Gene

KWMTBOMO11231

Pre Gene Modal

BGIBMGA012609

Annotation

AAA_family_ATPase_[Bombyx_mori]

Location

Bomo_Chr19(+):1504505-1506026      View in EpiBrowser

Full name

Pachytene checkpoint protein 2 homolog      

Alternative Name

Thyroid hormone receptor interactor 13 homolog
Thyroid receptor-interacting protein 13 homolog

Location in the cell

Cytoplasmic   Reliability : 2.321

CDS

ATGAATTTAAAAAATTCATTACACGTCGAAGTCGCTCAAAAACGAGAAAGCCGGCTGTGTAAAGACCGTATTAAAGATCTCGTTCATTCACATTTAGCAAACTACGTTTGTTTAACTCCTGGTGCTAGTATCACTGGACCAGAACTTGAAGAAAATATAGAACTACAGGAGCACGTCCACTCTATAACATTCTGTGATGTTGATCACCATACAGAGGTGTCAGCTACTGCCGTGGACTTGATCTACCACGTTTACAAGCTAGATACGTTCGGAGTAGAGACTGATACCATGACCGATGCTTCAACGGGAGAAGAATTTGCAGCCGCAGACGTATGGTCTCTACCAGCTCAAGATTTTCACGGTCTCTGGGAGAACTTAGTGTATGATACGAAATTAAAAGAAGACACAGTTAGATTTGTGGAGACTGCACTAGACTTTGCTGATCGCGGTGTTGACCCACACATTGTGAGTTGTAATCGTGTTGTGTTGTTACACGGACCACCAGGGACAGGGAAAACGAGCCTGTGTCGCGCTCTGGCTCAGAAACTCGCCATCAGACTAGGTGACCGGTTCCCGCGAGCTAGACTAGTCGAAATAAATGCACATGGACTATTTTCAAAGTGGTTTGCTGAGAGTGGAAAGCTCGTCGCTAGATTATTTGAACGCGTCGTTGAGATTGTGTCCGATCGCCGGCTACTAGCAGTCGTGCTCGTAGATGAGGTAGAATCATTAGCGGCCGCAAGACGAGCTGCAATTGCCGGCCTCGAACCGAGCGACTCTATTCGCGCCGTGAACGCTCTTCTAACTCAGCTGGACCGATTAAGGCGATTTCCTAATGTTCTCGTTTTGACAACATCAAACGTAACAGGCGCGATTGATGTGGCTTTTGTGGACCGTGCTGATTTAAAACGGCTTGTGGGACCACCATCAGCCCGTGCCGCCTACCAAGTATTGAGTGGATGCTGTAGTGAGCTTATGGCACGAGGTGTAATAACACAACGGGAACGTGTGTTTTCACTGTGTGTGTTAGAGAGTGCAAGGTTTGCCGAGAGTGCAGGATCACGTGCAAGTGTGCGCCTGTGGGGATTAGCACAAGAGGCAGCAGCACGAGGTCTGAGTGGGAGGGCACTGCGTCGTTTGCCTGTTCTAGCCACATTACAGGGACGAGGTATGAAGGCACCAGACCTTCTTATATTTATTGAGTGGTTATATGCAGCGCTGCACCAATACCTTGAAGATGCAACACAACTAGACGATGAACACAATCAAAGACCCCCTCCTGTAGTAGTTACTAATGGACATTAA

Protein

MNLKNSLHVEVAQKRESRLCKDRIKDLVHSHLANYVCLTPGASITGPELEENIELQEHVHSITFCDVDHHTEVSATAVDLIYHVYKLDTFGVETDTMTDASTGEEFAAADVWSLPAQDFHGLWENLVYDTKLKEDTVRFVETALDFADRGVDPHIVSCNRVVLLHGPPGTGKTSLCRALAQKLAIRLGDRFPRARLVEINAHGLFSKWFAESGKLVARLFERVVEIVSDRRLLAVVLVDEVESLAAARRAAIAGLEPSDSIRAVNALLTQLDRLRRFPNVLVLTTSNVTGAIDVAFVDRADLKRLVGPPSARAAYQVLSGCCSELMARGVITQRERVFSLCVLESARFAESAGSRASVRLWGLAQEAAARGLSGRALRRLPVLATLQGRGMKAPDLLIFIEWLYAALHQYLEDATQLDDEHNQRPPPVVVTNGH

Description

Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways (By similarity).

Similarity

Belongs to the AAA ATPase family.
Belongs to the AAA ATPase family. PCH2 subfamily.

