Gene

KWMTBOMO11515  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004054

Annotation

PREDICTED:_maspardin-like_[Amyelois_transitella]

Location

Bomo_Chr19(-):7566876-7570544      View in EpiBrowser

Full name

Maspardin      

Alternative Name

Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog

Location in the cell

PlasmaMembrane   Reliability : 1.585

CDS

ATGAGTTGTGCTAGCGAATTATCTCAGTCGCATGAGTATCTAAGTTTCCGAAGCAGCATTCCTTTAAGAAAAATCGTAGTAGACTCGGATAATTCCAAGGCATGGAAAATATTTGATAGTGGACCAAGGTCAGTTGCATGTCCTTTAATATGTTTACCTCCAGTTTCTGGAACAGCTGATATTTATTACAAGCAAGTTATGGGCCTAGCATCACGAGGCGTTCGAGTCATATCTGCAGAGGCTCCTCCTTATTGGAATTTAAAAGAATGGTGTGATGGTTTCAAAAGACTCATTGATATATTAGAGCTTGGTAAAGTGCACATATTCGGAGCATCTTTAGGAGGATTCATAGCCCAAAAATTTGCAGAACTGACCAGAAATTTTCCTCGTGTCGCATCACTTGTTCTGTGTAACACATTTGCGGATACGTCTGTTTTTGAATACAATGACTCAGCAGCATTATTTTGGTTACTTCCATCACTAGTTTTGAAAAGAATGTTAATGGGAAATTTTACTACTGACAAAGTCGATACACGTATGGCCGAGTCAATTGATTTTATGGTTGAAAAGCTAGAAACTCTGACGCAATCAGAATTAGCATCTAGATTGACATTGAACTGCACTCCGAATTATGTGCAACCACATTTATTAAGCGACATTCCAGTTACGATTATGGATGTTTGGGACGAAAGTGCACTTAGTTCACACGTACGTGAAGATTTGTATAAATCTTACCCTCATGCGAAGCTAGCGCATCTCAAGAGCGGTGGCAACTTTCCTTATCTTAGTAGAAGCGACGAAGTTAATTTGCATCTGTTGATACATTTAAGACAGTTTGATGGTACAGAGCTTTCGTCGTCGTATCTCAGTTTGCACAAAATGCCGCCATCCCAATCTCCCACAGACTCGGAAGAGAGCCCCATCAACTATTTTAACCAAAGTGAAAAATATGTGCAAATTTCATGA

Protein

MSCASELSQSHEYLSFRSSIPLRKIVVDSDNSKAWKIFDSGPRSVACPLICLPPVSGTADIYYKQVMGLASRGVRVISAEAPPYWNLKEWCDGFKRLIDILELGKVHIFGASLGGFIAQKFAELTRNFPRVASLVLCNTFADTSVFEYNDSAALFWLLPSLVLKRMLMGNFTTDKVDTRMAESIDFMVEKLETLTQSELASRLTLNCTPNYVQPHLLSDIPVTIMDVWDESALSSHVREDLYKSYPHAKLAHLKSGGNFPYLSRSDEVNLHLLIHLRQFDGTELSSSYLSLHKMPPSQSPTDSEESPINYFNQSEKYVQIS

Description

May play a role as a negative regulatory factor in CD4-dependent T-cell activation.

Subunit

Interacts with CD4.

Similarity

Belongs to the AB hydrolase superfamily.

Keywords

Complete proteome   Cytoplasm   Reference proteome   Phosphoprotein  

Feature

chain  Maspardin

Uniprot

H9J3G7   A0A2A4JA43   A0A2W1BJX3   A0A023PTS0   A0A2H1VPK8   A0A194QWL0   + More
A0A194QQD3   A0A212EPN2   A0A154NXS6   K7IZF2   A0A2A3ERE4   A0A088AUM4   A0A0C9RN80   A0A0L7R7R7   A0A310SN11   A0A0J7KI73   A0A1W4X753   I4DKW8   A0A1Y1KNB7   A0A026VW30   A0A151X472   A0A195CNP6   F4WE58   V5I7Z6   A0A067RGW5   A0A151I5W9   A0A158NAN2   A0A151IYN0   A0A0T6AWI4   E2B4Y5   D6WQD6   A0A1Y1KJW9   A0A1B6GIW3   A0A1B6JK98   A0A1B6M629   A0A023F3Z1   A0A0K8RP44   A0A069DS48   A0A0V0G9A9   A0A224YUY1   A0A131Z339   L7LX54   T1IBN9   A0A131XEU9   A0A151JYJ7   A0A0A9YZX7   R4V3E9   A0A1E1XGI1   A0A023GBB4   A0A224XTV9   A0A1B6D4C4   A0A1B6CEJ9   E0VQU6   N6UAR4   A0A1W7RA91   A0A0P4WHT9   A7SGB1   A0A087UNC4   A0A1Z5KXD1   A0A293N5I5   T1JNR9   A0A226EVY6   F8W490   E9HMP4   F1QFZ2   H2ZSC3   H9G9D1   A0A2D0RV26   Q6PC62   K4FT91   J3SCL2   T1DKH7   A0A3Q3IVX3   A0A250YFE2   A0A0P7VTU9   L8IAZ0   Q8MJJ1   A0A098LXE7   A0A2Y9DHH4   A0A2D4FPI9   W5N9S1   A0A091KM28   A0A287D169   A0A1S3EMX4   U6CUR2   A0A2Y9KF64   M3XN72   A0A091DT71   A0A1W7RFZ6   E2QSZ2   G3SQV6   A0A2Y9HCU8   A0A2U3WKP8   A0A3Q7TPQ7   E1C0Z8   A0A0N8K1A4   F1S1X1   W5Q8G9   A0A0N8BI17   A0A341AM74  

