Gene

KWMTBOMO11497

Pre Gene Modal

BGIBMGA001911

Annotation

PREDICTED:_proton-coupled_folate_transporter-like_[Amyelois_transitella]

Location

Bomo_Chr19(-):7109441-7142100      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 4.953

CDS

ATGACGCTGCGGGTCGAAGTGCCCGGCGAAAAAGTTGTTAGTGTCGAACCCTGCAAGTGCAATAAACAATACAGTAAAGAAATCAACACCGAAAATAAACTTTCGCGCGATTTAAAGGAATCTCTAAAGAAAATATGGCGGTTGCGAACGAAAATCACCGTCGAACCGTTTGTGATATGTTACGTATTACCGAGTGTGCTAGCCGGGCTGGCGGTTCAAAATATGTGCCTCGAAAAATCGTGCCTAGTGAACCTGCAGTACGACGAGGAAACTTGCAGGCATATAATGCAAGGACGCACTCAGAACTACACAGAACAAGAAAAAAAAGTTCAAAGAATGGTCACTACGATGAGTAGTTGGAGTTCACCCCTGCAAACGGCACCGCCAGGCATCCTAGCCCTTTTTATAGGGGCCTGGAGCGACCGCACAGGCAACAGAAAGGCCTTCATGATCGTGCCTATTCTCGGAAAATTAATATCTGCGATCGGCGTCATGTTGAGTGCGGTATTCTTCCGGCAAGTCGGTATGAATGAGACTGCACTTCTGGAAGGTCTCTTGCCTGCACTGGCTGGTGGCCGCGTTGCCATGACGATGGCGGTTTATAGTTATATCTCTGATATCACAAGTGAATCAGAAAGGACTTTTCGTATAGGGATAGTAACTGCCGTATTGACACTGAGCAAGCCCGTCGGTCTTGCTCTAAGCGGGATAATGACAAGCAACTTCGGTTACAAGGCGGTTTTCGTGACCGCTTGCTTCATTTACATGTTCGGCTTCATTTATATTCTGTTGAGAATAAAAGAGAAAAAGAAGAAAACAGTTGACGGTACGAAGCTTGAGTGTGTATCTTTGTTTTCATTGTCAGACCTCGTAGCAACGGTAAAAGTGGGCTTTAAAGCGAGAGAGGGAACCCACCGCGTACAAGTCATCTTAATATTAATTTGTTACATGCTCATCGTTGGACCGCTATTAGGTGAAGCGCAGCTGACAATGTTGTTCACTCGATACAAGCACAAATTCACGGACATCGACTACAGTTTGTTCCTCGCATACTCCGTCTTTGTTGGGATTATCGGTTCCTTCATAACAATATACTTGTTCAGCAAAAGATGGAAGTTCGAGGACAGTATGATTGGAGTGATCGCGTGCTTCAGCAGAATCCTCGCGAGTATTGTCTACGCGGTGGCCCCGAACAGGACCGTTTACTTCCTTGGACCGGTCCTGGACATGTTCAGTTCAGCCGGTGCAACTTCCCTGAGGTCGCTCGCTTCTAAGCTAGTCGATTCTGATGAAGTTGGTAAAACGAGCTCTCTAATCAGCATATCAGAGGCGCTAGTTCCTGTGATCTACTCTCCGTTGTACGGATACGTGTATAAAAAGACCATGAGTACGTACTCTGGTGGTTTTTACCTGATCAGCACCGCGCTAGCTCTGCCCGCAACTGTGATACTAATAATTCTGTACGTCTTGCGCTCGAAGGAAGCGAGAGAGGCCAAAAGAAAACAGGAAACGAAGAAAGAAAGTGAGATTACCCGTTTTTGA

