Gene

KWMTBOMO11342

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr19(-):3779103-3782514      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.47 Nuclear   Reliability : 2.165

CDS

ATGGCGCAAAACGCTAGAGAGAAACCATATTCCCTTACGTTAGCATTCTACAATGCTAACGGACTCGCGCGACAACGCGATCAAATTTACGAATTCCTCCGCGACAAACTTGTAGATATTCTGCTAGTGCAGGAGACCTGCCTGAAGCCCTCGCGTCGTGACCCGAAAGTCGCGAATTACGTCATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGACTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACCCCCTCGCTCTCACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTTCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCCGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCACAGTTCAAACATAAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTTACCTTTGAAGTAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCACTGCTGAGGAACGTAACTCTGCGCTTGCGTTCCATCGAAGCAATGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCCCACAACCCAGTCACAGCTACGAGGACCATGGTGGACTGGAAGAAGCTGGGCAAATGCTTAGCCGATGCCGCTCCACCAATCCTCCCCTGCGGCCCGGATTCAACTCCATCCCCCGAGGACACAGTCGAATCCATAAACATCATCACGGATCACATCTCTTCCGCGATCATAAGATCCTCAAAAGAAGTCGATGTGGAGGATAGCTTCCACCGCATCAGACTGTCCCCCGAACTTAGGAACCTCCTAAGAGTTAGAAACGCGGCAATCCGGGCCTACGATCAACTTCCCACGCACTCAAACCGGATTCGGATGCGTCGTCTACAGCGGGATGTAAAATCTCGCCTAAGCGACGCCCGAAATGAGAATTGGGATAGTTACTTAGAAGGACTCGCGCCCTCTCATCAAGCATACTGGCGACTAGCAAGGACTCTCAAGTCCGAAACTACCGCTACTATGCCTCCTCTCGTACGCCCTTCAGGCCAACCACCGGCTTTCGATGACGATGACAAGGCAGAGTTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAATACGCGGACCCCGAACAGACCGAGGCAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCACCCTCGGACGCGTTACCCCCCATTACCTCTGACGAAGTTAGAGAAGTAATAGACAACCTTCAACCTAAGAAGGCACCCGGCTCCGACGGCATCCGCAACCGCGCGTTAAAACTCTTACCAGTCCAACTGATAACAATGTTGGCTACCATCTTAAATGCCGCTATGACGCACTGCATCTTTCCGGCGGTATGGAAAGAAGCAGACGTTATCGGTATACACAAGCCGGGCAAACCGAATAATGAAACCGCTAGTTACCGACCGATTAGTCTCCTCCCAGCGATAGGCAAAATTTACGAACGGCTCCTTCGGAAACGCCTCTGGGACTTCGTTACCGCGAATAAAATTCTAATAGACGAGCAGTTTGGATTCCGCGCCAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATCTTAATAGGGCTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTTTTCGATGTAGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTGATCTACAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTTGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCATCTGACTGCCGGAGTCCCGCAAGGCTCCGCACTCTCCCCGTTACTATTTAGTTTGTATATCAACGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGAAAGATGTCGTTGCTTCATCGGCGACTCCAGACCGCAGTAACCACCATGGGACAGTGGTTCCGGAAGTGGCGAATAGACATTAACCCCACGAAAAGCACAGCGGTGCTATTCAAAAGGGGTCGCCCTCCGAATACCACTTCGAGCACCCCACTCCCCAATAGGCGCGTAAACACCTCCGCCGTTAGCCCCATCACTCTCTTTGACCAGCCCATACCGTGGGCCCCGAAGGTCAAATACCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCACGTAAAAACGGTACGCGATCGCGCCGCGTTTATACTAGGACGACTCTACCCAATGCTTTGTAGACGAAGCAAACTGTCCCTCCGTAATAAGGTAACCCTCTACAAAACTTGCATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACGCGGCCCGCACCAACTTGAAACCCCTTCAGGTTATACAATCCCGATTCTGCAGGATAGCCGTCGGAGCACCATGGTTCCAGAGGAACGTGGACCTCCACGATGACCTGGAGCTCGACCCCGTCAGTAAGTATCTACAGTCGGCATCGCTGCGCCACTTTGAGAAGGCGGCACGACATGAGAACCCTCTTGTCGTGGCCGCCGGAAACTACATACCCGATCCTGTAGACCGTTTGGGAAAGCAACATGGGCTGATACTCTGGGATCTTCGATAG

