Gene

KWMTBOMO11332  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001976

Annotation

PREDICTED:_hemocyte_protein-glutamine_gamma-glutamyltransferase-like_[Amyelois_transitella]

Location

Bomo_Chr19(-):3445734-3451680      View in EpiBrowser

Full name

Hemocyte protein-glutamine gamma-glutamyltransferase      

Alternative Name

Hemocyte transglutaminase

Location in the cell

Cytoplasmic   Reliability : 1.602

CDS

ATGGTGCTGACGAAGAAGCCGTTCGTGTTTGACCCGATCGGCGATGAAGACCGGGAAGACATCACCAGCCAGTACAAATACAAAGAAGGCACGGCTTCAGAGAGGCTGGCCCTGATGAACGGAGTCAGATATTCGGAGAGAGCGAAGAGGTACTACTCAGTAGTGAGCAACTTACAGACGGACGTGACCTTCAAACTAAGAGACATCGATTTAGTTTCCATCGGCAAAGACTTCAAGGTCACAATCGACATCAAGAATGTTTCGGATCAGGGACGTAACATAAAGGCATCATTGAGCGCATCGAGTTTCTACTACAACGGAGTTAAATTTGACATCATCAAAAAAATCGAAGGAAAACTCTACGTTGGACCACAGAAAAACGAAGAAGTCAGCCTCGTGGTGAAAGTAGAGGACTATTTGCCGAAGCTGGTGGAGTACGGGAACATCAAGATATCTGCGATGGCCATTGTCGATGAAACGAAGCAGTCCTGGGCTGACGACGACGACTTCCAGATCCTCAAACCGAACATTAACATTAAGTTCAAAGACGACCTGATCATCGGGCAGCCGGCAACAGTGGAACTGTCGCTTTTGAACCCTCTGAACAGTACGCTGAGTGGGTGCGAGTTCCGCGTGACGTCATCGGGAATAGCGGGTCGTGCCCTGCGCGTTCCCGCCGCGGACGTCGCTCCTGAAGGACTACTCACCGTTGAACTACCTATTCAACCTAACAAACTGGGTAATATCAGTTTCGTGGCCACATTCAAGTCGAACGAGCTGAAGGACATCAACGGAGCCGCCACCACGGAAGTGCTCGAAGGGTAA

Protein

MVLTKKPFVFDPIGDEDREDITSQYKYKEGTASERLALMNGVRYSERAKRYYSVVSNLQTDVTFKLRDIDLVSIGKDFKVTIDIKNVSDQGRNIKASLSASSFYYNGVKFDIIKKIEGKLYVGPQKNEEVSLVVKVEDYLPKLVEYGNIKISAMAIVDETKQSWADDDDFQILKPNINIKFKDDLIIGQPATVELSLLNPLNSTLSGCEFRVTSSGIAGRALRVPAADVAPEGLLTVELPIQPNKLGNISFVATFKSNELKDINGAATTEVLEG

Catalytic Activity

L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4(+)

Cofactor

Ca(2+)

Similarity

Belongs to the transglutaminase superfamily. Transglutaminase family.

Keywords

Acyltransferase   Calcium   Direct protein sequencing   Membrane   Metal-binding   Transferase  

Feature

chain  Hemocyte protein-glutamine gamma-glutamyltransferase

Uniprot

H9IXJ3   A0A3S2LTZ0   A0A2W1BNN0   A0A212FNQ8   A0A194R102   A0A194QFA5   + More
A0A2H1W2Z2   A0A0L7KZY8   A0A0J7KRL0   A0A2J7PV97   F4WRW8   A0A195FLR1   A0A151XIU9   A0A195BZU0   A0A158NEJ8   E2AYU1   E9ID81   A0A195BUU7   A0A154P0F6   E2B2K7   A0A0L7RFM3   A0A026WXV5   A0A3L8DGG8   A0A0M9A5H6   A0A310SIN2   A0A2A3ERM9   A0A088AKR6   A0A067RI89   A0A0C9QRW2   A0A1Y1KRA9   D6WH00   A0A1B6EUM3   A0A1Y1KS20   A0A1B6D4M4   A0A1W4WI76   A0A1B6KC33   A0A195EN57   A0A2P8YH94   A0A0P5LX05   A0A0P4XT55   A0A0N8C9J7   A0A0P5V592   A0A0P5B761   E9FR81   A0A0P5VIZ2   A0A162DAJ7   A0A0P6DKR4   A0A0P5WA68   A0A0P5XBZ4   A0A0N8AAG4   A0A0P6C2U9   A0A1B6I894   A0A0P5VMP7   A0A1B6K5T3   A0A023EZ45   A0A0P5ML04   Q05187   A0A224XJ93   A0A0V0G4Q1   A0A023F0E9   A0A0V0G7A9   A0A1B6H930   A0A2P2HW15   T1HFS7   A0A224XI60   A0A1D2N8Q4   A0A023EZ44   A0A0V0G6K0   T1J480   A0A0P6IF44   A0A2P6L0I5   A0A023FM45   T1I8S6   A0A023F227   A0A3R7SJE1   A0A2J7QXL3   T1HFP9   A0A224XFQ6   A0A0K8TIJ3   A0A146LM26   A0A0M3LC01   A0A1E1X9T3   A0A0A9WHI8   A0A444SNA9   A0A131Y2F0   A0A147BWD1   A0A444ST60   B7PSF8   A0A131XKN6   A0A0K2TPI8   A0A0K2TRC0   A0A131YNM1   T1HFV3   A3DT47   A0A023GNS4   A0A087T1V1   A0A212ESV0   A0A224YZS7  

