Gene

KWMTBOMO11440

Annotation

endonuclease-reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr19(-):5810849-5813373      View in EpiBrowser

Full name

Guanylate cyclase      

Location in the cell

Nuclear   Reliability : 2.773

CDS

ATGGCTACATCAGATCATAAGTTTGAATTAATGATGAAAGATCTTAAAAGAAAACGCGCATCTATTAAATGTCGTTTGACTAACTTTGGAAAATATGTGAATTCATTCGAAGGTGTAGAATTAACTGTTCATCAACGTACCGAGCTAAAACTGCGGATGGCAGGATCGCAAAGTTTAATGAATGATTTTAACCTCGTTCAGACACAAATAGAAGACATTAGTGTAGAAATCGACATAGAAAAACAGTTAGAATCGCGTGAAGATTTCGAGCAAAAATATTATAATATTCTTGCCCTTGCTGAATGTCTGACCACCGCTGATGAAAAGTCAAAAGACGAAGAAAAAGTACCGAAACAATGGTGTGCATCAGACATAATTTTACTCTTCAAGAAAGGATGTCCCTTAGATATAGGAAATTATAGACCCATAAGCCTGCTGGCGAGCATATATAAACTATTTTCATCCATAATTTTAAAGAGAATATCCGACGACATCGACAAGCTGCAACCAAAGGAGCAGGCGGGATTCAGATCAGGCTTTAGCACAATGGACCACATACAAACACTAGAGCAGGTCATAGAAAAATACAGAGAATATAAAAGACCTCTGTATGTGGCCTTCATTGACTACAGTAAAGCTTTCGACAGCATCAGTCACTGTTCAATCTGGAACGCATTACAACAATCAAATGTTAACTATAAATACATCAATATCTTGAAATATATCTACACAAAAAGTACGAGCAGAGTTAAATTAGAAACTAGAGGAGACGAGATAAAAATAGAACGAGGAGTCAGACAGGGAGATCCTCTTTCCCCGAAGCTGTTCATAGCAGTACTTGAAACTATTTTTCAAAAACTAGATTGGAAAAAAAGGGGAGTGTACATAAACGGACACTACCTAAACCATCTGAGGTTCGCTGACGATGTTGTTATAATTGCTGAAACTGCCAAAGACCTAGAGGAAATGATGAGATCACTGGACTGCGAAAGTTCAAAAATCGGCCTAGAAATGAATGTAAGCAAAACTAAGATATTAACCAACAATCACGAACGCCCGATAATGATAAAAGGTAACAATATAGAATACGTCAGCGAATACATCTACTTAGGGAAGCAAATCTCATTCAAAACGACAAGCAACGAAGAAGAAGTAACAAGAAGAATCAACGCAACTTGGAAGAAATTCTGGGCACTAAAAGAAATCCTAAAAGGGAACTACAGCTTGCGTATGAAAAGGGCAACATTTGATACATGCCTGTTACCCTGCTTGTTGTATGGCTGCCAAACGTGGATATTTACAAATAAAATAAAACAAAAAATTAAATGCAGTCAAACAGCCATGGAAAGGAGCATGTTGAAAATTAGAAGAATACATAGAATTAAGAATGAAAGCATTCGTCAAAAAACTAAACTTACCGATGCTCTCAGCCACGCACTCTCACTTAAGTGGAGATGGGCCGGACACATCTCACGATACCCAGACAAAAGATGGACCATTGAAGCCACACGATGGAAAGGACCAATGGGGAAAAGGAATGTTGGTCGACAATTAAGACGATGGGCCGATGACATAACACACGTCGCAGGAAACGACTGGATAAAATCAGGCAAGGACAAGGAGTCATGGAAAAGGATGGAGGAGGCCTTTACCCAGATAGGGGTCCAAATCTCATAA

