Gene

KWMTBOMO11554

Pre Gene Modal

BGIBMGA004077

Annotation

PREDICTED:_solute_carrier_family_35_member_F5_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr19(+):7981855-7986880      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit I      

Location in the cell

PlasmaMembrane   Reliability : 3.871

CDS

ATGACAAAATATTTATACACTGAAAAACACTTAGAGAGACCGTTTCTTGTGACTTACGTGAGAAGCTCATTACTATTTATATATCTCTTAGTTTTGTGTTTTTCACCTCCTACAAAGGATCCTTGTCGACCAACTGATTACACTCAATTATTAGAGCCTACAGCAGAAACGGATGATGAAAGCTTCTTTACTGAATCCAATGGTGATTCAACATTTATACCGGTCAGAGCGGGGGAAACAACCGACAGTGACGATGCTGCACCCAGAGCTGTCCGTTTTAATAAAGTTGCTGAGGTACGAGTTATGTCAGCAGCGATGGCCAGTGAAGCGTTGTTGGCCCGATTATCTTGGGCGGCCTCAGAACGTGCTGCGCAAGTTGCACAGAGGCGTGCCGCTGCAGCCGCCACAAGACGACATCTGCGTTTAGCATTGTTCTTGTCTATGCCTTGGTTCATATCAAACTATCTGTACCGTTTAAGTATACTGCACACATCAACTAGTTCAGCTACAATGTACACATCTACAACGGGCGCCTTCGTTCTTACCCTGGGAGCTATATTTGCAGAAGTACCAACGGATCGGTTCACAATCTCGAAAAGTGTTGCCGTTCTTTTAACTGCAGCCGGCTTGGTGGTGCTCGGAATATCGGAGAGCCATCAGAGTAACTGGACGGCGGTGTTGTCAGCACTTGGTTCGGCATTTTGCTACGCAATACATCTTTTGTTGTTCAGAAGAGAATTGAGGAAAGGAGAAGGCATAAACTCACCATTACTGATTGGCAAAAGTGACTAA

Protein

MTKYLYTEKHLERPFLVTYVRSSLLFIYLLVLCFSPPTKDPCRPTDYTQLLEPTAETDDESFFTESNGDSTFIPVRAGETTDSDDAAPRAVRFNKVAEVRVMSAAMASEALLARLSWAASERAAQVAQRRAAAAATRRHLRLALFLSMPWFISNYLYRLSILHTSTSSATMYTSTTGAFVLTLGAIFAEVPTDRFTISKSVAVLLTAAGLVVLGISESHQSNWTAVLSALGSAFCYAIHLLLFRRELRKGEGINSPLLIGKSD

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Similarity

Belongs to the eIF-3 subunit I family.

Uniprot

A0A2H1VLK3   A0A2W1BYL0   A0A2A4JMQ6   A0A3S2N7T1   A0A212FJQ1   A0A194R1C4   + More
A0A194QJN8   H9J3J0   E2BHK4   A0A1B0GIH8   A0A151WNV4   A0A0N0BJD6   A0A158NUS0   U5EQY9   A0A151K0F9   A0A026X456   F4WE12   A0A0L7R1S8   A0A088A651   A0A151I6I0   A0A2A3EL11   A0A1B6DQK8   A0A154P5U6   A0A151IV32   A0A195BBE9   A0A1W7R819   A0A023ETE1   Q16IG8   A0A2J7RHH1   A0A0C9R4N9   A0A1B6JZ50   A0A1A9XPB3   A0A1B0BG77   A0A1A9UZA6   A0A1I8MAQ3   B3MEC0   A0A1Q3F5E1   A0A1Q3F5J7   D6WTY2   A0A1B0A7H5   A0A1B0FKK8   B0WHL1   A0A3B0JJX6   A0A232F3M4   B3NQB2   K7J444   A0A1I8P6V4   A0A1L8DF42   A0A1L8DEY1   A0A1Y1MI94   A0A1J1IKA1   Q7K3M9   B4GGC0   Q28XM1   A0A182WHV8   A0A0J9RDH0   B4HS59   B4QGW5   B4P7B5   A0A1W4WCD1   A0A1B0DD65   A0A182QUS1   B4MQG6   A0A182NLR3   A0A182V397   A0A182Y335   A0A182JXV7   A0A182TDD3   A0A182WWK4   A0A182L3J7   Q7PT68   A0A182I6T8   A0A182IK23   A0A1A9W2D5   A0A182P115   A0A182RGS4   A0A182MKR5   A0A0L0BP74   B4LMM8   A0A034V8X5   A0A0K8TYR0   A0A1L8DDF5   A0A0A9ZAW5   A0A146LTQ2   A0A0A1XKG2   A0A2M4AHJ2   B4J4I0   N6SRM7   W8C4I4   A0A0Q9W2H9   A0A2M4AE70   A0A2M4BNA5   A0A2M3Z5E3   W5J8K0   A0A182FGA4  

