Gene

KWMTBOMO11224

Pre Gene Modal

BGIBMGA012608

Annotation

PREDICTED:_nose_resistant_to_fluoxetine_protein_6-like_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr19(+):1405296-1417350      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.901

CDS

ATGCCAGCGTTATTCAAATTTGACAATTACGAAGAATGCTTGAGCAAGCCAGAAGGGATATACTGTACTACCAAATTTGAAATTATAAAGATTACGCCAAACCCCGTTTATGATATGATAGTTGAATTTTCCAAGCACACCGTGAAACATTACAATCATTCTAAGCTTTTCTACGGTGTGTGCTTGTCTGATAATCGTAACCAAACAAATATTTCAACGTGGGACCTGAAACAGAGCGTTGAGGCCCGTCTCAACGAATCGTTTTGGTCCGAGCATCGCTTGAGAACAAAAATCACCGATATATCGTGTTCCAATGAGAAGGAAGATTATAAGTTGGATATCGGTGACGTAATTGTTGGCACCGCCTGTCTTATTTTAGTTCTACTGAACGTCGTTGCAAGTTTTTGTGATTTATACTTCGGTGATGAAAATAATAAAAGCCCGGAATGGTACCACTATTTTTCAATACGATGCAACTGGCGTAGGCTGATGGAGCCATTTGACGAGACCAACCCGCGGCTTCGTCCACTGAAATGTTTGAACGGTTTAAGGAGTGTATTAATGTGTTTGGTGATATTGATACACACGAGCGTCCCAGTCTTCGTGTGTAACAATAATCCTAGATATTTGGAGCAGTGGTTTGACAATATTTACTACCATCTACTGTTCAACGCTACCTTTATAATGCAGATTTTCATTGTAATATCGGGATTCCTGTTAATATACAACCAGCAAATATCTGATGAAAGTAATGAAATTAGCTGGAAAATTTTACCAAAACGGACTTTAGAGAGATGGTTGCGGCTTACACCGCCGTATGCCGTAATATTGGCGCTGACCGCGACTTGGTTCAGACATGTCGGTTCAGGACCATTCTGGCCTGAGGTCGCCGGGTCCGAAATACGTGATTGCAGAAGATATTGGTGGCAACATCTCTTGTACATCCACAACTACAGTAACGAATCAGACTGCACGATACAATCTTGGTACATAGCCGCTGATATGCAGCTGTTCATTTTCGGATTAATCATCTATCTGGCCTGCCGAACTCCGAGGTCTAGGAAGATAGTCCTTCCCACTTTTTTCTTTATAGGCATCGCCATAGTAGCCGCTCACACGTACTTAGAAAACTTGGATGGAACCGTCATTTGCACTCCTGAAGTCATTCGCAACCAAATCAGGATAGACCCGACGTTCTTAAAAGTCTACAGACGAAGTCACACTAATATACCCTGTTACATTCTGGGGATGGGTGCAGGATACCTGTTTTACTATTGGCAGAAGATTAACCTGAATTTGGATAAAATTAAGAAATATAAAATGCTCTGCTGGATGCTTGGTCCGCTGCCAGTAGTCCTGGGTTCTGGCATAATGGTCATGGCCTCGTATTTCTACATGGACGCGCCAAGGTCTTCAGTCATGTTGAGAACAATGTACGCTGCAACTGCGAAACCTGTTTTTGGATTACTGTTCACAGTACTTATATGCGCAATGATCATGAAACTTGAAAACGTCTTCCGTACAATATTCGAGTGGGATTGTTGGTCGATCGTGGCGCGTCTATCGTACTGCGCCTACAATATCCATGTGACCATTATTCGGTACACCGCATCACTGTCCACCGTTCCTTTCCAACAATCGATTATGGCTATGGTTCAGTACTACATTTTCATCCTGGTCGTCTCTTTGCTTCTCTCCATTCCGCTTTGGTTGCTGGTTGAAGAACCGATGAACCGAGTGTGGAAATTATATCTAAGATCTTCCTCTAAGACGACTCAGGTGCAGGAGAAAATTAAGCTGAAATAG