Protein

MAQNAREKPYSLTLAFYNANGLARQRDQIYEFLRDKLVDILLVQETCLKPSRRDPKVANYVMVRNDRLTASKGGTAIYYRRALHVVPLDTPSLSHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHSSNINGRRLDAFIDDLTFEVVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPHNPVTATRTMVDWKKLGKCLADAAPPILPCGPDSTPSPEDTVESINIITDHISSAIIRSSKEVDVEDSFHRIRLSPELRNLLRVRNAAIRAYDQLPTHSNRIRMRRLQRDVKSRLSDARNENWDSYLEGLAPSHQAYWRLARTLKSETTATMPPLVRPSGQPPAFDDDDKAELLADALQEQCTTSTQYADPEQTEAVDREVERRASLPPSDALPPITSDEVREVIDNLQPKKAPGSDGIRNRALKLLPVQLITMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPNNETASYRPISLLPAIGKIYERLLRKRLWDFVTANKILIDEQFGFRAKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDVAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFLSNRSFRYRVEGTRSRPRHLTAGVPQGSALSPLLFSLYINDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQTAVTTMGQWFRKWRIDINPTKSTAVLFKRGRPPNTTSSTPLPNRRVNTSAVSPITLFDQPIPWAPKVKYLGVTLDRGMTFRPHVKTVRDRAAFILGRLYPMLCRRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAARTNLKPLQVIQSRFCRIAVGAPWFQRNVDLHDDLELDPVSKYLQSASLRHFEKAARHENPLVVAAGNYIPDPVDRLGKQHGLILWDLR

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   A0A2S2PPK8   X1WLB2   A0A2S2Q383   D7EM17   Q07995   A0A3N5Z7I3   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A087UGF5   A0A2S2QEE0   A0A2J7R7D0   X1WNI2   A0A2M4CV52   A0A2M4CV42   A0A224XF24   A0A224X6S1   A0A224X6Q4   A0A2M4BD67   A0A2M4BDV6   A0A224X6T4   A0A2J7QR37   A0A2J7PU96   A0A2S2NGV8   A0A2J7PBY3   A0A2J7QY69   J9LFC9   J9LC21   A0A224XB44   A0A224X6R6   A0A224X6U5   X1WQI9   X1WZH0   A0A224XI99   A0A2J7Q6J2   A0A2S2N814   A0A2H8TF37   A0A069DZL8   A0A2J7QB68   A0A069DX78   A0A224X6W2   J9M522   J9KKL3   A0A2M4BEF4   A0A2M4BEZ9   A0A2J7PVX3   A0A2S2P698   A0A2A4IUM2   A0A0A9YJ00   A0A2S2R9D4   A0A2S2PJG2   A0A0A9YU04   A0A0V0G5B6   A0A2S2NPG3   A0A1Y1LKN6   A0A224XJI0   A0A224XHW8   A0A1Y1KFR3   A0A2J7PDM0   Q95SX7   Q8I7P8   A0A352X8G4   P21328   K7IN67   A0A2S2PA10   A0A2M4CVF1   A0A2H8TKI9   A0A2S2PHL7   A0A2S2N6Q7   A0A2M4CVK2   D7GYA5   A0A2S2P6S3   A0A0A9YSX4   A0A2S2NH02   P21329   A0A2J7Q0S7   A0A2J7RE85   A0A023F0I3   J9KLB1   A0A1W7R682   A0A1B6EGD8   A0A2J7PQB5   A0A2S2P6C4  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    8387152    30086797    26334808    25401762    7753626    12537569    30148503    2463954    3040362    1714378    20075255    1701254   