Keywords

ATP-binding   Complete proteome   Differentiation   Meiosis   Nucleotide-binding   Oogenesis   Reference proteome   Spermatogenesis  

Feature

chain  Pachytene checkpoint protein 2 homolog

Uniprot

Q1HQ67   A0A2H1VZ57   A0A212F2E4   A0A0N1IMS5   A0A2W1BWR8   A0A0N1PF42   + More
A0A0L7LPW0   A0A2A4K4Y8   S4PWY1   A0A2W1BRV3   A0A1S3H9M9   A0A1S3KC13   A0A154PAN0   A0A087ZSN4   A0A232F863   A0A154NWR4   A0A3S0ZV67   A0A067R3J4   A0A2C9JZN1   A0A1B1JCG4   E2AFA1   A0A2A3EGN8   A0A0P4VZI3   F4X3K7   A0A1X7VVD0   T2MCX8   A0A195CR81   W4YUD2   A0A0N8BUQ2   A7SZE7   A0A0P4Z9E7   E9ISK2   A0A0N8E6L9   V5SKQ2   A0A0P6GXB8   K7IVL2   A0A0P5TGM3   A0A0P5E272   A0A0P5DKC5   K7F5Z3   A0A0P5DID7   A0A0P5DKR1   A0A151X3Y5   A0A2P2IE83   A0A0P6G1C5   A0A195BLK6   A0A158NZZ7   A0A210PWC5   A0A3P8UUS9   A0A3R7LXK0   I3J4L3   A0A3P8NQX4   A0A3P9CAY3   A0A3Q3C6A0   E9HAQ4   A0A3S2PJI9   A0A3B4GGK6   A0A2T7NIM1   A0A176VP42   A0A2R6WJD5   A0A3Q3G4A5   Q6P4W8   H2LVI2   A0A3P9MAJ2   A0A3P9IGV3   A0A3P8SM53   A0A0T6B0C2   C3YFI7   A0A195E0Z6   A0A3Q1BVC1   A0A195F321   A0A0L8HHX9   A0A0P5KE15   A0A0P5Z049   A0A1B6BWW7   A0A3B3HZ39   A0A3Q1CVG0   E1C6Q1   A0A3Q3QNX5   G1MSN1   A0A146X5W8   A0A3Q1ITK4   A0A146X3J8   A0A0N8ECL1   A0A146QL98   A0A3Q4HHX0   A0A146X4U7   A0A091FK79   A0A093P581   A0A3B3CS67   A0A3B4TRA8   A0A3Q2PNU3   M4AHZ8   A0A3Q2Z1D3   A0A0K9PBR1   A0A3P8ZAL2   A0A146X3L1   Q6PH52   F1RBS4  

Pubmed

19121390    22118469    26354079    28756777    26227816    23622113    + More
28648823    24845553    15562597    18574105    20798317    21719571    24065732    17615350    21282665    20075255    17381049    21347285    28812685    24487278    25186727    21292972    17554307    18563158    15592404    20838655    29451363    23542700    26814964    25069045    23594743   

EMBL

BABH01035942    DQ443185    ABF51274.1    ODYU01005342    SOQ46087.1    AGBW02010753    + More
OWR47896.1    KQ459449    KPJ00915.1    KZ149965    PZC76193.1    KQ461184    KPJ07503.1    JTDY01000383    KOB77444.1    NWSH01000125    PCG79307.1    GAIX01005998    JAA86562.1    KZ149961    PZC76345.1    KQ434857    KZC08903.1    NNAY01000752    OXU26680.1    KQ434776    KZC04109.1    RQTK01000132    RUS86639.1    KK852780    KDR16657.1    KU359117    ANS11596.1    GL439086    EFN67887.1    KZ288266    PBC30171.1    GDRN01095977    GDRN01095972    JAI59429.1    GL888624    EGI58804.1    HAAD01003704    CDG69936.1    KQ977394    KYN03002.1    AAGJ04084967    GDIQ01143043    GDIP01103245    JAL08683.1    JAM00470.1    DS469963    EDO30919.1    GDIP01216090    JAJ07312.1    GL765434    EFZ16275.1    GDIQ01056716    JAN38021.1    KC904225    AHB51067.1    GDIP01206485    GDIQ01244158    GDIQ01110152    GDIP01044614    GDIQ01039981    JAJ16917.1    JAN54756.1    GDIP01127944    JAL75770.1    GDIP01153802    JAJ69600.1    GDIP01160997    JAJ62405.1    AGCU01019150    AGCU01019151    AGCU01019152    GDIP01155757    JAJ67645.1    GDIP01154852    JAJ68550.1    KQ982557    KYQ55091.1    IACF01006725    LAB72308.1    GDIQ01039979    LRGB01000384    JAN54758.1    KZS19458.1    KQ976440    KYM86570.1    ADTU01005178    NEDP02005445    OWF40790.1    QCYY01003017    ROT65916.1    AERX01033829    AERX01033830    GL732612    EFX71223.1    CM012452    RVE62606.1    PZQS01000012    PVD21002.1    LVLJ01003285    OAE22041.1    KZ772756    PTQ33975.1    BC063217    LJIG01016429    KRT80628.1    GG666509    EEN60950.1    KQ979955    KYN18549.1    KQ981856    KYN34577.1    KQ418094    KOF88863.1    GDIQ01211262    GDIQ01110151    JAK40463.1    GDIP01050910    JAM52805.1    GEDC01031764    JAS05534.1    AADN02027348    GCES01049641    JAR36682.1    GCES01049640    JAR36683.1    GDIP01059115    GDIQ01039980    JAM44600.1    JAN54757.1    GCES01129695    JAQ56627.1    GCES01049644    JAR36679.1    KK719167    KFO61755.1    KL225096    KFW67422.1    LFYR01000980    KMZ66411.1    GCES01049643    JAR36680.1    BC056713    CU463028   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000037510    UP000218220    + More
UP000085678    UP000076502    UP000005203    UP000215335    UP000271974    UP000027135    UP000076420    UP000000311    UP000242457    UP000007755    UP000007879    UP000078542    UP000007110    UP000001593    UP000002358    UP000007267    UP000075809    UP000076858    UP000078540    UP000005205    UP000242188    UP000265120    UP000283509    UP000005207    UP000265100    UP000265160    UP000264840    UP000000305    UP000261460    UP000245119    UP000264800    UP000008143    UP000001038    UP000265180    UP000265200    UP000265080    UP000001554    UP000078492    UP000257160    UP000078541    UP000053454    UP000000539    UP000261600    UP000001645    UP000265040    UP000261580    UP000052976    UP000054081    UP000261560    UP000261420    UP000265000    UP000002852    UP000264820    UP000036987    UP000265140    UP000000437   

