Gene

KWMTBOMO11498

Pre Gene Modal

BGIBMGA001907

Annotation

Proton-coupled_folate_transporter_[Papilio_xuthus]

Location

Bomo_Chr19(+):7150451-7163141      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 4.95

CDS

ATGAACGAGAAACCAGGAAGTGTAACTGAAATGACCGAAGTGAGTAAAGAGAATTCGGAAAACAATGAACAGATTGAGAATAAAGAAACACCGAATACTCGGAAGTGGTCGATTTCGTCATCGTTGAATGCAATACTAAATTTCTTCGCGTATCTCACGGTGGAGCCGTTCATGATTTGTTACATTTTACCAAGTGCCATATCGGGATTAGCGGTCCAAAGATTGAATATAGAGAAAGCCTGCCGGAGCGACCTTAATTATTCCGATGCTATATGTCTTCTCGTAAGGAACGGCGATGCAGAAGACAATATAACTATAGAGGCACAAATAACTACAAGCAAAATCGTTTCGGACATGACAGCGTGGCAATATCCTGTGCAGAACAGCATACCGACTATAATCATTTTATTCGTTGGAGCTTGGAGCGACCGGACTGGAAATAGAAAAGCGTTAATGTTGATCCCGCTGATAGGTGAAATAATATCGTCATTCGGATTGATTCTGACCACTTACTTTTTCTTGGAATGGCCTTTATGGGCCACAGCACTGATAGAGGCATTACCTTCGGCTCTGAGCGGTGGATCGTCCATTGCCTTTATGGGCTCATACAGTTATATCGCTGATGTAACGACTCTCGAATCTCGTACGTTCCGAATTGGATTCGTGGCTGTAATAGTATCTCTCGTATTACCTTTTGGGATTTCTATAAGCGGAGTTTTGACGGAAGCTGTCGGCTATTATGGAGTTTTCGGCCTCAATATGATCCTGTACATACTTGGTTTTATTCATACATACTTTCGTGTGCATAACGTTAGGAATCAAAGCGTTGAAGGAAATCTGATTAATAAAATTATCGACTTCTTTCATCCTAGAAACGCATGGGATAGCATTTCTATAATGTTTTTAACACCCTTGAAGCAAAGGATACAAACGATTTTAGTTCTGTGGGCGCATATCGTCATACTTGGACCTGTTATAGGCGAACTCTCCGTACTCACGTTATACGCATTGAACAAATTCAGCATGAACGTTGTTGACTTGAGTTTGTTCATTACGTACTCTACACTGATGGGAACGGCAGGGACTTTATTGGCTGTGACACTCTTTAGTAAGCACTTGAAAATGCACGATGCCTTATTAGGAATCATAGCGGCGACATGCCAGACTGTCTCCAGTATCGTTTACGCATTAGCACCGACAAAGGCTTGGTTATTCTCCGGTCCAGTTTTTAATTTATTTGGAACAACCGGGGTGACGGCAACAAGGTCGTTGGGTACTAAAGTCGTGGACCCGGATAAAGTAGGTAAAATCTGCTCCCTCCTTGGATTAGCCGAGTCTCTTGTACTGATCATTTACACGCCTATATACAGCAAGCTTTTTACTAACACGGTGACCACACTACCAGGTGCAGTTTACTTTTTGGGCGCAGCAATGACAGTCCCAGCTTTCTTTCTATTCGGAACCCTCTACAAAATCAACAAAAAACAGGAGCGTGACGTTGTCCAAAACCCAGAACTGAAGGAAATGCATGCCCACGATAATCAAATAGCAACACCTTAA

