Gene

KWMTBOMO11567

Pre Gene Modal

BGIBMGA004088

Annotation

SRC_protein_[Operophtera_brumata]

Location

Bomo_Chr19(+):8570088-8570647      View in EpiBrowser

Full name

Tyrosine-protein kinase      

Location in the cell

Nuclear   Reliability : 3.393

CDS

ATGGGGAATTGCTTTAGTAGCACAGGAGAAAAGGATTCAAAAAACAAAAATGAGAGGCCTAATCCTCACGAGGAAGACCCTAGACAATTTCAGAGCCCCGTGCCTACCCCGCCTCCAGATCCGATAAGATCTACGGTAAATCAGGGTACAGATACTAGTGAGGTCCCTCCCACTCGAATATTTGTAGCGCTGTATGATTACGATGCCAGGACCGATGAAGACCTGAGTTTTAGAAAGGGAGAGCATTTGGAAATTCTTAATGATACACAAGGTGACTGGTGGCTTGCTAGAAGTAAGAAAACCAAACAAGAGGGCTACATTCCTTCAAACTATGTGGCGCGCCTGCAGTCAATAGAGGCCGAACCGTGA

Protein

MGNCFSSTGEKDSKNKNERPNPHEEDPRQFQSPVPTPPPDPIRSTVNQGTDTSEVPPTRIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKKTKQEGYIPSNYVARLQSIEAEP

Catalytic Activity

ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]

Similarity

Belongs to the protein kinase superfamily. Tyr protein kinase family.

Uniprot

H9J3K1   A0A2W1C1E4   A0A0L7LS73   H6WWN8   A0A2A4JF86   A0A212EX39   + More
A0A194QVY1   A0A194QCY5   A0A182VAC9   A0A182Q637   Q7PPB4   V5GWD0   A0A1Q3FWY6   A0A1Y1K4G5   A0A2M3Z5R1   A0A0T6B508   A0A1B0CTS0   A0A2M4CTE6   A0A023EUG9   A0A2M4AF99   A0A1B0DNY9   A0A139WE74   A0A0P6K148   A0A232FAQ7   A0A0L7QY19   W8AI25   A0A1I8QCH4   A0A2H8TP58   A0A154P907   A0A1B0FIZ2   A0A1A9XDG3   A0A1A9UK15   A0A1B0AMM6   N6TZH6   A0A1L8DKT6   A0A026WWJ6   A0A3L8D9C6   A0A2A3E5Z4   A0A087ZQN7   A0A1B0AFV5   A0A336MWQ7   A0A2R7X2T8   K7IZF9   A0A2S2NXJ7   A0A0M9A803   U5EXY3   A0A0A1WUV7   A0A0K8V7S5   A0A034VYI5   E9GIM4   A0A2S2Q4N3   A0A2H8TL13   A0A222NUJ6   A0A293N310   A0A0C9QI03   A0A2R5L4C4   A0A067R369   A0A1B6JMZ7   J9JNB6   A0A2S2NB65   A0A0P4VU94   A0A1A9WYV5   A0A1I8M3N0   T1P9H0   A0A0P4VY18   A0A0Q9X743   B4MDY3   B4KSC5   A0A0Q9WCV1   A0A0Q9X742   A0A069DVD5   B4MPR7   B4J9U9   A0A0P5A5F1   A0A0P4XQK9   A0A0P5YDS6   E2B7Q6   B5DZR9   B4GJ00   A0A3B0J3D5   A0A087TN49   A0A0P6H5F8   A0A0N8CN19   A0A0P6CS57   A0A2J7QER5   A0A0P5YQJ9   A0A0P5RUK3   A0A0P5DRN0   A0A0P5WKN5   A0A0P5Z8A8   A0A0P6HUT8   A0A0J7L5D3   E2AZR3   A0A0K8SRE8   A0A0A9WK16   A0A195FER6   A0A195AWS6  

EC Number

2.7.10.2

Pubmed

19121390    28756777    26227816    22118469    26354079    12364791    + More
14747013    17210077    28004739    24945155    18362917    19820115    26999592    28648823    24495485    23537049    24508170    30249741    20075255    25830018    25348373    21292972    28743627    24845553    27129103    25315136    17994087    26334808    20798317    15632085    25401762    26823975   

