SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO11561
Pre Gene Modal
BGIBMGA004082
Annotation
PREDICTED:_tyrosine-protein_kinase_hopscotch_[Papilio_xuthus]
Full name
Tyrosine-protein kinase       + More
Non-specific protein-tyrosine kinase      
Location in the cell
Nuclear   Reliability : 2.473
 

Sequence

CDS
ATGGCAACAGTGGAAGATATAGTTAAAGTGGCCGTGGTGACCAATCGTACACCAAATAATGTAAGGTGTACTAGCACACTTACTGCAGAAGAATTGTGTATAATATTGTGTAAGAAATACAACATACCTCCTCTAACTCGTACATTATTTGCATTACGAGTTAAGGGTACTGATTATTTCCTCAAGGATAACTGTAAGGTCCTCTCGGGCTCTAGGGACTATGAACTGAGGATTCGTTTCAAGGTGCCAAGGTTAAGTCTTCTTATAACATTGGATGAGACCACATATGATTATTATTTCCAACAAGCAAGGAATGACGTCAATGAAAATAAAATACCTGAGATTAAGTATCCTGAACATAAGCAAGAATTACTCGGACTGGGGATCACAGATATGACCCGTGCAATAGCTGAAGAGAGATTACCACTGAATGATGTTATTCGAAATTACAAAAAATATATTCCTAAAGAGATTGCTAAAAGACATGGACCATTTCCTAAAAAGTATGCCATTGATTATCTACCGCAATTGTCTTCGGTCGGTCATAATGTGAATTACGTGAAGAATTTGTACTTACAACAGTTATACGCGTTAGCACCAAATTACCTCGCTGAGGAGTACGATAATGTTCTGTGGCAAAACGGCAGTGAGATGACGCCAGTGCGGGTGATGGTGGCACCTTTTCATCCGCACCATCCTGGAATACGACTTTACAACACTCTGAAACGTGAATGGTTCCATGTGTGCTCCGTCGAGGAGTTGATATATCTGACAAGGAACGGTGATAGTTCAGTGGAAGTGTCAAGAAGAGGCACTCCTGTGTTTCTCAAGTTCAAGTCCGAGGATCAGCTTTCGTCTTTTATTTCTGTCTGTGATGGATATTATAGGTTGACCGTAAAATGGACATTCAATCTCTCGAAAGACGATGAGACGCCTTCACTTAAAGAATTGCAAAGGATCAAATGTCATGGACCTGTTGGCGGTGCTTTCTCGTATCGGAAGTTGGAGGAGAAACGCGGAAAGAAACACGGGTGTTATATACTGAGGCAATGCCAGGACGAATATAACGTGTATTATTTGGACGTTTGTACGAAAACAAGCACAACAGAAACGTACAGAATAGAATTCAAAGGTCACTGCTACATATTCAGCACTGAAGAGTACTTTAGCATTGAACGGTTGGTCAGTTGCCATCAAAATCCCGAAGGAAGAATATACCTCAACGAATGCATACCTCCCTCTGAGTATGACAAATCTCAGTTGCTTTTGTGCGGGGAACCGGTGAAGAGGGGTGTCCGCATCGACCAGGCAGAATTACAGGAGATTCTGAGGGACAACAAGAGTCCCAGGTGCTTGCCTAACAAAGACATTTTATTGTATACAGGCTCCGAGAAAACGGGCTCAGAGAATATAACGGCGACATACAAAGCTCTGTGGAGGCTAGATGAGACAAAGAAATTGTTAGTTGCGTTCAAGACACTGCAACGGGAGAGGGCCAATGACTATTTAAAGGACTTTGTAGATCTCGCAAGCAAATGGGCGTGCATACAGTCTAGTTCTATAGTTAGGCTGTATGGAGTGACTTTGAGTTCCCCGACAGCAATGGTATTGGAATATCTACCGTACGGACCGTTTGATGATTATCTGAGAGAAAACGGCGACCGTATAACGCCACTGCACTTAAAGAAGGTAGCTGCTGGTCTGGCGAGGGCGCTGTGGGACCTGTCGGAGGCGGGCGTGGTGCACGGCTACATCAGGTGCCGGAAGCTGCTGCTGGCCGTGCTCGACGCGGACCGTATTCAAGTCAAGCTATCCGGCCCCACTCTGAGACAATACACGCAGCAGGATGTACATTGGATGCCTGTAGAATTTTTCGCAGACATGAACTTAGCGAAGAGATCGGTCATTGGAGACATTTGGGCTTTCGCTACAACGCTCTGGGAAGTATTCTCGTACGGACAATTGCCAACTGAAACCAACCCCGTTTTGACAGTTAGGAGCTACGAGATGGGCGACCGCCTGCTGCGGCCGGTCCGGTGCCCGGCGGAGGTGTGGGCGCTGGTGCGGCAGTGCTGGCACGCCGACCCGCTCCGTCCGCAGGAGATCATGCGGGACATGAACCACATGCTGTATAGAGAATATGTTCCTGTACATCAATATGAAGAACCTAAGATATCTCTTGATCACATAGAGCACGCAGAAACTGTGTCGAGTGATCGTTTTATTCCGAGCGAACTGAGTGACGCGGGAAGCAACAAATCTCTTATATCGGACAACAGCGTTCCCTCTATGAATGGCACTATGTCTGATCAGTATGACAATCCCTTCGCAGACAACAAAAGTTCGAACTCGCTGGACAGCATGGCGGCCCTGATGTACGGGCTCCCCAACGAGGTGTCGTCGGCGCGTAGCACGAGCAGCGCGGGCGGCGCCGCCACGCTGGGGCTCGACGACGCGCTGCACGACTGCGACGCCTGGGCCTCCCCCAGGCTCATGGAGTCCATCGTCTCGCAGGGGAAGACCTACCTCGTCACCTTGACCAAGAAGATCGGAAGCGGAAATTACGGTCACGTATTCAAAGGTTGGATGGAGCGTGACAATCAAGAATCTCACAGAAAAGAAGTGGCGATTAAGAAATTAACCCGACAAGCCTCCGAAAGGAACGGGACTCTGTATGAAGACTTCAAAAACGAATTGGAGATTATGAAGTCATTACAACACATTAACATAGTAGAGATACTGGGCTATGCTTGGGACCAGGGACCGGAAGTTCTAATAGTCATGGAGTATCTGGAAGAAGGTTCGCTTAACTACTACCTCAAATTCCAAGGCGAAAAGCTTAGGATATCGCATCTGCTCAAATATTGTAAGGACATAGCAACGGGTATGGACCACGTGTCTGCTAAAAACGTCGTGCATCGGGATTTGGCGACGCGGAATATTCTAGTGGTGAACAAATATCACGTTAAGATATCCGACTTCGGTTTGGCCAGAATCATTCCTAAAGAAGAAAACACGTACAGACTTAAGACTGAAAGACTGTTACCAATTAACTGGTACGCCCCCGAGTCGGCCGTCGAGCCGTGGCACTTCTCGACCAAAAGCGACGTGTGGTCGTACGGTGTAACCGCCTGGGAAATATTTACACGTGCCAGACAAGAAGTTCCTAAGTTCGACGTAGATCGGCCGAGGGAAAGAGCGTCGTGTTTTCAAATACCCGAAGAATGTCCCTCCGAGATATTCAGGTACCTCATGAAGGAGTGTTGGGCTCTCGATCCGAATTTACGGCCAAGGTTTATTGACCTAATACACACATGCAAGAGATTCATAGCGGAATATCAGTAA
Protein
MATVEDIVKVAVVTNRTPNNVRCTSTLTAEELCIILCKKYNIPPLTRTLFALRVKGTDYFLKDNCKVLSGSRDYELRIRFKVPRLSLLITLDETTYDYYFQQARNDVNENKIPEIKYPEHKQELLGLGITDMTRAIAEERLPLNDVIRNYKKYIPKEIAKRHGPFPKKYAIDYLPQLSSVGHNVNYVKNLYLQQLYALAPNYLAEEYDNVLWQNGSEMTPVRVMVAPFHPHHPGIRLYNTLKREWFHVCSVEELIYLTRNGDSSVEVSRRGTPVFLKFKSEDQLSSFISVCDGYYRLTVKWTFNLSKDDETPSLKELQRIKCHGPVGGAFSYRKLEEKRGKKHGCYILRQCQDEYNVYYLDVCTKTSTTETYRIEFKGHCYIFSTEEYFSIERLVSCHQNPEGRIYLNECIPPSEYDKSQLLLCGEPVKRGVRIDQAELQEILRDNKSPRCLPNKDILLYTGSEKTGSENITATYKALWRLDETKKLLVAFKTLQRERANDYLKDFVDLASKWACIQSSSIVRLYGVTLSSPTAMVLEYLPYGPFDDYLRENGDRITPLHLKKVAAGLARALWDLSEAGVVHGYIRCRKLLLAVLDADRIQVKLSGPTLRQYTQQDVHWMPVEFFADMNLAKRSVIGDIWAFATTLWEVFSYGQLPTETNPVLTVRSYEMGDRLLRPVRCPAEVWALVRQCWHADPLRPQEIMRDMNHMLYREYVPVHQYEEPKISLDHIEHAETVSSDRFIPSELSDAGSNKSLISDNSVPSMNGTMSDQYDNPFADNKSSNSLDSMAALMYGLPNEVSSARSTSSAGGAATLGLDDALHDCDAWASPRLMESIVSQGKTYLVTLTKKIGSGNYGHVFKGWMERDNQESHRKEVAIKKLTRQASERNGTLYEDFKNELEIMKSLQHINIVEILGYAWDQGPEVLIVMEYLEEGSLNYYLKFQGEKLRISHLLKYCKDIATGMDHVSAKNVVHRDLATRNILVVNKYHVKISDFGLARIIPKEENTYRLKTERLLPINWYAPESAVEPWHFSTKSDVWSYGVTAWEIFTRARQEVPKFDVDRPRERASCFQIPEECPSEIFRYLMKECWALDPNLRPRFIDLIHTCKRFIAEYQ

