Gene

KWMTBOMO11412  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001876

Annotation

PREDICTED:_alpha-amylase_2-like_[Bombyx_mori]

Location

Bomo_Chr19(+):4992565-5003508      View in EpiBrowser

Full name

Alpha-amylase       + More
Alpha-amylase 4N      
Alpha-amylase 2      
Alpha-amylase 1      

Location in the cell

Extracellular   Reliability : 2.595

CDS

ATGGTGAAGCATATACTCTTGTCATGGTTATTGACTTTGGCAACAAGTGTGGTTGCGTACAAAAACCCGCACTATGTGACCGGTCGTTCTGTCAACGTGCATCTTTTCGAATGGAAATGGAACGACATTGCTGACGAGTGTGAGCGATTCTTGGGACCTAGAGGCTTTGGAGGAATACAGATATCGCCCCCCAACGAGAATGTTGTGCTATGGACATACAACAGACCCTGGTGGGAGAGATACCAGCCGATTTCATATGAGCTAGTAACTCGCTCAGGAAATGAAAGGCAATTCGCTGATATGGTGAGGAGATGCAATGCTGCTGGAGTTAGGATTTACGTGGACGCCGTCATTAATCATATGACTGGCGAACCTCCAGAGAATATCGGGACTGCGGGTAACACTGCTGTTTACCGGGAATGGTATTACCCTGCTGTTCCATACCGAGCGGAACATTTCAACTGGCCTCACTGTGTTATTGATGGTTCTGACTACGTCAATGACGCTTTGAGGGTACGCAACTGTGAGCTGGTAGGCTTGAAGGATCTCAATCAAGCTAATGAGCACACCAGAAACATGATTGTCAATTTTATGAACAAACTCATTGACTTAGGTGTCGCCGGATTTAGGATTGACGCAGCAAAACACATGTGGCCTGAGGATCTGCTTATTATTTACAATCGTTTGAACAATCTTAACACTGCCCACGGCTTTCCGTCCAACGCTCGGCCCTACATCTATCAGGAAGTCATTGACTACGGCGGTGAGGCAATCAGTAGGGACGAGTACACTCCTATTGGTGCTGTAACCGAATTCAAGGCCGGCATGGAACTTAGCAGAGCATTCAGAGGGAATAATCAACTTCGTTGGTTATCAAGCTGGGGAACGCAATGGGGCCTTTTAGCCCACAGTGACTCCTTAACTTTTATTGACAATCACGATAACGAAAGGGGACACGGAGGTGGAGGAGGAGTCCTCACGTACAAAGAACCACGTCCATACAAAGCCGCTATCGCTTTCCTACTTGCTCATCCGTACGGAGAGCCCCAGATAATGAGTAGTTTCCTGTTTTGGGATTCAGAGATCGGACCACCTATGGATCATTCGGGAAATATTATATCACCTGCTATCAACTCGGATGGAACCTGCGGTAACGGTTGGGTTTGCCAACACCGCTGGAGACAGATTTACAGCATGGTCGCCTTTAGGAACGTGGCAGGAAACACTGATGTCGTTGAGTGGTGGGATAATGGCAGTAATCAGATTGCCTTCTGTCGAGGCACTAAAGCTTTTATTGCTTTCAATAACGACCGTTGGGACCTTAATCAGAGTTTGCAGACTTGTCTTCCAGCGGGTAGTTACTGCGACGTGATATCTGGCAGTAAAATTGGTAGTTGGTGTCAAGGTAAAACCGTGACTGTTCAGAGCGACGGACGAGCTCAAATTCAAGTGGGTGCCAACGATTATGACATGATGCTGGCCATCCATGTTGGACCCGAGAGTCGCATATGA

