Gene

KWMTBOMO11441

Pre Gene Modal

BGIBMGA002632

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr19(+):5820954-5825156      View in EpiBrowser

Full name

Queuine tRNA-ribosyltransferase accessory subunit 2      

Alternative Name

Queuine tRNA-ribosyltransferase domain-containing protein 1

Location in the cell

Mitochondrial   Reliability : 2.129 Nuclear   Reliability : 1.801

CDS

ATGACTCGACTTGAACGGCTACCCCAAGTGGCTAAAGTCATGCAAGAATACAACATTCACATTCTTGGATTGAGTGAGACGAGATGGAACGGTTTTGGAGAAACGCAATGTGATTTTGGATACTCGTTATTGTACAGTGGTAAGGAAGAGGATGCGACCCGAGAGTATGGCGTGGGTTTGCTGCTAAGTCGCAGCGCTAAAAGTAGCTTACTCTCTTGGAAGCCAGTCTCGGAACGAATAATATGCGCCAGATTCTCGACACGAGTACGGAAGGTGACAGTGATACAATGCTACGCTCCCACTAACTCTGCTTCGACCGATGTAAAGTCACAATTCTACGAACAGCTGGGGCATACACTCAAAGGCATCAAGAAACAAGATATCGTGATTCTCATGGGCGACATAAATGCGAAGATGGGAAATGACAATGTAGACCGCGAATATTACATGGGACAATATGGGGCAACCGGAACTATTAACGAAAACGGAGAACTTTTCGGTGATCTATGTTCCACACATGGTCTAGTTATTGGAGGTACCCTATTTAAACATAAGGAATGTCATAAAGTTACTTGGATATCACCGGACGGAAAGACAAAGAACCAAATCGATCACGTAGCTATCAGTAAGACATGGCGCTCTTCTCTTCTTGATGTGCGAAATAAGCGTGGCGCAGACATTGACAGTGATCACCATCTGGTGGTAGCAGAAGTTCGTCTTAAAATAGCAGTTCCCCACAGAAAGCCAGATAAAGCAGCTAGAAAATTTAATATCCAAAAACTGGAAGATAGCAATTGCCGAGAGAAGTTCAGCTTATCTCTCAAAAATAGTTTCGAGCTGCTTAAGGAAATAGAGGATGAGCAGATGGACGAGACGTGGGACCGCATACGTGGTGCTTATAATAAAGCTGCTAAGGAAGTATTGGGGTATACCAATACAAAGCAAGAACCTTGGATGTCAGCAGAGCTTTGGGCAGCCATCGAGAAGAGACAACTTTTGAACACTCAGATTTTAGGCTCCCCTTCAGATGCTTTGTTGCGTCGGGAATACTCATCCATGCGATTAGTAATTAGAAAGCTGGCTAGGAGAGATCAGCGAAATGCAATCGATGAGCTAGCAGACCGAGCAAAATTGGCAGCCAAGAGGCAAGATATGAAAGAGCTTTACGATGTCACCAAGCGGATAATAAACAAAAAACATCATGCACGGAAAAAACCACTGAAAGACTGCTCGGGTCAGCTACTATGTACCACGGAAGAGCAGCTCGTGCGCTGGACGGAACACTTTACTAAGTTGCTGTCCAAATGTCAGTCCCAACCCACAGACGGAATATCAGTACCCGACTTGCCTTTGGATATACCTATTGCACCGCCCACCTTTAATGAAATAGTAAAGGCAATTAAACAGCTGAAACCAGGTAAGGCCCCCGGTATTGACAATATCAATGCCGAAATGCTGAAGGCTGATGCACCGAGATCTGCAAGCTTGCTATATCCGCTCATCGTAAGGATTTGGGAGACTGAGCAAATACCGTCTCAATGGAAGCAGGGACTACTCGTGAAAGTTCCGAAGAAGGGCGATTTGTCTTCTTGTGACAACTGGAGAGGCATTACACTTCTTCCTTGCGCAGCAAAGGTCTTGGCTAGATTACTTCTAAACCGGATGTCCAAAAAGATCACTGGAACTCTTCGGGAGGAGCAAGCAGGTTTCTTACCGGGCCGATCATGCACAGACCATACAAACACTCTTCGCATCCTCATAGAACAAAGTGTCGAATGGCAGACTGAAATGATTCTTACGTTTGTAGACTTTGAGAAAGCGTTTGACACTGTACAGTGGAGCAAAATGTGGACCTGCTTAAAACAAAGAGGTATACCAAATAAAATCATTGGTATAATCCAGGCCTTATACAGAGGATAA

