Gene

KWMTBOMO11390

Pre Gene Modal

BGIBMGA001865

Annotation

PREDICTED:_UDP-glucose_4-epimerase-like_[Bombyx_mori]

Location

Bomo_Chr19(+):4587547-4602120      View in EpiBrowser

Full name

RuvB-like helicase      

Location in the cell

PlasmaMembrane   Reliability : 2.08

CDS

ATGCCGCGATTCAAGAACATATTAGTGACGGGCGGAGCCGGATACATAGGAAGTCATTGCGTAGTCACACTGCTGGAAGCCGGTCATGAGGTCATTGCAATTGACAACTTCACTAACTCGGTAGAAGACGAAGACGGATCCCCAGCTTTACAGAGAGCTGAAAAAATCACGGGAAAGAAGATCACGTTTTACAAGGCTGATTTACTTGATAAACCACAAATCAATGCTATTTTCGACAAGCATCCTGTGGACTGCGTGATCCATTTTGCGGCACTCAAAGCAGTTGGGGAATCGATGCAGCAACCCTTATTATACTACCAGAACAACCTGCTTGGGATGCTCAACTTATTGGAGATAATGCGATCACACAATTGCTACCAAATGGTGTTCTCGTCGTCATGCACAGTCTACGGCGAACCTGAACACTTGCCGATCACGGAGACTCATCCCACTGGAAGTATCACAAATGTTTACGGCAGAACGAAGTACTTCATCGAGGAAATGCTCAAAGACTTAAGCGCTGCTGATGATAAATGGAACATTATCTCCCTCCGGTATTTCAACCCTGTCGGTGCACATCCTTCAGGGCTGATCGGCGAAGACCCTACTAAGGAGTTCACCAACCTCATGCCATTCCTCGCGCAAGTTGCTCTCGGCAAGAAACCTGTGCTCACCGTTTTCGGAACCGACTACAACACTCCCGATGGAACTGGTATTCGAGATTACATACACGTCATGGATTTGGCTAGCGGGCATGTAGCCGCGTTAAATTTACTCAGCCAAACCCATATCAGACTAAAGGTCAGTACGTACGTAAAAATATATATTTATATAGTATATACTCATTTTTTTTTTCATTTTCTTTCTTGTAATCTCAACCTCTAG

Protein

MPRFKNILVTGGAGYIGSHCVVTLLEAGHEVIAIDNFTNSVEDEDGSPALQRAEKITGKKITFYKADLLDKPQINAIFDKHPVDCVIHFAALKAVGESMQQPLLYYQNNLLGMLNLLEIMRSHNCYQMVFSSSCTVYGEPEHLPITETHPTGSITNVYGRTKYFIEEMLKDLSAADDKWNIISLRYFNPVGAHPSGLIGEDPTKEFTNLMPFLAQVALGKKPVLTVFGTDYNTPDGTGIRDYIHVMDLASGHVAALNLLSQTHIRLKVSTYVKIYIYIVYTHFFFHFLSCNLNL

Description

Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

Catalytic Activity

ATP + H2O = ADP + H(+) + phosphate

Cofactor

NAD(+)

Similarity

Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Belongs to the RuvB family.

Uniprot

A0A2A4KAV8   A0A2H1WC29   A0A2I6RJP3   A0A3S2NYE9   S4PFF5   A0A212EIE1   + More
A0A0N1IDE3   A0A194QEM8   A0A2J7R5J0   R4V414   A0A1B6KYY3   A0A2J7R5I0   A0A2J7R5K0   A0A2J7R5I7   A0A2J7R5I8   A0A0P4VJI0   R4G3P1   A0A232EPE2   K7JBZ4   A0A0P5YIA2   A0A0P5K2E9   A0A0V0G9E4   A0A0P5TNH6   A0A0P6GBX9   A0A023F8V3   A0A0P5ZKS8   A0A0P5SHN8   A0A0P5ISC9   A0A0P6G8K7   A0A023ERP8   A0A0P5SYU0   A0A1D2MHD3   A0A0P6DY26   A0A0P5SD13   A0A0P6C2L1   A0A067QWG7   A0A0P5GIF3   E9FXH2   A0A0P6HE18   E0VSA5   A0A088AHU6   Q173X0   B0W2X9   A0A1Q3FRD5   A0A195B6F5   A0A158NH12   E2C0C9   A0A151XDD8   A0A1B6I986   A0A1B6I8L6   A0A1B6I3U4   A0A195FPW4   A0A182IZE4   A0A1B6I0Q5   J9JX18   A0A154PS24   F4WST0   A0A1B6F1N9   A0A026WZG5   A0A0P4WGH7   A0A0P4WPC5   A0A182PJF5   A0A0M9A7A5   A0A0P4WAI4   A0A182NGS2   A0A2S2PCU9   A0A182IBH2   A0A182WFD7   E9IJP3   Q7PPN2   A0A2A3EBC9   A0A182YM82   A0A182UUQ7   A0A2H8TXD6   A0A182TGK7   A0A0J7L496   A0A182M7D0   A0A182QZN4   A0A182X4Y0   A0A1Y1MND7   A0A0K8TTS3   A0A226EGR1   A0A182SXW2   A0A182JSV0   A0A1Y9HDW0   A0A182KN27   D6WRX8   A0A0L7KRA9   A0A423STC5   A0A1L8E3I3   A0A195D1B3   A0A1J1IJC6   A0A182F383   A0A084VJ67   A0A151J1Z9   A0A0A9YSE3   T1J1N4   W5JMK9   A0A0P6F4G0   A0A0P6FTM3  

