Gene

KWMTBOMO11506

Pre Gene Modal

BGIBMGA001910

Annotation

PREDICTED:_diuretic_hormone_receptor_[Bombyx_mori]

Location

Bomo_Chr19(+):7442455-7478213      View in EpiBrowser

Full name

Diuretic hormone receptor      

Location in the cell

PlasmaMembrane   Reliability : 4.967

CDS

ATGACGGGAAAGTACTCGGCATTGATCACATCATACATTACAAACATGCTAATTACGTTGTACGGGCAAGAAATGTTAAATGACACCGCCATAATTGAAGCAAAAACGAAAGTTCCTTGTACGATACGCAAATACTTCTGCAGACTGCCGATGTTTACTTTCGGAGCGTTATCACTTGATAAGTTAGAACACAAGCCGCGTGTAAACATTTTTATCATGTACATTTTTAACGGCAAACTGGAGGACTTACAGACTTTAGAAAGCGCAGAAAGCGTTATCGAAAATGCGACTGCAAGGACCGAGTGCTTGGCGAGGAACGCTAATCTCACAGAATACTACTGCCCGGCATATTTTGATGGATTGTTGTGTTGGAACCCGACGCCGAGCCACACGGTCGCCGTCCAGAAATGCTTTAAAGAATTTTTTGGAATAAAATACGATGAAACACAAAACGCTTCTCGTCTGTGTCTGGACGGTGTTTGGCAGAACTACACCGACTACTCGAATTGCACGGAGCGGATCGCTAATGTGTCACCCACGGACGTGGCCAGTCTCATATACTTGACGGGATACTCTCTCAGTCTCGCCGTTTTATCGCTGGCCGTCTTCGTCTTCTTGTATTTTAAGGATCTAAGATGCTTAAGAAACACGATACATACAAATTTAATGACCACATATATACTATCGGCTTGTAGTTGGATATTAAATTTAGCTTTACAAAATTGGTCCGACGAGGCACAGCAAGATCAAACGTCATGCATGATCTTAGTTATATGCATGCATTATTTTTATCTAACGAATTTCTTCTGGATGCTCGTTGAAGGTCTGTACCTGTACATGCTTGTTGTGGAAACATTCACCGCGGAAAATATTAAACTCAAAGTATACACTACCATCGGTTGGGGTGCTCCGGCGATATTCATCACAATTTGGGTCGTGTCAAGATGTTTTGTCAACGTCATGCCATCGACTGGACCAGACGGTCTTGCGCTTGCTGGGGAAGCGAAGATGTGTATATGGATGCACGAACATCAGGTGGACTGGATACACAAAGCTCCCGCGTTGGCGGGACTCGCGCTGAACTTATTTTTCCTTGTCAGGATTATGTGGGTGCTGATTACGAAACTCCGCTCGGCGAACACCCTCGAAACAGAACAATACAGGAAGGCTACTAAAGCGCTTCTTGTATTGATACCATTGTTGGGTATCACTAACTTGCTTGTGCTCTGCGGACCTAGTGACGACTCCTGGTTCGCGTACTCATTCGACTACGCGAGAGCCCTCATGCTATCAACACAGGGATTCACAGTGGCCCTATTCTATTGCTTCATGAACACTGAGGTGAGACACGCGATCAGGTACCACGTTGAGAGATGGAAGACTGGCAGAAATATCGGAGGAGGGAGAAGGAGGGGAGCTTCATACTCTAAGGACTGGTCTCCTAGATCCAGAACGGAGAGTATACGGTTATACAACCACCCGTCGAAGCGAGAGTCTGCGGCTTCGGAGACGACCACCACCACACTCCTCGTGCCGAGGACCTCACTCGCACCGCACTATGACTCCAGGCACCTACACGCTGACTACATCACGAGCGGTAGCGCTAGCGGGGAACAGTCTCCGGTTTGA

