Gene

KWMTBOMO11315

Pre Gene Modal

BGIBMGA001985

Annotation

PREDICTED:_protein_fem-1_homolog_B_isoform_X4_[Bombyx_mori]

Location

Bomo_Chr19(-):3103062-3125360      View in EpiBrowser

Full name

Protein fem-1 homolog B      

Alternative Name

FEM1-beta

Location in the cell

Cytoplasmic   Reliability : 1.502

CDS

ATGGAGAGAGAAGATAATGATCGCCTAGTTTTATTCAACGAACTAGCAAACTCGTTGAGGGAACGTGTATTCTTCGCAGCCAGAGATGGGATGTCTCTGACTCTTTACGCTTTGCTGTATGAAAAGAAAACTGATGAAATTGATGACTTATTAAACAATGATGTATGCAGCGATGGAGTTAAATGCACACCCCTCATCACGGCAGCTAGACATGGGCGAGAGGGTGCAGTCAGAATTTTATTGGAGAAGTTCAGACCACCGGTCTGTTTAGAAACTGAAGGGACAGTTAAGTTTGATGAATATGTAATCGAGGGAGCGACGGCACTATGGTGTGCCTCCGGGGCTGGTCACTTGGCTATCGTGAAGCGTCTGGTCAAAGCCGGTGCGGACGTTAACCACGCGACCAGGACGGTCAGCACTCCACTCCGAGCGGCCTGCTTCGAAGGACGCCTGGACATAGTCAAGTATCTGGTCAGACACGGCGCCGACATTCACAAGGCGAACAAATACAACAACACTTGCCTGATGATCGCTGCCTACAAAGGTTATTTGGATGTGGTGCAGTTCTTATTGGACAGCGGTGCGCGCGTCGACGACCGCGCCTTGTGCGGCGCGACCGCTCTGCATTTCGCGGCCGAGTGTGGGCACGCCGCGGTCGTCTGTTCGCTTCTCGATCACGGCGCCAAAATGCTGACCAACGAGAACGGTATGACGCCGCTGCAGTGTGCCGCCGAGCGCGCGCGGGCTTCGGTGGTCGAGATCCTGGCGGCGAGGCCAGAAGTCACGCGGGCCGAAGCTATCGAAGCTTACGAGCTTTTGGGCGCTTCCTTCGCCAACGACAAGGAATATTACTGTTTGAGGATGGCTTACCAGTATTTGCACCGAGCTATGGCGATGCGGTACGACCCGCGCTACGGCGAGATGTTGAAGCGTCCCAGCACGCCGATACCGGCGTACGATAATTGGAAGGAAACTACGACTTTAGAGGAGGTGGAGCGTCTCCAGGGCGACGCGCACGGGCTGCACATGGAGGGGCTGACGGTGCGCGAGCGCGTGCTGGGCGCGGCGTGCCCGGACCTGCCGCACCCGATCGTGTTCCGCGGCGCCGTGTTCGCGGACGAGGCGCGCTTCGACCGCTGCCTCGCGCTGTGGAGGCACGCGCTGCACCTGCGCCAGCAGAACCAGCAGGTGTCAGTCGTAAAGGATTTGCTCAGATTTGCTCAAGTATTCTCGCAGATGATTCACATCGGCATCGAACTGCCACTTGCACAGGTGTGCTACGTATTGGAGGCATGCGCTGAGGAGCTCCGGCGGGGCATGAAGCGTCTCCTGAAGCCGAATCCTCAGCACGACCCGGACTCCTTAGTTGAGGAGTACGACAGCAACGTGAAGACCGCGCTGTACCTGGTCGCGGTGGCCGGCCGCCTGCTCGAGGACTCTGGGAACTGTGAGGGCACGCGCTCGGCGGCCCGGCGCGCCGTGTTCGCGATGCGCGGCGCCCGCGTGCGCTCGGGGCAGACGCTGCTGCACCTGGCGGCCGACCGGAACACGCCCGTCGACGACTTCCACACCAGCGACGTGTGCCAGTTTCCGTGCGCGCGCACGTCCCGCCTGCTGCTGGACTGCGGCGCGGACGTGGACGCGGCCGACATGAACCGGCGGACGCCGCTGCACGTCGCCCTCATCTCCTACCAGCTCACGTCAGATGACAGAGAACAGTACAACGAAGCGTTCTGCGGCGTCGTGTGCGAACTGTTGTCCCGAGGAGCCCACGTGGACGCCATGGACCTCGACGGCATCACGCCATTAGTCGCTTCCATAGGAGGTCCGGCTGAGAGTCTGGTGCGTTCGGCCCTAAGGCCTCGTCTGTCCTGCATATCGGCTTCGGTGCTCGCCCTACACCGGGTGCGCTACCGACCCTCGCAGGTGCCGCGGGACCTGCACGCCTTCCTCATCATGCACGGCGTCCTGCCCGTCAATTAA

