Gene

KWMTBOMO11306

Pre Gene Modal

BGIBMGA001988

Annotation

PREDICTED:_transient_receptor_potential_cation_channel_trpm_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr19(-):2755388-2790374      View in EpiBrowser

Full name

Transient receptor potential cation channel trpm      

Alternative Name

Transient receptor potential cation channel, subfamily M ortholog

Location in the cell

PlasmaMembrane   Reliability : 4.333

CDS

ATGCTCGCGGAGAATCAGGAGAGAGAAGAGAGAACTTGCGACACGCATTCGTCGACGCCCGTCGTGTGTCTGGTCATCGAAGGTGGAACGAACACAGTGAGAGCGGTTCTGGAGTACGTGACTGATAACCCACCGGTGCCGGTGGTGGTCTGCGATGGAAGCGGTCGGGCAGCGGACCTCATCGCTTTTGTTCATAAGTACGCATCGGAAACCGGCGAACAAACAGTGCTGGAGTCAATGCGAGATTACCTGATAGGCACCATACAGAAGACCTTCGAAGTCGGACTGCAGCAAGCTGAGTGTTTGTACACGGAACTATTGCAGTGCACGAGAAAGAAGAATTTGATAACGGTCTTCAGGATTCAAGAGCGTGCAGAAGGTGGAGAAGTCCAAGAGCTTGATCAGGTCATACTGACGGCGTTGTTCCGGGCCCAGCATCTGACTCCAAGTGAACAGTTGTCTTTAGCCCTCACTTGGAACCGGGTCGACATCGCCAGATCCGAGATCTTCGTTTACGGACAGGAATGGCCTCCAGGCGCCCTAGACGAAGCCATGATGCAAGCCCTGGAGCACGATAGGATCGACTTCGTTAAGCTTCTCCTCGAGAACGGCGTGTCCATGAGGAAATTCCTCACGATTCCTAGACTTGAAGAACTTTACAACACGAAGAGCGGGCCTAGTAACACCTTGAGGTACATCTTAAGGGACGTGAGGCCTCATCTGCCCAAAGGCTACGTGTACACGCTTCACGACATCGGTTTGGTGATCAACAAACTCATTGGCGGAGCTTATAGGTGCTACTACACACGTCGGAAGTTTCGACCGATCTACGCAAAGGTGATGAACAAAAGCGTCAATGTACATCGCAACAGTGCGTCCTTCACCAGGCATAACGCTGGAGGCCTGTCGCTCATCACCGGGTTCATGCCGGTCACCAGTGAAATGGCGCTTTTCGATTATCCTTTCAACGAGCTTTTAATGTGGGCAGTCCTAACGAAGAGACATCAAATGGCGCTCCTCATGTGGACACATGGCGAGGAGTCGCTTGCGAAATCGCTCATAGCATGCAAGCTGTACAAGGCCATGGCCCACGAGGCAGCCGAGGATGATATGGAGACTGAAGTTTATGAAGAGCTAAGGCACTACGGCAAAGAATTTGAGAATAAGGCTTTGGAGCTTCTAGATTACTGCTACCGCCAAGATGATGATCAGGCCCAGCAACTCCTCACGTGCGAGCTCCAGAACTGGTCCGGTCAGACCTGTCTCAGCTTAGCCGTGACCGCGAACCATCGTGCGCTACTCGCTCATCCGTGCTCACAAATAATCTTAGCGGACTTATGGATGGGCGGCCTCAGAACGAGAAAGAACACCAATCTCAAGGTAATTCTGAGCCTGCTGTGTCCGCTGTACATTCTGAGATTGGAGTTCAAGTCCAAAGAGGAACTTCAGCTGATGCCGCAGACGGAAGAAGAGCATCTAGAGAACGAGAGCATCGAGGATGATAGGAGCACCAAGGATCCGACAGATGCCGAGCAGGCGTTGATTGGCTCAGGGGAATGCGAGACCCGGGTCGATCAGAACGGGAAAGTTGGTAAAGTAGGATGGGAACCATCGTACAGAGAGCTGCCAGAGTACCACCCATCTGAAATTAAACGAATGAGGCCACTGCGACTGAGGAAGAAGATCTATGAGTTCTTTACGGCACCGATCACTAAATTTTGGGCCGATTCGATAGCCTACATATTGTTCCTGTTGATGTTTACATACACAGTATTAGTCAAGATGAATCCTACACCTTCTTGGCCGGAAATATATTCTATATGTTATATATTAACTTTCTTATGCGAGAAGATTAGAGAAATCGTAACATCCGAGCCTGTTGCCATTAGACATAAGTTCAGTGTGTGGGCATGGAACATGTGGAACACGTATGACGCTGGTTTTATAATATTCTTCTTAGTTGGATTGACGCTGAGACTCAGAGAGATCTCAAGAGACGTAGGGAGAGTTATATACTGCGTCGATATTATATATTGGTACCTAAGGATCTTGAATATATTGGGTGTCAATAAGTACTTAGGTCCCCTAGTCACAATGATGGGTAAAATGGTAAAGAACATGATATACTTCGTGGTGCTATTGCTAGTGGTATTAATGTCTTTCGGTGTTGCCAGACAAGCTATACTCCATCCAGATAAGGACGCTAGTTGGCATCTAATCAGAGAGGTTTTCTTCCAACCGTACTTCATGCTCTATGGGGAAGTATTCGCCGAGCAGATGGCGCCTCCTTGTGGCCTTCCGGGCCTTGAGGAGTGCCGGGTCGGCCACTGGGTCCCCCCGCTCGTCATGAGCGTATATCTGCTCATCGCTAACATATTACTCGTCAATCTTCTAATAGCCGTCTTCAATAACATCTTTATAGAAGTCAACGGAGTTTCCCATCAGGTTTCGATCGCGTTCATTACGTAG