Protein

MTLRVEVPGEKVVSVEPCKCNKQYSKEINTENKLSRDLKESLKKIWRLRTKITVEPFVICYVLPSVLAGLAVQNMCLEKSCLVNLQYDEETCRHIMQGRTQNYTEQEKKVQRMVTTMSSWSSPLQTAPPGILALFIGAWSDRTGNRKAFMIVPILGKLISAIGVMLSAVFFRQVGMNETALLEGLLPALAGGRVAMTMAVYSYISDITSESERTFRIGIVTAVLTLSKPVGLALSGIMTSNFGYKAVFVTACFIYMFGFIYILLRIKEKKKKTVDGTKLECVSLFSLSDLVATVKVGFKAREGTHRVQVILILICYMLIVGPLLGEAQLTMLFTRYKHKFTDIDYSLFLAYSVFVGIIGSFITIYLFSKRWKFEDSMIGVIACFSRILASIVYAVAPNRTVYFLGPVLDMFSSAGATSLRSLASKLVDSDEVGKTSSLISISEALVPVIYSPLYGYVYKKTMSTYSGGFYLISTALALPATVILIILYVLRSKEAREAKRKQETKKESEITRF

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Uniprot

A0A194QVZ2   A0A194QQC6   A0A212F197   A0A0L7L6U1   A0A0L7KU43   S4PBU9   + More
A0A182QCE8   A0A194QW49   A0A194QJM1   A0A182J2E5   A0A2M4BIX1   A0A2M4BIV5   Q5TSW5   A0A2C9H8S5   A0A2M3Z363   A0A1J1HPT6   A0A2M3Z330   A0A2M4CUE3   A0A182MSS2   A0A2M4CTY3   A0A2M4CUE7   A0A2M4CSN5   A0A2M4AAV7   A0A182VHT3   Q16W79   A0A3S2N9Z1   A0A1Q3FLB8   B0WAI1   A0A1Q3FLC7   A0A1W4WW74   A0A067RJA9   A0A2W1BZD6   A0A023F1I8   A0A2H1W938   A0A1Y1KH29   A0A182N9U1   A0A182PQS5   A0A084WT83   A0A146LMI6   A0A0L0C7Q4   A0A182W3L5   A0A182RDY9   A0A3S2LGU6   A0A2A4JF01   J9KB87   A0A1B6CY04   A0A2H1WJM3   A0A194QAI0   A0A194PXP8   A0A194QJI0   W8C3P0   A0A194R1H5   I4DPC5   A0A194RE89   A0A1L8DDP9   A0A2H1VB80   D2A535   U4URR0   A0A3S2PBF1   A0A212FAK5   A0A1I8M3Q0   H9JAJ5   A0A2H8TM94   B3N1F7   A0A1I8PUY1   A0A212EU39   B4M2P7   A0A0M4FAI8   A0A182F8Z6   A0A2A4IY18   B4GY42   Q29H91   B3NUZ2   A0A146M6W4   A0A0L7RGJ1   D6WRR1   A0A3B0K378   A0A0A9W4N6   A0A154PAY0   Q6NPA2   A0A1A9WCM0   B4PW63   B4L4F7   A0A1W4VHL4   Q9VY22   B4R4V6   E9IUT7   A0A026WMI6   B4JJN3   A0A034W601   B4NPQ3   A0A194Q3W9   A0A0A1XR69   J9KB15   A0A194REM1   A0A1B0ANC8   A0A1A9XH14  

EC Number

3.4.-.-

Pubmed

26354079    22118469    26227816    23622113    12364791    14747013    + More
17210077    17510324    24845553    28756777    25474469    28004739    24438588    26823975    26108605    24495485    22651552    18362917    19820115    23537049    25315136    19121390    17994087    15632085    25401762    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    21282665    24508170    30249741    25348373    25830018   