Protein

MPALFKFDNYEECLSKPEGIYCTTKFEIIKITPNPVYDMIVEFSKHTVKHYNHSKLFYGVCLSDNRNQTNISTWDLKQSVEARLNESFWSEHRLRTKITDISCSNEKEDYKLDIGDVIVGTACLILVLLNVVASFCDLYFGDENNKSPEWYHYFSIRCNWRRLMEPFDETNPRLRPLKCLNGLRSVLMCLVILIHTSVPVFVCNNNPRYLEQWFDNIYYHLLFNATFIMQIFIVISGFLLIYNQQISDESNEISWKILPKRTLERWLRLTPPYAVILALTATWFRHVGSGPFWPEVAGSEIRDCRRYWWQHLLYIHNYSNESDCTIQSWYIAADMQLFIFGLIIYLACRTPRSRKIVLPTFFFIGIAIVAAHTYLENLDGTVICTPEVIRNQIRIDPTFLKVYRRSHTNIPCYILGMGAGYLFYYWQKINLNLDKIKKYKMLCWMLGPLPVVLGSGIMVMASYFYMDAPRSSVMLRTMYAATAKPVFGLLFTVLICAMIMKLENVFRTIFEWDCWSIVARLSYCAYNIHVTIIRYTASLSTVPFQQSIMAMVQYYIFILVVSLLLSIPLWLLVEEPMNRVWKLYLRSSSKTTQVQEKIKLK

Catalytic Activity

S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.

Uniprot

A0A194QFD0   A0A2H1WAR4   A0A2W1BKH3   A0A2A4JGW2   A0A2W1BK62   A0A194QKZ1   + More
A0A212ETZ7   A0A2H1WAT5   A0A2A4JGF7   A0A212EGP9   A0A2H1WAT4   A0A194QEZ9   A0A3S2P8D1   A0A0N1I4J5   A0A2W1BKB8   A0A0L7L068   A0A0N1I9M0   A0A194QX14   A0A0N0PAP1   A0A0N1IBJ6   H9J531   A0A0N1ID86   A0A0N0P9S1   A0A2A4JF89   A0A1Y1KVX9   H9JU90   A0A2H1WCF8   A0A2H1WCA0   M4M6W5   A0A0L7L4N3   A0A2A4K959   A0A0N0PCP5   A0A2W1BKH9   A0A194QF68   A0A212FGA7   A0A1Y1M2Q0   A0A2W1BIR4   A0A182QFB6   B0WNX6   A0A2J7Q6G4   A7URR6   A7URR4   A0A2A4K429   A1Z6Q3   A7URR5   A0A212FM91   A7URR7   A0A1Y9J0V8   A0A194QVJ9   A0A2H1WLB9   A0A1Y9J0V5   A0A1I8MIA6   Q7PTG8   A0A034VZ12   A0A1Y9GKS0   A0A0K8VXE6   A0A182R1B6   A0A1Y9J0F0   A0A1Y9IRB4   A0A2A4JEH1   H9JW27   A0A0A1WJP0   A0A182FHE0   A0A182MV59   A0A182NJC1   A0A182R4J9   A0A182GNM9   B4QDR7   A0A1Y9IRE9   A0A182WLD5   Q16SA6   A0A0J9R828   A0A1W4V1V5   A0A194Q6D5   A0A182YEG1   A0A1W4VFG7   A0NBK6   A0A182I2D7   A0A182LZY6   A0A1Y1K4C2   Q16FE0   A0A1S4FSF3   A0A182KQ82   Q16FG3   A0A1A9WWJ5  

Pubmed

26354079    28756777    22118469    26227816    19121390    28004739    + More
23294019    12364791    14747013    17210077    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    25315136    25348373    25830018    26483478    17994087    17510324    22936249    25244985    20966253   

