Gene

KWMTBOMO11453  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001926

Annotation

farnesyl_diphosphate_synthase_[Bombyx_mori]

Location

Bomo_Chr19(-):6068724-6079243      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.578 Mitochondrial   Reliability : 2.057

CDS

ATGTTCTCGACAAAGAAAAGCTTAGAAAAGTTTATGCAGGCGTACAAAAATGAAGTACGCCGGCACATCAGCAAGACAACTAGCGTCACCAATTCTGATGCCATGGCCCCGAGGCTGGACCAGTCGGCGAGCAAGTCACCACAGGCTGAGGAAACCGGACCGAAGAGACTGCTGAAGCTGCAAAAATATCACAGATTCCTGTCGACCCTGACTCCTCAGGAAATGCCGATGGCTACCCGAGGACTGGCCGTTTCCAAGGACCAGTCCCGGGAGTTCATGGCTGTCTTTCCGGACATCGTCAGGGATCTCACTGAGACTGGCAAGCACATTGATGTTCCGGAAGCCAGCAAATGGTTGGCTAAGCTGTTGCAATATAATGTACCAAACGGTAAGAAGAATAGGGGACTGGCCACGATCCTAGCTTACAAAATGCTTGAGAAGAAAGAAAATTTAACGCCAGAGAACATTCTGCTTGCAAACGTTATGGGATGGTGCGTCGAAATGTTCCACACCCACCAACTTCTACTCAACGACATCATGGAAGGTACCACGATGCGTCGCGGCGTTCCGTGCTGGCACCGACGGCCCGACGTCGGTCTAAACGGCATCAACGACGCTGCCCTGATCCAATCCGCAATGTATACCAGTCTGAAACGGCACTTCAACTCCAAGCCATATTACAATTACGTACTTGAAACCTTCAATGAGATGCTGATGAAATGTTCAATGGGTCACTACGTTCAAAAATTAATGCTGAAAACCGATAAGCCAGACTTATCTCTGTTCACAATGGAGAAATACGAAGCGATCACTAAATACAAGACTTCTTATTACACATTCCAAATGCCCGTCTCGTTGGCATTGCTAATGACCGGCGTCGACGATCCAGAGACCCACAGACAAGCTAAAACTATTCTGCTGAAGATGGGAGAGTTCTTCCAAATTCAAGATGATTTTCTGGACTGCTTCGGGGACCCCACGGTGACTGAAAAGTACGGTACCGACATTCAAGATGGAAAATGCACTTGGCTGGCAGTCGTTGCACTGCAGAGGGCAACTCCTGCCCAAAAACAAATCATGGAAGACAATTACGGAGTCAATAAACCTGAAGCTATCGCCAGGATTAAAGATCTCTATGAAGAACTTCAGCTACCCCATACGTACTCGGTCTTCGAAGAAACTACCTACGATCTCCTTAGAACGCAGATCCAACAAGTCACAAGGGGACTACCTCACGAATTGTTCTTCAAAATCTTAGACAACATCTTCAGGCGAAGCGTATTATTGTATGTTTTGGCACCGGCGCTAGATTTGATGAAAGCGCAAGAAAAAAAATTGTAA

Protein

MFSTKKSLEKFMQAYKNEVRRHISKTTSVTNSDAMAPRLDQSASKSPQAEETGPKRLLKLQKYHRFLSTLTPQEMPMATRGLAVSKDQSREFMAVFPDIVRDLTETGKHIDVPEASKWLAKLLQYNVPNGKKNRGLATILAYKMLEKKENLTPENILLANVMGWCVEMFHTHQLLLNDIMEGTTMRRGVPCWHRRPDVGLNGINDAALIQSAMYTSLKRHFNSKPYYNYVLETFNEMLMKCSMGHYVQKLMLKTDKPDLSLFTMEKYEAITKYKTSYYTFQMPVSLALLMTGVDDPETHRQAKTILLKMGEFFQIQDDFLDCFGDPTVTEKYGTDIQDGKCTWLAVVALQRATPAQKQIMEDNYGVNKPEAIARIKDLYEELQLPHTYSVFEETTYDLLRTQIQQVTRGLPHELFFKILDNIFRRSVLLYVLAPALDLMKAQEKKL

Similarity

Belongs to the FPP/GGPP synthase family.