Protein

MTGKYSALITSYITNMLITLYGQEMLNDTAIIEAKTKVPCTIRKYFCRLPMFTFGALSLDKLEHKPRVNIFIMYIFNGKLEDLQTLESAESVIENATARTECLARNANLTEYYCPAYFDGLLCWNPTPSHTVAVQKCFKEFFGIKYDETQNASRLCLDGVWQNYTDYSNCTERIANVSPTDVASLIYLTGYSLSLAVLSLAVFVFLYFKDLRCLRNTIHTNLMTTYILSACSWILNLALQNWSDEAQQDQTSCMILVICMHYFYLTNFFWMLVEGLYLYMLVVETFTAENIKLKVYTTIGWGAPAIFITIWVVSRCFVNVMPSTGPDGLALAGEAKMCIWMHEHQVDWIHKAPALAGLALNLFFLVRIMWVLITKLRSANTLETEQYRKATKALLVLIPLLGITNLLVLCGPSDDSWFAYSFDYARALMLSTQGFTVALFYCFMNTEVRHAIRYHVERWKTGRNIGGGRRRGASYSKDWSPRSRTESIRLYNHPSKRESAASETTTTTLLVPRTSLAPHYDSRHLHADYITSGSASGEQSPV

Similarity

Belongs to the G-protein coupled receptor 2 family.

Keywords

Cell membrane   G-protein coupled receptor   Glycoprotein   Membrane   Receptor   Transducer   Transmembrane   Transmembrane helix   Signal  

Feature

chain  Diuretic hormone receptor

Uniprot

A0A194QXL6   A0A194QK26   P35464   A0A0S1YDC3   G3CKA8   B6VCU7   + More
B6VCU3   A0A1B6DBY6   Q65AS2   A0A1Y1KDD1   A0A139WBV2   A0A1Y1KJG5   Q65AS3   A0A1Y1KDE3   Q16983   A0A224XR65   A0A2U9PG90   B3FN73   B4F7L3   A0A1Q3FJD0   A0A1Q3FK63   A0A139WBU8   A0A1Q3FKA1   A0A1Q3FK13   A0A1Q3FK45   A0A182RFL3   A0A1Q3FK52   A0A2M4CI98   W5JKI3   A0A0A1WY41   A0A3B0J3W5   Q28X78   A0A2H8TNI8   A0A0R3NQ01   J9M7L7   A0A3B0JN39   A0A0R3NPR2   A0A0Q9W0T1   A0A1I8MWK2   A0A0M4ETT2   A0A182LYB7   A0A0Q9W896   A0A182Y0U9   A0A336LUX8   B3NRZ9   A0A2C9GPK6   Q7Q773   A0A0J9RAY4   B3MEN2   Q4V3E9   B4N601   B4HPJ8   B4QCX4   B4P592   A0A0Q9XG64   A0A034W5C9   A0A1W4UJB3   E0VEH3   A0A2M4CR10   A0A2M4CYV5   A0A0R1DW56   A0A084W2V1   A0A0K8UG33   B4J886   A0A1I8Q291   A0A1I8Q273   A0A3B0J0Z9   A0A1W4UHG8   A0A1I8MMV0   A0A0K8V0F2   A0A182UZ74   W8C899   A0A0L0C399   A0A0K0LFR2   A0A2C9GPP6   A0A034WB61   T1H976   A0A0K8U0V0   A0A0K8VM25   A0A0K8VJV2   A0A182FFC9   W8BFD2   A0A182Y0U8   A0A1B6CDW7   A0A182LJP0   A0A1B6GNH4   A0A182TZL7   A0A0Q5VMV0   A0A1B6IFI2  

Pubmed

26354079    8276884    22093064    15373805    28004739    18362917    + More
19820115    8673074    18651923    20920257    23761445    25830018    15632085    17994087    23185243    25315136    18057021    25244985    12364791    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25348373    20566863    24438588    24495485    26108605    20966253   