Protein

MEREDNDRLVLFNELANSLRERVFFAARDGMSLTLYALLYEKKTDEIDDLLNNDVCSDGVKCTPLITAARHGREGAVRILLEKFRPPVCLETEGTVKFDEYVIEGATALWCASGAGHLAIVKRLVKAGADVNHATRTVSTPLRAACFEGRLDIVKYLVRHGADIHKANKYNNTCLMIAAYKGYLDVVQFLLDSGARVDDRALCGATALHFAAECGHAAVVCSLLDHGAKMLTNENGMTPLQCAAERARASVVEILAARPEVTRAEAIEAYELLGASFANDKEYYCLRMAYQYLHRAMAMRYDPRYGEMLKRPSTPIPAYDNWKETTTLEEVERLQGDAHGLHMEGLTVRERVLGAACPDLPHPIVFRGAVFADEARFDRCLALWRHALHLRQQNQQVSVVKDLLRFAQVFSQMIHIGIELPLAQVCYVLEACAEELRRGMKRLLKPNPQHDPDSLVEEYDSNVKTALYLVAVAGRLLEDSGNCEGTRSAARRAVFAMRGARVRSGQTLLHLAADRNTPVDDFHTSDVCQFPCARTSRLLLDCGADVDAADMNRRTPLHVALISYQLTSDDREQYNEAFCGVVCELLSRGAHVDAMDLDGITPLVASIGGPAESLVRSALRPRLSCISASVLALHRVRYRPSQVPRDLHAFLIMHGVLPVN

Description

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis (By similarity).

Subunit

Component of some E3 ubiquitin-protein ligase complex.

Similarity

Belongs to the fem-1 family.

Keywords

ANK repeat   Apoptosis   Complete proteome   Cytoplasm   Nucleus   Reference proteome   Repeat   TPR repeat   Ubl conjugation pathway  

Feature

chain  Protein fem-1 homolog B

Uniprot

H9IXK2   A0A2H1VEQ0   A0A2A4JA41   A0A2W1BNB1   A0A2A4J8M2   A0A194QEW4   + More
A0A2A4JA58   A0A212F0D1   A0A2J7QQF5   A0A2J7QQF1   A0A2J7QQE0   A0A2J7QQE6   A0A067RA81   H3K3W7   A0A1B6ET95   D6WRB1   A0A1Y1MCG6   A0A0C9R0A5   A0A0P5SW40   A0A0P5LNB5   A0A3L8DHX9   A0A1W4X570   A0A026VZI6   A0A1W4X567   A0A0P6HB99   A0A195BS75   A0A158P1S3   E2AGL7   A0A0P5XCA4   A0A0P5YP61   A0A151XAX6   N6TRT9   A0A0P4WCQ1   A0A0K0WSR7   A0A195CLL9   A0A151J955   A0A193DXP8   E2B9W3   A0A195EQD1   A0A0P5D9H8   A0A0P5T399   A0A1W4X6M6   A0A154PBK6   F4W6N7   A0A0P4XM33   A0A0P6EVB7   A0A1W4WVR4   A0A232FF99   A0A3R7M9Y0   A0A2A3E8C3   A0A0P5IXQ8   A0A0T6B251   A0A0M9A3Z0   A0A1B6MEZ4   A0A0N8BVF4   A0A3Q0IWC7   T1JE69   A0A023F026   A0A0P4XXV9   A0A0P4Z447   A0A0P5N8D6   A0A0P5PKP8   A0A2P6K425   A0A2R5LD64   A0A087TTD0   A0A293MZF7   A0A131Z2D0   L7MIB1   A0A224YMU3   A0A1E1XBS6   A0A1B6K150   A0A3S3PB96   A0A336M0K2   A0A075TYJ8   A0A343BS05   A0A336M913   A0A210R2R5   A0A2T7NEZ5   B7P1P1   A0A131XX86   A0A1S3JT44   A0A1Q3FCQ6   A0A2I4CXQ8   Q16TW5   A0A182G7U1   A0A3B5KFK4   A0A3Q3A9B1   A0A146XN32   A0A3B3Y2L7   A0A151M8U6   A0A3B3ZPS1   F7C5B0   M4A554   A0A3B5MXQ8   A0A087X354   A0A1W5A3P6   Q5ZM55   T1DN19   R4GJS8  