Protein

MATSDHKFELMMKDLKRKRASIKCRLTNFGKYVNSFEGVELTVHQRTELKLRMAGSQSLMNDFNLVQTQIEDISVEIDIEKQLESREDFEQKYYNILALAECLTTADEKSKDEEKVPKQWCASDIILLFKKGCPLDIGNYRPISLLASIYKLFSSIILKRISDDIDKLQPKEQAGFRSGFSTMDHIQTLEQVIEKYREYKRPLYVAFIDYSKAFDSISHCSIWNALQQSNVNYKYINILKYIYTKSTSRVKLETRGDEIKIERGVRQGDPLSPKLFIAVLETIFQKLDWKKRGVYINGHYLNHLRFADDVVIIAETAKDLEEMMRSLDCESSKIGLEMNVSKTKILTNNHERPIMIKGNNIEYVSEYIYLGKQISFKTTSNEEEVTRRINATWKKFWALKEILKGNYSLRMKRATFDTCLLPCLLYGCQTWIFTNKIKQKIKCSQTAMERSMLKIRRIHRIKNESIRQKTKLTDALSHALSLKWRWAGHISRYPDKRWTIEATRWKGPMGKRNVGRQLRRWADDITHVAGNDWIKSGKDKESWKRMEEAFTQIGVQIS

Catalytic Activity

GTP = 3',5'-cyclic GMP + diphosphate

Uniprot

A0A2W1B5F8   D7F177   D7F178   A0A2H1WF27   A0A2W1BCS2   A0A2W1BDX2   + More
D7F179   A0A2H1VY30   A0A3S2TAR4   A0A023EXV2   D7F176   D7F164   D7F157   A4KWF2   A4KWG0   D7F166   D7F165   A0A2G8JFM9   A0A2W1BZV1   A0A069DZM5   A0A2H1VS24   A0A2G8K4F2   W4YXJ1   A0A2W1BLC9   D7F160   A0A016UMK7   A0A2W1BMB6   A0A016RXU5   D7F158   D7F159   A0A016VV56   A0A016RYK0   A0A016V7H3   A0A016S1D2   A0A3S2KX72   A0A016UTS3   A0A016UWI5   A0A0K0FAW8   A0A016WPY4   A0A016WCB8   A0A016ULU9   A0A0R3Q573   W4YXJ0   A0A1E1X2U1   A0A0N5C0B1   A0A016SGC3   A0A016USZ5   A0A016SX67   A0A016TQ81   A0A016UUF2   A0A016VBB9   A0A016VN75   A0A016TH80   A0A016VGM4   A0A016SSP6   A0A016VRX3   A0A016T7J7   A0A016VW83   A0A016TIA8   A0A016VMK8   A0A016UGM6   A0A016VTY8   A0A016TXK2   A0A016UHW4   A0A016S403   A0A016U784   A0A016TNH6   A0A016TMT8   A0A016TNS4   A0A016TNL1   A0A016WFS9   W6NEE1   A0A016T590   A0A016S5A1   A0A016WVQ3   A0A016UEM0   A0A016T5Z1   A0A016T4C4   A0A016SWH8   A0A016T636   A0A016US53   A0A016WKT9   A0A016URH5   A0A016W1X2   A0A016U6B7   A0A016WVJ5   A0A016TK92   A0A016SY13   A0A016WEQ1   A0A016VLP0   A0A016SCL7   A0A016VGA0   A0A016WYN9   A0A016TQJ1   A0A016VEC1   A0A016WJL5   A0A016VCD9   A0A016SCZ8   A0A016UJS4  

EC Number

4.6.1.2

Pubmed

28756777    20470440    25474469    17360547    29023486    26334808    + More
25730766    28503490   