EMBL

KQ461073    KPJ09700.1    KQ458575    KPJ05729.1    U03489    KT031047    + More
ALM88345.1    HQ008729    AEK82133.1    FJ374694    ACJ06654.1    FJ374690    ACJ06650.1    GEDC01014104    JAS23194.1    AJ634781    CAG25576.1    GEZM01086343    GEZM01086341    JAV59532.1    KQ971372    KYB25406.1    GEZM01086338    GEZM01086336    JAV59536.1    AJ634780    CAG25575.2    GEZM01086342    GEZM01086340    JAV59533.1    U15959    GFTR01005925    JAW10501.1    MG550231    AWT50665.1    EU273352    ABX57920.1    BK006347    DAA06284.1    GFDL01007314    JAV27731.1    GFDL01007162    JAV27883.1    KYB25407.1    GFDL01007132    JAV27913.1    GFDL01007136    JAV27909.1    GFDL01007172    JAV27873.1    GFDL01007173    JAV27872.1    GGFL01000791    MBW64969.1    ADMH02000928    ETN64646.1    GBXI01011004    JAD03288.1    OUUW01000001    SPP74053.1    CM000071    EAL26438.2    GFXV01003765    MBW15570.1    KRT03106.1    ABLF02041105    ABLF02041114    ABLF02041126    ABLF02041133    ABLF02041157    SPP74051.1    KRT03100.1    KRT03102.1    KRT03104.1    CH940662    KRF78422.1    CP012524    ALC40695.1    AXCM01005703    AXCM01005704    KRF78420.1    KRF78421.1    KRF78423.1    KRF78424.1    KRF78425.1    KRF78426.1    KRF78427.1    UFQS01000007    UFQT01000007    SSW97072.1    SSX17458.1    CH954179    EDV56301.1    APCN01004347    APCN01004348    APCN01004349    AAAB01008960    EAA11768.4    CM002911    KMY93223.1    CH902619    EDV35496.2    KPU75698.1    KPU75699.1    KPU75701.1    AE013599    BT023407    AAF58501.4    AAY55823.1    CH964154    EDW79790.2    CH480816    EDW47582.1    CM000362    EDX06785.1    KMY93218.1    CM000158    EDW90754.1    CH933808    KRG03906.1    GAKP01009019    GAKP01009018    JAC49934.1    DS235090    EEB11779.1    GGFL01003150    MBW67328.1    GGFL01006281    MBW70459.1    KRJ99447.1    KRJ99448.1    KRJ99449.1    ATLV01019701    ATLV01019702    ATLV01019703    KE525278    KFB44545.1    GDHF01026677    GDHF01026131    JAI25637.1    JAI26183.1    CH916367    EDW01223.1    SPP74744.1    GDHF01019930    JAI32384.1    GAMC01007611    JAB98944.1    JRES01000960    KNC26741.1    KJ407397    AJA04995.1    APCN01004353    GAKP01006161    JAC52791.1    ACPB03016148    ACPB03016149    GDHF01031987    JAI20327.1    GDHF01012704    JAI39610.1    GDHF01013150    JAI39164.1    GAMC01010907    JAB95648.1    GEDC01025652    JAS11646.1    GECZ01005773    JAS63996.1    KQS62832.1    GECU01028762    GECU01022031    JAS78944.1    JAS85675.1   

Proteomes

UP000053240    UP000053268    UP000007266    UP000075900    UP000000673    UP000268350    + More
UP000001819    UP000007819    UP000008792    UP000095301    UP000092553    UP000075883    UP000076408    UP000008711    UP000075840    UP000007062    UP000007801    UP000000803    UP000007798    UP000001292    UP000000304    UP000002282    UP000009192    UP000192221    UP000009046    UP000030765    UP000001070    UP000095300    UP000075903    UP000037069    UP000015103    UP000069272    UP000075882    UP000075902   