Protein

MVKHILLSWLLTLATSVVAYKNPHYVTGRSVNVHLFEWKWNDIADECERFLGPRGFGGIQISPPNENVVLWTYNRPWWERYQPISYELVTRSGNERQFADMVRRCNAAGVRIYVDAVINHMTGEPPENIGTAGNTAVYREWYYPAVPYRAEHFNWPHCVIDGSDYVNDALRVRNCELVGLKDLNQANEHTRNMIVNFMNKLIDLGVAGFRIDAAKHMWPEDLLIIYNRLNNLNTAHGFPSNARPYIYQEVIDYGGEAISRDEYTPIGAVTEFKAGMELSRAFRGNNQLRWLSSWGTQWGLLAHSDSLTFIDNHDNERGHGGGGGVLTYKEPRPYKAAIAFLLAHPYGEPQIMSSFLFWDSEIGPPMDHSGNIISPAINSDGTCGNGWVCQHRWRQIYSMVAFRNVAGNTDVVEWWDNGSNQIAFCRGTKAFIAFNNDRWDLNQSLQTCLPAGSYCDVISGSKIGSWCQGKTVTVQSDGRAQIQVGANDYDMMLAIHVGPESRI

Catalytic Activity

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.

Cofactor

Ca(2+)
chloride

Subunit

Monomer.

Similarity

Belongs to the glycosyl hydrolase 13 family.

Keywords

Calcium   Carbohydrate metabolism   Chloride   Complete proteome   Disulfide bond   Glycosidase   Hydrolase   Metal-binding   Reference proteome   Signal   Polymorphism  

Feature

chain  Alpha-amylase

Uniprot

H9IX93   A0A3G5ARJ9   A0A2A4JNE0   A0A2H1X0X9   A0A0N0PBW1   Q7YXJ4   + More
A0A194QEX4   A0A3S2TT63   A0A212FLR1   B8Y698   A9XTK5   A0A212FJQ5   B1NLD3   A0A0N0PEK4   A0A194Q7A8   Q7YXU5   Q7YXJ3   B1NLD4   F6K706   A0A2A4IUB0   A0A2H1VM91   Q25590   Q8IA46   C7EMF0   H9J6U8   A0A194Q160   Q25592   A0A2A4IVZ7   A0A1I8PGY5   Q25593   W8BSY0   T1P7P3   E5LCR9   A0A1W4VD39   Q24613   A0A1L8EHU5   A0A034VBJ8   A0A0K8W605   A0A1B0GIQ4   A0A1I8JUF9   Q9NKY5   A0A1L2FPB4   Q8MM99   Q8MM80   A0A0A1WIJ1   A0A0A1XMQ5   A0A3G5BII4   Q8N0Q8   Q8N0Q0   A0A1L2FPA6   A0A0P8Y7C4   Q8MY53   Q8N0Q4   Q8N0Q5   Q8N0Q9   Q23834   Q9NKY7   Q9NKY6   Q8MM52   Q24611   Q24610   Q8MY50   Q9NKZ0   Q8N0P6   Q8N0Q7   Q8MLX9   Q9NKZ4   Q8MM40   Q9NKZ1   Q8N0R0   Q8N0Q6   Q8MLY6   Q8MY55   Q8N0Q1   Q8MY49   Q8MY47   Q9GRF6   Q8MY54   Q9N6Q7   O18345   Q8MY52   Q9NKY8   Q9NKY9   Q8N0P8   A0A0A1X493   A0A182T4P5   Q8N0Q2   A0A182V378   Q8MY48   Q8N0Q3   Q23835   A0A3S2LDZ6   Q25591   A0A1L2FPA7   A0A182LFL7   Q27891   Q8MY51   Q24609   Q9NKZ3   A0A0M4ECE3  

EC Number

3.2.1.1

Pubmed

19121390    26354079    22118469    19476481    18314941    18760362    + More
21529256    24495485    25315136    1699840    25348373    10742051    11961101    25830018    30400621    17994087    12136021    11040291    8798339    8536970    9618501    14629045    20966253    7659012   

