Gene

KWMTBOMO11467  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001921

Annotation

actin_[Spodoptera_frugiperda]

Location

Bomo_Chr19(-):6380757-6382166      View in EpiBrowser

Full name

Actin-related protein 3      

Alternative Name

Actin-2
Actin-like protein 3
Actin-like protein 66B

Location in the cell

Cytoplasmic   Reliability : 2.692

CDS

ATGGGAGACCATTTACCAGCTTGTGTTATCGATGTCGGCACCGGGTATACTAAACTGGGTTTTGCCGGTAACAAGGAACCACAGTTTATTATTCCATCAACCATAGCGATAAAAGAAACTGCAAAAGTTGGCGATCAGAGTACTCGGAGGATGACTAAGGCTGTCGAAGATTTGGATTTTTTCATCGGTGATGAAGCTTTTGAAGCCACAGGATACTCTGTAAAGTATCCTGTGCGCCACGGTATCGTAGAAGACTGGGATTTAATGGAAAGGTACATCGAACAGTGCGTGTTTAAGTATCTCCGTGCGGAACCCGAAGATCATCATTTCTTAATGACCGAGCCTCCGCTCAACACTCCAGAAAACAGAGAATATTTAGCCGAAATCATGTTTGAGTCATTTAATGTGCCAGGCCTTTACATTGCTGTACAAGCCGTTCTTGCTTTGGCTGCGTCATGGAAGTCACGTACGTCTGCTGAACGCACCTTCACTGGCATCGTAGTAGACAGCGGAGATGGCGTTACTCACATTGTTCCAGTTGCAGAAGGATATGTTATTGGATCATGTATAAAACACATCCCTATTGCTGGTAGAAACATTACTTCATTTATTCAATCATTACTCCGTGAAAGAGAGGTTGGAATCCCTCCTGAGCAAAGTTTGGAAACTGCCAAAGCTATTAAAGAAAAATACAGTTATATCTGTCCTGACATTGCTAAAGAATTTGCAAAATACGATAGCGATCCTGGTAAATGGATGAAAAAGTACACAGGGATCAATGCTATCACTAAAAACCCATTTACAGTCGATGTTGGCTACGAGCGATTCTTAGGACCTGAGATTTTCTTCCATCCTGAATTTTCAAATGCTGATTTCACTGTACCTTTGAATGAGATGGTTGATGAAGTGATTCAGTCATGCCCCATTGATGTTAGACGAGGATTGTATGGAAACATTGTGTTGTCTGGTGGCTCGACTATGTTCCGTGACTTTGGCAGAAGGTTACAACGTGATATCAAGAGGGCTGTTGATGCAAGATTGAAGCTTTCGACTATGTTATCTGAAGGTCGGATTACCCCTAAACCGATTGATGTACAAGTTGTGTCTCATAACATGCAGAGATATGCTGTGTGGTTCGGAGGCAGTATGCTTGCATCAACACCAGAGTTCTACCAAGTCTGCCATACTAAACAGGCATACATGGAGTATGGTCCTAGTATTTGCAGACACAACCCTGTTTTTGGTACCATGACATAA

Protein

MGDHLPACVIDVGTGYTKLGFAGNKEPQFIIPSTIAIKETAKVGDQSTRRMTKAVEDLDFFIGDEAFEATGYSVKYPVRHGIVEDWDLMERYIEQCVFKYLRAEPEDHHFLMTEPPLNTPENREYLAEIMFESFNVPGLYIAVQAVLALAASWKSRTSAERTFTGIVVDSGDGVTHIVPVAEGYVIGSCIKHIPIAGRNITSFIQSLLREREVGIPPEQSLETAKAIKEKYSYICPDIAKEFAKYDSDPGKWMKKYTGINAITKNPFTVDVGYERFLGPEIFFHPEFSNADFTVPLNEMVDEVIQSCPIDVRRGLYGNIVLSGGSTMFRDFGRRLQRDIKRAVDARLKLSTMLSEGRITPKPIDVQVVSHNMQRYAVWFGGSMLASTPEFYQVCHTKQAYMEYGPSICRHNPVFGTMT

Description

Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). Seems to contact the pointed end of the daughter actin filament (By similarity). Required during embryogenesis for the developmental migration of tail hemocytes anteriorly, along the ventral midline (PubMed:25739458).