EMBL

KZ150317    PZC71439.1    FJ265562    ADI61830.1    FJ265563    ADI61831.1    + More
ODYU01008249    SOQ51673.1    KZ150485    PZC70710.1    KZ150108    PZC73382.1    FJ265564    ADI61832.1    ODYU01004982    SOQ45402.1    RSAL01002362    RVE40503.1    GBBI01004876    JAC13836.1    FJ265561    ADI61829.1    FJ265549    ADI61817.1    FJ265542    ADI61810.1    EF113398    EF113401    ABO45231.1    EF113402    ABO45239.1    FJ265551    ADI61819.1    FJ265550    ADI61818.1    MRZV01002136    PIK34564.1    KZ149907    PZC78256.1    GBGD01000380    JAC88509.1    ODYU01004088    SOQ43598.1    MRZV01000899    PIK42833.1    AAGJ04144474    KZ149985    PZC75698.1    FJ265545    ADI61813.1    JARK01001370    EYC16151.1    KZ150072    PZC74016.1    JARK01001677    EYB83168.1    FJ265543    ADI61811.1    FJ265544    ADI61812.1    JARK01001340    EYC31295.1    EYB83167.1    JARK01001351    EYC23395.1    JARK01001655    EYB84321.1    RSAL01002130    RVE40575.1    JARK01001362    EYC18844.1    EYC18843.1    JARK01000173    EYC41342.1    JARK01000388    EYC37469.1    EYC16150.1    UZAG01000503    VDO08661.1    AAGJ04050748    GFAC01005640    JAT93548.1    JARK01001568    EYB89432.1    JARK01001364    EYC18031.1    JARK01001500    JARK01001343    EYB95040.1    EYC28825.1    JARK01001423    EYC04578.1    JARK01001361    EYC19034.1    JARK01001349    EYC24735.1    JARK01001344    EYC28218.1    JARK01001438    EYC02012.1    JARK01001346    EYC26784.1    JARK01001517    EYB93530.1    JARK01001341    EYC29807.1    JARK01001736    JARK01001462    JARK01001379    JARK01001338    EYB80775.1    EYB98943.1    EYC13646.1    EYC33347.1    EYC31302.1    JARK01001434    EYC02684.1    EYC28635.1    JARK01001378    EYC13977.1    EYC30223.1    JARK01001406    EYC07496.1    JARK01001376    EYC14422.1    JARK01001639    EYB85201.1    JARK01001389    EYC11015.1    JARK01001424    EYC04315.1    EYC04314.1    EYC04317.1    EYC04316.1    JARK01000302    EYC38674.1    CAVP010058300    CDL94394.1    JARK01001473    EYB97806.1    JARK01001630    EYB85641.1    JARK01000077    EYC43894.1    JARK01001380    EYC13322.1    JARK01001470    JARK01000204    EYB98082.1    EYC40602.1    JARK01001475    EYB97550.1    JARK01001502    EYB94855.1    EYB98081.1    EYC40601.1    JARK01001365    EYC18010.1    JARK01000248    EYC39628.1    EYC18009.1    EYC33297.1    EYC10874.1    JARK01000083    EYC43695.1    JARK01001432    EYC03125.1    JARK01001497    EYB95322.1    JARK01000347    EYC38051.1    EYC28216.1    JARK01001628    JARK01001583    JARK01001528    JARK01001506    JARK01001467    JARK01001463    JARK01001457    JARK01001420    JARK01001403    JARK01001371    JARK01001369    JARK01001360    JARK01001353    JARK01000603    JARK01000080    EYB85741.1    EYB88438.1    EYB92544.1    EYB94540.1    EYB98080.1    EYB98468.1    EYB98899.1    EYB99568.1    EYC03088.1    EYC05014.1    EYC08153.1    EYC15852.1    EYC16408.1    EYC19456.1    EYC22445.1    EYC24734.1    EYC24778.1    EYC24866.1    EYC33488.1    EYC35672.1    EYC43798.1    EYC26445.1    JARK01000063    EYC44387.1    JARK01001421    EYC04912.1    JARK01001348    EYC25048.1    JARK01000256    EYC39462.1    EYC25050.1    JARK01001581    EYB88505.1    JARK01001372    EYC15614.1   

Proteomes

UP000283053    UP000230750    UP000007110    UP000024635    UP000035680    UP000050602    + More
UP000046392    UP000025227   

PRIDE

D7F177    D7F178    D7F179    D7F176    D7F164    D7F157    + More
D7F166    D7F165    D7F160    D7F158    D7F159   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF01826   TIL
PF01094   ANF_receptor
PF07714   Pkinase_Tyr
PF00211   Guanylate_cyc

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR036084   Ser_inhib-like_sf       
IPR002919   TIL_dom       
IPR001828   ANF_lig-bd_rcpt       
IPR001245   Ser-Thr/Tyr_kinase_cat_dom       
IPR011009   Kinase-like_dom_sf       
IPR001170   ANPR/GUC       
IPR001054   A/G_cyclase       
IPR028082   Peripla_BP_I       
IPR000719   Prot_kinase_dom       
IPR029787   Nucleotide_cyclase       
IPR029052   Metallo-depent_PP-like       

SUPFAM

SSF56219   SSF56219        + More
SSF57567   SSF57567       
SSF53822   SSF53822       
SSF55073   SSF55073       
SSF56112   SSF56112       

Gene 3D

3.60.10.10     3.30.70.1230     3.60.21.10    

ProteinModelPortal

A0A2W1B5F8   D7F177   D7F178   A0A2H1WF27   A0A2W1BCS2   A0A2W1BDX2   + More
D7F179   A0A2H1VY30   A0A3S2TAR4   A0A023EXV2   D7F176   D7F164   D7F157   A4KWF2   A4KWG0   D7F166   D7F165   A0A2G8JFM9   A0A2W1BZV1   A0A069DZM5   A0A2H1VS24   A0A2G8K4F2   W4YXJ1   A0A2W1BLC9   D7F160   A0A016UMK7   A0A2W1BMB6   A0A016RXU5   D7F158   D7F159   A0A016VV56   A0A016RYK0   A0A016V7H3   A0A016S1D2   A0A3S2KX72   A0A016UTS3   A0A016UWI5   A0A0K0FAW8   A0A016WPY4   A0A016WCB8   A0A016ULU9   A0A0R3Q573   W4YXJ0   A0A1E1X2U1   A0A0N5C0B1   A0A016SGC3   A0A016USZ5   A0A016SX67   A0A016TQ81   A0A016UUF2   A0A016VBB9   A0A016VN75   A0A016TH80   A0A016VGM4   A0A016SSP6   A0A016VRX3   A0A016T7J7   A0A016VW83   A0A016TIA8   A0A016VMK8   A0A016UGM6   A0A016VTY8   A0A016TXK2   A0A016UHW4   A0A016S403   A0A016U784   A0A016TNH6   A0A016TMT8   A0A016TNS4   A0A016TNL1   A0A016WFS9   W6NEE1   A0A016T590   A0A016S5A1   A0A016WVQ3   A0A016UEM0   A0A016T5Z1   A0A016T4C4   A0A016SWH8   A0A016T636   A0A016US53   A0A016WKT9   A0A016URH5   A0A016W1X2   A0A016U6B7   A0A016WVJ5   A0A016TK92   A0A016SY13   A0A016WEQ1   A0A016VLP0   A0A016SCL7   A0A016VGA0   A0A016WYN9   A0A016TQJ1   A0A016VEC1   A0A016WJL5   A0A016VCD9   A0A016SCZ8   A0A016UJS4  

PDB

6AR3     E-value=0.00285995,     Score=98

KEGG

101744367    no KO assigned | (RefSeq) uncharacterized LOC101744367

GO

GO:0004519   GO:0003964   GO:0005524   GO:0004672   GO:0004383   GO:0016021   GO:0035556  

Length:

558

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.53579

Exp number, first 60 AAs:

0.0079

Total prob of N-in:

0.00183

outside

1  -  558

 

 

Pi

218.328364

Theta

197.060936

Tajima's D

2.775008

CLR

136.050559

CSRT

0.966501674916254

Interpretation

Uncertain