EMBL

BABH01021500    KZ149917    PZC77923.1    JTDY01000252    KOB78051.1    JQ326307    + More
AFA35123.1    NWSH01001807    PCG70062.1    AGBW02011827    OWR46066.1    KQ461073    KPJ09632.1    KQ459185    KPJ03327.1    AXCN02000452    AAAB01008960    EAA10750.4    GALX01002469    JAB65997.1    GFDL01002958    JAV32087.1    GEZM01098760    JAV53767.1    GGFM01003101    MBW23852.1    LJIG01009807    KRT82342.1    AJWK01027922    GGFL01004357    MBW68535.1    GAPW01001001    JAC12597.1    GGFK01006134    MBW39455.1    AJVK01007853    AJVK01007854    KQ971354    KYB26278.1    GDUN01000124    JAN95795.1    NNAY01000510    OXU27926.1    KQ414699    KOC63451.1    GAMC01021212    GAMC01021210    GAMC01021208    GAMC01021205    JAB85347.1    GFXV01004130    MBW15935.1    KQ434846    KZC08321.1    CCAG010002049    JXJN01000497    APGK01045644    KB741037    KB632319    ENN74685.1    ERL92275.1    GFDF01007005    JAV07079.1    KK107078    EZA60450.1    QOIP01000011    RLU17130.1    KZ288386    PBC26481.1    UFQS01001398    UFQT01000246    UFQT01001398    SSX10696.1    SSX22342.1    SSX30378.1    KK856617    PTY26103.1    GGMR01009324    MBY21943.1    KQ435724    KOX78346.1    GANO01000680    JAB59191.1    GBXI01012012    GBXI01011347    JAD02280.1    JAD02945.1    GDHF01017536    GDHF01011814    GDHF01005637    GDHF01001804    JAI34778.1    JAI40500.1    JAI46677.1    JAI50510.1    GAKP01010583    GAKP01010582    GAKP01010581    JAC48371.1    GL732546    EFX80725.1    GGMS01003483    MBY72686.1    GFXV01003018    MBW14823.1    KX940981    QCYY01001000    ASQ43185.1    ROT81245.1    GFWV01021282    MAA46010.1    GBYB01014308    JAG84075.1    GGLE01000213    MBY04339.1    KK853035    KDR12232.1    GECU01007254    JAT00453.1    ABLF02040581    ABLF02040584    GGMR01001738    MBY14357.1    GDKW01000351    JAI56244.1    KA645354    AFP59983.1    GDRN01104602    JAI57883.1    CH933808    KRG04111.1    CH940662    EDW58748.1    EDW08407.1    KRF78453.1    KRG04112.1    GBGD01001113    JAC87776.1    CH963849    EDW74106.1    CH916367    EDW01513.1    GDIP01216188    JAJ07214.1    GDIP01239491    JAI83910.1    GDIP01059158    JAM44557.1    GL446201    EFN88269.1    CM000071    EDY69222.1    CH479183    EDW36418.1    OUUW01000001    SPP75835.1    KK115982    KFM66538.1    GDIQ01034216    LRGB01000568    JAN60521.1    KZS18096.1    GDIP01115695    JAL88019.1    GDIQ01088093    JAN06644.1    NEVH01015306    PNF27080.1    GDIP01056200    JAM47515.1    GDIQ01101351    JAL50375.1    GDIP01151632    JAJ71770.1    GDIP01097755    JAM05960.1    GDIP01047694    JAM56021.1    GDIQ01014619    JAN80118.1    LBMM01000686    KMQ97758.1    GL444277    EFN61042.1    GBRD01010115    JAG55709.1    GBHO01038409    GBHO01002889    GDHC01010424    GDHC01008975    JAG05195.1    JAG40715.1    JAQ08205.1    JAQ09654.1    KQ981636    KYN38861.1    KQ976725    KYM76621.1   

Proteomes

UP000005204    UP000037510    UP000218220    UP000007151    UP000053240    UP000053268    + More
UP000075903    UP000075886    UP000007062    UP000092461    UP000092462    UP000007266    UP000215335    UP000053825    UP000095300    UP000076502    UP000092444    UP000092443    UP000078200    UP000092460    UP000019118    UP000030742    UP000053097    UP000279307    UP000242457    UP000005203    UP000092445    UP000002358    UP000053105    UP000000305    UP000283509    UP000027135    UP000007819    UP000091820    UP000095301    UP000009192    UP000008792    UP000007798    UP000001070    UP000008237    UP000001819    UP000008744    UP000268350    UP000054359    UP000076858    UP000235965    UP000036403    UP000000311    UP000078541    UP000078540   