EMBL

KQ461073    KPJ09703.1    KQ458575    KPJ05726.1    AGBW02010938    OWR47491.1    + More
JTDY01002578    KOB71162.1    JTDY01005650    KOB66783.1    GAIX01002674    JAA89886.1    AXCN02001200    KPJ09702.1    KPJ05727.1    GGFJ01003792    MBW52933.1    GGFJ01003793    MBW52934.1    AAAB01008898    EAL40562.4    GGFM01002194    MBW22945.1    CVRI01000006    CRK88225.1    GGFM01002176    MBW22927.1    GGFL01004788    MBW68966.1    AXCM01000458    GGFL01004110    MBW68288.1    GGFL01004789    MBW68967.1    GGFL01004111    MBW68289.1    GGFK01004578    MBW37899.1    CH477573    EAT38831.1    RSAL01000373    RVE42131.1    GFDL01006678    JAV28367.1    DS231872    EDS41404.1    GFDL01006731    JAV28314.1    KK852651    KDR19441.1    KZ149899    PZC78617.1    GBBI01003382    JAC15330.1    ODYU01007104    SOQ49580.1    GEZM01088643    GEZM01088642    JAV58047.1    ATLV01026865    ATLV01026866    KE525420    KFB53427.1    GDHC01010234    JAQ08395.1    JRES01000902    KNC27439.1    RSAL01000011    RVE53552.1    NWSH01001779    PCG70164.1    ABLF02035671    GEDC01018946    GEDC01008979    JAS18352.1    JAS28319.1    ODYU01009084    SOQ53249.1    KQ459249    KPJ02439.1    KQ459586    KPI98097.1    KPJ05728.1    GAMC01005989    JAC00567.1    KPJ09701.1    AK403525    BAM19765.1    KQ460323    KPJ15907.1    GFDF01009508    JAV04576.1    ODYU01001620    SOQ38099.1    KQ971361    EFA05308.1    KB632410    ERL95208.1    RSAL01000124    RVE46608.1    AGBW02009461    OWR50760.1    BABH01009475    BABH01009476    BABH01009477    GFXV01003482    MBW15287.1    CH902654    EDV33596.1    AGBW02012463    OWR45015.1    CH940651    EDW65951.1    CP012528    ALC49420.1    NWSH01004603    PCG64857.1    CH479196    EDW27669.1    CH379064    EAL31867.2    CH954180    EDV47090.1    GDHC01003145    JAQ15484.1    KQ414596    KOC69980.1    KQ971354    EFA05964.2    OUUW01000015    SPP88717.1    GBHO01041233    GBRD01004096    JAG02371.1    JAG61725.1    KQ434864    KZC08967.1    BT011024    AAR30184.1    CM000162    EDX01694.1    KRK06299.1    CH933810    EDW07435.1    AE014298    BT133123    AAF48383.1    AEY64291.1    CM000366    EDX17913.1    GL766050    EFZ15659.1    KK107151    QOIP01000003    EZA57287.1    RLU24717.1    CH916370    EDV99785.1    GAKP01009377    JAC49575.1    CH964291    EDW86493.1    KPI98100.1    GBXI01016992    GBXI01013508    GBXI01006853    GBXI01003332    GBXI01000927    JAC97299.1    JAD00784.1    JAD07439.1    JAD10960.1    JAD13365.1    ABLF02027891    ABLF02027892    KPJ15909.1    JXJN01000793   

Proteomes

UP000053240    UP000053268    UP000007151    UP000037510    UP000075886    UP000075880    + More
UP000007062    UP000076407    UP000183832    UP000075883    UP000075903    UP000008820    UP000283053    UP000002320    UP000192223    UP000027135    UP000075884    UP000075885    UP000030765    UP000037069    UP000075920    UP000075900    UP000218220    UP000007819    UP000007266    UP000030742    UP000095301    UP000005204    UP000007801    UP000095300    UP000008792    UP000092553    UP000069272    UP000008744    UP000001819    UP000008711    UP000053825    UP000268350    UP000076502    UP000091820    UP000002282    UP000009192    UP000192221    UP000000803    UP000000304    UP000053097    UP000279307    UP000001070    UP000007798    UP000092460    UP000092443   

PRIDE

H9JAJ5    Q6NPA2    Q9VY22   

Pfam

PF07690   MFS_1        + More
PF01401   Peptidase_M2
PF07701   HNOBA
PF00211   Guanylate_cyc
PF07700   HNOB

Interpro

IPR020846   MFS_dom        + More
IPR036259   MFS_trans_sf       
IPR011701   MFS       
IPR001548   Peptidase_M2       
IPR018297   A/G_cyclase_CS       
IPR038158   H-NOX_domain_sf       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR011645   HNOB_dom_associated       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR011644   Heme_NO-bd       