Subunit

Component of the Arp2/3 complex.

Similarity

Belongs to the actin family.
Belongs to the actin family. ARP3 subfamily.

Keywords

Actin-binding   ATP-binding   Complete proteome   Cytoplasm   Cytoskeleton   Nucleotide-binding   Reference proteome  

Feature

chain  Actin-related protein 3

Uniprot

H9IXD8   A0A1E1WVA4   A0A0K2CU30   A0A2A4JLE2   A0A0L7KYF0   A0A212EPX7   + More
S4P2D1   A0A194R1J7   A0A194QK00   E3UKI1   Q16MG7   A0A084W2J8   A0A2M3Z8H3   A0A2M4AGI8   A0A2M4BPC3   A0A0L0BV06   A0A1I8PEP1   A0A182LSY2   A0A182PHC4   A0A182YFL6   A0A182V2Z0   A0A182KAF0   B0XB57   A0A182TKS1   A0A182XJ82   A0A182LBB6   Q7PQ13   A0A182RTN0   A0A182HP82   A0A182GQ79   B3M425   W5JTX3   B0X7Y3   T1PAG4   A0A1Q3FAW6   A0A1B0FNA8   A0A1A9YN62   A0A1A9UJA0   A0A1B0AY33   A0A1A9Z2U4   A0A2J7QDC1   A0A1L8EHR7   W8BNI8   A0A1W4VN34   A0A0K8VQF1   B4PCS6   B3NF57   A0A2P8YZG5   A0A0A1X712   I3TBA2   J3JUD8   A0A0J9RSJ9   B4HIZ2   P32392   B4LGZ8   U5EWP9   U4TRH7   V5G413   A0A3B0JYN1   Q29FE3   B4H1G3   E0W211   A0A1Y1KH31   A0A0M4EHX9   B4KWX4   A0A2S2QJR2   A0A067RN38   A0A1A9WSA2   A0A0C4URN5   J9JNQ4   D6WGX8   B4IWR1   A0A1L8E4X2   A0A224XQY8   A0A0V0G5J8   A0A069DU45   A0A0T6BHB1   A0A023FAQ6   B4MXD7   A0A0P4VMK2   R4G5K1   A0A126CQV4   A0A0A9XJ84   A0A336LSC7   A0A1B6ERX1   A0A1B6J725   A0A1D2N0K3   A0A182T9I9   E9FW97   A0A1B6CP75   A0A0P5CCT3   A0A226EWS2   A0A1J1IPX9   R4WPN6   A0A1B6MT27   A0A087TB57   A0A0K8TLS0   A0A293MSR7   A0A0K8R4G6   A0A3B0KTF8  

Pubmed

19121390    26263512    26227816    22118469    23622113    26354079    + More
17510324    24438588    26108605    25244985    20966253    12364791    14747013    17210077    26483478    17994087    20920257    23761445    25315136    24495485    17550304    29403074    25830018    22516182    23537049    22936249    8274139    10731132    12537572    12537569    25739458    15632085    20566863    28004739    24845553    25692689    18362917    19820115    26334808    25474469    27129103    25401762    26823975    27289101    21292972    23691247    26369729   

