Gene

KWMTBOMO11360

Pre Gene Modal

BGIBMGA001856

Annotation

PREDICTED:_juvenile_hormone_esterase-like_[Amyelois_transitella]

Location

Bomo_Chr19(+):4073314-4076151      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Mitochondrial   Reliability : 1.566 PlasmaMembrane   Reliability : 1.484

CDS

ATGATTGGAAGGAAGCTGTTTACTGTTTTTGATAAGAAGCCTTATGTTGCTTTTTGGGATATATCGTATGCGGAGCCGCCTGTTGGCAATCTCAGATTTAAGCCACCGAAATTACGACTGAATTTTGGCTCCACGAAATTCAATTATAGTAAACCTTACTTGAACACTCGTCGATCAAGAACCGAAGACTGTCTTTACTTATCTATTTATATGCCTTTGACTAATGCCACTGGTTTTCCTGTTATTATTTGGATACACGAGCGTTCATATTGTCATGGACCAGATTTCTTTATTGATGAGAATATTATTGTTGTGACAGTGTCATTCCGTACCGGTATATTTGGATATTTGAACACCGGCGATGGTTTTGCTCTCGGCAATATGGGAGCCAAAGATATGCTTACGGCTATCAAATGGGTGAAAAGTAATATAAAAAATTTTAAAGGCGATGTCGATAAAATCACTGTTATTGGATCCGGTGAAGCGGCTGCTTCTGTAGCTACGTTTCCCCTAACATCTGCAGCGGGAAATTTATTTTCAAGAATAATCGTTGAGAGCGGCAGCGCTTTATCGCCTGAAAATTATAGAAATTACAATTTCGAGATCTCAAACAAGCTGTACTGGAATCTTAATGGTCCATTCAAAAAGTTGAATAGAACTAATTTATACCAAATCCTCGCTAATTCGACCACGAATGAATTGTTATTGGCGTCCGGAGCGCTATTTGACAGTACCGAAGTGAGAGATAATCAGAGGCTAATTAATTCCTTTGGACCGACAGTTGAATTGTCGGGGAAGGGCGCTTTTATGAATAAATTTCCATCGGACATATACAAGCGACCCCTTCCTAATAAGAGCGTTGATGTGATGTTCGGCTATACAAGTTTGGAATATCTTCATAAGCTCCGAGGCTTTGTGGATAACAGAAAACTTTTAAAGTTTATGAATTACAATTTTCAGTACCTTGTGCCTTTTGAGGGTAAGATAGACGAGTATGGATCGAAACGTTATCAAGAGATACGTCAGAGAATAATGGATTTCTATTTCGCGAACGGAACTATTGGCGAAAGGAGTTTAAGGCGATACGCAAAATACGTATCGGATCAAGCGATTTATCCTGTAATACGCCAGGCCAGATCACACTCAGAAAAGTCGGGTAATAATGTTTACTTATACAGATTCTCGTATAAAGGTTGTTTGAACATCGTTCGAGATTTGCTCCTCCGAAATTTTAAGTTGACTGGAGCGACTGGAGGGGACGAGGTTTGTTACCAATTCACATGCAAATCAGCGAACCGGCTCTACAGAAGCGAGGTGTCGAGTGAAAGGAGGTTCGTTAAGAAGATTGCGAGGCTATTGGCGAACTTCGCTAAGCATGGGGACCCAACGCCGGAGGGCAGCGATGAGATTCTGGGCGACTTAAAATGGACGCCAATGGTCGATCTCAATAATATCAAAGGGTTAAATTTGAATCGAAAAATTAAAATGATCGAATTACCCGAAATGAGGAGAGTAAGGTTTTGGGATCAATTGAAGAGCGAATATTTTGAAGATTTCGATTAA

Protein

MIGRKLFTVFDKKPYVAFWDISYAEPPVGNLRFKPPKLRLNFGSTKFNYSKPYLNTRRSRTEDCLYLSIYMPLTNATGFPVIIWIHERSYCHGPDFFIDENIIVVTVSFRTGIFGYLNTGDGFALGNMGAKDMLTAIKWVKSNIKNFKGDVDKITVIGSGEAAASVATFPLTSAAGNLFSRIIVESGSALSPENYRNYNFEISNKLYWNLNGPFKKLNRTNLYQILANSTTNELLLASGALFDSTEVRDNQRLINSFGPTVELSGKGAFMNKFPSDIYKRPLPNKSVDVMFGYTSLEYLHKLRGFVDNRKLLKFMNYNFQYLVPFEGKIDEYGSKRYQEIRQRIMDFYFANGTIGERSLRRYAKYVSDQAIYPVIRQARSHSEKSGNNVYLYRFSYKGCLNIVRDLLLRNFKLTGATGGDEVCYQFTCKSANRLYRSEVSSERRFVKKIARLLANFAKHGDPTPEGSDEILGDLKWTPMVDLNNIKGLNLNRKIKMIELPEMRRVRFWDQLKSEYFEDFD