Protein

MNEKPGSVTEMTEVSKENSENNEQIENKETPNTRKWSISSSLNAILNFFAYLTVEPFMICYILPSAISGLAVQRLNIEKACRSDLNYSDAICLLVRNGDAEDNITIEAQITTSKIVSDMTAWQYPVQNSIPTIIILFVGAWSDRTGNRKALMLIPLIGEIISSFGLILTTYFFLEWPLWATALIEALPSALSGGSSIAFMGSYSYIADVTTLESRTFRIGFVAVIVSLVLPFGISISGVLTEAVGYYGVFGLNMILYILGFIHTYFRVHNVRNQSVEGNLINKIIDFFHPRNAWDSISIMFLTPLKQRIQTILVLWAHIVILGPVIGELSVLTLYALNKFSMNVVDLSLFITYSTLMGTAGTLLAVTLFSKHLKMHDALLGIIAATCQTVSSIVYALAPTKAWLFSGPVFNLFGTTGVTATRSLGTKVVDPDKVGKICSLLGLAESLVLIIYTPIYSKLFTNTVTTLPGAVYFLGAAMTVPAFFLFGTLYKINKKQERDVVQNPELKEMHAHDNQIATP

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Uniprot

A0A2A4JF01   A0A2H1VB80   A0A194QJM1   A0A194QW49   A0A3S2N9Z1   A0A194QVZ2   + More
A0A194QQC6   Q16W79   A0A194QAI0   A0A194RE89   A0A1Q3FLC7   A0A1Q3FLB8   B0WAI1   A0A194PXP8   A0A182J2E5   A0A1Y1KH29   A0A194R1H5   A0A212FAK5   A0A2M4AAV7   Q5TSW5   A0A182MSS2   A0A194QJI0   A0A2C9H8S5   A0A182VHT3   I4DPC5   A0A2H1W938   A0A2M4BIX1   A0A2M4BIV5   A0A2M3Z363   A0A2M3Z330   A0A2M4CTY3   A0A2M4CUE3   A0A2M4CSN5   A0A2M4CUE7   A0A182QCE8   H9JAJ5   A0A2H1VB83   A0A194REM1   A0A1B6LYH9   A0A2W1BZD6   A0A146M6W4   A0A3S2LGU6   A0A2A4IY18   A0A0A9W4N6   A0A023F1I8   A0A1W4WW74   A0A212FAJ8   A0A1B6CY04   A0A2H8TM94   A0A3S2PBF1   A0A1L8DDP9   A0A1I8M3Q0   A0A1J1HPT6   A0A067RJA9   J9KB87   A0A146LMI6   D2A535   A0A2A4JFG5   A0A212F197   A0A1I8PUY1   A0A182RDY9   U4URR0   A0A182PQS5   A0A084WT83   W8C3P0   A0A182N9U1   A0A2S2PEA7   A0A2H8TQH7   A0A1B6HTG8   A0A069DVE7   A0A182W3L5   A0A023F3V3   A0A0L7L750   E9IUT7   A0A0L0C7Q4   E2A659   A0A034W601   D6WRR1   A0A195F6C4   A0A0K8WKB4   A0A026WMI6   A0A195CVZ7   A0A0L7RGJ1   A0A151ITA2   A0A151WHP4   X1WII3   F4WT02   A0A158NYI1   A0A1Y1M9T2   A0A195AZB4   A0A0A1XR69   B4NPQ3   A0A212F1A9   Q6NPA2   Q9VY22   A0A2S2R688   A0A182F8Z6  

EC Number

3.4.-.-

Pubmed

26354079    17510324    28004739    22118469    12364791    14747013    + More
17210077    22651552    19121390    28756777    26823975    25401762    25474469    25315136    24845553    18362917    19820115    23537049    24438588    24495485    26334808    26227816    21282665    26108605    20798317    25348373    24508170    30249741    21719571    21347285    25830018    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