EC Number

3.6.4.12
5.1.3.-

Pubmed

23622113    22118469    26354079    27129103    28648823    20075255    + More
25474469    24945155    26483478    27289101    24845553    21292972    20566863    17510324    21347285    20798317    21719571    24508170    21282665    12364791    14747013    17210077    25244985    28004739    26369729    20966253    18362917    19820115    26227816    24438588    25401762    26823975    20920257    23761445   

EMBL

NWSH01000016    PCG80792.1    ODYU01007665    SOQ50645.1    KY304475    AUN86406.1    + More
RSAL01000096    RVE47751.1    GAIX01004032    JAA88528.1    AGBW02014672    OWR41248.1    KQ460772    KPJ12453.1    KQ459053    KPJ03993.1    NEVH01006994    PNF36098.1    KC740744    AGM32568.1    GEBQ01023356    JAT16621.1    PNF36095.1    PNF36100.1    PNF36093.1    PNF36097.1    GDKW01001434    JAI55161.1    ACPB03005950    GAHY01001491    JAA76019.1    NNAY01002975    OXU20197.1    AAZX01007055    AAZX01008310    AAZX01012997    AAZX01018359    AAZX01026465    GDIP01057459    JAM46256.1    GDIQ01190624    JAK61101.1    GECL01001587    JAP04537.1    GDIP01141458    JAL62256.1    GDIQ01037011    JAN57726.1    GBBI01000865    JAC17847.1    GDIP01042261    JAM61454.1    GDIQ01104290    JAL47436.1    GDIQ01210367    JAK41358.1    GDIQ01037010    JAN57727.1    JXUM01029814    JXUM01029815    JXUM01029816    JXUM01029817    JXUM01029818    JXUM01029819    JXUM01029820    GAPW01002232    KQ560865    JAC11366.1    KXJ80572.1    GDIP01140307    JAL63407.1    LJIJ01001272    ODM92312.1    GDIQ01070570    JAN24167.1    GDIP01141457    JAL62257.1    GDIP01007838    JAM95877.1    KK853284    KDR08974.1    GDIQ01247500    JAK04225.1    GL732526    EFX88079.1    GDIQ01021344    JAN73393.1    DS235748    EEB16261.1    CH477416    EAT41326.1    DS231829    EDS30338.1    GFDL01004886    JAV30159.1    KQ976574    KYM80098.1    ADTU01015424    GL451770    EFN78588.1    KQ982294    KYQ58330.1    GECU01024276    JAS83430.1    GECU01024425    JAS83281.1    GECU01026099    JAS81607.1    KQ981387    KYN41974.1    GECU01027232    JAS80474.1    ABLF02034425    KQ435119    KZC14716.1    GL888327    EGI62737.1    GECZ01025629    JAS44140.1    KK107063    EZA61218.1    GDRN01074091    JAI63292.1    GDRN01074092    JAI63291.1    KQ435727    KOX77926.1    GDRN01074089    JAI63293.1    GGMR01014650    MBY27269.1    APCN01000690    GL763877    EFZ19222.1    AAAB01008944    EAA10132.4    KZ288310    PBC28602.1    GFXV01007129    MBW18934.1    LBMM01000855    KMQ97363.1    AXCM01012196    AXCN02002201    GEZM01026181    GEZM01026180    JAV87171.1    GDAI01000062    JAI17541.1    LNIX01000004    OXA55856.1    KQ971351    EFA06422.2    JTDY01006863    KOB65635.1    QCYY01002808    ROT67458.1    GFDF01000803    JAV13281.1    KQ976973    KYN06657.1    CVRI01000054    CRK99866.1    ATLV01013473    ATLV01013474    KE524860    KFB38011.1    KQ980447    KYN16005.1    GBHO01007637    GBRD01016746    GDHC01011311    JAG35967.1    JAG49081.1    JAQ07318.1    JH431789    ADMH02001090    ETN64140.1    GDIQ01054022    JAN40715.1    GDIQ01054024    JAN40713.1   