PRIDE

H9J3K1    H6WWN8   

Pfam

PF00018   SH3_1        + More
PF00017   SH2
PF07714   Pkinase_Tyr

Interpro

IPR001452   SH3_domain        + More
IPR036028   SH3-like_dom_sf       
IPR020635   Tyr_kinase_cat_dom       
IPR000719   Prot_kinase_dom       
IPR011009   Kinase-like_dom_sf       
IPR008266   Tyr_kinase_AS       
IPR036860   SH2_dom_sf       
IPR000980   SH2       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR017441   Protein_kinase_ATP_BS       

SUPFAM

SSF50044   SSF50044        + More
SSF55550   SSF55550       
SSF56112   SSF56112       

Gene 3D

3.30.505.10    

ProteinModelPortal

H9J3K1   A0A2W1C1E4   A0A0L7LS73   H6WWN8   A0A2A4JF86   A0A212EX39   + More
A0A194QVY1   A0A194QCY5   A0A182VAC9   A0A182Q637   Q7PPB4   V5GWD0   A0A1Q3FWY6   A0A1Y1K4G5   A0A2M3Z5R1   A0A0T6B508   A0A1B0CTS0   A0A2M4CTE6   A0A023EUG9   A0A2M4AF99   A0A1B0DNY9   A0A139WE74   A0A0P6K148   A0A232FAQ7   A0A0L7QY19   W8AI25   A0A1I8QCH4   A0A2H8TP58   A0A154P907   A0A1B0FIZ2   A0A1A9XDG3   A0A1A9UK15   A0A1B0AMM6   N6TZH6   A0A1L8DKT6   A0A026WWJ6   A0A3L8D9C6   A0A2A3E5Z4   A0A087ZQN7   A0A1B0AFV5   A0A336MWQ7   A0A2R7X2T8   K7IZF9   A0A2S2NXJ7   A0A0M9A803   U5EXY3   A0A0A1WUV7   A0A0K8V7S5   A0A034VYI5   E9GIM4   A0A2S2Q4N3   A0A2H8TL13   A0A222NUJ6   A0A293N310   A0A0C9QI03   A0A2R5L4C4   A0A067R369   A0A1B6JMZ7   J9JNB6   A0A2S2NB65   A0A0P4VU94   A0A1A9WYV5   A0A1I8M3N0   T1P9H0   A0A0P4VY18   A0A0Q9X743   B4MDY3   B4KSC5   A0A0Q9WCV1   A0A0Q9X742   A0A069DVD5   B4MPR7   B4J9U9   A0A0P5A5F1   A0A0P4XQK9   A0A0P5YDS6   E2B7Q6   B5DZR9   B4GJ00   A0A3B0J3D5   A0A087TN49   A0A0P6H5F8   A0A0N8CN19   A0A0P6CS57   A0A2J7QER5   A0A0P5YQJ9   A0A0P5RUK3   A0A0P5DRN0   A0A0P5WKN5   A0A0P5Z8A8   A0A0P6HUT8   A0A0J7L5D3   E2AZR3   A0A0K8SRE8   A0A0A9WK16   A0A195FER6   A0A195AWS6  

PDB

3UF4     E-value=4.54313e-19,     Score=225

KEGG

100862655    K08892 fyn-related kinase [EC:2.7.10.2] | (RefSeq) SRC; tyrosine-protein kinase Src42A-like

GO

GO:0005524   GO:0004715   GO:0016301   GO:0007169   GO:0038083   GO:0005102   GO:0030154   GO:0031234   GO:0005515   GO:0008528   GO:0016021   GO:0004713   GO:0004888   GO:0007166   GO:0003707   GO:0006418   GO:0003824  

Length:

122

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.11522

outside

1  -  122

 

 

Pi

256.729783

Theta

240.523461

Tajima's D

0.212229

CLR

0

CSRT

0.426228688565572

Interpretation

Uncertain