Gene

KWMTBOMO11235

Pre Gene Modal

BGIBMGA012590

Annotation

PREDICTED:_endoplasmic_reticulum_metallopeptidase_1-like_[Bombyx_mori]

Location

Bomo_Chr19(-):1528986-1538924      View in EpiBrowser

Full name

Endoplasmic reticulum metallopeptidase 1      

Alternative Name

Felix-ina

Location in the cell

PlasmaMembrane   Reliability : 1.887

CDS

ATGCCCATGAAGATGATGAAAGAGAATATCCTCCCACAACCTCCACTGTCAACATGGTGGCTATTTGTGGCACTTGCTGCTACAGGCTTATCATTATACGGAGTATCATTAATAGATTATGCATTACCAGAACCACTGACTAGAGCAGCTCCAGTTGAGAAGTTCATTGCAGACATAGCTTATGAGCATCTTGTCAATTTGACTTCTATTGGCCCTAGGGTGGCCGGTAGCTATGAAAACGAGGTGTTGGCCATCAACATACTAGTGGGGGCTGTCAAACAGATAGCCCGAGAGGCATCTCCCCACAATAGAGTGGAGCTAGACCTTCAAGTAGCAAGCGGTGCCTTCTCACTCACATTCCTTGATGGAATGACCAACGTATACCACGGCGTTCAGAACGTGGTGGTCCGCGTGTCGGGGGCGGGGGGCAGGCCGCGCGGCCGCCGGAGAACCGCGATACTCCTCAACTGTCACTTCGACACGGTCCCCGATAGTCCAGGAGCCAGCGACGACGGAGCCGGGTGCGCGGTGCTGCTGGAGGTGATGCGCGCCCTGGCGGCCACCCCGCACCCGCTGCGCCACGACGTCATATTCCTGCTCAACGGCGCCGAGGAGAACATTCTGCAGGCCTCGCACGGCTTCATCACGCAGCACAAATGGGCCAAGTCGGTGCGCGCCTTCATCAACATTGAGGCGTGCGGCGCGGGCGGGCGCGAGGTGCTGTTCCAGGCGGGGCCCGACGACCCCTGGATCATGGAGGTGTACGCGGCCGCCGTCCCGCACCCCTTCGCGTCGTCGCTGGCGCAGGAGCTGTTCCAGAGCGGCCTCATCCCGGCGGACACCGACTTCAGGATATTCAGGGACTTCGGGAAGCTCTCAGGCGTGGACCTCGCGTGGAGCTCGAACGGCTACGTGTACCACACCGGCCTGGACACGGCCGACAACATCCCCAAGTCCGCGCTGCAGCGCACCGGCGACAACGTGCTGGCCCTCACGCGGGGAATGCTCTCCAGCGAGAATCTAGAGAAAGAGGTGGACAAGTCAGGGCAGCTGGTGTACTTCGACGTGCTGGGCGCGGTGGTGATCTCCGGGCGGGCTCCGCTGGCCGCGCTGGCGGTGCTCGCAACCATCGCGCTCCTGCTGCTCAAGATACACGTCAACGCCACTAGAGCCAAGAAGGCGCGTGAGTACTCCCGCTGCTGA

Protein

MPMKMMKENILPQPPLSTWWLFVALAATGLSLYGVSLIDYALPEPLTRAAPVEKFIADIAYEHLVNLTSIGPRVAGSYENEVLAINILVGAVKQIAREASPHNRVELDLQVASGAFSLTFLDGMTNVYHGVQNVVVRVSGAGGRPRGRRRTAILLNCHFDTVPDSPGASDDGAGCAVLLEVMRALAATPHPLRHDVIFLLNGAEENILQASHGFITQHKWAKSVRAFINIEACGAGGREVLFQAGPDDPWIMEVYAAAVPHPFASSLAQELFQSGLIPADTDFRIFRDFGKLSGVDLAWSSNGYVYHTGLDTADNIPKSALQRTGDNVLALTRGMLSSENLEKEVDKSGQLVYFDVLGAVVISGRAPLAALAVLATIALLLLKIHVNATRAKKAREYSRC

Description

Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures.

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M28 family.

Keywords

Acetylation   Alternative splicing   Complete proteome   Disulfide bond   Endoplasmic reticulum   Glycoprotein   Hydrolase   Membrane   Metal-binding   Metalloprotease   Protease   Reference proteome   Transmembrane   Transmembrane helix   Zinc   3D-structure  

Feature

chain  Endoplasmic reticulum metallopeptidase 1
splice variant  In isoform 2.