EMBL

U07847    AAA17752.1    AB055391    BAB21761.1    AB018558    BAA76304.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    KQ973342    KXZ75569.1    KQ971729    KYB24751.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GBBI01004395    JAC14317.1    GBBI01004571    JAC14141.1    GGMR01018716    MBY31335.1    ABLF02042518    ABLF02057746    GGMS01002992    MBY72195.1    KQ973412    EFA12510.2    S59870    AAB26437.2    RPOV01000134    RPJ78669.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    KK119692    KFM76444.1    GGMS01006359    MBY75562.1    NEVH01006736    PNF36716.1    ABLF02008153    ABLF02008462    ABLF02008464    GGFL01004957    MBW69135.1    GGFL01005012    MBW69190.1    GFTR01008038    JAW08388.1    GFTR01008271    JAW08155.1    GFTR01008279    JAW08147.1    GGFJ01001858    MBW50999.1    GGFJ01001857    MBW50998.1    GFTR01008261    JAW08165.1    NEVH01011985    PNF31054.1    NEVH01021205    PNF19912.1    GGMR01003407    MBY16026.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    ABLF02023911    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    GFTR01008262    JAW08164.1    GFTR01008269    JAW08157.1    GFTR01008251    JAW08175.1    ABLF02022418    ABLF02034467    GFTR01008256    JAW08170.1    NEVH01017470    PNF24199.1    GGMR01000676    MBY13295.1    GFXV01000908    MBW12713.1    GBGD01000415    JAC88474.1    NEVH01016302    PNF25823.1    GBGD01000389    JAC88500.1    GFTR01008260    JAW08166.1    ABLF02024246    ABLF02029306    ABLF02029314    ABLF02060138    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    NEVH01020940    PNF20481.1    GGMR01012305    MBY24924.1    NWSH01007753    PCG62823.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GGMS01017365    MBY86568.1    GGMR01016905    MBY29524.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GECL01003538    JAP02586.1    GGMR01006408    MBY19027.1    GEZM01053022    JAV74219.1    GFTR01008257    JAW08169.1    GFTR01008254    JAW08172.1    GEZM01084969    JAV60363.1    NEVH01026386    PNF14434.1    AY060438    AAL25477.1    AY180919    AAN87272.1    DNOY01000259    HBE18313.1    M22874    M38643    GGMR01013409    MBY26028.1    GGFL01005122    MBW69300.1    GFXV01002840    MBW14645.1    GGMR01016296    MBY28915.1    GGMR01000226    MBY12845.1    GGFL01005121    MBW69299.1    KQ973363    EFA13335.2    GGMR01012443    MBY25062.1    GBHO01008295    JAG35309.1    GGMR01003864    MBY16483.1    M38437    NEVH01019963    PNF22185.1    NEVH01005277    PNF39135.1    GBBI01003747    JAC14965.1    ABLF02040174    ABLF02040183    ABLF02055266    GEHC01000968    JAV46677.1    GEDC01000337    JAS36961.1    NEVH01022639    PNF18527.1    GGMR01012283    MBY24902.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000054359    UP000235965    UP000218220    + More
UP000002358   

PRIDE

Q93137    Q9BPQ0    Q9XXW0    Q95SX7    Q8I7P8    P21328    + More
P21329   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9BPQ0   Q9XXW0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
A0A139W8G9   A0A139WA11   V5GNJ2   V5GNF3   A0A023EYS8   A0A023EZE6   A0A2S2PPK8   X1WLB2   A0A2S2Q383   D7EM17   Q07995   A0A3N5Z7I3   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A087UGF5   A0A2S2QEE0   A0A2J7R7D0   X1WNI2   A0A2M4CV52   A0A2M4CV42   A0A224XF24   A0A224X6S1   A0A224X6Q4   A0A2M4BD67   A0A2M4BDV6   A0A224X6T4   A0A2J7QR37   A0A2J7PU96   A0A2S2NGV8   A0A2J7PBY3   A0A2J7QY69   J9LFC9   J9LC21   A0A224XB44   A0A224X6R6   A0A224X6U5   X1WQI9   X1WZH0   A0A224XI99   A0A2J7Q6J2   A0A2S2N814   A0A2H8TF37   A0A069DZL8   A0A2J7QB68   A0A069DX78   A0A224X6W2   J9M522   J9KKL3   A0A2M4BEF4   A0A2M4BEZ9   A0A2J7PVX3   A0A2S2P698   A0A2A4IUM2   A0A0A9YJ00   A0A2S2R9D4   A0A2S2PJG2   A0A0A9YU04   A0A0V0G5B6   A0A2S2NPG3   A0A1Y1LKN6   A0A224XJI0   A0A224XHW8   A0A1Y1KFR3   A0A2J7PDM0   Q95SX7   Q8I7P8   A0A352X8G4   P21328   K7IN67   A0A2S2PA10   A0A2M4CVF1   A0A2H8TKI9   A0A2S2PHL7   A0A2S2N6Q7   A0A2M4CVK2   D7GYA5   A0A2S2P6S3   A0A0A9YSX4   A0A2S2NH02   P21329   A0A2J7Q0S7   A0A2J7RE85   A0A023F0I3   J9KLB1   A0A1W7R682   A0A1B6EGD8   A0A2J7PQB5   A0A2S2P6C4  

PDB

6AR3     E-value=0.0182713,     Score=93

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313   GO:0008270   GO:0003676  

Length:

927

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.311990000000001

Exp number, first 60 AAs:

0.00136

Total prob of N-in:

0.00578

outside

1  -  927

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

18.139745

CSRT

0

Interpretation

Uncertain