Silkworm Genome Informatics Database

Gene

KWMTBOMO11236 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA012610

Annotation

PREDICTED:_enhancer_of_mRNA-decapping_protein_3?_partial_[Bombyx_mori]

Location

Bomo_Chr19(+):1543715-1548147 View in EpiBrowser

Full name

Enhancer of mRNA-decapping protein 3

Alternative Name

LSM16 protein homolog
YjeF domain-containing protein 1

Location in the cell

Extracellular Reliability : 1.254 Nuclear Reliability : 1.114

CDS

ATGTCTAATTGGATTGGATACGCGGTTTCGGTGAACTGTGGCGAACCTTTAGGCTGCTATCAAGGCACCATCCTTGAAGCAGATGGAAACACGTTAACACTAACTAAAGCGTTTCGAAACGGATTTCCATATCCTAAATTGCAAGTTACACTCAATGCTGCAGATATAAAAGATTTAAAAATTATTGAAGCTAAACCAGAACCATCAGAGCAGACTCACAGCACAGTAGCAGTGACTAAGAGTGGCAAAAAAGCTCAGAAAGCAACAGTTTGTGAGAATTTACAGGCCAACCCTGCGCAGACTAGTTCAGGAACTCCATCAACTAGTGTTGTTAACAATAAATCTGCTAATCGCAATACAGTACAAGGCCCAACTCGCAGCAAACCCATTGAGATACAGGCAAATAGGAATAATAAAAATAATAACCATGCCGGTAGCTACGGCAACTGCAGCTCTACGCCGAAAGGTCGCAACCTCGTTGGTCAAGAAAAAGCAAGACGTCGGAATGAAGCATGCTTTGGAGAATCAACAGATGCCATCGATGACGATTTTGATTTTGAAGGGAACCTTGCACTGTTTGACAAACGTGCCTTCTGGGAGCAGATGAGAAATTCCCACAAACCTGACCTTGTCAGGCAAGCAGATGATGCTGGGAAGTATAAGCACGATGAGAACGTATTGGGAACTGCTCCGGTAGCCAGACACGCAATGAGAGTGCCAGATAACCTACGGGGTCCGATTGACTATGTAACTGACGAGGGGGTGATCGTTCCGTCGGTCGTGCCGCGCGTCCGCAGGCAGCTGTGGGAGGGTATGGTGAGCTACGGGCTAGCGGAGTGCGCGTACACGCTGCTGGCCCGCTGCGCCGCCGACGTGGCGCTGCGGCTGGTGGGCGGCGGGCGGCGCCTGGAGCCCCGCAACGCGCACCAGCCGCCCTGCGTGCTGGCCGTGCCCGGGCCGCACCGCGCCGGCGCCGCCGCCCTGCGCGCCGCCCGCCTGCTGGCCGCGCACGGCGCCCGCCCCGCCTACGTGCTGCCCGCCGCCGCCGCGCCCGCGCTGCAGCCCGACGTGGACGCGCTGGCGCTGTGCGGCGTGGCGCCGGCCGACGGACTGGACGCGGCGCCCAGCCCTGACCTCGTGCTGCTGGCGCTCTACGACCCGCTGCTCGACGACCCCCAGGACAAGTATGAATCTGTCCTGCAGTGGGTGGGCAACTGCCGAGCCCCCATCATCAGCATCGAGCCCCCGGCGCGCGGCTGGCGGAACGTGTCGGGGCGGGCCGCCGTGCTGTCGCTGGCGCCCCCGGCCGTGTCCCCCTCGCTGGGCAGACTCTACCTGGCCCACGTCGGAGCCCCCACCAAGGTGTACACGGACCTGCGCCTGGCTTACCGCCCGCCCTTCGGAGCCTCCACGTCCCTCGCGCTGCACCCGAGCGACGACTGA

Protein

MSNWIGYAVSVNCGEPLGCYQGTILEADGNTLTLTKAFRNGFPYPKLQVTLNAADIKDLKIIEAKPEPSEQTHSTVAVTKSGKKAQKATVCENLQANPAQTSSGTPSTSVVNNKSANRNTVQGPTRSKPIEIQANRNNKNNNHAGSYGNCSSTPKGRNLVGQEKARRRNEACFGESTDAIDDDFDFEGNLALFDKRAFWEQMRNSHKPDLVRQADDAGKYKHDENVLGTAPVARHAMRVPDNLRGPIDYVTDEGVIVPSVVPRVRRQLWEGMVSYGLAECAYTLLARCAADVALRLVGGGRRLEPRNAHQPPCVLAVPGPHRAGAAALRAARLLAAHGARPAYVLPAAAAPALQPDVDALALCGVAPADGLDAAPSPDLVLLALYDPLLDDPQDKYESVLQWVGNCRAPIISIEPPARGWRNVSGRAAVLSLAPPAVSPSLGRLYLAHVGAPTKVYTDLRLAYRPPFGASTSLALHPSDD

Description

Binds single-stranded RNA. Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping (By similarity).