NWSH01001779    PCG70164.1    ODYU01001620    SOQ38099.1    KQ458575    KPJ05727.1    + More
KQ461073    KPJ09702.1    RSAL01000373    RVE42131.1    KPJ09703.1    KPJ05726.1    CH477573    EAT38831.1    KQ459249    KPJ02439.1    KQ460323    KPJ15907.1    GFDL01006731    JAV28314.1    GFDL01006678    JAV28367.1    DS231872    EDS41404.1    KQ459586    KPI98097.1    GEZM01088643    GEZM01088642    JAV58047.1    KPJ09701.1    AGBW02009461    OWR50760.1    GGFK01004578    MBW37899.1    AAAB01008898    EAL40562.4    AXCM01000458    KPJ05728.1    AK403525    BAM19765.1    ODYU01007104    SOQ49580.1    GGFJ01003792    MBW52933.1    GGFJ01003793    MBW52934.1    GGFM01002194    MBW22945.1    GGFM01002176    MBW22927.1    GGFL01004110    MBW68288.1    GGFL01004788    MBW68966.1    GGFL01004111    MBW68289.1    GGFL01004789    MBW68967.1    AXCN02001200    BABH01009475    BABH01009476    BABH01009477    SOQ38098.1    KPJ15909.1    GEBQ01011235    JAT28742.1    KZ149899    PZC78617.1    GDHC01003145    JAQ15484.1    RSAL01000011    RVE53552.1    NWSH01004603    PCG64857.1    GBHO01041233    GBRD01004096    JAG02371.1    JAG61725.1    GBBI01003382    JAC15330.1    OWR50762.1    GEDC01018946    GEDC01008979    JAS18352.1    JAS28319.1    GFXV01003482    MBW15287.1    RSAL01000124    RVE46608.1    GFDF01009508    JAV04576.1    CVRI01000006    CRK88225.1    KK852651    KDR19441.1    ABLF02035671    GDHC01010234    JAQ08395.1    KQ971361    EFA05308.1    PCG70163.1    AGBW02010938    OWR47491.1    KB632410    ERL95208.1    ATLV01026865    ATLV01026866    KE525420    KFB53427.1    GAMC01005989    JAC00567.1    GGMR01015172    MBY27791.1    GFXV01004631    MBW16436.1    GECU01029729    JAS77977.1    GBGD01001034    JAC87855.1    GBBI01002626    JAC16086.1    JTDY01002581    KOB71159.1    GL766050    EFZ15659.1    JRES01000902    KNC27439.1    GL437108    EFN71118.1    GAKP01009377    JAC49575.1    KQ971354    EFA05964.2    KQ981768    KYN35936.1    GDHF01032155    GDHF01019937    GDHF01013697    GDHF01000723    JAI20159.1    JAI32377.1    JAI38617.1    JAI51591.1    KK107151    QOIP01000003    EZA57287.1    RLU24717.1    KQ977220    KYN04851.1    KQ414596    KOC69980.1    KQ981029    KYN10190.1    KQ983114    KYQ47337.1    ABLF02035661    GL888331    EGI62615.1    ADTU01003883    GEZM01038156    JAV81758.1    KQ976701    KYM77299.1    GBXI01016992    GBXI01013508    GBXI01006853    GBXI01003332    GBXI01000927    JAC97299.1    JAD00784.1    JAD07439.1    JAD10960.1    JAD13365.1    CH964291    EDW86493.1    OWR47493.1    BT011024    AAR30184.1    AE014298    BT133123    AAF48383.1    AEY64291.1    GGMS01016275    MBY85478.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000283053    UP000008820    UP000002320    + More
UP000075880    UP000007151    UP000007062    UP000075883    UP000076407    UP000075903    UP000075886    UP000005204    UP000192223    UP000095301    UP000183832    UP000027135    UP000007819    UP000007266    UP000095300    UP000075900    UP000030742    UP000075885    UP000030765    UP000075884    UP000075920    UP000037510    UP000037069    UP000000311    UP000078541    UP000053097    UP000279307    UP000078542    UP000053825    UP000078492    UP000075809    UP000007755    UP000005205    UP000078540    UP000007798    UP000000803    UP000069272   

PRIDE

H9JAJ5    Q6NPA2    Q9VY22   

Pfam

PF07690   MFS_1        + More
PF01401   Peptidase_M2
PF07701   HNOBA
PF00211   Guanylate_cyc
PF07700   HNOB

Interpro

IPR036259   MFS_trans_sf        + More
IPR011701   MFS       
IPR020846   MFS_dom       
IPR001548   Peptidase_M2       
IPR018297   A/G_cyclase_CS       
IPR038158   H-NOX_domain_sf       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR011645   HNOB_dom_associated       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR011644   Heme_NO-bd       