Summary

Catalytic Activity
ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]
Similarity
Belongs to the protein kinase superfamily. Tyr protein kinase family.
EC Number
2.7.10.2
EMBL
KQ458575    KPJ05796.1    AGBW02013823    OWR42696.1    BABH01021456    BABH01021457    + More
BABH01021458    BABH01021459    KZ149917    PZC77917.1    KQ461073    KPJ09638.1    ODYU01000642    SOQ35759.1    GEZM01096910    JAV54487.1    DS235161    EEB12733.1    GBYB01002527    JAG72294.1    GEDC01021555    JAS15743.1    MG708321    QAB02861.1    KQ414642    KOC66704.1    GBBI01004104    JAC14608.1    GBHO01004309    GDHC01013917    JAG39295.1    JAQ04712.1    KZ288379    PBC26622.1    GEDC01010004    JAS27294.1    KK107128    QOIP01000006    EZA58280.1    RLU22133.1    KK853579    KDR06554.1    KK854124    PTY11710.1    NNAY01001988    OXU22374.1    KQ977412    KYN02881.1    KQ976553    KYM80826.1    KQ978966    KYN26896.1    GL888730    EGI58249.1    KQ981225    KYN44381.1    LBMM01002779    KMQ94378.1    LJIJ01000015    ODN05848.1    LNIX01000001    OXA64061.1    GGMS01001619    MBY70822.1    JTDY01003744    KOB69057.1    GECU01002773    JAT04934.1    ABLF02023796    ABLF02023800    PYGN01000057    PSN55899.1    CVRI01000038    CRK93974.1    JH430530    GGLE01004055    MBY08181.1    GL732527    EFX87846.1    JXUM01006685    JXUM01006686    JXUM01006687    JXUM01006688    JXUM01006689    JXUM01006690    JXUM01006691    KQ560220    KXJ83756.1    CH477896    EAT35265.2    GDIP01130422    JAL73292.1    GDIQ01209728    GDIP01071829    JAK41997.1    JAM31886.1    GDIQ01212580    JAK39145.1    AY278117    AAQ18517.1    GDIQ01135864    JAL15862.1    GDIQ01044105    JAN50632.1    GL768153    EFZ11955.1    GDIQ01214679    JAK37046.1    UFQT01001450    SSX30611.1    AXCN02000807    GDIP01208062    JAJ15340.1    GDIP01149980    JAJ73422.1    GFDF01007155    JAV06929.1    AXCM01003839    GDIQ01132818    JAL18908.1    KP310054    AKM12664.1    GGFL01004005    MBW68183.1    GGFK01004090    MBW37411.1    JQ340025    AFP74109.1    GGFJ01000975    MBW50116.1    AJWK01026286    AJWK01026287    AJWK01026288    JXJN01001847    GDIP01175820    JAJ47582.1    GDIQ01004670    JAN90067.1    ATLV01020694    KE525305    KFB45592.1    GDIQ01047748    JAN46989.1    GDIQ01059837    JAN34900.1    GDIQ01057345    JAN37392.1    GDIP01018460    JAM85255.1    EU877978    ACJ63722.1    GDIQ01046100    JAN48637.1    GGFL01004010    MBW68188.1    GDIP01090223    JAM13492.1    GDIP01162421    JAJ60981.1    GDIP01222909    JAJ00493.1    GDIP01104933    JAL98781.1    MNPL01022345    OQR69047.1    HACA01022148    CDW39509.1    CAEY01000797    GGFJ01001522    MBW50663.1   
Pfam
PF07714   Pkinase_Tyr        + More
PF18379   FERM_F1
PF17887   Jak1_Phl
PF00017   SH2
PF18377   FERM_F2
PF00373   FERM_M
Interpro
IPR000719   Prot_kinase_dom        + More
IPR020635   Tyr_kinase_cat_dom       
IPR036860   SH2_dom_sf       
IPR008266   Tyr_kinase_AS       
IPR017441   Protein_kinase_ATP_BS       
IPR011009   Kinase-like_dom_sf       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR000299   FERM_domain       
IPR019749   Band_41_domain       
IPR019748   FERM_central       
IPR016251   Tyr_kinase_non-rcpt_Jak/Tyk2       
IPR041381   Jak1_PHL_dom       
IPR041155   FERM_F1       
IPR035963   FERM_2       
IPR000980   SH2       
IPR041046   FERM_F2       
IPR014352   FERM/acyl-CoA-bd_prot_sf       
SUPFAM
SSF56112   SSF56112        + More
SSF55550   SSF55550       
SSF47031   SSF47031       
Gene 3D
PDB
4UEU     E-value=1.33623e-41,     Score=431

Ontologies

Topology

Length:
1114
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.00359000000000001
Exp number, first 60 AAs:
0.00146
Total prob of N-in:
0.00017
outside
1  -  1114
 
 

Population Genetic Test Statistics

Pi
19.195598
Theta
169.657756
Tajima's D
0.458444
CLR
0.672545
CSRT
0.495175241237938
Interpretation
Uncertain
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