PRIDE

Q4V3E9   

Pfam

PF00002   7tm_2        + More
PF02793   HRM

Interpro

IPR002001   GPCR_2_diuretic_rcpt        + More
IPR000832   GPCR_2_secretin-like       
IPR001879   GPCR_2_extracellular_dom       
IPR017981   GPCR_2-like       
IPR036445   GPCR_2_extracell_dom_sf       
IPR017983   GPCR_2_secretin-like_CS       
IPR018247   EF_Hand_1_Ca_BS       

SUPFAM

SSF111418   SSF111418       

Gene 3D

4.10.1240.10    

CDD

cd15263  7tmB1_DH_R

ProteinModelPortal

A0A194QXL6   A0A194QK26   P35464   A0A0S1YDC3   G3CKA8   B6VCU7   + More
B6VCU3   A0A1B6DBY6   Q65AS2   A0A1Y1KDD1   A0A139WBV2   A0A1Y1KJG5   Q65AS3   A0A1Y1KDE3   Q16983   A0A224XR65   A0A2U9PG90   B3FN73   B4F7L3   A0A1Q3FJD0   A0A1Q3FK63   A0A139WBU8   A0A1Q3FKA1   A0A1Q3FK13   A0A1Q3FK45   A0A182RFL3   A0A1Q3FK52   A0A2M4CI98   W5JKI3   A0A0A1WY41   A0A3B0J3W5   Q28X78   A0A2H8TNI8   A0A0R3NQ01   J9M7L7   A0A3B0JN39   A0A0R3NPR2   A0A0Q9W0T1   A0A1I8MWK2   A0A0M4ETT2   A0A182LYB7   A0A0Q9W896   A0A182Y0U9   A0A336LUX8   B3NRZ9   A0A2C9GPK6   Q7Q773   A0A0J9RAY4   B3MEN2   Q4V3E9   B4N601   B4HPJ8   B4QCX4   B4P592   A0A0Q9XG64   A0A034W5C9   A0A1W4UJB3   E0VEH3   A0A2M4CR10   A0A2M4CYV5   A0A0R1DW56   A0A084W2V1   A0A0K8UG33   B4J886   A0A1I8Q291   A0A1I8Q273   A0A3B0J0Z9   A0A1W4UHG8   A0A1I8MMV0   A0A0K8V0F2   A0A182UZ74   W8C899   A0A0L0C399   A0A0K0LFR2   A0A2C9GPP6   A0A034WB61   T1H976   A0A0K8U0V0   A0A0K8VM25   A0A0K8VJV2   A0A182FFC9   W8BFD2   A0A182Y0U8   A0A1B6CDW7   A0A182LJP0   A0A1B6GNH4   A0A182TZL7   A0A0Q5VMV0   A0A1B6IFI2  

PDB

5UZ7     E-value=2.04163e-32,     Score=349

KEGG

101743146    K04578 corticotropin releasing hormone receptor 1 | (RefSeq) diuretic hormone receptor

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0007166   GO:0016021   GO:0008036   GO:0004930   GO:0005886   GO:0017046   GO:0005887   GO:0009651   GO:0007186   GO:0009755   GO:0004948   GO:0008188   GO:0016020   GO:0004888   GO:0003707   GO:0006418   GO:0003824  

Subcellular location

Cell membrane  

Length:

542

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

153.30553

Exp number, first 60 AAs:

4.91283

Total prob of N-in:

0.28096

outside

1  -  183

TMhelix

184  -  206

inside

207  -  217

TMhelix

218  -  240

outside

241  -  259

TMhelix

260  -  282

inside

283  -  294

TMhelix

295  -  314

outside

315  -  353

TMhelix

354  -  373

inside

374  -  392

TMhelix

393  -  412

outside

413  -  421

TMhelix

422  -  444

inside

445  -  542

 

 

Pi

201.107883

Theta

172.531651

Tajima's D

0.794386

CLR

0.164627

CSRT

0.603769811509425

Interpretation

Uncertain