Protein

MTRLERLPQVAKVMQEYNIHILGLSETRWNGFGETQCDFGYSLLYSGKEEDATREYGVGLLLSRSAKSSLLSWKPVSERIICARFSTRVRKVTVIQCYAPTNSASTDVKSQFYEQLGHTLKGIKKQDIVILMGDINAKMGNDNVDREYYMGQYGATGTINENGELFGDLCSTHGLVIGGTLFKHKECHKVTWISPDGKTKNQIDHVAISKTWRSSLLDVRNKRGADIDSDHHLVVAEVRLKIAVPHRKPDKAARKFNIQKLEDSNCREKFSLSLKNSFELLKEIEDEQMDETWDRIRGAYNKAAKEVLGYTNTKQEPWMSAELWAAIEKRQLLNTQILGSPSDALLRREYSSMRLVIRKLARRDQRNAIDELADRAKLAAKRQDMKELYDVTKRIINKKHHARKKPLKDCSGQLLCTTEEQLVRWTEHFTKLLSKCQSQPTDGISVPDLPLDIPIAPPTFNEIVKAIKQLKPGKAPGIDNINAEMLKADAPRSASLLYPLIVRIWETEQIPSQWKQGLLVKVPKKGDLSSCDNWRGITLLPCAAKVLARLLLNRMSKKITGTLREEQAGFLPGRSCTDHTNTLRILIEQSVEWQTEMILTFVDFEKAFDTVQWSKMWTCLKQRGIPNKIIGIIQALYRG

Description

Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

Cofactor

Zn(2+)

Subunit

Heterodimer of a catalytic subunit and an accessory subunit.

Similarity

Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.

Uniprot

D7F173   H9IZE7   A0A146MF87   A0A3S0Z3I7   A0A1B0GLA1   A0A336MSP8   + More
A0A3B1KH88   Q4QQE8   A0A2B4R8E3   A0A2B4RLZ4   C7C207   A0A2T7PJY8   A0A183MMI0   A0A1S3ISC1   W4XQE1   W5JEC3   H3B4N3   A0A182FVE7   A0A183MGB1   A0A183LTH6   A0A0B7BT32   A0A0A9YT65   A0A2G8K194   A0A183M4H1   A0A336M488   A0A3S1AZZ4   A0A2T7PGW1   A0A2G8LPK9   A0A183MP16   A0A2T7NHE8   A0A183N5W2   A0A183KHV6   A0A183MS45   A0A183LFM6   A0A183L9Y2   A0A2S2PT92   A0A183NCM3   A0A2W1BNH4   A0A183MTT9   A0A146KNZ7   A0A2B7ZXS2   A0A023F0H0   A0A023F0F3   D7F174   A0A183MYH2   A0A023EX67   A0A183MSD1   A0A183MMG7   A0A183K1M3   A0A2P8XC08   A0A183ME56   A0A183MVQ1   J9LWM8   A0A016VQL3   A0A0K8SN56   A0A2P8ZLT6   W4YIG0   A0A2P8Z488   A0A060Q6A2   A0A2P8YWA2   J9L6X2   A0A023F0M0   A0A2P8Y2S1   A0A0U4HM41   D7F161   A0A2S2QKG5   A0A183L9X8   A0A183NBK2   X1WTQ9   A0A0V0G8V1   A0A1B0CNV0   A0A023EWL3   A0A2P8ZFZ0   A0A183N4V7   A0A023EZ68   J9LFP1   A0A069DWU6   A0A069DWR4   A0A0J7KMY2   A0A183LK64   A0A0R3Q7D3   A0A2P8Z313   J9KNQ8   A0A2P8ZA67  