Pubmed

19121390    28756777    26354079    22118469    24845553    18362917    + More
19820115    28004739    30249741    24508170    21347285    20798317    23537049    26188322    21719571    28648823    25474469    26830274    25576852    28797301    28503490    28812685    17510324    26483478    21551351    22293439    25463417    17495919    23542700    15642098    23758969    25727380    15592404   

EMBL

BABH01018278    BABH01018279    BABH01018280    ODYU01002171    SOQ39323.1    NWSH01002431    + More
PCG68310.1    KZ150054    PZC74356.1    PCG68311.1    KQ459053    KPJ04078.1    PCG68312.1    AGBW02011140    OWR47154.1    NEVH01012087    PNF30810.1    PNF30806.1    PNF30808.1    PNF30809.1    KK852639    KDR19644.1    AB698671    BAL61212.1    GECZ01028587    JAS41182.1    KQ971354    EFA05982.1    GEZM01040003    JAV81017.1    GBYB01001410    JAG71177.1    GDIQ01221297    GDIP01134488    LRGB01000996    JAK30428.1    JAL69226.1    KZS14242.1    GDIQ01167406    JAK84319.1    QOIP01000008    RLU19802.1    KK107536    EZA49198.1    GDIQ01021666    JAN73071.1    KQ976419    KYM89364.1    ADTU01006777    ADTU01006778    GL439322    EFN67437.1    GDIP01075786    JAM27929.1    GDIP01055099    JAM48616.1    KQ982335    KYQ57450.1    APGK01054055    KB741247    KB632281    ENN71980.1    ERL91316.1    GDRN01051405    JAI66397.1    KR108011    AKS25865.1    KQ977595    KYN01621.1    KQ979492    KYN21221.1    KT258023    ANN47504.1    GL446605    EFN87550.1    KQ982021    KYN30490.1    GDIP01160981    JAJ62421.1    GDIP01133182    JAL70532.1    KQ434869    KZC09299.1    GL887707    EGI70113.1    GDIP01239285    JAI84116.1    GDIQ01064803    JAN29934.1    NNAY01000337    OXU29109.1    QCYY01001581    ROT76986.1    KZ288353    PBC27301.1    GDIQ01208904    JAK42821.1    LJIG01016231    KRT81221.1    KQ435762    KOX75473.1    GEBQ01005493    JAT34484.1    GDIQ01141027    JAL10699.1    JH432116    GBBI01003869    JAC14843.1    GDIP01237431    JAI85970.1    GDIP01219678    JAJ03724.1    GDIQ01148431    JAL03295.1    GDIQ01148432    JAL03294.1    MWRG01031270    PRD21083.1    GGLE01003327    MBY07453.1    KK116644    KFM68369.1    GFWV01019807    MAA44535.1    GEDV01003110    JAP85447.1    GACK01002110    JAA62924.1    GFPF01007791    MAA18937.1    GFAC01002530    JAT96658.1    GECU01002545    JAT05162.1    NCKU01003030    NCKU01002680    NCKU01001891    RWS08324.1    RWS09027.1    RWS10986.1    UFQT01000259    SSX22539.1    KJ755434    AIG62901.1    KY465662    AQX36194.1    SSX22538.1    NEDP02000703    OWF55318.1    PZQS01000013    PVD19715.1    ABJB010387677    DS617630    EEC00513.1    GEFM01003922    JAP71874.1    GFDL01009767    JAV25278.1    CH477638    EAT37961.1    JXUM01000587    KQ560108    KXJ84486.1    GCES01151765    GCES01043249    JAR43074.1    AKHW03006295    KYO20933.1    AYCK01025766    AYCK01025767    AJ719529    GAAZ01000907    GBKC01001336    JAA97036.1    JAG44734.1    AADN05000047   