EC Number

2.3.2.13

Pubmed

19121390    28756777    22118469    26354079    26227816    21719571    + More
21347285    20798317    21282665    24508170    30249741    24845553    28004739    18362917    19820115    29403074    21292972    25474469    8093243    27289101    26823975    28503490    25401762    29652888    28049606    26830274    17218114    28797301   

EMBL

BABH01018249    RSAL01000205    RVE44370.1    KZ150054    PZC74340.1    AGBW02004770    + More
OWR55378.1    KQ461073    KPJ09521.1    KQ459053    KPJ04094.1    ODYU01006003    SOQ47465.1    JTDY01004110    KOB68589.1    LBMM01004039    KMQ92874.1    NEVH01020980    PNF20253.1    GL888292    EGI63125.1    KQ981490    KYN41187.1    KQ982080    KYQ60333.1    KQ978501    KYM93428.1    ADTU01013469    GL444002    EFN61386.1    GL762454    EFZ21401.1    KQ976401    KYM92394.1    KQ434791    KZC05406.1    GL445147    EFN90084.1    KQ414599    KOC69777.1    KK107064    EZA60872.1    QOIP01000008    RLU19411.1    KQ435750    KOX76269.1    KQ765323    OAD53974.1    KZ288195    PBC33779.1    KK852496    KDR22723.1    GBYB01003366    GBYB01003367    JAG73133.1    JAG73134.1    GEZM01080273    JAV62235.1    KQ971321    EFA00611.1    GECZ01028113    JAS41656.1    GEZM01080272    JAV62236.1    GEDC01016678    JAS20620.1    GEBQ01031002    JAT08975.1    KQ978625    KYN29601.1    PYGN01000598    PSN43603.1    GDIQ01172949    JAK78776.1    GDIP01238123    JAI85278.1    GDIQ01101483    JAL50243.1    GDIP01104828    JAL98886.1    GDIP01188523    JAJ34879.1    GL732523    EFX90239.1    GDIP01099331    JAM04384.1    LRGB01002121    KZS09124.1    GDIQ01090929    JAN03808.1    GDIP01089547    JAM14168.1    GDIP01074345    JAM29370.1    GDIP01166625    JAJ56777.1    GDIP01021961    JAM81754.1    GECU01024577    JAS83129.1    GDIP01097945    JAM05770.1    GECU01000901    JAT06806.1    GBBI01004224    JAC14488.1    GDIQ01162160    JAK89565.1    D12593    GFTR01007764    JAW08662.1    GECL01003105    JAP03019.1    GBBI01004283    JAC14429.1    GECL01002238    JAP03886.1    GECU01036546    JAS71160.1    IACF01000182    LAB65985.1    ACPB03003823    GFTR01006928    JAW09498.1    LJIJ01000150    ODN01465.1    GBBI01004225    JAC14487.1    GECL01002393    JAP03731.1    JH431841    GDIQ01005478    JAN89259.1    MWRG01002934    PRD32083.1    GBBK01002203    JAC22279.1    ACPB03014010    GBBI01003591    JAC15121.1    QCYY01003436    ROT63475.1    NEVH01009379    PNF33318.1    GFTR01007788    JAW08638.1    GBRD01000413    JAG65408.1    GDHC01010364    JAQ08265.1    KM008611    AIN46597.1    GFAC01003337    JAT95851.1    GBHO01037631    JAG05973.1    SAUD01029459    RXG54888.1    GEFM01002377    JAP73419.1    GEGO01000255    JAR95149.1    SAUD01024053    RXG56573.1    ABJB010058208    ABJB010167361    ABJB010618350    ABJB010929525    DS778349    EEC09530.1    GEFH01002490    JAP66091.1    HACA01010567    CDW27928.1    HACA01010570    CDW27931.1    GEDV01008527    JAP80030.1    ACPB03003820    DQ318855    ABC33914.1    GBBM01000535    JAC34883.1    KK113013    KFM59090.1    AGBW02012723    OWR44549.1    GFPF01008338    MAA19484.1   