Protein

MLAENQEREERTCDTHSSTPVVCLVIEGGTNTVRAVLEYVTDNPPVPVVVCDGSGRAADLIAFVHKYASETGEQTVLESMRDYLIGTIQKTFEVGLQQAECLYTELLQCTRKKNLITVFRIQERAEGGEVQELDQVILTALFRAQHLTPSEQLSLALTWNRVDIARSEIFVYGQEWPPGALDEAMMQALEHDRIDFVKLLLENGVSMRKFLTIPRLEELYNTKSGPSNTLRYILRDVRPHLPKGYVYTLHDIGLVINKLIGGAYRCYYTRRKFRPIYAKVMNKSVNVHRNSASFTRHNAGGLSLITGFMPVTSEMALFDYPFNELLMWAVLTKRHQMALLMWTHGEESLAKSLIACKLYKAMAHEAAEDDMETEVYEELRHYGKEFENKALELLDYCYRQDDDQAQQLLTCELQNWSGQTCLSLAVTANHRALLAHPCSQIILADLWMGGLRTRKNTNLKVILSLLCPLYILRLEFKSKEELQLMPQTEEEHLENESIEDDRSTKDPTDAEQALIGSGECETRVDQNGKVGKVGWEPSYRELPEYHPSEIKRMRPLRLRKKIYEFFTAPITKFWADSIAYILFLLMFTYTVLVKMNPTPSWPEIYSICYILTFLCEKIREIVTSEPVAIRHKFSVWAWNMWNTYDAGFIIFFLVGLTLRLREISRDVGRVIYCVDIIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLLVVLMSFGVARQAILHPDKDASWHLIREVFFQPYFMLYGEVFAEQMAPPCGLPGLEECRVGHWVPPLVMSVYLLIANILLVNLLIAVFNNIFIEVNGVSHQVSIAFIT

Description

Calcium channel mediating constitutive calcium ion entry.

Similarity

Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily.

Keywords

Alternative splicing   Complete proteome   Ion channel   Ion transport   Membrane   Phosphoprotein   Reference proteome   RNA editing   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Transient receptor potential cation channel trpm
splice variant  In isoform B, isoform C and isoform D.