Catalytic Activity

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Similarity

Belongs to the EDC3 family.

Keywords

Complete proteome Cytoplasm Phosphoprotein Reference proteome RNA-binding

Feature

chain Enhancer of mRNA-decapping protein 3

Uniprot

H9JSU9 A0A0N1IEX2 A0A0K8TNF9 A0A1L8DHQ9 A0A1L8DHR1 Q16Z12 + More
A0A1S4FJF0 H3B2E4 A0A1B0C914 A0A0P6JSM5 U5EFA9 A0A2R2MJ81 F1QL27 A0A1S3KCZ9 A0A182SAN4 A0A091GMS2 Q502M5 G1MUK9 A0A1S3ESP3 A0A182W2U2

Pubmed

19121390 26354079 26369729 17510324 9215903 26999592 + More
23594743 18307296 20838655

EMBL

BABH01035946 KQ461184 KPJ07505.1 GDAI01002138 JAI15465.1 GFDF01008194 + More
JAV05890.1 GFDF01008086 JAV05998.1 CH477505 EAT39854.1 AFYH01054097 AFYH01054098 AFYH01054099 AFYH01054100 AFYH01054101 AJWK01001740 AJWK01001741 AJWK01001742 GDUN01000276 JAN95643.1 GANO01003939 JAB55932.1 BX323018 KL504874 KFO84474.1 BC095641

Proteomes

UP000005204 UP000053240 UP000008820 UP000008672 UP000092461 UP000085678 + More
UP000000437 UP000075901 UP000001645 UP000081671 UP000075920

PRIDE

H9JSU9 Q502M5

Pfam

PF12701   LSM14        + More
PF03853   YjeF_N
PF09532   FDF
PF00168   C2
PF00397   WW
PF00632   HECT

Interpro

IPR004443   YjeF_N_dom        + More
IPR036652   YjeF_N_dom_sf
IPR034107   Lsm16_N
IPR019050   FDF_dom
IPR025762   DFDF
IPR025609   Lsm14-like_N
IPR000569   HECT_dom
IPR035983   Hect_E3_ubiquitin_ligase
IPR035892   C2_domain_sf
IPR036020   WW_dom_sf
IPR000008   C2_dom
IPR001202   WW_dom

SUPFAM

SSF64153   SSF64153        + More
SSF51045   SSF51045
SSF56204   SSF56204

Gene 3D

3.40.50.10260 2.60.40.150

CDD

cd01737  LSm16_N
cd00078  HECTc
cd00201  WW

ProteinModelPortal

H9JSU9 A0A0N1IEX2 A0A0K8TNF9 A0A1L8DHQ9 A0A1L8DHR1 Q16Z12 + More
A0A1S4FJF0 H3B2E4 A0A1B0C914 A0A0P6JSM5 U5EFA9 A0A2R2MJ81 F1QL27 A0A1S3KCZ9 A0A182SAN4 A0A091GMS2 Q502M5 G1MUK9 A0A1S3ESP3 A0A182W2U2

PDB

3D3J E-value=1.67263e-14, Score=194

KEGG

101736134 K12615 enhancer of mRNA-decapping protein 3 | (RefSeq) enhancer of mRNA-decapping protein 3

PATHWAY

03018 RNA degradation - Bombyx mori (domestic silkworm)

GO

GO:0031087 GO:0003729 GO:0004842 GO:0033962 GO:1990174 GO:0000932 GO:0036464 GO:0042802

Subcellular location

Processing bodies (PB). With evidence from 1 publications.

Length:

480

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0416

Exp number, first 60 AAs:

0.01609

Total prob of N-in:

0.00397

outside

1 - 480

Pi

290.680376

Theta

196.274209

Tajima's D

1.346149

CLR

0.003079

CSRT

0.748012599370032

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics