Gene

KWMTBOMO11527

Pre Gene Modal

BGIBMGA004064

Annotation

glutamyl-tRNA_amidotransferase_subunit_B_[Bombyx_mori]

Location

Bomo_Chr19(+):7750915-7758047      View in EpiBrowser

Full name

Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial      

Alternative Name

Cytochrome oxidase assembly factor PET112 homolog
PET112-like

Location in the cell

Cytoplasmic   Reliability : 2.311

CDS

ATGCAGCCATACCAGGTATTCACACCAGGATTTCACAAAAAGCCTTACAAGAAAAGCTCAAAAATAAAACAAATTCAATTGGAACAAGACAGTGGGAAATCTCTGCATGATGCAGAACTTAAAAGAAGCTTAGTTGACCTGAATAGAGCAGGGGCTCCACTCATAGAAGTTGTATTTGAACCAGATTTACAGGATGGCGAAGAAGCTGCAGCTTTGGTCAAGGAATTGGTATTGATTGTGCAGCGTCTTGGGGCATGTACAGGTCGGATGGAAGAGGGCGCACTACGTGTTGATGCTAATGTTTCTATACGACGTCCAGGAGATCCCTTATCCACTCGAACTGAGATTAAGAACATCGGTTCAATTAGAGGCGTCGCCGGCGCTGTTCGATACGAAATCGAACGCCAGAAGACCGTGCTTGAGAATGGAGGTCGTATCATCAACGAAACGCGAGCTTGGGACGCCGTAGGCAGAGCCACCATACCAATGAGGGACAAAGAAGTTGTACAAGACTATAGATACATGCCCGAGCCGAATTTACCGCCTTTACGAGTCAATTTGAAATCAAAACACGATACACAACACGTTATCAGCGTGCCCTTGATACAAGAACAGATTCCTGAATTACCGGAAAGTTCTCGAAAAAACCTCATAGAGAACTACCAGTTGCGTCCCGAAGCGGCGATTCAAATCGTCAATGAGCCCATCTTACTGAAATACTTCGTCGATCTGGCCGAGGAAAGAAGTCAATCCACTAAAATAGCAAATTTATTAATTAACGAGCTACTGACGGTGCTTAATAAAAATAAATTAGACATTTCCGACTGTCCCATTACATTGAGGCAGCTAAAAGAACTATTTAAATTGTTTTTCGATAAAAAAATCAGTTTGGAAGTATTCAAGAATGTCTTAGACGACCTAGTGATTTCTTCGGACAGTGATAAAATGCCCTCGAAAATTATTCAAGAGAGAAACTGGACATTGATAAGTGACGAAACTGAAATAACCAAATTTTGTATTGAAATAATTGAAAATAATCCGAAATTAGTAAAACAATACAAGGAAGGAAAAGTGAAAGTACTGAAGGCATTGTTGGGCGTAATGTCTAAGAATTCTCAAAATAAATTCGATATGTCTTTAGCGTCTAGAATAATGGAAGAGGTATTGAAAAAGTAA

Protein

MQPYQVFTPGFHKKPYKKSSKIKQIQLEQDSGKSLHDAELKRSLVDLNRAGAPLIEVVFEPDLQDGEEAAALVKELVLIVQRLGACTGRMEEGALRVDANVSIRRPGDPLSTRTEIKNIGSIRGVAGAVRYEIERQKTVLENGGRIINETRAWDAVGRATIPMRDKEVVQDYRYMPEPNLPPLRVNLKSKHDTQHVISVPLIQEQIPELPESSRKNLIENYQLRPEAAIQIVNEPILLKYFVDLAEERSQSTKIANLLINELLTVLNKNKLDISDCPITLRQLKELFKLFFDKKISLEVFKNVLDDLVISSDSDKMPSKIIQERNWTLISDETEITKFCIEIIENNPKLVKQYKEGKVKVLKALLGVMSKNSQNKFDMSLASRIMEEVLKK

Description

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).

Catalytic Activity

ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate

Subunit

Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.
Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

Miscellaneous

This protein may be expected to contain an N-terminal transit peptide but none has been predicted.

Similarity

Belongs to the GatB/GatE family. GatB subfamily.

Keywords

ATP-binding   Complete proteome   Ligase   Mitochondrion   Nucleotide-binding   Protein biosynthesis   Reference proteome   Transit peptide  