EMBL

BABH01018005    GDQN01000099    JAT90955.1    KT218672    ODYU01012730    ALA09392.1    + More
SOQ59181.1    NWSH01001178    PCG72232.1    JTDY01004333    KOB68283.1    AGBW02013366    OWR43517.1    GAIX01012080    JAA80480.1    KQ461073    KPJ09726.1    KQ458575    KPJ05704.1    HM449855    ADO32990.1    CH477862    EAT35521.1    ATLV01019621    KE525275    KFB44442.1    GGFM01004050    MBW24801.1    GGFK01006427    MBW39748.1    GGFJ01005754    MBW54895.1    JRES01001294    KNC23875.1    AXCM01006295    DS232614    EDS44110.1    AAAB01008900    EAA09440.2    APCN01002923    JXUM01080018    JXUM01080019    KQ563159    KXJ74378.1    CH902618    EDV40387.1    ADMH02000391    ETN66738.1    DS232468    EDS42202.1    KA645766    AFP60395.1    GFDL01010334    JAV24711.1    CCAG010000676    JXJN01005529    NEVH01015825    PNF26581.1    GFDG01000666    JAV18133.1    GAMC01015273    GAMC01015271    JAB91284.1    GDHF01011236    JAI41078.1    CM000159    EDW93830.1    CH954178    EDV50399.1    PYGN01000270    PSN49643.1    GBXI01007762    JAD06530.1    JQ686945    AFK49794.1    APGK01044967    BT126851    KB741028    AEE61813.1    ENN74843.1    CM002912    KMY98279.1    CH480815    EDW40646.1    X71789    AE014296    AY051859    CH940647    EDW69488.1    GANO01001315    JAB58556.1    KB631073    KB631074    ERL84069.1    ERL84078.1    GALX01003691    JAB64775.1    OUUW01000012    SPP87187.1    CH379067    EAL31312.1    CH479202    EDW30140.1    DS235873    EEB19605.1    GEZM01085910    JAV59898.1    CP012525    ALC43376.1    CH933809    EDW18595.1    GGMS01008796    MBY77999.1    KK852411    KDR24473.1    KJ534552    AIY54293.1    ABLF02031954    KQ971321    EFA00142.1    CH916366    EDV96287.1    GFDF01000307    JAV13777.1    GFTR01006037    JAW10389.1    GECL01002785    JAP03339.1    GBGD01001603    JAC87286.1    LJIG01000220    KRT86720.1    GBBI01000588    JAC18124.1    CH963876    EDW76706.1    GDKW01000816    JAI55779.1    GAHY01000475    JAA77035.1    KC702777    AHG54249.1    GBHO01022817    GBRD01015949    GDHC01020466    JAG20787.1    JAG49877.1    JAP98162.1    UFQT01000150    SSX20916.1    GECZ01031697    GECZ01029286    JAS38072.1    JAS40483.1    GECU01030479    GECU01012734    GECU01002663    JAS77227.1    JAS94972.1    JAT05044.1    LJIJ01000319    ODM98827.1    GL732525    EFX88686.1    GEDC01022173    JAS15125.1    GDIP01172195    LRGB01000024    JAJ51207.1    KZS21570.1    LNIX01000001    OXA61514.1    CVRI01000057    CRL02216.1    AK417626    BAN20841.1    GEBQ01000880    JAT39097.1    KK114397    KFM62346.1    GDAI01002723    JAI14880.1    GFWV01019156    MAA43884.1    GADI01007756    JAA66052.1    SPP87188.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000007151    UP000053240    UP000053268    + More
UP000008820    UP000030765    UP000037069    UP000095300    UP000075883    UP000075885    UP000076408    UP000075903    UP000075881    UP000002320    UP000075902    UP000076407    UP000075882    UP000007062    UP000075900    UP000075840    UP000069940    UP000249989    UP000007801    UP000000673    UP000095301    UP000092444    UP000092443    UP000078200    UP000092460    UP000092445    UP000235965    UP000192221    UP000002282    UP000008711    UP000245037    UP000019118    UP000001292    UP000000803    UP000008792    UP000030742    UP000268350    UP000001819    UP000008744    UP000009046    UP000092553    UP000009192    UP000027135    UP000091820    UP000007819    UP000007266    UP000001070    UP000007798    UP000094527    UP000075901    UP000000305    UP000076858    UP000198287    UP000183832    UP000054359   