EMBL

BABH01018101    BABH01018102    BABH01018103    BABH01018104    MG941008    AYV89929.1    + More
NWSH01001047    PCG72932.1    ODYU01012544    SOQ58927.1    KQ460772    KPJ12474.1    AY333761    AAP97393.1    KQ459053    KPJ03969.1    RSAL01000004    RVE54528.1    AGBW02007717    OWR54671.1    FJ489868    ACL14798.1    EF672102    ABV24963.1    AGBW02008240    OWR53975.1    EF600048    ABU98613.1    KQ459761    KPJ20139.1    KQ459580    KPI99290.1    AY330289    AAP92665.1    AY333762    AAP97394.1    EF600049    EU325552    ABU98614.1    ACB54942.1    HM357843    AEA76309.1    NWSH01006767    PCG63259.1    ODYU01003330    SOQ41941.1    U04223    AAA03715.1    AF280891    AAO13754.1    GQ274006    ACT64133.1    BABH01028500    BABH01028501    BABH01028502    KPI99291.1    U04225    AAA03640.1    NWSH01006246    PCG63558.1    U04226    AAA03641.1    GAMC01004278    JAC02278.1    KA644631    AFP59260.1    HQ424576    ADP89000.1    X76241    CAA53820.1    GFDG01000548    JAV18251.1    GAKP01019473    GAKP01019470    JAC39482.1    GDHF01005753    JAI46561.1    AJWK01015266    AJWK01015267    AB035069    BAA95443.1    KX398854    ANZ79223.1    AB077388    AB077395    AB077406    AB077407    BAB91501.1    BAB91508.1    BAB91519.1    BAB91520.1    AB077412    AB077413    AB077417    AB077423    AB077424    BAB91525.1    BAB91526.1    BAB91530.1    BAB91536.1    BAB91537.1    GBXI01015791    JAC98500.1    GBXI01001663    JAD12629.1    MK075190    AYV99593.1    AB077391    BAB91504.1    AB077430    BAB91543.1    KX398852    ANZ79221.1    CH902619    KPU77312.1    AB078767    BAC06333.1    AB077404    BAB91517.1    AB077402    BAB91515.1    AB077390    BAB91503.1    U53477    U31121    AB035065    BAA95439.1    AB035066    BAA95440.1    AB077392    AB077393    AB077394    AB077396    AB077397    AB077403    BAB91505.1    BAB91506.1    BAB91507.1    BAB91509.1    BAB91510.1    BAB91516.1    D21129    BAA04667.1    D21128    BAA04666.1    AB078770    BAC06336.1    AB035062    BAA95436.1    AB077435    BAB91548.1    AB077400    BAB91513.1    AB077419    AB077420    BAB91532.1    BAB91533.1    AB035056    AB077408    AB077414    AB077416    BAA95430.1    BAB91521.1    BAB91527.1    BAB91529.1    AB077409    AB077410    AB077411    AB077415    AB077421    AB077422    AB077425    AB077428    AB077429    BAB91522.1    BAB91523.1    BAB91524.1    BAB91528.1    BAB91534.1    BAB91535.1    BAB91538.1    BAB91541.1    BAB91542.1    AB035061    BAA95435.1    AB077389    BAB91502.1    AB077401    BAB91514.1    AB077398    AB077399    AB077405    BAB91511.1    BAB91512.1    BAB91518.1    AB078765    BAC06331.1    AB077427    BAB91540.1    AB078771    BAC06337.1    AB078773    BAC06339.1    U53478    AAB69330.1    AB078766    BAC06332.1    AB035067    AB035068    BAA95442.1    U53698    CH902617    AF238958    AF238959    AF238960    AF238961    AF238962    AF238963    AF238964    AF238965    AF238966    AF238967    AF238968    AF238969    AF238970    AF238971    AF238972    AF238973    AF238974    AF238975    AF238976    AF238977    AB078768    BAC06334.1    AB035064    BAA95438.1    AB035063    BAA95437.1    AB077433    BAB91546.1    GBXI01008606    JAD05686.1    AB077426    BAB91539.1    AB078772    BAC06338.1    AB077418    BAB91531.1    AF238900    AF238901    AF238902    AF238903    AF238904    AF238905    AF238906    AF238907    AF238908    AF238909    AF238910    AF238911    AF238912    AF238913    AF238914    AF238915    AF238916    AF238917    AF238918    AF238919    AF238920    AF238921    AF238922    AF238923    AF238924    AF238925    AF238926    AF238927    AF238928    AF238929    AF238930    AF238931    AF238932    AF238933    AF238934    AF238935    AF238936    AF238937    AF238938    AF238939    AF238940    AF238941    AF238942    AF238943    AF238944    AF238945    AF238946    AF238947    AF238948    AF238949    AF238950    AF238951    AF238952    AF238953    AF238954    AF238955    AF238956    AF238957    U31122    RSAL01000030    RVE51685.1    U04224    AAA03707.1    KX398853    ANZ79222.1    U20331    U20332    AAC46840.1    AAC46841.1    AB078769    BAC06335.1    X76240    CAA53819.1    AB035059    BAA95433.1    CP012524    ALC40426.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000007151    + More
UP000095300    UP000095301    UP000192221    UP000092461    UP000075900    UP000007801    UP000075901    UP000075903    UP000075882    UP000092553   