Uniprot

H9IXE3   A5A7A4   Q95P28   O76820   Q1XAA9   A0A0R5Q896   + More
S4PI76   A0A194QJJ2   A0A2A4JG86   A0A2H1WV31   A0A1W5ZM48   A0A212EVH6   Q1XAB0   Q1X8X8   A0A0N1IG58   A0A0L7L5Y7   A0A2P8ZM10   A0A140AZ54   A0A2J7PU44   A0A140AZ53   I1VJ84   M1JS91   A0A0N9EI79   A0A067RTI2   Q56CY7   Q56CY8   A0A2M4BNI6   A0A2M4CPQ8   A0A1Q3FYU3   A0A2M4CPT7   A0A2M4A321   A0A2M3Z093   U5ETY6   A0A0H4IUW5   A0A140AZ52   A0A2S2QJR0   K7IWR9   A0A232EKP8   J9JIS7   Q1X877   A0A182IT14   A0A182V441   A0A2H8TTC7   A0A182FGW5   Q7QIW5   A0A182I2G9   A0A182KQC2   Q17F78   A9Z1D3   Q1X876   A0A023ES27   A0A182RF58   A0A0T6B7F0   Q1X875   A0A182YEJ2   A0A182JX98   B1PI49   G0YZR3   V5I8U9   C7EY44   A0A182QJE2   B0VZA8   Q1X878   W5J8W7   A0A182NK80   A0A1W7R8C9   J9QQQ8   C7EY43   A0A0U2D675   Q1X879   A0A182WLG4   A0A182H5G9   A0A182WWX1   A0A1L1VVV1   A0A182P468   A0A075D844   Q7KAK2   A0A1B6E8U3   B4MFG4   B4P7G6   Q7KN61   B4HNF1   B4J8V8   A0A1Y1LLN4   A0A1W4UGM3   B3NSI9   A0A0J9RAD0   A0A140AZ57   B3MF90   A0A1B6GXY7   Q28Y31   B4GGH4   A0A1J1I5N8   A0A3B0J0A8   B4KR78   A0A1B6IA47   G0YZR4   A9Z1D4   E0VQL3   Q58GE9  

Pubmed

19121390    17628279    10336620    23622113    26354079    28382786    + More
22118469    26227816    29403074    22516182    23537049    24167290    23440195    24845553    15983375    26899871    20075255    28648823    18466770    12364791    14747013    17210077    20966253    17510324    18545274    24945155    25244985    20510361    20920257    23761445    26483478    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    28004739    22936249    15632085    20566863    16640731   

EMBL

BABH01018026    BABH01018027    AB274995    BAF62113.1    AB072589    BAB69490.1    + More
AJ009962    CAA08918.2    AY954921    AAY33487.1    KF841450    AIT55911.1    GAIX01005505    JAA87055.1    KQ458575    KPJ05697.1    NWSH01001679    PCG70440.1    ODYU01011280    SOQ56918.1    KY421778    ARI71314.1    AGBW02012181    OWR45492.1    AY954920    AAY33486.1    AH014859    AY962308    AAY26575.1    KQ460044    KPJ18341.1    JTDY01002731    KOB70830.1    PYGN01000019    PSN57541.1    KT959239    ALL35402.1    NEVH01021208    PNF19862.1    KT959238    ALL35401.1    APGK01054108    APGK01054109    JQ855705    KB741247    KB632281    AFI45068.1    ENN72022.1    ERL91359.1    KC109782    AGE89831.1    KR140284    ALF44684.1    KK852473    KDR23124.1    AY966009    AAX78435.1    AY966008    AAX78434.1    GGFJ01005474    MBW54615.1    GGFL01003136    MBW67314.1    GFDL01002296    JAV32749.1    GGFL01003135    MBW67313.1    GGFK01001820    MBW35141.1    GGFM01001150    MBW21901.1    GANO01002569    JAB57302.1    KP689343    AKO63325.1    KT959237    ALL35400.1    GGMS01008720    MBY77923.1    AAZX01000604    NNAY01003758    OXU18892.1    ABLF02016577    AY968585    AAY33490.3    GFXV01004643    MBW16448.1    AAAB01008807    EAA04004.4    APCN01000156    CH477273    EAT45207.1    EU334430    ABY19312.1    AY968586    AAY33491.1    GAPW01001563    JAC12035.1    LJIG01009346    KRT83264.1    AY968587    AAY33492.1    EU429296    ACA48701.1    HQ850372    AEK32003.1    GALX01004055    JAB64411.1    GQ324702    ACT79809.3    AXCN02000425    DS231813    EDS25700.1    AY968584    AAY33489.2    ADMH02001942    ETN60396.1    GEHC01000234    JAV47411.1    JX308223    AFR31785.1    GQ324701    ACT79808.1    KM514312    AKM16734.1    AY968583    AAY33488.2    JXUM01026170    KQ560746    KXJ81031.1    KC758147    AHH31548.1    KC840040    AHH34857.1    AJ009963    CAA08919.1    GEDC01002947    JAS34351.1    CH940667    EDW57135.1    CM000158    EDW90001.1    AF132554    AE013599    AY071445    AAD27853.1    AAF58670.1    AAL49067.1    CH480816    EDW47387.1    CH916367    EDW02398.1    GEZM01054111    JAV73841.1    CH954179    EDV56491.1    CM002911    KMY92967.1    KT959242    ALL35405.1    CH902619    EDV35564.1    GECZ01021848    GECZ01002488    JAS47921.1    JAS67281.1    CM000071    EAL26135.1    CH479183    EDW35594.1    CVRI01000042    CRK95499.1    OUUW01000001    SPP73997.1    CH933808    EDW08265.1    GECU01030621    GECU01023892    GECU01018894    GECU01006635    GECU01005965    GECU01004889    JAS77085.1    JAS83814.1    JAS88812.1    JAT01072.1    JAT01742.1    JAT02818.1    HQ850373    AEK32004.1    EU334431    EU447786    EU429295    ABY19313.1    ACA35007.1    ACA48700.1    DS235430    EEB15669.1    AY953507    AAX55631.1   