Pubmed

28756777    22118469    26354079    19121390    20798317    21347285    + More
24508170    30249741    21719571    24945155    17510324    25315136    17994087    18057021    18362917    19820115    28648823    20075255    28004739    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    23185243    22936249    17550304    25244985    20966253    12364791    14747013    17210077    26108605    25348373    25401762    26823975    25830018    23537049    24495485    20920257    23761445   

EMBL

ODYU01003225    SOQ41705.1    KZ149917    PZC77910.1    NWSH01001023    PCG73066.1    + More
RSAL01000235    RVE43760.1    AGBW02008244    OWR53961.1    KQ461073    KPJ09646.1    KQ458575    KPJ05788.1    BABH01021443    GL448301    EFN84857.1    AJWK01014145    KQ982905    KYQ49500.1    KQ435719    KOX78848.1    ADTU01026688    GANO01003053    JAB56818.1    KQ981296    KYN43090.1    KK107030    QOIP01000012    EZA62149.1    RLU16160.1    GL888102    EGI67450.1    KQ414667    KOC64820.1    KQ978473    KYM93701.1    KZ288229    PBC31701.1    GEDC01009333    JAS27965.1    KQ434809    KZC06510.1    KQ980926    KYN11387.1    KQ976532    KYM81552.1    GEHC01000365    JAV47280.1    GAPW01001482    JAC12116.1    CH478078    CH477517    EAT34062.1    EAT39645.1    NEVH01003743    PNF40267.1    GBYB01001763    GBYB01001765    GBYB01001766    JAG71530.1    JAG71532.1    JAG71533.1    GECU01003237    JAT04470.1    JXJN01013800    CH902619    EDV36526.1    KPU76277.1    KPU76278.1    GFDL01012260    JAV22785.1    GFDL01012246    JAV22799.1    KQ971352    EFA07349.1    CCAG010016793    DS231938    EDS27860.1    OUUW01000001    SPP75680.1    NNAY01001108    OXU25109.1    CH954179    EDV55888.1    AAZX01000993    GFDF01009079    JAV05005.1    GFDF01009078    JAV05006.1    GEZM01030673    JAV85434.1    CVRI01000054    CRL00186.1    AE013599    AY058472    AAF58122.2    AAL13701.1    CH479183    EDW35540.1    CM000071    EAL26295.1    KRT02975.1    CM002911    KMY94027.1    CH480816    EDW48006.1    CM000362    EDX07228.1    CM000158    EDW92060.1    AJVK01031686    AJVK01031687    AXCN02000966    CH963849    EDW74355.1    AAAB01008807    EAA04392.4    APCN01003701    AXCM01003930    JRES01001578    KNC21816.1    CH940648    EDW60015.1    GAKP01020939    JAC38013.1    GDHF01033104    GDHF01032110    GDHF01029303    JAI19210.1    JAI20204.1    JAI23011.1    GFDF01009598    JAV04486.1    GBHO01004654    JAG38950.1    GDHC01007508    JAQ11121.1    GBXI01015715    GBXI01003832    GBXI01003244    JAC98576.1    JAD10460.1    JAD11048.1    GGFK01006938    MBW40259.1    CH916367    EDW01662.1    APGK01059441    APGK01059442    KB741293    KB632046    ENN70274.1    ERL88283.1    GAMC01009582    GAMC01009581    JAB96974.1    KRF79197.1    GGFK01005763    MBW39084.1    GGFJ01005425    MBW54566.1    GGFM01002988    MBW23739.1    ADMH02001954    ETN60291.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000053240    UP000053268    UP000005204    + More
UP000008237    UP000092461    UP000075809    UP000053105    UP000005205    UP000078541    UP000053097    UP000279307    UP000007755    UP000053825    UP000005203    UP000078542    UP000242457    UP000076502    UP000078492    UP000078540    UP000008820    UP000235965    UP000092443    UP000092460    UP000078200    UP000095301    UP000007801    UP000007266    UP000092445    UP000092444    UP000002320    UP000268350    UP000215335    UP000008711    UP000002358    UP000095300    UP000183832    UP000000803    UP000008744    UP000001819    UP000075920    UP000001292    UP000000304    UP000002282    UP000192221    UP000092462    UP000075886    UP000007798    UP000075884    UP000075903    UP000076408    UP000075881    UP000075902    UP000076407    UP000075882    UP000007062    UP000075840    UP000075880    UP000091820    UP000075885    UP000075900    UP000075883    UP000037069    UP000008792    UP000001070    UP000019118    UP000030742    UP000000673    UP000069272   