Pubmed

20470440    19121390    26823975    25329095    15939396    20920257    + More
23761445    9215903    25401762    29023486    28756777    25474469    24945155    29403074    25730766    25527032    26334808   

EMBL

FJ265558    ADI61826.1    BABH01014180    BABH01014181    BABH01014182    BABH01014183    + More
GDHC01000226    JAQ18403.1    RQTK01002506    RUS68506.1    AJWK01034673    UFQT01001780    SSX31783.1    BN000794    CAJ00236.1    LSMT01001244    PFX12648.1    LSMT01000478    PFX17357.1    FN356221    CAX83710.1    PZQS01000003    PVD33720.1    UZAI01017328    VDP23394.1    AAGJ04045270    ADMH02001629    ETN61698.1    AFYH01088828    UZAI01016872    VDP17428.1    UZAI01002797    VDO74729.1    HACG01049283    CEK96148.1    GBHO01009326    JAG34278.1    MRZV01000990    PIK41764.1    UZAI01005910    VDO92622.1    UFQS01000142    UFQT01000142    SSX00428.1    SSX20808.1    RQTK01002554    RUS68494.1    PZQS01000004    PVD32651.1    MRZV01000018    PIK62110.1    UZAI01017464    VDP25179.1    PZQS01000012    PVD20578.1    UZAI01019871    VDP48262.1    UZAK01036860    VDP56899.1    UZAI01017784    VDP29476.1    UZAI01000669    VDO55444.1    UZAI01000113    VDO48731.1    GGMR01020071    MBY32690.1    UZAI01022444    VDP57962.1    KZ150025    PZC74827.1    UZAI01017973    VDP31675.1    GDHC01021627    JAP97001.1    PDHN01000949    PGH37547.1    GBBI01004263    JAC14449.1    GBBI01004261    JAC14451.1    FJ265559    ADI61827.1    UZAI01018571    VDP38269.1    GAPW01000107    JAC13491.1    UZAI01017810    VDP29861.1    UZAI01017324    VDP23363.1    UZAK01032956    VDP33068.1    PYGN01003402    PSN29545.1    UZAI01016773    VDP15570.1    UZAI01018190    VDP34363.1    ABLF02042851    JARK01001341    EYC29874.1    GBRD01011073    JAG54751.1    PYGN01000020    PSN57453.1    AAGJ04063063    AAGJ04063064    AAGJ04063065    PYGN01000203    PSN51319.1    HE799691    CCH14900.1    PYGN01000324    PSN48495.1    ABLF02018097    ABLF02043469    ABLF02056908    GBBI01004198    JAC14514.1    PYGN01001004    PSN38555.1    KU311054    ALX81665.1    FJ265546    ADI61814.1    GGMS01009011    MBY78214.1    UZAI01000112    VDO48722.1    UZAI01021623    VDP55993.1    ABLF02035454    ABLF02035459    ABLF02035461    ABLF02042121    GECL01001585    JAP04539.1    AJWK01020943    GAPW01000120    JAC13478.1    PYGN01000070    PSN55417.1    UZAI01019647    VDP46800.1    GBBI01004199    JAC14513.1    ABLF02066124    GBGD01000583    JAC88306.1    GBGD01000559    JAC88330.1    LBMM01005351    KMQ91586.1    UZAI01001301    VDO60450.1    UZAG01001147    VDO10529.1    PYGN01000219    PSN50892.1    ABLF02039015    PYGN01000129    PSN53384.1   