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

A0A2W1BL22   A0A2A4IXA7   A0A437BBC7   A0A0L7KWE0   A0A194QEW3   A0A0L7LQI3   + More
A0A2W1B5B7   A0A212EGJ1   A0A1L8D6N1   A0A2S0E4A0   A0A194PEZ8   A0A194QS43   A0A2A4IWX2   A0A212FG61   A0A0C5K9J4   A0A212FG55   W8EFW5   A0A194PFX4   A0A212EZ22   A0A194RA61   A0A1U9X1W4   A0A437BI15   A0A2W1BSN7   A0A3S2NSX5   B2BNZ1   A0A2A4J4W9   A0A1J1IUN8   A0A2H1WPZ4   A0A194QKN3   A0A0C5KNY6   A0A182PZ50   B4NJK8   A0A2W1BNC3   A0A1U9X1Z2   A0A2A4IYB2   A0A0K8URL8   A0A194RAU5   A0A034VR46   A0A068F517   A0A182QA60   A0A0C5K2R4   A0A182MC67   A0A0M5J219   A0A1I8PWQ3   A0A1I8PWP1   A0A0R1E4Y1   A0A182IVR5   A0A1I8PWQ1   A0A2J7RMP3   D5G3F8   A0A437BBD5   A0A1W6L1F0   A0A1I8PWR0   A0A0B4RXU8   A0A1U9X1X2   A0A2A4IXT2   B4KA74   A0A2H1WR02   B4PN92   A0A0L7KWA4   B4M0S0   B4JRH5   A0A0Q9WRN5   A0A194RFL8   A0A0Q9XCP6   B3LY87   A0A0Q9WFF2   A0A0R1E9H0   Q171Y4   A0A1I8PWN8   B3P7B4   A0A182XUK3   A0A2H1WPM7   A0A1W4URD4   A0A1W4V4P9   D5G3F9   A0A2J7RMN7   K7IN31   A0A1A9X418   A0A1W4URC9   A0A139WFP4   A0A182TQH1   A0A182UWV7   A0A2C9H8H2   A0A2C9GQP3   Q7PY29   A0A1Y1MG78   A0A182UGI7   A0A2J7RMU7   A0A0L0CLK8   Q4JSA3   A0A2W1BL56   A0A1I8PWQ5   W8BIG0   A0A2Z4HPS6   A0A182VZM5   A0A2Z4HPR2   Q17G40  

EC Number

3.1.1.-

Pubmed

28756777    26227816    26354079    22118469    29149030    18651917    + More
17994087    25348373    25880816    17550304    20005949    18057021    17510324    20075255    18362917    19820115    12364791    14747013    17210077    28004739    26108605    15944077    24495485   

EMBL

KZ149982    PZC75772.1    NWSH01005083    PCG64455.1    RSAL01000096    RVE47729.1    + More
JTDY01004957    KOB67553.1    KQ459053    KPJ04017.1    JTDY01000333    KOB77659.1    KZ150310    PZC71462.1    AGBW02015069    OWR40592.1    GEYN01000028    JAV02101.1    KY997071    ATY49611.1    KQ459605    KPI91941.1    KQ461196    KPJ06361.1    PCG64457.1    AGBW02008712    OWR52719.1    KP114637    AJP62549.1    OWR52721.1    KF849360    AHJ81323.1    KQ459604    KPI92286.1    AGBW02011379    OWR46748.1    KQ460436    KPJ14728.1    KY021853    AQY62742.1    RSAL01000053    RVE50094.1    PZC75770.1    RVE47728.1    EF591058    ABU88425.1    NWSH01003327    PCG66554.1    CVRI01000059    CRL03418.1    ODYU01010136    SOQ55032.1    KPJ04016.1    KP114634    AJP62546.1    CH964272    EDW83932.2    PZC75771.1    KY021886    AQY62775.1    PCG64456.1    GDHF01023319    GDHF01018887    GDHF01001753    JAI28995.1    JAI33427.1    JAI50561.1    KPJ14727.1    GAKP01013206    JAC45746.1    KJ702184    AID61338.1    AXCN02000324    KP114630    AJP62542.1    AXCM01000026    CP012526    ALC46936.1    CM000160    KRK04137.1    NEVH01002552    PNF42100.1    FJ997322    ADF43487.1    RVE47727.1    KX609462    ARN17869.1    KJ023247    AIY69075.1    KY021870    AQY62759.1    PCG64459.1    CH933806    EDW16749.1    KRG02287.1    ODYU01010411    SOQ55495.1    EDW98147.2    KOB67552.1    CH940650    EDW67362.1    CH916373    EDV94365.1    KRF83259.1    KPJ14726.1    KRG02286.1    CH902617    EDV43991.2    KRF83261.1    KRK04138.1    CH477443    EAT40802.2    CH954182    EDV54003.1    SOQ55031.1    FJ997323    ADF43488.1    PNF42088.1    KQ971352    KYB26709.1    APCN01000909    AAAB01008987    EAA00872.4    GEZM01035172    JAV83375.1    PNF42157.1    JRES01000232    KNC33141.1    CR954257    CAJ14159.1    PZC75769.1    GAMC01013509    JAB93046.1    MF163418    AWW17120.1    MF163421    AWW17123.1    CH477266    EAT45545.1   