Pubmed

19121390    28756777    22729480    26354079    22118469    20075255    + More
22651552    28004739    24508170    21719571    24845553    21347285    20798317    18362917    19820115    25474469    26334808    28797301    26830274    25576852    28049606    25401762    26823975    28503490    20566863    23537049    17615350    28528879    23594743    21292972    9215903    21881562    15520368    23056606    23025625    23758969    25727380    28087693    22751099    12131876    26358130    16341006    15592404    30723633    20809919   

EMBL

BABH01021400    BABH01021401    BABH01021402    BABH01021403    BABH01021404    BABH01021405    + More
BABH01021406    BABH01021407    NWSH01002390    PCG68404.1    KZ150235    PZC71973.1    JQ993446    AHX36980.1    ODYU01003670    SOQ42736.1    KQ461073    KPJ09694.1    KQ458575    KPJ05736.1    AGBW02013432    OWR43448.1    KQ434778    KZC04413.1    KZ288192    PBC34260.1    GBYB01008541    JAG78308.1    KQ414638    KOC66879.1    KQ759862    OAD62522.1    LBMM01007016    KMQ90118.1    AK401936    BAM18558.1    GEZM01081332    JAV61700.1    KK107730    EZA47967.1    KQ982557    KYQ55074.1    KQ977481    KYN02363.1    GL888102    EGI67496.1    GALX01005570    JAB62896.1    KK852646    KDR19527.1    KQ976425    KYM88100.1    ADTU01000017    KQ980763    KYN13505.1    LJIG01022678    KRT79291.1    GL445681    EFN89249.1    KQ971354    EFA06956.1    GEZM01081331    GEZM01081330    JAV61702.1    GECZ01029329    GECZ01027415    GECZ01027166    GECZ01022900    GECZ01020938    GECZ01011760    GECZ01008952    GECZ01008640    GECZ01007776    GECZ01007395    JAS40440.1    JAS42354.1    JAS42603.1    JAS46869.1    JAS48831.1    JAS58009.1    JAS60817.1    JAS61129.1    JAS61993.1    JAS62374.1    GECU01008072    JAS99634.1    GEBQ01031168    GEBQ01008595    JAT08809.1    JAT31382.1    GBBI01003038    JAC15674.1    GADI01001414    JAA72394.1    GBGD01002417    JAC86472.1    GECL01001370    JAP04754.1    GFPF01009589    MAA20735.1    GEDV01004016    JAP84541.1    GACK01008649    JAA56385.1    ACPB03006487    GEFH01003709    JAP64872.1    KQ981463    KYN41518.1    GBHO01005815    GBRD01002671    GDHC01000260    JAG37789.1    JAG63150.1    JAQ18369.1    KC632499    AGM32313.1    GFAC01000813    JAT98375.1    GBBM01003932    JAC31486.1    GFTR01004566    JAW11860.1    GEDC01016873    JAS20425.1    GEDC01025432    JAS11866.1    DS235442    EEB15752.1    APGK01042108    KB741002    KB631984    ENN75722.1    ERL87711.1    GFAH01000342    JAV48047.1    GDRN01051308    JAI66407.1    DS469651    EDO37239.1    KK120696    KFM78863.1    GFJQ02007519    JAV99450.1    GFWV01022734    MAA47461.1    AFFK01014481    LNIX01000001    OXA61773.1    CABZ01075441    CU929410    GL732688    EFX67004.1    AFYH01244460    AFYH01244461    AAWZ02026864    AY394947    BC059461    JX052336    AFK10564.1    JU175024    GBEX01001924    AFJ50550.1    JAI12636.1    GAAZ01001358    GBKC01002019    GBKD01001215    JAA96585.1    JAG44051.1    JAG46403.1    GFFW01002549    JAV42239.1    JARO02000728    KPP77588.1    JH881599    ELR53336.1    AF451182    BC118320    GBSI01001324    JAC95172.1    IACJ01087070    LAA49395.1    AHAT01024789    AHAT01024790    KK534035    KFP28869.1    AGTP01003205    AGTP01003206    HAAF01001736    CCP73562.1    AEYP01047069    AEYP01047070    AEYP01047071    KN123265    KFO25996.1    GDAY02001363    JAV50064.1    AAEX03016211    AADN05000047    JARO02001805    KPP74385.1    AEMK02000004    DQIR01095110    DQIR01246720    HDA50586.1    AMGL01101828    GDIQ01175723    JAK76002.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000076502    + More
UP000002358    UP000242457    UP000005203    UP000053825    UP000036403    UP000192223    UP000053097    UP000075809    UP000078542    UP000007755    UP000027135    UP000078540    UP000005205    UP000078492    UP000008237    UP000007266    UP000015103    UP000078541    UP000009046    UP000019118    UP000030742    UP000001593    UP000054359    UP000198287    UP000000437    UP000000305    UP000008672    UP000001646    UP000221080    UP000261600    UP000034805    UP000192224    UP000009136    UP000248480    UP000018468    UP000005215    UP000081671    UP000248482    UP000000715    UP000028990    UP000002254    UP000007646    UP000248481    UP000245340    UP000286640    UP000000539    UP000008227    UP000002356    UP000252040   

