Gene

KWMTBOMO11250

Pre Gene Modal

BGIBMGA012623

Annotation

PREDICTED:_general_transcription_factor_IIH_subunit_4-like_[Plutella_xylostella]

Location

Bomo_Chr19(+):1998680-2009558      View in EpiBrowser

Full name

General transcription factor IIH subunit 4      

Location in the cell

Mitochondrial   Reliability : 1.6 PlasmaMembrane   Reliability : 1.252

CDS

ATGTCAGAGTCTTCTAAATCGAAGTCTTTAAATTTGAATCCTTCGCCTACACTACAATGCAAAGACCTTCACGAATATCTTAAGTCGCGGTCTCCGCAGTTTCTAGAGACTCTTTACAATTACCCCACTATATGTCTCGCTGTATATCGCGAATTACCAGAGCTAGCACGTCACTTCGTAATCCGCTTGCTGTTCGTTGAGCAGCCAGTCCCACAGGCAGTTGTCACATCCTGGGTCTCGCAAACATATGCCAAAGAACAAGCAAAAGCATGCACTACACTGTCAGAGCTCTCCGTGTGGCAGGAGGCCCCCATACCGGGGGGCATGCCGGGCTGGATGCTCGCACAGTCGTTTAAAAAGAACCTCAAAGTGTCATTGCTTGGGGGAGGCAGGGCGTGGAGCATGTCGTCGTCGCTGGAGCCGGACGGGAAGGCCCGGGACGTGTCGTTCCTGGACGCGTACGCGCTGGAGCGCTGGGAGTGCGTGCTGCACTACATGGTGGGCAGCGCGCAGACCGAGGGCATCAGCGCCGACGCCGTCCGCATACTGCTGCACGCCGGACTCATGACCAGAGACGCAGAAGACGGGTCCGCCGTTATCACTCGCGCCGGCTTCCAGTTTCTGCTCCTGAGTACACCCAAGCAGGTGTGGCTGTTCCTGCAGCACTACCTGCACACGGCCGAGCGCCGCAGCCTCAGCGCCGCCGAGTGCCTGGCCTTCCTCTACCAGCTCAGCTTCAGCACCCTGGGGAAGGACTACAGCACGGAGGGCATGAGCAACAACATGCTGGTGTTCCTGCAGCACCTGCGGGAGTTCGGCCTCGTCTACCAGAGGAAGCGCAAGGCGGGCCGCTTCTACCCCACCCGCCTCGCGCTCAACATCCTGCGCGTGCGCTGCGCCGCGCCGCTCGAGGCCGCCGCCGGCGCGCGCGGACACCTCGTGCTGGAGACCAACTACCGCGTGTACGGCTACACCTCCTCCGACCTGCAGGTCGCGCTGCTCGGCCTCTTCACGGAGCTCATCTACAGGTTCCCCAACGTGGTGGTGGGCGTGGTGAGCCGGGAGTCCGTCCGCCAGGCGCTGCGCGGTGGCATCACGGCCGAGCAGATCATCCACTACCTGGAGCAGCACGCGCACCCGCAGATGCTGAAGTCAGAGACGGGCGGCATCCGGTCGGCGTCGATGCTGCCCCCCACCGTGGTGGACCAGATCCGCCTGTGGGAGTCCGAGAGGAACCGCTGCGTCTACACGGAGGGGGTCGTCTACAACCAGTTCCTGTCGCAGGCCGACTTCGTGGTGCTGCGGGACCACGCCCGCGCGGCCGGGGTGCTGAGCTGGCAGCACGAGCGCGCGCGGACCATGGTGGTGACCCGCGCCGGACACGACGACGTCAAGAAGTTCTGGAAGCGCTACTCCAAGAACAGCTAG

Protein

MSESSKSKSLNLNPSPTLQCKDLHEYLKSRSPQFLETLYNYPTICLAVYRELPELARHFVIRLLFVEQPVPQAVVTSWVSQTYAKEQAKACTTLSELSVWQEAPIPGGMPGWMLAQSFKKNLKVSLLGGGRAWSMSSSLEPDGKARDVSFLDAYALERWECVLHYMVGSAQTEGISADAVRILLHAGLMTRDAEDGSAVITRAGFQFLLLSTPKQVWLFLQHYLHTAERRSLSAAECLAFLYQLSFSTLGKDYSTEGMSNNMLVFLQHLREFGLVYQRKRKAGRFYPTRLALNILRVRCAAPLEAAAGARGHLVLETNYRVYGYTSSDLQVALLGLFTELIYRFPNVVVGVVSRESVRQALRGGITAEQIIHYLEQHAHPQMLKSETGGIRSASMLPPTVVDQIRLWESERNRCVYTEGVVYNQFLSQADFVVLRDHARAAGVLSWQHERARTMVVTRAGHDDVKKFWKRYSKNS

Description

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.

Similarity

Belongs to the TFB2 family.