Proteomes

UP000005204    UP000283053    UP000007151    UP000053240    UP000053268    UP000037510    + More
UP000036403    UP000235965    UP000007755    UP000078541    UP000075809    UP000078542    UP000005205    UP000000311    UP000078540    UP000076502    UP000008237    UP000053825    UP000053097    UP000279307    UP000053105    UP000242457    UP000005203    UP000027135    UP000007266    UP000192223    UP000078492    UP000245037    UP000000305    UP000076858    UP000015103    UP000094527    UP000283509    UP000288706    UP000001555    UP000054359   

PRIDE

H9IXJ3    Q05187   

Pfam

PF00868   Transglut_N        + More
PF01841   Transglut_core
PF00927   Transglut_C
PF05485   THAP

Interpro

IPR014756   Ig_E-set        + More
IPR023608   Transglutaminase_animal       
IPR036985   Transglutaminase-like_sf       
IPR002931   Transglutaminase-like       
IPR038765   Papain-like_cys_pep_sf       
IPR013783   Ig-like_fold       
IPR001102   Transglutaminase_N       
IPR036238   Transglutaminase_C_sf       
IPR008958   Transglutaminase_C       
IPR013808   Transglutaminase_AS       
IPR006612   THAP_Znf       

SUPFAM

SSF81296   SSF81296        + More
SSF54001   SSF54001       
SSF49309   SSF49309       

Gene 3D

2.60.40.10     3.90.260.10    

ProteinModelPortal

H9IXJ3   A0A3S2LTZ0   A0A2W1BNN0   A0A212FNQ8   A0A194R102   A0A194QFA5   + More
A0A2H1W2Z2   A0A0L7KZY8   A0A0J7KRL0   A0A2J7PV97   F4WRW8   A0A195FLR1   A0A151XIU9   A0A195BZU0   A0A158NEJ8   E2AYU1   E9ID81   A0A195BUU7   A0A154P0F6   E2B2K7   A0A0L7RFM3   A0A026WXV5   A0A3L8DGG8   A0A0M9A5H6   A0A310SIN2   A0A2A3ERM9   A0A088AKR6   A0A067RI89   A0A0C9QRW2   A0A1Y1KRA9   D6WH00   A0A1B6EUM3   A0A1Y1KS20   A0A1B6D4M4   A0A1W4WI76   A0A1B6KC33   A0A195EN57   A0A2P8YH94   A0A0P5LX05   A0A0P4XT55   A0A0N8C9J7   A0A0P5V592   A0A0P5B761   E9FR81   A0A0P5VIZ2   A0A162DAJ7   A0A0P6DKR4   A0A0P5WA68   A0A0P5XBZ4   A0A0N8AAG4   A0A0P6C2U9   A0A1B6I894   A0A0P5VMP7   A0A1B6K5T3   A0A023EZ45   A0A0P5ML04   Q05187   A0A224XJ93   A0A0V0G4Q1   A0A023F0E9   A0A0V0G7A9   A0A1B6H930   A0A2P2HW15   T1HFS7   A0A224XI60   A0A1D2N8Q4   A0A023EZ44   A0A0V0G6K0   T1J480   A0A0P6IF44   A0A2P6L0I5   A0A023FM45   T1I8S6   A0A023F227   A0A3R7SJE1   A0A2J7QXL3   T1HFP9   A0A224XFQ6   A0A0K8TIJ3   A0A146LM26   A0A0M3LC01   A0A1E1X9T3   A0A0A9WHI8   A0A444SNA9   A0A131Y2F0   A0A147BWD1   A0A444ST60   B7PSF8   A0A131XKN6   A0A0K2TPI8   A0A0K2TRC0   A0A131YNM1   T1HFV3   A3DT47   A0A023GNS4   A0A087T1V1   A0A212ESV0   A0A224YZS7  

PDB

1EX0     E-value=6.82325e-15,     Score=194

KEGG

101741185    K05619 transglutaminase 1 [EC:2.3.2.13] | (RefSeq) hemocyte protein-glutamine gamma-glutamyltransfer

GO

GO:0003810   GO:0018149   GO:0046872   GO:0003677   GO:0008233   GO:0016020   GO:0016021   GO:0008270   GO:0005515   GO:0042555   GO:0006260   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

Subcellular location

Membrane  

Length:

274

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00038

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01332

outside

1  -  274

 

 

Pi

206.766838

Theta

183.390207

Tajima's D

0.763116

CLR

0.057071

CSRT

0.595020248987551

Interpretation

Uncertain