Uniprot

A0A194R122   A0A3S2P3F4   H9IXK5   A0A084WMT1   A0A182HAI6   A0A182RUF8   + More
A0A1S4G7E1   A0A1L8DKF9   A0A182N9J3   A0A182WB94   A0A182X2A3   A0A1I8M2P8   W4VRK0   A0A384T281   A0A1I8JT75   Q7PT99   Q16JC7   A0A0A1WNF2   A0A182FFL8   A0A067R873   A0A2M4A299   A0A2M4A2H3   A0A2M4A2E1   A0A2M4B8G9   A0A0K8WAM8   W8AZI2   A0A2M4CSI3   W8AKE0   A0A1I8M2P6   A0A182PIT3   A0A0A1XCB9   A0A1B6DW32   A0A0K8UMW6   A0A1B6CHW9   A0A1I8M2Q3   A0A2M4CKX6   A0A1I8M2Q0   A0A0K8W6A0   A0A1I8M2P5   A0A0R3NKP2   A0A1Y1MEE7   A0A0P8Y3Q1   A0A1I8M2Q1   A0A034V3S7   A0A0P9BXU3   A0A0R3NKT9   A0A0R3NKI6   A0A0Q9XGL4   A0A0Q9XJP9   A0A2M3Z0A8   A0A1I8M2P9   A0A1I8M2P7   A0A0P9AEA7   A0A0Q9VY26   A0A0Q9W722   A0A3B0J3H7   A0A0R1DR22   A0A2M4CKI8   A0A0Q9XIH8   A0A0J9RD37   A0A034V838   A0A0R1DT00   A0A0Q5VMK0   A0A0Q5VLM6   A0A0Q9W9P5   A0A1I8M2Q2   A0A1B6E5Z4   B4MFT5   A0A0R1DWM3   A0A0Q5VMF2   A0A0Q9W5Y3   A0A2M4B8H7   A0A0J9RD88   A0A0Q9W945   A0A0Q9X7N1   B3NQF3   A0A1W4WC30   A0A0J9RDE2   B4P890   A0A1W4W0D3   A0A1W4WCH8   A0A0J9REF0   A0A2M4CSJ8   A0A1W4W0E0   A0A0Q9VY01   A0A0Q9X9I3   A0A1W4WB55   A0A0Q9VYT9   A0A0Q9VY23   B4MJT0   A0A1I8P4R3   A0A0Q9VY84   A0A0Q9X0W9   A8DYE2   A0A0Q9WAC5   A0A0Q5VNM3   A0A1W4WCF7   B7YZH3   A0A0Q5W046   A0A0R1DUZ6  

Pubmed

26354079    19121390    24438588    26483478    17510324    25315136    + More
12364791    25830018    24845553    24495485    15632085    17994087    28004739    18057021    25348373    17550304    22936249    10731132    12537572    12537569    17018572    18327897    12537568    12537573    12537574    16110336    17569856    17569867   

EMBL

KQ461073    KPJ09541.1    RSAL01000034    RVE51394.1    BABH01018315    BABH01018316    + More
BABH01018317    BABH01018318    ATLV01024507    ATLV01024508    ATLV01024509    KE525352    KFB51525.1    JXUM01005304    JXUM01005305    JXUM01005306    JXUM01005307    JXUM01005308    JXUM01005309    JXUM01005310    KQ560190    KXJ83914.1    GFDF01007254    JAV06830.1    GANO01002328    JAB57543.1    KX249699    AOR81476.1    APCN01003636    AAAB01008807    EAA04234.4    CH478017    EAT34369.1    GBXI01013708    JAD00584.1    KK852639    KDR19648.1    GGFK01001554    MBW34875.1    GGFK01001517    MBW34838.1    GGFK01001569    MBW34890.1    GGFJ01000151    MBW49292.1    GDHF01004167    JAI48147.1    GAMC01020269    JAB86286.1    GGFL01004112    MBW68290.1    GAMC01020268    JAB86287.1    GBXI01005697    JAD08595.1    GEDC01007412    JAS29886.1    GDHF01024393    JAI27921.1    GEDC01024308    JAS12990.1    GGFL01001390    MBW65568.1    GDHF01005914    JAI46400.1    CM000071    KRT01474.1    GEZM01035131    GEZM01035128    JAV83388.1    CH902619    KPU76305.1    KPU76306.1    KPU76308.1    GAKP01021006    JAC37946.1    KPU76304.1    KRT01476.1    KRT01464.1    CH933808    KRG04098.1    KRG04088.1    GGFM01001209    MBW21960.1    KPU76309.1    CH940667    KRF77706.1    KRF77697.1    OUUW01000001    SPP75907.1    CM000158    KRJ99640.1    GGFL01001601    MBW65779.1    KRG04087.1    CM002911    KMY93948.1    GAKP01021007    JAC37945.1    KRJ99645.1    CH954179    KQS62561.1    KQS62557.1    KRF77695.1    GEDC01003984    JAS33314.1    EDW57256.2    KRJ99648.1    KQS62563.1    KRF77703.1    GGFJ01000195    MBW49336.1    KMY93937.1    KRF77700.1    KRG04093.1    EDV55929.2    KMY93951.1    EDW91130.2    KMY93939.1    GGFL01004119    MBW68297.1    KRF77705.1    KRG04089.1    KRF77702.1    KRF77696.1    KRF77698.1    KRF77699.1    CH963846    EDW72369.2    KRF77704.1    KRF97549.1    AE013599    AY069181    KRF77694.1    KQS62556.1    ACL83127.1    KQS62562.1    KRJ99650.1   