Proteomes

UP000218220    UP000283053    UP000037510    UP000053268    UP000007151    UP000053240    + More
UP000183832    UP000075885    UP000007798    UP000075886    UP000075883    UP000092553    UP000095300    UP000002282    UP000075880    UP000235965    UP000009192    UP000008792    UP000001070    UP000007801    UP000008820    UP000008711    UP000076407    UP000192221    UP000002358    UP000091820    UP000007266    UP000075902    UP000075903    UP000075840    UP000007062    UP000037069    UP000075920   

Pfam

PF00135   COesterase        + More
PF00083   Sugar_tr
PF00067   p450

Interpro

IPR019819   Carboxylesterase_B_CS        + More
IPR002018   CarbesteraseB       
IPR029058   AB_hydrolase       
IPR019826   Carboxylesterase_B_AS       
IPR002168   Lipase_GDXG_HIS_AS       
IPR000997   Cholinesterase       
IPR005829   Sugar_transporter_CS       
IPR020846   MFS_dom       
IPR036259   MFS_trans_sf       
IPR005828   MFS_sugar_transport-like       
IPR001128   Cyt_P450       
IPR017972   Cyt_P450_CS       
IPR002401   Cyt_P450_E_grp-I       
IPR036396   Cyt_P450_sf       

SUPFAM

SSF53474   SSF53474        + More
SSF103473   SSF103473       
SSF48264   SSF48264       

Gene 3D

3.40.50.1820     1.10.630.10    

CDD

cd06174  MFS

ProteinModelPortal

A0A2W1BL22   A0A2A4IXA7   A0A437BBC7   A0A0L7KWE0   A0A194QEW3   A0A0L7LQI3   + More
A0A2W1B5B7   A0A212EGJ1   A0A1L8D6N1   A0A2S0E4A0   A0A194PEZ8   A0A194QS43   A0A2A4IWX2   A0A212FG61   A0A0C5K9J4   A0A212FG55   W8EFW5   A0A194PFX4   A0A212EZ22   A0A194RA61   A0A1U9X1W4   A0A437BI15   A0A2W1BSN7   A0A3S2NSX5   B2BNZ1   A0A2A4J4W9   A0A1J1IUN8   A0A2H1WPZ4   A0A194QKN3   A0A0C5KNY6   A0A182PZ50   B4NJK8   A0A2W1BNC3   A0A1U9X1Z2   A0A2A4IYB2   A0A0K8URL8   A0A194RAU5   A0A034VR46   A0A068F517   A0A182QA60   A0A0C5K2R4   A0A182MC67   A0A0M5J219   A0A1I8PWQ3   A0A1I8PWP1   A0A0R1E4Y1   A0A182IVR5   A0A1I8PWQ1   A0A2J7RMP3   D5G3F8   A0A437BBD5   A0A1W6L1F0   A0A1I8PWR0   A0A0B4RXU8   A0A1U9X1X2   A0A2A4IXT2   B4KA74   A0A2H1WR02   B4PN92   A0A0L7KWA4   B4M0S0   B4JRH5   A0A0Q9WRN5   A0A194RFL8   A0A0Q9XCP6   B3LY87   A0A0Q9WFF2   A0A0R1E9H0   Q171Y4   A0A1I8PWN8   B3P7B4   A0A182XUK3   A0A2H1WPM7   A0A1W4URD4   A0A1W4V4P9   D5G3F9   A0A2J7RMN7   K7IN31   A0A1A9X418   A0A1W4URC9   A0A139WFP4   A0A182TQH1   A0A182UWV7   A0A2C9H8H2   A0A2C9GQP3   Q7PY29   A0A1Y1MG78   A0A182UGI7   A0A2J7RMU7   A0A0L0CLK8   Q4JSA3   A0A2W1BL56   A0A1I8PWQ5   W8BIG0   A0A2Z4HPS6   A0A182VZM5   A0A2Z4HPR2   Q17G40  

PDB

5TYM     E-value=2.93114e-42,     Score=434

KEGG

101735628    K01044 carboxylesterase 1 [EC:3.1.1.1] | (RefSeq) putative inactive carboxylesterase 4

PATHWAY

00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)

GO

GO:0016787   GO:0016021   GO:0004104   GO:0005615   GO:0022857   GO:0052689   GO:0016705   GO:0005506   GO:0020037  

Length:

520

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

15.63981

Exp number, first 60 AAs:

0.01263

Total prob of N-in:

0.60543

outside

1  -  520

 

 

Pi

119.523232

Theta

112.246213

Tajima's D

0.114198

CLR

42.28219

CSRT

0.4002799860007

Interpretation

Uncertain