Feature

chain  Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

Uniprot

Q2F5Z7   H9J3H7   A0A2A4J252   A0A2H1WX97   A0A2W1BYY5   A0A212FG01   + More
A0A194QXJ6   S4PAG7   A0A194QJP0   B0W3H3   A0A182NKX8   A0A182R840   A0A182G6W7   A0A182QS31   A0A1Q3FED1   A0A2J7QEG7   Q16UG2   A0A2K7P6C3   A0A1E1W711   Q7QDG7   A0A182XK37   A0A182K571   A0A182YM49   D6WI92   A0A182HJV4   A0A182GEU7   A0A182UW84   A0A182KX38   A0A067RD99   A0A0A1XRW9   A0A2M4AV30   A0A182VS98   A0A182TKY4   A0A182F8K4   A0A182PN03   A0A069DSQ0   A0A0K8U5Q8   A0A034W247   B4K7D9   A0A1L8E0Y9   E2ADG6   W5JDE6   A0A182J447   B4JIG5   A0A3B0JK37   I4DNB0   A0A0V0GCZ9   A0A084VJN3   A0A0J7KA46   W8BW36   A0A182MJV3   A0A3B0JP73   A0A0M4EVN4   A0A1W4V4L8   B4G419   Q298K0   B4NBN1   A0A1I8MLI1   B4QSG5   B4MBY8   A0A1I8PS52   B4HGI1   A0A1W4WXK0   B3P793   Q9VCD0   B3M0M1   B4PL18   F4WIU4   A0A1A9XI12   R4FMS1   A0A1B0BJM7   D3TL29   N6TYZ9   A0A026VUI0   A0A1B0G868   A0A3L8E4A0   A0A1B6FUR5   A0A1A9ZLB9   A0A1A9VR00   A0A0A9YG45   A0A0K8TDE5   A0A1A9X188   A0A0M8ZPW2   A0A226E6T8   K7J9N8   A0A2P8XUS1   A0A1D2NDS1   A0A232F6N4   A0A336KRT3   A0A2S2QYB1   A0A2A3E4R0   A0A1W4YS05   G3MF25   A0A3B5ACH2   A0A224YTX6   A0A3B4X5H4   T1J1Q9  

EC Number

6.3.5.-

Pubmed

19121390    28756777    22118469    26354079    23622113    26483478    + More
17510324    12364791    14747013    17210077    25244985    18362917    19820115    20966253    24845553    25830018    26334808    25348373    17994087    20798317    20920257    23761445    22651552    24438588    24495485    15632085    25315136    10731132    12537572    17550304    21719571    20353571    23537049    24508170    30249741    25401762    20075255    29403074    27289101    28648823    22216098    28797301   

EMBL

DQ311275    ABD36220.1    BABH01021420    BABH01021421    NWSH01004136    PCG65463.1    + More
ODYU01011755    SOQ57681.1    KZ149917    PZC77886.1    AGBW02008742    OWR52657.1    KQ461073    KPJ09680.1    GAIX01005026    JAA87534.1    KQ458575    KPJ05747.1    DS231831    JXUM01045618    KQ561444    KXJ78572.1    AXCN02000108    GFDL01009183    JAV25862.1    NEVH01015312    PNF26975.1    CH477622    GDQN01008317    JAT82737.1    AAAB01008851    EAA07363.5    KQ971321    EFA01448.2    APCN01002209    JXUM01058747    KQ562016    KXJ76897.1    KK852542    KDR21732.1    GBXI01000551    JAD13741.1    GGFK01011328    MBW44649.1    GBGD01001766    JAC87123.1    GDHF01030335    JAI21979.1    GAKP01010540    GAKP01010537    JAC48412.1    CH933806    EDW14263.2    GFDF01001717    JAV12367.1    GL438750    EFN68528.1    ADMH02001543    ETN62111.1    CH916369    EDV93046.1    OUUW01000007    SPP82714.1    AK402817    BAM19400.1    GECL01000500    JAP05624.1    ATLV01013823    KE524901    KFB38177.1    LBMM01010938    KMQ87139.1    GAMC01009091    GAMC01009089    JAB97466.1    AXCM01000679    SPP82713.1    CP012526    ALC47430.1    CH479179    EDW24430.1    CM000070    EAL27955.2    CH964232    EDW81195.1    CM000364    EDX14164.1    CH940656    EDW58609.1    CH480815    EDW43434.1    CH954182    EDV53913.1    AE014297    CH902617    EDV44268.1    CM000160    EDW99003.2    GL888177    EGI65890.1    GAHY01001614    JAA75896.1    JXJN01015472    EZ422125    ADD18324.1    APGK01049576    KB741156    ENN73561.1    KK107928    EZA47136.1    CCAG010000199    QOIP01000001    RLU27303.1    GECZ01027682    GECZ01015807    GECZ01009894    JAS42087.1    JAS53962.1    JAS59875.1    GBHO01012471    GBHO01012470    GBHO01012469    GBHO01012468    JAG31133.1    JAG31134.1    JAG31135.1    JAG31136.1    GBRD01002390    JAG63431.1    KQ436022    KOX67556.1    LNIX01000006    OXA53315.1    AAZX01008474    PYGN01001314    PSN35757.1    LJIJ01000081    ODN03245.1    NNAY01000786    OXU26514.1    UFQS01000677    UFQT01000677    SSX06115.1    SSX26471.1    GGMS01013566    MBY82769.1    KZ288386    PBC26474.1    JO840476    AEO32093.1    GFPF01006136    MAA17282.1    JH431789   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000053268    UP000002320    + More
UP000075884    UP000075900    UP000069940    UP000249989    UP000075886    UP000235965    UP000008820    UP000007062    UP000076407    UP000075881    UP000076408    UP000007266    UP000075840    UP000075903    UP000075882    UP000027135    UP000075920    UP000075902    UP000069272    UP000075885    UP000009192    UP000000311    UP000000673    UP000075880    UP000001070    UP000268350    UP000030765    UP000036403    UP000075883    UP000092553    UP000192221    UP000008744    UP000001819    UP000007798    UP000095301    UP000000304    UP000008792    UP000095300    UP000001292    UP000192223    UP000008711    UP000000803    UP000007801    UP000002282    UP000007755    UP000092443    UP000092460    UP000019118    UP000053097    UP000092444    UP000279307    UP000092445    UP000078200    UP000091820    UP000053105    UP000198287    UP000002358    UP000245037    UP000094527    UP000215335    UP000242457    UP000192224    UP000261400    UP000261360   