Uniprot

H9JSW1   A0A2W1BMC3   A0A212F2G2   A0A2A4JXQ6   A0A2H1VRK8   A0A1W4XA12   + More
A0A1Y1LPE6   A0A0N1ICW4   A0A182RKF3   A0A182UFC4   D6WU09   A0A182WUK1   A0A182FTP8   A0A182VHI5   A0A182KKF9   Q7QH12   A0A182HVX2   A0A182NZX6   A0A182MCE1   A0A182N2Z6   W5JH20   A0A182IRW5   A0A182JV50   A0A182W221   A0A182YBM3   A0A2M4AHE0   A0A182Q025   A0A195ER83   A0A067R066   A0A182HD83   E2B8N7   Q176J9   A0A154PDQ4   A0A0M8ZZ27   E2AJG8   A0A1B0GJ18   A0A151WNZ1   A0A195DMQ2   A0A195AVR0   A0A151I7U4   A0A087ZX20   A0A158P1W3   A0A026WC09   A0A2A3EBW6   A0A1Q3F3U2   B0WFU1   A0A084W999   W8C5B7   K7JBE3   A0A1I8MA08   A0A1I8P8E8   A0A2P8ZEZ1   A0A0L0CDV9   A0A240SWY5   A0A1B0AR15   A0A1A9Z8Z4   A0A1A9YG33   A0A034VQF4   A0A1A9V4D4   A0A1B6MGU7   U4UR34   E0VYT4   N6TTI5   A0A336K8B7   A0A1B6H6W5   A0A1B6C308   A0A310SPQ2   B3MAD1   B4KUK0   B4LH90   A0A1W4VNC4   A0A3B0KWK2   B4N4V6   Q2M1D2   B4GUA2   B4IWU6   A0A0A9Y7B7   B3NI43   B4ITX7   A0A0J9RVN7   B4HIG7   Q9VUR1   A0A0P4VQN4   F4W639   A0A069DU73   A0A0V0G7D6   A0A224XC95   B4QL39   T1HG45   A0A182TUF5   A0A0L7R9A6   A0A023F391   A0A0M4EBB5   A0A2R7WBZ7   L7M5B7   A0A224ZAR2   A0A131YRK0   A0A1E1XG20   A0A131Y1W6   A0A2R5LGB0  

Pubmed

19121390    28756777    22118469    28004739    26354079    18362917    + More
19820115    20966253    12364791    14747013    17210077    20920257    23761445    25244985    24845553    26483478    20798317    17510324    21347285    24508170    30249741    24438588    24495485    20075255    25315136    29403074    26108605    25348373    23537049    20566863    17994087    15632085    25401762    26823975    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    27129103    21719571    26334808    25474469    25576852    28797301    26830274    28503490   

EMBL

BABH01035991    BABH01035992    BABH01035993    KZ149965    PZC76209.1    AGBW02010741    + More
OWR47930.1    NWSH01000411    PCG76589.1    ODYU01003846    SOQ43112.1    GEZM01050589    GEZM01050588    JAV75509.1    KQ459449    KPJ00890.1    KQ971352    EFA07302.1    AAAB01008823    EAA05440.1    APCN01001435    AXCM01000173    ADMH02001207    ETN63662.1    GGFK01006882    MBW40203.1    AXCN02001144    KQ982021    KYN30417.1    KK852804    KDR16235.1    JXUM01129107    KQ567403    KXJ69446.1    GL446361    EFN87943.1    CH477386    EAT42083.1    KQ434879    KZC09983.1    KQ435794    KOX74030.1    GL439992    EFN66420.1    AJWK01019210    KQ982892    KYQ49622.1    KQ980724    KYN14153.1    KQ976731    KYM76328.1    KQ978397    KYM94206.1    ADTU01006900    KK107293    QOIP01000005    EZA53181.1    RLU22624.1    KZ288309    PBC28676.1    GFDL01012856    JAV22189.1    DS231920    EDS26435.1    ATLV01021659    KE525321    KFB46793.1    GAMC01009121    JAB97434.1    AAZX01015659    PYGN01000077    PSN55058.1    JRES01000502    KNC30598.1    CCAG010006155    JXJN01002206    GAKP01014902    JAC44050.1    GEBQ01004845    JAT35132.1    KB632331    ERL92616.1    DS235847    EEB18540.1    APGK01019264    KB740098    ENN81378.1    UFQS01000174    UFQT01000174    SSX00731.1    SSX21111.1    GECU01037270    JAS70436.1    GEDC01029390    JAS07908.1    KQ761323    OAD57894.1    CH902618    EDV40182.1    CH933809    EDW18228.2    CH940647    EDW70603.1    OUUW01000027    SPP89741.1    CH964101    EDW79395.1    CH379069    EAL30642.3    CH479191    EDW26185.1    CH916366    EDV97347.1    GBHO01016621    GBRD01002397    GDHC01016762    JAG26983.1    JAG63424.1    JAQ01867.1    CH954178    EDV52129.1    CH891737    EDW99840.1    CM002912    KMY99778.1    CH480815    EDW41597.1    AE014296    AAF49614.1    GDKW01001805    JAI54790.1    GL887707    EGI70174.1    GBGD01001414    JAC87475.1    GECL01002239    JAP03885.1    GFTR01006391    JAW10035.1    CM000363    EDX10564.1    ACPB03001139    KQ414628    KOC67341.1    GBBI01002989    JAC15723.1    CP012525    ALC44716.1    KK854594    PTY17214.1    GACK01006745    JAA58289.1    GFPF01012636    MAA23782.1    GEDV01006674    JAP81883.1    GFAC01000996    JAT98192.1    GEFM01002919    JAP72877.1    GGLE01004437    MBY08563.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000192223    UP000053268    UP000075900    + More
UP000075902    UP000007266    UP000076407    UP000069272    UP000075903    UP000075882    UP000007062    UP000075840    UP000075885    UP000075883    UP000075884    UP000000673    UP000075880    UP000075881    UP000075920    UP000076408    UP000075886    UP000078541    UP000027135    UP000069940    UP000249989    UP000008237    UP000008820    UP000076502    UP000053105    UP000000311    UP000092461    UP000075809    UP000078492    UP000078540    UP000078542    UP000005203    UP000005205    UP000053097    UP000279307    UP000242457    UP000002320    UP000030765    UP000002358    UP000095301    UP000095300    UP000245037    UP000037069    UP000092444    UP000092460    UP000092445    UP000092443    UP000078200    UP000030742    UP000009046    UP000019118    UP000007801    UP000009192    UP000008792    UP000192221    UP000268350    UP000007798    UP000001819    UP000008744    UP000001070    UP000008711    UP000002282    UP000001292    UP000000803    UP000007755    UP000000304    UP000015103    UP000053825    UP000092553   