PRIDE

H9J3G7    Q8MJJ1   

Pfam

PF00561   Abhydrolase_1

Interpro

IPR019734   TPR_repeat        + More
IPR029058   AB_hydrolase       
IPR026151   Maspardin       
IPR011990   TPR-like_helical_dom_sf       
IPR000073   AB_hydrolase_1       

SUPFAM

SSF48452   SSF48452        + More
SSF53474   SSF53474       

Gene 3D

1.25.40.10     3.40.50.1820    

ProteinModelPortal

H9J3G7   A0A2A4JA43   A0A2W1BJX3   A0A023PTS0   A0A2H1VPK8   A0A194QWL0   + More
A0A194QQD3   A0A212EPN2   A0A154NXS6   K7IZF2   A0A2A3ERE4   A0A088AUM4   A0A0C9RN80   A0A0L7R7R7   A0A310SN11   A0A0J7KI73   A0A1W4X753   I4DKW8   A0A1Y1KNB7   A0A026VW30   A0A151X472   A0A195CNP6   F4WE58   V5I7Z6   A0A067RGW5   A0A151I5W9   A0A158NAN2   A0A151IYN0   A0A0T6AWI4   E2B4Y5   D6WQD6   A0A1Y1KJW9   A0A1B6GIW3   A0A1B6JK98   A0A1B6M629   A0A023F3Z1   A0A0K8RP44   A0A069DS48   A0A0V0G9A9   A0A224YUY1   A0A131Z339   L7LX54   T1IBN9   A0A131XEU9   A0A151JYJ7   A0A0A9YZX7   R4V3E9   A0A1E1XGI1   A0A023GBB4   A0A224XTV9   A0A1B6D4C4   A0A1B6CEJ9   E0VQU6   N6UAR4   A0A1W7RA91   A0A0P4WHT9   A7SGB1   A0A087UNC4   A0A1Z5KXD1   A0A293N5I5   T1JNR9   A0A226EVY6   F8W490   E9HMP4   F1QFZ2   H2ZSC3   H9G9D1   A0A2D0RV26   Q6PC62   K4FT91   J3SCL2   T1DKH7   A0A3Q3IVX3   A0A250YFE2   A0A0P7VTU9   L8IAZ0   Q8MJJ1   A0A098LXE7   A0A2Y9DHH4   A0A2D4FPI9   W5N9S1   A0A091KM28   A0A287D169   A0A1S3EMX4   U6CUR2   A0A2Y9KF64   M3XN72   A0A091DT71   A0A1W7RFZ6   E2QSZ2   G3SQV6   A0A2Y9HCU8   A0A2U3WKP8   A0A3Q7TPQ7   E1C0Z8   A0A0N8K1A4   F1S1X1   W5Q8G9   A0A0N8BI17   A0A341AM74  

PDB

3HZO     E-value=0.00337809,     Score=94

KEGG

101743343    K19367 maspardin | (RefSeq) maspardin-like

PATHWAY

04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0016787   GO:0030140   GO:0043231   GO:0042609   GO:0005829  

PANTHER

PTHR15913  

Subcellular location

Cytoplasm  

Length:

321

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.12469

Exp number, first 60 AAs:

0.01774

Total prob of N-in:

0.01810

outside

1  -  321

 

 

Pi

174.762488

Theta

161.6131

Tajima's D

0.50222

CLR

0.055047

CSRT

0.518074096295185

Interpretation

Uncertain