PRIDE

H9J3J0    Q7K3M9   

Pfam

PF00892   EamA        + More
PF00400   WD40

Interpro

IPR036259   MFS_trans_sf        + More
IPR000620   EamA_dom       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR017986   WD40_repeat_dom       
IPR001680   WD40_repeat       
IPR019775   WD40_repeat_CS       
IPR027525   eIF3i       
IPR036322   WD40_repeat_dom_sf       

SUPFAM

SSF103473   SSF103473        + More
SSF50978   SSF50978       

Gene 3D

2.130.10.10    

ProteinModelPortal

A0A2H1VLK3   A0A2W1BYL0   A0A2A4JMQ6   A0A3S2N7T1   A0A212FJQ1   A0A194R1C4   + More
A0A194QJN8   H9J3J0   E2BHK4   A0A1B0GIH8   A0A151WNV4   A0A0N0BJD6   A0A158NUS0   U5EQY9   A0A151K0F9   A0A026X456   F4WE12   A0A0L7R1S8   A0A088A651   A0A151I6I0   A0A2A3EL11   A0A1B6DQK8   A0A154P5U6   A0A151IV32   A0A195BBE9   A0A1W7R819   A0A023ETE1   Q16IG8   A0A2J7RHH1   A0A0C9R4N9   A0A1B6JZ50   A0A1A9XPB3   A0A1B0BG77   A0A1A9UZA6   A0A1I8MAQ3   B3MEC0   A0A1Q3F5E1   A0A1Q3F5J7   D6WTY2   A0A1B0A7H5   A0A1B0FKK8   B0WHL1   A0A3B0JJX6   A0A232F3M4   B3NQB2   K7J444   A0A1I8P6V4   A0A1L8DF42   A0A1L8DEY1   A0A1Y1MI94   A0A1J1IKA1   Q7K3M9   B4GGC0   Q28XM1   A0A182WHV8   A0A0J9RDH0   B4HS59   B4QGW5   B4P7B5   A0A1W4WCD1   A0A1B0DD65   A0A182QUS1   B4MQG6   A0A182NLR3   A0A182V397   A0A182Y335   A0A182JXV7   A0A182TDD3   A0A182WWK4   A0A182L3J7   Q7PT68   A0A182I6T8   A0A182IK23   A0A1A9W2D5   A0A182P115   A0A182RGS4   A0A182MKR5   A0A0L0BP74   B4LMM8   A0A034V8X5   A0A0K8TYR0   A0A1L8DDF5   A0A0A9ZAW5   A0A146LTQ2   A0A0A1XKG2   A0A2M4AHJ2   B4J4I0   N6SRM7   W8C4I4   A0A0Q9W2H9   A0A2M4AE70   A0A2M4BNA5   A0A2M3Z5E3   W5J8K0   A0A182FGA4  

KEGG

101747064    K15289 solute carrier family 35, member F5 | (RefSeq) solute carrier family 35 member F5

GO

GO:0016021   GO:0033290   GO:0016282   GO:0001732   GO:0005852   GO:0003743  

Subcellular location

Cytoplasm  

Length:

263

Number of predicted TMHs:

5

Exp number of AAs in TMHs:

103.01837

Exp number, first 60 AAs:

19.76816

Total prob of N-in:

0.06199

POSSIBLE N-term signal

sequence

outside

1  -  14

TMhelix

15  -  34

inside

35  -  138

TMhelix

139  -  161

outside

162  -  170

TMhelix

171  -  190

inside

191  -  196

TMhelix

197  -  216

outside

217  -  220

TMhelix

221  -  243

inside

244  -  263

 

 

Pi

164.049641

Theta

183.556563

Tajima's D

0.013585

CLR

111.488683

CSRT

0.380130993450327

Interpretation

Uncertain