PRIDE

Q1HQ67    E1C6Q1   

Pfam

PF00004   AAA

Interpro

IPR003593   AAA+_ATPase        + More
IPR001270   ClpA/B       
IPR003960   ATPase_AAA_CS       
IPR027417   P-loop_NTPase       
IPR003959   ATPase_AAA_core       

SUPFAM

SSF52540   SSF52540       

ProteinModelPortal

Q1HQ67   A0A2H1VZ57   A0A212F2E4   A0A0N1IMS5   A0A2W1BWR8   A0A0N1PF42   + More
A0A0L7LPW0   A0A2A4K4Y8   S4PWY1   A0A2W1BRV3   A0A1S3H9M9   A0A1S3KC13   A0A154PAN0   A0A087ZSN4   A0A232F863   A0A154NWR4   A0A3S0ZV67   A0A067R3J4   A0A2C9JZN1   A0A1B1JCG4   E2AFA1   A0A2A3EGN8   A0A0P4VZI3   F4X3K7   A0A1X7VVD0   T2MCX8   A0A195CR81   W4YUD2   A0A0N8BUQ2   A7SZE7   A0A0P4Z9E7   E9ISK2   A0A0N8E6L9   V5SKQ2   A0A0P6GXB8   K7IVL2   A0A0P5TGM3   A0A0P5E272   A0A0P5DKC5   K7F5Z3   A0A0P5DID7   A0A0P5DKR1   A0A151X3Y5   A0A2P2IE83   A0A0P6G1C5   A0A195BLK6   A0A158NZZ7   A0A210PWC5   A0A3P8UUS9   A0A3R7LXK0   I3J4L3   A0A3P8NQX4   A0A3P9CAY3   A0A3Q3C6A0   E9HAQ4   A0A3S2PJI9   A0A3B4GGK6   A0A2T7NIM1   A0A176VP42   A0A2R6WJD5   A0A3Q3G4A5   Q6P4W8   H2LVI2   A0A3P9MAJ2   A0A3P9IGV3   A0A3P8SM53   A0A0T6B0C2   C3YFI7   A0A195E0Z6   A0A3Q1BVC1   A0A195F321   A0A0L8HHX9   A0A0P5KE15   A0A0P5Z049   A0A1B6BWW7   A0A3B3HZ39   A0A3Q1CVG0   E1C6Q1   A0A3Q3QNX5   G1MSN1   A0A146X5W8   A0A3Q1ITK4   A0A146X3J8   A0A0N8ECL1   A0A146QL98   A0A3Q4HHX0   A0A146X4U7   A0A091FK79   A0A093P581   A0A3B3CS67   A0A3B4TRA8   A0A3Q2PNU3   M4AHZ8   A0A3Q2Z1D3   A0A0K9PBR1   A0A3P8ZAL2   A0A146X3L1   Q6PH52   F1RBS4  

PDB

6F0X     E-value=3.42799e-78,     Score=743

KEGG

732909    K22399 pachytene checkpoint protein 2 | (RefSeq) AAA family ATPase

GO

GO:0005524   GO:0016021   GO:0051598   GO:0007131   GO:0005694   GO:0001556   GO:0042802   GO:0007141   GO:0007144   GO:0006302   GO:0001673   GO:0007286   GO:0007094   GO:0007130   GO:0007283   GO:0048477   GO:0005549   GO:0007608   GO:0016020   GO:0005515   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

Length:

434

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.07197

Exp number, first 60 AAs:

0.01239

Total prob of N-in:

0.00634

outside

1  -  434

 

 

Pi

147.903532

Theta

143.278333

Tajima's D

0.168066

CLR

1.637382

CSRT

0.414829258537073

Interpretation

Uncertain