Proteomes

UP000053240    UP000283053    UP000005204    UP000030765    UP000069940    UP000249989    + More
UP000075900    UP000075884    UP000075920    UP000076407    UP000095301    UP000075840    UP000007062    UP000008820    UP000069272    UP000027135    UP000075885    UP000001819    UP000007801    UP000009192    UP000008792    UP000268350    UP000002282    UP000008711    UP000192221    UP000007798    UP000095300    UP000000803   

PRIDE

H9IXK5    A8DYE2    B7YZH3   

Pfam

PF00520   Ion_trans        + More
PF16519   TRPM_tetra
PF18139   LSDAT_euk

Interpro

IPR041491   TRPM_SLOG        + More
IPR032415   TRPM_tetra       
IPR005821   Ion_trans_dom       
IPR037162   TRPM_tetra_sf       

Gene 3D

1.20.5.1010    

ProteinModelPortal

A0A194R122   A0A3S2P3F4   H9IXK5   A0A084WMT1   A0A182HAI6   A0A182RUF8   + More
A0A1S4G7E1   A0A1L8DKF9   A0A182N9J3   A0A182WB94   A0A182X2A3   A0A1I8M2P8   W4VRK0   A0A384T281   A0A1I8JT75   Q7PT99   Q16JC7   A0A0A1WNF2   A0A182FFL8   A0A067R873   A0A2M4A299   A0A2M4A2H3   A0A2M4A2E1   A0A2M4B8G9   A0A0K8WAM8   W8AZI2   A0A2M4CSI3   W8AKE0   A0A1I8M2P6   A0A182PIT3   A0A0A1XCB9   A0A1B6DW32   A0A0K8UMW6   A0A1B6CHW9   A0A1I8M2Q3   A0A2M4CKX6   A0A1I8M2Q0   A0A0K8W6A0   A0A1I8M2P5   A0A0R3NKP2   A0A1Y1MEE7   A0A0P8Y3Q1   A0A1I8M2Q1   A0A034V3S7   A0A0P9BXU3   A0A0R3NKT9   A0A0R3NKI6   A0A0Q9XGL4   A0A0Q9XJP9   A0A2M3Z0A8   A0A1I8M2P9   A0A1I8M2P7   A0A0P9AEA7   A0A0Q9VY26   A0A0Q9W722   A0A3B0J3H7   A0A0R1DR22   A0A2M4CKI8   A0A0Q9XIH8   A0A0J9RD37   A0A034V838   A0A0R1DT00   A0A0Q5VMK0   A0A0Q5VLM6   A0A0Q9W9P5   A0A1I8M2Q2   A0A1B6E5Z4   B4MFT5   A0A0R1DWM3   A0A0Q5VMF2   A0A0Q9W5Y3   A0A2M4B8H7   A0A0J9RD88   A0A0Q9W945   A0A0Q9X7N1   B3NQF3   A0A1W4WC30   A0A0J9RDE2   B4P890   A0A1W4W0D3   A0A1W4WCH8   A0A0J9REF0   A0A2M4CSJ8   A0A1W4W0E0   A0A0Q9VY01   A0A0Q9X9I3   A0A1W4WB55   A0A0Q9VYT9   A0A0Q9VY23   B4MJT0   A0A1I8P4R3   A0A0Q9VY84   A0A0Q9X0W9   A8DYE2   A0A0Q9WAC5   A0A0Q5VNM3   A0A1W4WCF7   B7YZH3   A0A0Q5W046   A0A0R1DUZ6  

PDB

5ZX5     E-value=3.02287e-177,     Score=1600

KEGG

101738592    K04978 transient receptor potential cation channel subfamily M member 3 | (RefSeq) transient recepto

GO

GO:0051262   GO:0005216   GO:0016021   GO:0016020   GO:0005385   GO:0034703   GO:0097682   GO:0010960   GO:0055069   GO:0072509   GO:0098655   GO:0070838   GO:0006811   GO:0005515   GO:0042555   GO:0006260   GO:0005622   GO:0006810   GO:0003824   GO:0055085  

Subcellular location

Membrane  

Length:

822

Number of predicted TMHs:

5

Exp number of AAs in TMHs:

110.75458

Exp number, first 60 AAs:

0.00463

Total prob of N-in:

0.03070

outside

1  -  564

TMhelix

565  -  587

inside

588  -  634

TMhelix

635  -  657

outside

658  -  666

TMhelix

667  -  686

inside

687  -  706

TMhelix

707  -  729

outside

730  -  784

TMhelix

785  -  807

inside

808  -  822

 

 

Pi

236.641274

Theta

164.451781

Tajima's D

0.901583

CLR

0.076091

CSRT

0.632818359082046

Interpretation

Uncertain