PRIDE

H9IXD8    P32392    B4LGZ8   

Pfam

PF00022   Actin        + More
PF01529   DHHC

Interpro

IPR020902   Actin/actin-like_CS        + More
IPR004000   Actin       
IPR015623   Arp3       
IPR001594   Palmitoyltrfase_DHHC       

ProteinModelPortal

H9IXD8   A0A1E1WVA4   A0A0K2CU30   A0A2A4JLE2   A0A0L7KYF0   A0A212EPX7   + More
S4P2D1   A0A194R1J7   A0A194QK00   E3UKI1   Q16MG7   A0A084W2J8   A0A2M3Z8H3   A0A2M4AGI8   A0A2M4BPC3   A0A0L0BV06   A0A1I8PEP1   A0A182LSY2   A0A182PHC4   A0A182YFL6   A0A182V2Z0   A0A182KAF0   B0XB57   A0A182TKS1   A0A182XJ82   A0A182LBB6   Q7PQ13   A0A182RTN0   A0A182HP82   A0A182GQ79   B3M425   W5JTX3   B0X7Y3   T1PAG4   A0A1Q3FAW6   A0A1B0FNA8   A0A1A9YN62   A0A1A9UJA0   A0A1B0AY33   A0A1A9Z2U4   A0A2J7QDC1   A0A1L8EHR7   W8BNI8   A0A1W4VN34   A0A0K8VQF1   B4PCS6   B3NF57   A0A2P8YZG5   A0A0A1X712   I3TBA2   J3JUD8   A0A0J9RSJ9   B4HIZ2   P32392   B4LGZ8   U5EWP9   U4TRH7   V5G413   A0A3B0JYN1   Q29FE3   B4H1G3   E0W211   A0A1Y1KH31   A0A0M4EHX9   B4KWX4   A0A2S2QJR2   A0A067RN38   A0A1A9WSA2   A0A0C4URN5   J9JNQ4   D6WGX8   B4IWR1   A0A1L8E4X2   A0A224XQY8   A0A0V0G5J8   A0A069DU45   A0A0T6BHB1   A0A023FAQ6   B4MXD7   A0A0P4VMK2   R4G5K1   A0A126CQV4   A0A0A9XJ84   A0A336LSC7   A0A1B6ERX1   A0A1B6J725   A0A1D2N0K3   A0A182T9I9   E9FW97   A0A1B6CP75   A0A0P5CCT3   A0A226EWS2   A0A1J1IPX9   R4WPN6   A0A1B6MT27   A0A087TB57   A0A0K8TLS0   A0A293MSR7   A0A0K8R4G6   A0A3B0KTF8  

PDB

6DEC     E-value=0,     Score=1827

KEGG

101744535    K18584 actin-related protein 3 | (RefSeq) actin-related protein 3

GO

GO:0005885   GO:0034314   GO:0005524   GO:0030479   GO:0072553   GO:0030037   GO:0022416   GO:0045887   GO:0007413   GO:0097320   GO:0006886   GO:0010592   GO:0030027   GO:0030589   GO:0007520   GO:0000902   GO:0051491   GO:0016021   GO:0030036   GO:0005737   GO:0003779   GO:0005200   GO:0007010   GO:0005884  

PANTHER

PTHR11937:SF170   PTHR11937   PTHR11937:SF175  

Subcellular location

  

Length:

418

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.674479999999999

Exp number, first 60 AAs:

0.00331

Total prob of N-in:

0.01409

outside

1  -  418

 

 

Pi

153.933328

Theta

44.625725

Tajima's D

-2.19964

CLR

16.487918

CSRT

0.00579971001449927

Interpretation

Uncertain