Uniprot

A0A2H1VFV2   A0A212F2C4   A0A0N0P9G5   A0A0C9PTF3   U4UG35   A0A0J7N8Q2   + More
A0A0C9RLF9   K7IVE8   A0A1Y1MFR8   E9J751   N6TCR2   V5I8A6   A0A026WBF2   D6WUE4   F4W998   A0A151IAH4   A0A151J3X6   A0A151X8Z6   A0A158P124   A0A1L8DTQ3   A0A2P8XUX7   E2B4B7   A0A195F463   A0A195B525   A0A1L8DTY6   A0A2S2PLK7   A0A2H8TZN1   E2AM75   A0A0L7RC84   A0A2J7RN14   A0A087ZYD9   A0A2S2QYZ9   A0A1W4WC11   J9JNK1   A0A1B6EJY6   A0A2A3E4U7   A0A0M8ZU08   A0A1B6HGX1   A0A1B6LTH2   A0A0K8T9R5   A0A0A9YXT3   A0A093S894   A0A091FRS0   A0A0K2UB59   A0A1V4J8U0   A0A218V9N9   A0A091LXC2   A0A093CX59   A0A093QTD4   A0A091QKA7   A0A091I5H3   A0A087QSD9   A0A091IPN9   A0A091Q2Z9   A0A091ULW7   H0Z3K7   A0A0A0AXF3   A0A091W890   A0A091RUS3   M7B0C0   A0A091QIJ3   A0A146L905   A0A0A9YZF9   A0A3L8SN96   A0A091TIN8   A0A2I0U5B6   A0A091MHJ1   U3K7N8   A0A091EJV4   A0A0Q3PUG0   A0A1A8QIW3   A0A2J7PI20   A0A2Y9DFB7   A0A093FYF8   A0A226PN18   A0A093JAQ1   A0A1A7XYP6   U3I8J8   U6DHE9   A0A2J7PI21   A0A091H3C2   A0A099ZBA7   G3I7L3   A0A067R1N3   Q3UVK0   A0A3Q3DLX3   A0A226N5G8   A0A3Q3FWJ9   Q6UPR8   F1M6W2   A0A061IAA3   H2UKM2   G3VQE6   T1IR32   A0A3P8T428   A0A1A8DUM0  

EC Number

3.4.-.-

Pubmed

22118469    26354079    23537049    20075255    28004739    21282665    + More
24508170    18362917    19820115    21719571    21347285    29403074    20798317    25401762    20360741    23624526    26823975    30282656    24621616    21804562    24845553    16141072    15489334    14621295    21183079    17267443    23679341    15057822    23929341    21551351    21709235   

EMBL

ODYU01002351    SOQ39733.1    AGBW02010753    OWR47898.1    KQ459449    KPJ00913.1    + More
GBYB01004648    JAG74415.1    KB632339    ERL92929.1    LBMM01008247    KMQ89025.1    GBYB01007756    JAG77523.1    AAZX01004302    GEZM01036389    JAV82736.1    GL768421    EFZ11366.1    APGK01034851    KB740923    ENN78074.1    GALX01005020    JAB63446.1    KK107293    EZA53278.1    KQ971352    EFA07296.2    GL888002    EGI69280.1    KQ978223    KYM96266.1    KQ980275    KYN17027.1    KQ982402    KYQ56841.1    ADTU01001042    GFDF01004245    JAV09839.1    PYGN01001307    PSN35805.1    GL445549    EFN89465.1    KQ981855    KYN34874.1    KQ976598    KYM79596.1    GFDF01004244    JAV09840.1    GGMR01017712    MBY30331.1    GFXV01006803    MBW18608.1    GL440715    EFN65481.1    KQ414616    KOC68454.1    NEVH01002546    PNF42218.1    GGMS01013701    MBY82904.1    ABLF02034534    GECZ01031535    JAS38234.1    KZ288369    PBC26773.1    KQ435847    KOX71140.1    GECU01033753    JAS73953.1    GEBQ01013048    JAT26929.1    GBRD01003926    JAG61895.1    GBHO01006605    GBHO01006604    JAG36999.1    JAG37000.1    KL670487    KFW79084.1    KL447272    KFO71686.1    HACA01018103    CDW35464.1    LSYS01008511    OPJ68606.1    MUZQ01000022    OWK62767.1    KK510733    KFP63009.1    KL249296    KFV16877.1    KL224618    KFW61999.1    KK799393    KFQ27613.1    KL218151    KFP02723.1    KL225857    KFM04143.1    KK500601    KFP09375.1    KK684200    KFQ13888.1    KL409768    KFQ91924.1    ABQF01022070    ABQF01022071    KL873111    KGL97795.1    KK735002    KFR11847.1    KK933017    KFQ45909.1    KB549795    EMP30479.1    KK701179    KFQ27340.1    GDHC01015489    JAQ03140.1    GBHO01006603    JAG37001.1    QUSF01000011    RLW05216.1    KK454619    KFQ75611.1    KZ506141    PKU41258.1    KK827993    KFP74251.1    AGTO01000643    KK718721    KFO58223.1    LMAW01000570    KQL08864.1    HAEI01005542    SBR93765.1    NEVH01025130    PNF15972.1    KK399979    KFV59399.1    AWGT02000044    OXB80767.1    KL217272    KFV76004.1    HADX01000921    SBP23153.1    HAAF01010170    CCP81994.1    PNF15973.1    KL523247    KFO90336.1    KL891705    KGL78977.1    JH001439    EGW00424.1    KK852779    KDR16698.1    AK037287    AK081674    AK137206    BC151181    BC151182    BC157914    AK129447    MCFN01000199    OXB62777.1    AY364634    AABR07072041    KE673595    ERE77128.1    AEFK01081014    AEFK01081015    JH431327    HAEA01009565    SBQ38045.1   