Proteomes

UP000005204    UP000271974    UP000092461    UP000018467    UP000225706    UP000245119    + More
UP000050790    UP000277204    UP000085678    UP000007110    UP000000673    UP000008672    UP000069272    UP000230750    UP000050789    UP000245037    UP000007819    UP000024635    UP000036403    UP000050602   

PRIDE

D7F173    H9IZE7    D7F174    D7F161   

Pfam

PF00078   RVT_1        + More
PF01702   TGT
PF03372   Exo_endo_phos
PF14529   Exo_endo_phos_2
PF00069   Pkinase

Interpro

IPR000477   RT_dom        + More
IPR036691   Endo/exonu/phosph_ase_sf       
IPR027124   Swc5/CFDP2       
IPR036511   TGT-like_sf       
IPR028592   QTRTD1       
IPR002616   tRNA_ribo_trans-like       
IPR005135   Endo/exonuclease/phosphatase       
IPR000719   Prot_kinase_dom       
IPR017441   Protein_kinase_ATP_BS       
IPR011009   Kinase-like_dom_sf       
IPR000637   HMGI/Y_DNA-bd_CS       

SUPFAM

SSF56219   SSF56219        + More
SSF51713   SSF51713       
SSF56112   SSF56112       

Gene 3D

3.60.10.10     3.20.20.105    

ProteinModelPortal

D7F173   H9IZE7   A0A146MF87   A0A3S0Z3I7   A0A1B0GLA1   A0A336MSP8   + More
A0A3B1KH88   Q4QQE8   A0A2B4R8E3   A0A2B4RLZ4   C7C207   A0A2T7PJY8   A0A183MMI0   A0A1S3ISC1   W4XQE1   W5JEC3   H3B4N3   A0A182FVE7   A0A183MGB1   A0A183LTH6   A0A0B7BT32   A0A0A9YT65   A0A2G8K194   A0A183M4H1   A0A336M488   A0A3S1AZZ4   A0A2T7PGW1   A0A2G8LPK9   A0A183MP16   A0A2T7NHE8   A0A183N5W2   A0A183KHV6   A0A183MS45   A0A183LFM6   A0A183L9Y2   A0A2S2PT92   A0A183NCM3   A0A2W1BNH4   A0A183MTT9   A0A146KNZ7   A0A2B7ZXS2   A0A023F0H0   A0A023F0F3   D7F174   A0A183MYH2   A0A023EX67   A0A183MSD1   A0A183MMG7   A0A183K1M3   A0A2P8XC08   A0A183ME56   A0A183MVQ1   J9LWM8   A0A016VQL3   A0A0K8SN56   A0A2P8ZLT6   W4YIG0   A0A2P8Z488   A0A060Q6A2   A0A2P8YWA2   J9L6X2   A0A023F0M0   A0A2P8Y2S1   A0A0U4HM41   D7F161   A0A2S2QKG5   A0A183L9X8   A0A183NBK2   X1WTQ9   A0A0V0G8V1   A0A1B0CNV0   A0A023EWL3   A0A2P8ZFZ0   A0A183N4V7   A0A023EZ68   J9LFP1   A0A069DWU6   A0A069DWR4   A0A0J7KMY2   A0A183LK64   A0A0R3Q7D3   A0A2P8Z313   J9KNQ8   A0A2P8ZA67  

KEGG

NA   

GO

GO:0004519   GO:0003964   GO:0008479   GO:0101030   GO:0005737   GO:0046872   GO:0004672   GO:0005524   GO:0016021   GO:0006355  

PANTHER

PTHR23227  

Subcellular location

Cytoplasm  

Length:

639

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04701

Exp number, first 60 AAs:

0.00013

Total prob of N-in:

0.00042

outside

1  -  639

 

 

Pi

299.274962

Theta

169.2112

Tajima's D

2.53249

CLR

0.883176

CSRT

0.950052497375131

Interpretation

Uncertain