A0A0Q9WFL7   A0A0Q9X8E5   A0A0M5J9N2   A0A1B6KYF7   A0A1B6GKT7   A0A3B0JKW1   B4HMQ2   A0A1W4VQ13   A0A0Q9X0Z5   A0A0P8XRN2   A0A182QZE3   W5J1M2   B4KN42   B4LKE6   D3TR64   A0A1B0C7Y1   A0A1I8NGC7   A0A1I8NT78   A0A084WJP6   A0A1I8NGD7   A0A1I8NT71   E9H7Z0   A0A1B0G777   P38404   A0A023FAP1   B0VZB3   A0A0A9WN03   Q7Q6L8   A0A2M4CKF9   A0A2M4AJ07   A0A2M4BT69   A0A336LHE6   A0A2M4AHR7   A0A1Q3G4I3   A0A2J7Q6S9   Q16Y75   A0A182S4M0   A0A3F2YSM3   A0A2M4BSA5   A0A1W7R6W8   A0A2M4CK32   A0NEH6   A0A1B6E6E0   A0A1J1J2Q1   A0A1Q3FUH2   A0A3Q0IP61   Q6J2K4   J9K924   A0A067R1D8   A0A2S2Q8T0   T1HPD2   E2BQ26   E0VQK9   A0A2M4CVT1   F2VP16   W8C0A1   W8BK17   A0A162SZC2   A0A1Q3FUA8   A0A0F7VKH2  

PDB

6OIK     E-value=6.11281e-98,     Score=909

KEGG

692460    K04534 guanine nucleotide-binding protein G(o) subunit alpha | (RefSeq) Go, GaO1, GaO2; G protein al

GO

GO:0003924   GO:0046872   GO:0031683   GO:0007188   GO:0005525   GO:0007419   GO:0060857   GO:0001737   GO:0061343   GO:0019722   GO:0019991   GO:0035567   GO:0032291   GO:0030866   GO:0005834   GO:0050916   GO:0045886   GO:0008356   GO:0042595   GO:0007507   GO:0005886   GO:0007186   GO:0001664   GO:0007165   GO:0004871   GO:0019001   GO:0006418   GO:0003824  

PANTHER

PTHR10218  

Length:

208

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0058

Exp number, first 60 AAs:

0.00032

Total prob of N-in:

0.01816

outside

1  -  208

 

 

Pi

212.867573

Theta

166.243966

Tajima's D

0.86364

CLR

0.144636

CSRT

0.625018749062547

Interpretation

Uncertain