Proteomes

UP000218220    UP000283053    UP000007151    UP000053240    UP000053268    UP000235965    + More
UP000015103    UP000215335    UP000002358    UP000069940    UP000249989    UP000094527    UP000027135    UP000000305    UP000009046    UP000005203    UP000008820    UP000002320    UP000078540    UP000005205    UP000008237    UP000075809    UP000078541    UP000075880    UP000007819    UP000076502    UP000007755    UP000053097    UP000075885    UP000053105    UP000075884    UP000075840    UP000075920    UP000007062    UP000242457    UP000076408    UP000075903    UP000075902    UP000036403    UP000075883    UP000075886    UP000076407    UP000198287    UP000075901    UP000075881    UP000075900    UP000075882    UP000007266    UP000037510    UP000283509    UP000078542    UP000183832    UP000069272    UP000030765    UP000078492    UP000000673   

Pfam

PF16363   GDP_Man_Dehyd        + More
PF17856   TIP49_C
PF06068   TIP49
PF01370   Epimerase
PF12400   STIMATE

Interpro

IPR005886   UDP_G4E        + More
IPR016040   NAD(P)-bd_dom       
IPR036291   NAD(P)-bd_dom_sf       
IPR027238   RuvB-like       
IPR010339   TIP49_P-loop       
IPR027417   P-loop_NTPase       
IPR037942   RUVBL2       
IPR041048   RuvB-like_C       
IPR003593   AAA+_ATPase       
IPR001509   Epimerase_deHydtase       
IPR011990   TPR-like_helical_dom_sf       
IPR022127   STIMATE/YPL162C       

SUPFAM

SSF51735   SSF51735        + More
SSF52540   SSF52540       
SSF48452   SSF48452       

Gene 3D

1.25.40.10    

CDD

cd05247  UDP_G4E_1_SDR_e

ProteinModelPortal

A0A2A4KAV8   A0A2H1WC29   A0A2I6RJP3   A0A3S2NYE9   S4PFF5   A0A212EIE1   + More
A0A0N1IDE3   A0A194QEM8   A0A2J7R5J0   R4V414   A0A1B6KYY3   A0A2J7R5I0   A0A2J7R5K0   A0A2J7R5I7   A0A2J7R5I8   A0A0P4VJI0   R4G3P1   A0A232EPE2   K7JBZ4   A0A0P5YIA2   A0A0P5K2E9   A0A0V0G9E4   A0A0P5TNH6   A0A0P6GBX9   A0A023F8V3   A0A0P5ZKS8   A0A0P5SHN8   A0A0P5ISC9   A0A0P6G8K7   A0A023ERP8   A0A0P5SYU0   A0A1D2MHD3   A0A0P6DY26   A0A0P5SD13   A0A0P6C2L1   A0A067QWG7   A0A0P5GIF3   E9FXH2   A0A0P6HE18   E0VSA5   A0A088AHU6   Q173X0   B0W2X9   A0A1Q3FRD5   A0A195B6F5   A0A158NH12   E2C0C9   A0A151XDD8   A0A1B6I986   A0A1B6I8L6   A0A1B6I3U4   A0A195FPW4   A0A182IZE4   A0A1B6I0Q5   J9JX18   A0A154PS24   F4WST0   A0A1B6F1N9   A0A026WZG5   A0A0P4WGH7   A0A0P4WPC5   A0A182PJF5   A0A0M9A7A5   A0A0P4WAI4   A0A182NGS2   A0A2S2PCU9   A0A182IBH2   A0A182WFD7   E9IJP3   Q7PPN2   A0A2A3EBC9   A0A182YM82   A0A182UUQ7   A0A2H8TXD6   A0A182TGK7   A0A0J7L496   A0A182M7D0   A0A182QZN4   A0A182X4Y0   A0A1Y1MND7   A0A0K8TTS3   A0A226EGR1   A0A182SXW2   A0A182JSV0   A0A1Y9HDW0   A0A182KN27   D6WRX8   A0A0L7KRA9   A0A423STC5   A0A1L8E3I3   A0A195D1B3   A0A1J1IJC6   A0A182F383   A0A084VJ67   A0A151J1Z9   A0A0A9YSE3   T1J1N4   W5JMK9   A0A0P6F4G0   A0A0P6FTM3  

PDB

1HZJ     E-value=7.25167e-80,     Score=755

KEGG

101746316    K01784 UDP-glucose 4-epimerase [EC:5.1.3.2] | (RefSeq) UDP-glucose 4-epimerase-like

PATHWAY

00052    Galactose metabolism - Bombyx mori (domestic silkworm)
00520    Amino sugar and nucleotide sugar metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0003978   GO:0006012   GO:0016853   GO:0006325   GO:0031011   GO:0043141   GO:0005524   GO:0006281   GO:0035267   GO:0097255   GO:0050662   GO:0033499   GO:0019388   GO:0005829   GO:0016021   GO:0003824   GO:0016620   GO:0046034   GO:0032559   GO:0004812   GO:0006418  

PANTHER

PTHR11093   PTHR11093:SF2  

Subcellular location

Nucleus  

Length:

294

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

16.46412

Exp number, first 60 AAs:

1.57597

Total prob of N-in:

0.37408

outside

1  -  294

 

 

Pi

204.703112

Theta

181.730712

Tajima's D

0.451677

CLR

0.18929

CSRT

0.496975151242438

Interpretation

Uncertain