PRIDE

Q2F5Z7    H9J3H7    Q9VCD0   

Pfam

PF02934   GatB_N        + More
PF02637   GatB_Yqey

Interpro

IPR018027   Asn/Gln_amidotransferase        + More
IPR017959   Asn/Gln-tRNA_amidoTrfase_suB/E       
IPR004413   Apn/Gln-ADT_bsu       
IPR042114   GatB_C_1       
IPR006075   Asn/Gln-tRNA_Trfase_suB/E_cat       
IPR003789   Asn/Gln_tRNA_amidoTrase-B-like       
IPR023168   GatB_Yqey_C_2       
IPR014746   Gln_synth/guanido_kin_cat_dom       
IPR017958   Gln-tRNA_amidoTrfase_suB_CS       

SUPFAM

SSF55931   SSF55931        + More
SSF89095   SSF89095       

Gene 3D

1.10.10.410     1.10.150.380    

ProteinModelPortal

Q2F5Z7   H9J3H7   A0A2A4J252   A0A2H1WX97   A0A2W1BYY5   A0A212FG01   + More
A0A194QXJ6   S4PAG7   A0A194QJP0   B0W3H3   A0A182NKX8   A0A182R840   A0A182G6W7   A0A182QS31   A0A1Q3FED1   A0A2J7QEG7   Q16UG2   A0A2K7P6C3   A0A1E1W711   Q7QDG7   A0A182XK37   A0A182K571   A0A182YM49   D6WI92   A0A182HJV4   A0A182GEU7   A0A182UW84   A0A182KX38   A0A067RD99   A0A0A1XRW9   A0A2M4AV30   A0A182VS98   A0A182TKY4   A0A182F8K4   A0A182PN03   A0A069DSQ0   A0A0K8U5Q8   A0A034W247   B4K7D9   A0A1L8E0Y9   E2ADG6   W5JDE6   A0A182J447   B4JIG5   A0A3B0JK37   I4DNB0   A0A0V0GCZ9   A0A084VJN3   A0A0J7KA46   W8BW36   A0A182MJV3   A0A3B0JP73   A0A0M4EVN4   A0A1W4V4L8   B4G419   Q298K0   B4NBN1   A0A1I8MLI1   B4QSG5   B4MBY8   A0A1I8PS52   B4HGI1   A0A1W4WXK0   B3P793   Q9VCD0   B3M0M1   B4PL18   F4WIU4   A0A1A9XI12   R4FMS1   A0A1B0BJM7   D3TL29   N6TYZ9   A0A026VUI0   A0A1B0G868   A0A3L8E4A0   A0A1B6FUR5   A0A1A9ZLB9   A0A1A9VR00   A0A0A9YG45   A0A0K8TDE5   A0A1A9X188   A0A0M8ZPW2   A0A226E6T8   K7J9N8   A0A2P8XUS1   A0A1D2NDS1   A0A232F6N4   A0A336KRT3   A0A2S2QYB1   A0A2A3E4R0   A0A1W4YS05   G3MF25   A0A3B5ACH2   A0A224YTX6   A0A3B4X5H4   T1J1Q9  

PDB

3H0R     E-value=6.97259e-51,     Score=507

KEGG

693097    K02434 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] | (RefS

PATHWAY

00970    Aminoacyl-tRNA biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0070681   GO:0005739   GO:0030956   GO:0005524   GO:0016740   GO:0050567   GO:0032543   GO:0016884   GO:0006425   GO:0016874   GO:0000413   GO:0016020   GO:0016021   GO:0004888   GO:0007166   GO:0003707   GO:0006418   GO:0003824  

PANTHER

PTHR11659  

Subcellular location

Mitochondrion  

Length:

391

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00460

outside

1  -  391

 

 

Pi

218.569947

Theta

149.376404

Tajima's D

1.190888

CLR

0.171522

CSRT

0.712414379281036

Interpretation

Uncertain