SUPFAM

SSF103473   SSF103473        + More
SSF55073   SSF55073       
SSF111126   SSF111126       

Gene 3D

3.30.70.1230     3.90.1520.10    

CDD

cd06174  MFS
cd06461  M2_ACE

ProteinModelPortal

A0A2A4JF01   A0A2H1VB80   A0A194QJM1   A0A194QW49   A0A3S2N9Z1   A0A194QVZ2   + More
A0A194QQC6   Q16W79   A0A194QAI0   A0A194RE89   A0A1Q3FLC7   A0A1Q3FLB8   B0WAI1   A0A194PXP8   A0A182J2E5   A0A1Y1KH29   A0A194R1H5   A0A212FAK5   A0A2M4AAV7   Q5TSW5   A0A182MSS2   A0A194QJI0   A0A2C9H8S5   A0A182VHT3   I4DPC5   A0A2H1W938   A0A2M4BIX1   A0A2M4BIV5   A0A2M3Z363   A0A2M3Z330   A0A2M4CTY3   A0A2M4CUE3   A0A2M4CSN5   A0A2M4CUE7   A0A182QCE8   H9JAJ5   A0A2H1VB83   A0A194REM1   A0A1B6LYH9   A0A2W1BZD6   A0A146M6W4   A0A3S2LGU6   A0A2A4IY18   A0A0A9W4N6   A0A023F1I8   A0A1W4WW74   A0A212FAJ8   A0A1B6CY04   A0A2H8TM94   A0A3S2PBF1   A0A1L8DDP9   A0A1I8M3Q0   A0A1J1HPT6   A0A067RJA9   J9KB87   A0A146LMI6   D2A535   A0A2A4JFG5   A0A212F197   A0A1I8PUY1   A0A182RDY9   U4URR0   A0A182PQS5   A0A084WT83   W8C3P0   A0A182N9U1   A0A2S2PEA7   A0A2H8TQH7   A0A1B6HTG8   A0A069DVE7   A0A182W3L5   A0A023F3V3   A0A0L7L750   E9IUT7   A0A0L0C7Q4   E2A659   A0A034W601   D6WRR1   A0A195F6C4   A0A0K8WKB4   A0A026WMI6   A0A195CVZ7   A0A0L7RGJ1   A0A151ITA2   A0A151WHP4   X1WII3   F4WT02   A0A158NYI1   A0A1Y1M9T2   A0A195AZB4   A0A0A1XR69   B4NPQ3   A0A212F1A9   Q6NPA2   Q9VY22   A0A2S2R688   A0A182F8Z6  

KEGG

101741841    K20840 MFS transporter, PCFT/HCP family, solute carrier family 46, member 3 | (RefSeq) proton-couple

GO

GO:0016021   GO:0055085   GO:0004180   GO:0008237   GO:0008241   GO:0046872   GO:0020037   GO:0000166   GO:0035556   GO:0004383   GO:0031012   GO:0008233   GO:0004298   GO:0005839   GO:0051603   GO:0016740   GO:0003707   GO:0006418   GO:0003824  

PANTHER

PTHR10514  

Length:

519

Number of predicted TMHs:

11

Exp number of AAs in TMHs:

250.37101

Exp number, first 60 AAs:

14.22007

Total prob of N-in:

0.49269

POSSIBLE N-term signal

sequence

outside

1  -  49

TMhelix

50  -  72

inside

73  -  150

TMhelix

151  -  173

outside

174  -  182

TMhelix

183  -  205

inside

206  -  216

TMhelix

217  -  239

outside

240  -  243

TMhelix

244  -  266

inside

267  -  314

TMhelix

315  -  337

outside

338  -  346

TMhelix

347  -  369

inside

370  -  375

TMhelix

376  -  398

outside

399  -  401

TMhelix

402  -  424

inside

425  -  436

TMhelix

437  -  456

outside

457  -  470

TMhelix

471  -  490

inside

491  -  519

 

 

Pi

235.429346

Theta

178.404516

Tajima's D

0.736638

CLR

0.422255

CSRT

0.581620918954052

Interpretation

Uncertain