Proteomes

UP000007151    UP000053268    UP000030742    UP000036403    UP000002358    UP000019118    + More
UP000053097    UP000007266    UP000007755    UP000078542    UP000078492    UP000075809    UP000005205    UP000245037    UP000008237    UP000078541    UP000078540    UP000000311    UP000053825    UP000235965    UP000005203    UP000192223    UP000007819    UP000242457    UP000053105    UP000053258    UP000053760    UP000190648    UP000197619    UP000054081    UP000054308    UP000053286    UP000053119    UP000053283    UP000007754    UP000053858    UP000053605    UP000031443    UP000276834    UP000016665    UP000052976    UP000051836    UP000248480    UP000198419    UP000053875    UP000053641    UP000001075    UP000027135    UP000000589    UP000264820    UP000198323    UP000261660    UP000002494    UP000030759    UP000005226    UP000007648    UP000265080   

PRIDE

G3I7L3    Q3UVK0    Q6UPR8    F1M6W2   

Pfam

PF04389   Peptidase_M28

Interpro

IPR007484   Peptidase_M28        + More
IPR020846   MFS_dom       

CDD

cd06174  MFS

ProteinModelPortal

A0A2H1VFV2   A0A212F2C4   A0A0N0P9G5   A0A0C9PTF3   U4UG35   A0A0J7N8Q2   + More
A0A0C9RLF9   K7IVE8   A0A1Y1MFR8   E9J751   N6TCR2   V5I8A6   A0A026WBF2   D6WUE4   F4W998   A0A151IAH4   A0A151J3X6   A0A151X8Z6   A0A158P124   A0A1L8DTQ3   A0A2P8XUX7   E2B4B7   A0A195F463   A0A195B525   A0A1L8DTY6   A0A2S2PLK7   A0A2H8TZN1   E2AM75   A0A0L7RC84   A0A2J7RN14   A0A087ZYD9   A0A2S2QYZ9   A0A1W4WC11   J9JNK1   A0A1B6EJY6   A0A2A3E4U7   A0A0M8ZU08   A0A1B6HGX1   A0A1B6LTH2   A0A0K8T9R5   A0A0A9YXT3   A0A093S894   A0A091FRS0   A0A0K2UB59   A0A1V4J8U0   A0A218V9N9   A0A091LXC2   A0A093CX59   A0A093QTD4   A0A091QKA7   A0A091I5H3   A0A087QSD9   A0A091IPN9   A0A091Q2Z9   A0A091ULW7   H0Z3K7   A0A0A0AXF3   A0A091W890   A0A091RUS3   M7B0C0   A0A091QIJ3   A0A146L905   A0A0A9YZF9   A0A3L8SN96   A0A091TIN8   A0A2I0U5B6   A0A091MHJ1   U3K7N8   A0A091EJV4   A0A0Q3PUG0   A0A1A8QIW3   A0A2J7PI20   A0A2Y9DFB7   A0A093FYF8   A0A226PN18   A0A093JAQ1   A0A1A7XYP6   U3I8J8   U6DHE9   A0A2J7PI21   A0A091H3C2   A0A099ZBA7   G3I7L3   A0A067R1N3   Q3UVK0   A0A3Q3DLX3   A0A226N5G8   A0A3Q3FWJ9   Q6UPR8   F1M6W2   A0A061IAA3   H2UKM2   G3VQE6   T1IR32   A0A3P8T428   A0A1A8DUM0  

PDB

5IB9     E-value=8.06049e-05,     Score=110

KEGG

101735998    no KO assigned | (RefSeq) endoplasmic reticulum metallopeptidase 1-like

GO

GO:0016021   GO:0006508   GO:0046872   GO:0001541   GO:0008237   GO:0005783   GO:0005789   GO:0016787  

Subcellular location

Endoplasmic reticulum membrane  

Length:

400

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

42.6430299999999

Exp number, first 60 AAs:

20.67129

Total prob of N-in:

0.92521

POSSIBLE N-term signal

sequence

inside

1  -  19

TMhelix

20  -  42

outside

43  -  359

TMhelix

360  -  382

inside

383  -  400

 

 

Pi

173.850917

Theta

158.187015

Tajima's D

0.537382

CLR

0.108453

CSRT

0.529773511324434

Interpretation

Uncertain