PRIDE

H9IX93    C7EMF0    H9J6U8    Q23834    O18345    Q23835    + More

Pfam

PF02806   Alpha-amylase_C        + More
PF00155   Aminotran_1_2
PF00128   Alpha-amylase

Interpro

IPR006047   Glyco_hydro_13_cat_dom        + More
IPR015421   PyrdxlP-dep_Trfase_major       
IPR015424   PyrdxlP-dep_Trfase       
IPR006048   A-amylase/branching_C       
IPR004839   Aminotransferase_I/II       
IPR031319   A-amylase_C       
IPR006046   Alpha_amylase       
IPR001917   Aminotrans_II_pyridoxalP_BS       
IPR013780   Glyco_hydro_b       
IPR015422   PyrdxlP-dep_Trfase_dom1       
IPR017853   Glycoside_hydrolase_SF       

SUPFAM

SSF51445   SSF51445        + More
SSF53383   SSF53383       

Gene 3D

2.60.40.1180     3.40.640.10     3.90.1150.10    

ProteinModelPortal

H9IX93   A0A3G5ARJ9   A0A2A4JNE0   A0A2H1X0X9   A0A0N0PBW1   Q7YXJ4   + More
A0A194QEX4   A0A3S2TT63   A0A212FLR1   B8Y698   A9XTK5   A0A212FJQ5   B1NLD3   A0A0N0PEK4   A0A194Q7A8   Q7YXU5   Q7YXJ3   B1NLD4   F6K706   A0A2A4IUB0   A0A2H1VM91   Q25590   Q8IA46   C7EMF0   H9J6U8   A0A194Q160   Q25592   A0A2A4IVZ7   A0A1I8PGY5   Q25593   W8BSY0   T1P7P3   E5LCR9   A0A1W4VD39   Q24613   A0A1L8EHU5   A0A034VBJ8   A0A0K8W605   A0A1B0GIQ4   A0A1I8JUF9   Q9NKY5   A0A1L2FPB4   Q8MM99   Q8MM80   A0A0A1WIJ1   A0A0A1XMQ5   A0A3G5BII4   Q8N0Q8   Q8N0Q0   A0A1L2FPA6   A0A0P8Y7C4   Q8MY53   Q8N0Q4   Q8N0Q5   Q8N0Q9   Q23834   Q9NKY7   Q9NKY6   Q8MM52   Q24611   Q24610   Q8MY50   Q9NKZ0   Q8N0P6   Q8N0Q7   Q8MLX9   Q9NKZ4   Q8MM40   Q9NKZ1   Q8N0R0   Q8N0Q6   Q8MLY6   Q8MY55   Q8N0Q1   Q8MY49   Q8MY47   Q9GRF6   Q8MY54   Q9N6Q7   O18345   Q8MY52   Q9NKY8   Q9NKY9   Q8N0P8   A0A0A1X493   A0A182T4P5   Q8N0Q2   A0A182V378   Q8MY48   Q8N0Q3   Q23835   A0A3S2LDZ6   Q25591   A0A1L2FPA7   A0A182LFL7   Q27891   Q8MY51   Q24609   Q9NKZ3   A0A0M4ECE3  

PDB

1TMQ     E-value=1.241e-159,     Score=1446

KEGG

101736114    K01176 alpha-amylase [EC:3.2.1.1] | (RefSeq) alpha-amylase 2-like

GO

GO:0103025   GO:0009058   GO:0043169   GO:0016740   GO:0005975   GO:0030170   GO:0004556   GO:0046872   GO:0003824   GO:0003676   GO:0005634   GO:0043565   GO:0003677   GO:0003707   GO:0006418  

SignalP

Position:   1 - 19,         Likelihood:  0.985007

 

 

Length:

503

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.67608

Exp number, first 60 AAs:

1.67198

Total prob of N-in:

0.07838

outside

1  -  503

 

 

Pi

5.408413

Theta

30.566283

Tajima's D

-0.653697

CLR

0.620611

CSRT

0.206189690515474

Interpretation

Uncertain