PRIDE

H9JSW1    Q9VUR1   

Pfam

PF18307   Tfb2_C        + More
PF03849   Tfb2

Interpro

IPR040662   Tfb2_C        + More
IPR004598   TFIIH_p52/Tfb2       

ProteinModelPortal

H9JSW1   A0A2W1BMC3   A0A212F2G2   A0A2A4JXQ6   A0A2H1VRK8   A0A1W4XA12   + More
A0A1Y1LPE6   A0A0N1ICW4   A0A182RKF3   A0A182UFC4   D6WU09   A0A182WUK1   A0A182FTP8   A0A182VHI5   A0A182KKF9   Q7QH12   A0A182HVX2   A0A182NZX6   A0A182MCE1   A0A182N2Z6   W5JH20   A0A182IRW5   A0A182JV50   A0A182W221   A0A182YBM3   A0A2M4AHE0   A0A182Q025   A0A195ER83   A0A067R066   A0A182HD83   E2B8N7   Q176J9   A0A154PDQ4   A0A0M8ZZ27   E2AJG8   A0A1B0GJ18   A0A151WNZ1   A0A195DMQ2   A0A195AVR0   A0A151I7U4   A0A087ZX20   A0A158P1W3   A0A026WC09   A0A2A3EBW6   A0A1Q3F3U2   B0WFU1   A0A084W999   W8C5B7   K7JBE3   A0A1I8MA08   A0A1I8P8E8   A0A2P8ZEZ1   A0A0L0CDV9   A0A240SWY5   A0A1B0AR15   A0A1A9Z8Z4   A0A1A9YG33   A0A034VQF4   A0A1A9V4D4   A0A1B6MGU7   U4UR34   E0VYT4   N6TTI5   A0A336K8B7   A0A1B6H6W5   A0A1B6C308   A0A310SPQ2   B3MAD1   B4KUK0   B4LH90   A0A1W4VNC4   A0A3B0KWK2   B4N4V6   Q2M1D2   B4GUA2   B4IWU6   A0A0A9Y7B7   B3NI43   B4ITX7   A0A0J9RVN7   B4HIG7   Q9VUR1   A0A0P4VQN4   F4W639   A0A069DU73   A0A0V0G7D6   A0A224XC95   B4QL39   T1HG45   A0A182TUF5   A0A0L7R9A6   A0A023F391   A0A0M4EBB5   A0A2R7WBZ7   L7M5B7   A0A224ZAR2   A0A131YRK0   A0A1E1XG20   A0A131Y1W6   A0A2R5LGB0  

PDB

6O9M     E-value=5.03979e-134,     Score=1225

KEGG

101745815    K03144 transcription initiation factor TFIIH subunit 4 | (RefSeq) general transcription factor IIH s

PATHWAY

03022    Basal transcription factors - Bombyx mori (domestic silkworm)
03420    Nucleotide excision repair - Bombyx mori (domestic silkworm)

GO

GO:0006289   GO:0000439   GO:0001671   GO:0070816   GO:0005675   GO:0003690   GO:0010224   GO:0006366   GO:0016787   GO:0006367   GO:0001111   GO:0016740   GO:0001113   GO:0005634   GO:0016021   GO:0003743   GO:0004003   GO:0006508   GO:0005515   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

PANTHER

PTHR13152  

Subcellular location

Nucleus  

Length:

475

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.13642

Exp number, first 60 AAs:

0.00321

Total prob of N-in:

0.00500

outside

1  -  475

 

 

Pi

173.363522

Theta

146.168144

Tajima's D

0.399532

CLR

0.076116

CSRT

0.489125543722814

Interpretation

Uncertain