SUPFAM

SSF103473   SSF103473        + More
SSF55073   SSF55073       
SSF111126   SSF111126       

Gene 3D

3.30.70.1230     3.90.1520.10    

CDD

cd06174  MFS
cd06461  M2_ACE

ProteinModelPortal

A0A194QVZ2   A0A194QQC6   A0A212F197   A0A0L7L6U1   A0A0L7KU43   S4PBU9   + More
A0A182QCE8   A0A194QW49   A0A194QJM1   A0A182J2E5   A0A2M4BIX1   A0A2M4BIV5   Q5TSW5   A0A2C9H8S5   A0A2M3Z363   A0A1J1HPT6   A0A2M3Z330   A0A2M4CUE3   A0A182MSS2   A0A2M4CTY3   A0A2M4CUE7   A0A2M4CSN5   A0A2M4AAV7   A0A182VHT3   Q16W79   A0A3S2N9Z1   A0A1Q3FLB8   B0WAI1   A0A1Q3FLC7   A0A1W4WW74   A0A067RJA9   A0A2W1BZD6   A0A023F1I8   A0A2H1W938   A0A1Y1KH29   A0A182N9U1   A0A182PQS5   A0A084WT83   A0A146LMI6   A0A0L0C7Q4   A0A182W3L5   A0A182RDY9   A0A3S2LGU6   A0A2A4JF01   J9KB87   A0A1B6CY04   A0A2H1WJM3   A0A194QAI0   A0A194PXP8   A0A194QJI0   W8C3P0   A0A194R1H5   I4DPC5   A0A194RE89   A0A1L8DDP9   A0A2H1VB80   D2A535   U4URR0   A0A3S2PBF1   A0A212FAK5   A0A1I8M3Q0   H9JAJ5   A0A2H8TM94   B3N1F7   A0A1I8PUY1   A0A212EU39   B4M2P7   A0A0M4FAI8   A0A182F8Z6   A0A2A4IY18   B4GY42   Q29H91   B3NUZ2   A0A146M6W4   A0A0L7RGJ1   D6WRR1   A0A3B0K378   A0A0A9W4N6   A0A154PAY0   Q6NPA2   A0A1A9WCM0   B4PW63   B4L4F7   A0A1W4VHL4   Q9VY22   B4R4V6   E9IUT7   A0A026WMI6   B4JJN3   A0A034W601   B4NPQ3   A0A194Q3W9   A0A0A1XR69   J9KB15   A0A194REM1   A0A1B0ANC8   A0A1A9XH14  

KEGG

101741991    K20840 MFS transporter, PCFT/HCP family, solute carrier family 46, member 3 | (RefSeq) proton-couple

GO

GO:0016021   GO:0055085   GO:0004180   GO:0008237   GO:0008241   GO:0046872   GO:0020037   GO:0000166   GO:0035556   GO:0004383   GO:0031012   GO:0008233   GO:0004298   GO:0005839   GO:0051603   GO:0016740   GO:0003707   GO:0006418   GO:0003824  

PANTHER

PTHR10514  

Length:

513

Number of predicted TMHs:

10

Exp number of AAs in TMHs:

219.64398

Exp number, first 60 AAs:

6.26539

Total prob of N-in:

0.57258

inside

1  -  148

TMhelix

149  -  171

outside

172  -  180

TMhelix

181  -  203

inside

204  -  214

TMhelix

215  -  237

outside

238  -  241

TMhelix

242  -  264

inside

265  -  308

TMhelix

309  -  331

outside

332  -  345

TMhelix

346  -  368

inside

369  -  376

TMhelix

377  -  396

outside

397  -  400

TMhelix

401  -  423

inside

424  -  435

TMhelix

436  -  458

outside

459  -  467

TMhelix

468  -  490

inside

491  -  513

 

 

Pi

201.955199

Theta

178.385681

Tajima's D

0.733647

CLR

0.056781

CSRT

0.583620818959052

Interpretation

Uncertain