Proteomes

UP000005204    UP000218220    UP000053268    UP000007151    UP000235965    UP000027135    + More
UP000007266    UP000076858    UP000279307    UP000192223    UP000053097    UP000078540    UP000005205    UP000000311    UP000075809    UP000019118    UP000030742    UP000078542    UP000078492    UP000008237    UP000078541    UP000076502    UP000007755    UP000215335    UP000283509    UP000242457    UP000053105    UP000079169    UP000054359    UP000285301    UP000242188    UP000245119    UP000001555    UP000085678    UP000192220    UP000008820    UP000069940    UP000249989    UP000005226    UP000264800    UP000265000    UP000261480    UP000050525    UP000261520    UP000002280    UP000002852    UP000261380    UP000028760    UP000192224    UP000000539   

PRIDE

H9IXK2   

Pfam

PF12796   Ank_2        + More
PF00023   Ank
PF13606   Ank_3

Interpro

IPR002110   Ankyrin_rpt        + More
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR011990   TPR-like_helical_dom_sf       
IPR018120   Glyco_hydro_1_AS       

SUPFAM

SSF48403   SSF48403       

Gene 3D

1.25.40.20     1.25.40.10    

CDD

cd00204  ANK

ProteinModelPortal

H9IXK2   A0A2H1VEQ0   A0A2A4JA41   A0A2W1BNB1   A0A2A4J8M2   A0A194QEW4   + More
A0A2A4JA58   A0A212F0D1   A0A2J7QQF5   A0A2J7QQF1   A0A2J7QQE0   A0A2J7QQE6   A0A067RA81   H3K3W7   A0A1B6ET95   D6WRB1   A0A1Y1MCG6   A0A0C9R0A5   A0A0P5SW40   A0A0P5LNB5   A0A3L8DHX9   A0A1W4X570   A0A026VZI6   A0A1W4X567   A0A0P6HB99   A0A195BS75   A0A158P1S3   E2AGL7   A0A0P5XCA4   A0A0P5YP61   A0A151XAX6   N6TRT9   A0A0P4WCQ1   A0A0K0WSR7   A0A195CLL9   A0A151J955   A0A193DXP8   E2B9W3   A0A195EQD1   A0A0P5D9H8   A0A0P5T399   A0A1W4X6M6   A0A154PBK6   F4W6N7   A0A0P4XM33   A0A0P6EVB7   A0A1W4WVR4   A0A232FF99   A0A3R7M9Y0   A0A2A3E8C3   A0A0P5IXQ8   A0A0T6B251   A0A0M9A3Z0   A0A1B6MEZ4   A0A0N8BVF4   A0A3Q0IWC7   T1JE69   A0A023F026   A0A0P4XXV9   A0A0P4Z447   A0A0P5N8D6   A0A0P5PKP8   A0A2P6K425   A0A2R5LD64   A0A087TTD0   A0A293MZF7   A0A131Z2D0   L7MIB1   A0A224YMU3   A0A1E1XBS6   A0A1B6K150   A0A3S3PB96   A0A336M0K2   A0A075TYJ8   A0A343BS05   A0A336M913   A0A210R2R5   A0A2T7NEZ5   B7P1P1   A0A131XX86   A0A1S3JT44   A0A1Q3FCQ6   A0A2I4CXQ8   Q16TW5   A0A182G7U1   A0A3B5KFK4   A0A3Q3A9B1   A0A146XN32   A0A3B3Y2L7   A0A151M8U6   A0A3B3ZPS1   F7C5B0   M4A554   A0A3B5MXQ8   A0A087X354   A0A1W5A3P6   Q5ZM55   T1DN19   R4GJS8  

PDB

6NE2     E-value=1.26098e-23,     Score=274

KEGG

101738320    K10349 Fem-1 homolog b | (RefSeq) protein fem-1 homolog B

GO

GO:2000001   GO:0005123   GO:0060442   GO:0051438   GO:1902041   GO:0004842   GO:0060743   GO:0005654   GO:0005829   GO:0005634   GO:0005737   GO:0016567   GO:0006915   GO:0005515   GO:0003676   GO:0008270   GO:0042555   GO:0006260   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

Subcellular location

Cytoplasm   Associated with chromatin.   With evidence from 1 publications.
Nucleus   Associated with chromatin.   With evidence from 1 publications.

Length:

660

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0920699999999999

Exp number, first 60 AAs:

0.01281

Total prob of N-in:

0.00425

outside

1  -  660

 

 

Pi

272.138564

Theta

180.699205

Tajima's D

1.027243

CLR

0.135015

CSRT

0.666816659167042

Interpretation

Uncertain