Proteomes

UP000005204    UP000053268    UP000218220    UP000007151    UP000053240    UP000037510    + More
UP000245037    UP000235965    UP000019118    UP000030742    UP000027135    UP000002358    UP000215335    UP000007819    UP000075880    UP000075903    UP000069272    UP000007062    UP000075840    UP000075882    UP000008820    UP000075900    UP000076408    UP000075881    UP000075886    UP000002320    UP000000673    UP000075884    UP000075920    UP000069940    UP000249989    UP000076407    UP000075885    UP000008792    UP000002282    UP000000803    UP000001292    UP000001070    UP000192221    UP000008711    UP000007801    UP000001819    UP000008744    UP000183832    UP000268350    UP000009192    UP000009046   

PRIDE

H9IXE3    A5A7A4    Q95P28    Q7KAK2    Q7KN61   

Pfam

PF00348   polyprenyl_synt        + More
PF13344   Hydrolase_6
PF00069   Pkinase

Interpro

IPR033749   Polyprenyl_synt_CS        + More
IPR008949   Isoprenoid_synthase_dom_sf       
IPR039702   FPS1       
IPR000092   Polyprenyl_synt       
IPR036412   HAD-like_sf       
IPR023214   HAD_sf       
IPR006357   HAD-SF_hydro_IIA       
IPR017441   Protein_kinase_ATP_BS       
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       
IPR000961   AGC-kinase_C       
IPR000719   Prot_kinase_dom       

SUPFAM

SSF48576   SSF48576        + More
SSF56784   SSF56784       
SSF56112   SSF56112       

Gene 3D

1.10.600.10     3.40.50.1000    

ProteinModelPortal

H9IXE3   A5A7A4   Q95P28   O76820   Q1XAA9   A0A0R5Q896   + More
S4PI76   A0A194QJJ2   A0A2A4JG86   A0A2H1WV31   A0A1W5ZM48   A0A212EVH6   Q1XAB0   Q1X8X8   A0A0N1IG58   A0A0L7L5Y7   A0A2P8ZM10   A0A140AZ54   A0A2J7PU44   A0A140AZ53   I1VJ84   M1JS91   A0A0N9EI79   A0A067RTI2   Q56CY7   Q56CY8   A0A2M4BNI6   A0A2M4CPQ8   A0A1Q3FYU3   A0A2M4CPT7   A0A2M4A321   A0A2M3Z093   U5ETY6   A0A0H4IUW5   A0A140AZ52   A0A2S2QJR0   K7IWR9   A0A232EKP8   J9JIS7   Q1X877   A0A182IT14   A0A182V441   A0A2H8TTC7   A0A182FGW5   Q7QIW5   A0A182I2G9   A0A182KQC2   Q17F78   A9Z1D3   Q1X876   A0A023ES27   A0A182RF58   A0A0T6B7F0   Q1X875   A0A182YEJ2   A0A182JX98   B1PI49   G0YZR3   V5I8U9   C7EY44   A0A182QJE2   B0VZA8   Q1X878   W5J8W7   A0A182NK80   A0A1W7R8C9   J9QQQ8   C7EY43   A0A0U2D675   Q1X879   A0A182WLG4   A0A182H5G9   A0A182WWX1   A0A1L1VVV1   A0A182P468   A0A075D844   Q7KAK2   A0A1B6E8U3   B4MFG4   B4P7G6   Q7KN61   B4HNF1   B4J8V8   A0A1Y1LLN4   A0A1W4UGM3   B3NSI9   A0A0J9RAD0   A0A140AZ57   B3MF90   A0A1B6GXY7   Q28Y31   B4GGH4   A0A1J1I5N8   A0A3B0J0A8   B4KR78   A0A1B6IA47   G0YZR4   A9Z1D4   E0VQL3   Q58GE9  

PDB

6B07     E-value=6.40508e-91,     Score=853

KEGG

692433    K00787 farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] | (RefSeq) Fps, BmFPS; farnesyl pyrophosp

PATHWAY

00900    Terpenoid backbone biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0045337   GO:0004161   GO:0033384   GO:0004337   GO:0005737   GO:0008354   GO:0004674   GO:0005524   GO:0008299   GO:0007264   GO:0008270   GO:0004180   GO:0007016   GO:0016010   GO:0016740   GO:0003707   GO:0006418   GO:0003824  

PANTHER

PTHR11525  

Length:

446

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.08833

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01035

outside

1  -  446

 

 

Pi

187.032772

Theta

167.933361

Tajima's D

0.261466

CLR

1.657097

CSRT

0.443377831108445

Interpretation

Uncertain