EMBL

KQ459053    KPJ04119.1    ODYU01007420    SOQ50171.1    KZ150085    PZC73777.1    + More
NWSH01001633    PCG70632.1    KZ150068    PZC74095.1    KPJ04116.1    AGBW02012502    OWR44975.1    SOQ50170.1    NWSH01001667    PCG70472.1    AGBW02015045    OWR40663.1    SOQ50173.1    KPJ04118.1    RSAL01000205    RVE44373.1    KQ459449    KPJ00879.1    PZC74094.1    JTDY01004025    KOB68696.1    KPJ00868.1    KQ461073    KPJ09500.1    KQ461184    KPJ07529.1    KPJ07525.1    BABH01038834    KPJ07535.1    KPJ00884.1    PCG70631.1    GEZM01074205    GEZM01074204    JAV64641.1    BABH01004270    BABH01004271    SOQ50174.1    ODYU01007576    SOQ50462.1    JX846987    AGG55004.1    JTDY01003022    KOB70291.1    NWSH01000045    PCG80260.1    KQ460635    KPJ13420.1    KZ149997    PZC75398.1    KPJ04127.1    AGBW02008687    OWR52781.1    GEZM01042633    JAV79751.1    KZ150097    PZC73595.1    AXCN02000449    DS232017    EDS31995.1    NEVH01017478    PNF24171.1    AAAB01008807    EDO64708.1    EDO64706.1    NWSH01000169    PCG78819.1    AE013599    AAF57404.4    EDO64707.1    AGBW02007654    OWR54851.1    EDO64709.1    KPJ09497.1    ODYU01009435    SOQ53859.1    EAA03947.5    GAKP01011630    JAC47322.1    APCN01000148    APCN01000149    GDHF01008758    JAI43556.1    AXCN02000448    PCG70475.1    BABH01025581    GBXI01015426    JAC98865.1    AXCM01001275    JXUM01076912    JXUM01076913    JXUM01076914    JXUM01076915    KQ562977    KXJ74719.1    CM000362    EDX05929.1    CH477678    EAT37346.1    CM002911    KMY91834.1    KQ459582    KPI98970.1    EAU77672.2    APCN01000146    AXCM01001276    AXCM01001277    GEZM01096350    JAV54960.1    CH478459    EAT32956.1    CH478446    EAT32978.1   

Proteomes

UP000053268    UP000218220    UP000007151    UP000283053    UP000037510    UP000053240    + More
UP000005204    UP000075886    UP000002320    UP000235965    UP000007062    UP000000803    UP000076407    UP000095301    UP000075840    UP000075903    UP000069272    UP000075883    UP000075884    UP000075900    UP000069940    UP000249989    UP000000304    UP000075920    UP000008820    UP000192221    UP000076408    UP000075882    UP000091820   

PRIDE

H9J531    H9JU90    A1Z6Q3    H9JW27   

Pfam

PF01757   Acyl_transf_3        + More
PF04488   Gly_transf_sug
PF02958   EcKinase
PF00632   HECT
PF00397   WW
PF00168   C2

Interpro

IPR002656   Acyl_transf_3        + More
IPR007577   GlycoTrfase_DXD_sugar-bd_CS       
IPR004119   EcKinase-like       
IPR011009   Kinase-like_dom_sf       
IPR015897   CHK_kinase-like       
IPR000569   HECT_dom       
IPR035983   Hect_E3_ubiquitin_ligase       
IPR035892   C2_domain_sf       
IPR036020   WW_dom_sf       
IPR001202   WW_dom       
IPR000008   C2_dom       

SUPFAM

SSF56112   SSF56112        + More
SSF56204   SSF56204       
SSF51045   SSF51045       

Gene 3D

2.60.40.150    

CDD

cd00201  WW
cd00078  HECTc

ProteinModelPortal

A0A194QFD0   A0A2H1WAR4   A0A2W1BKH3   A0A2A4JGW2   A0A2W1BK62   A0A194QKZ1   + More
A0A212ETZ7   A0A2H1WAT5   A0A2A4JGF7   A0A212EGP9   A0A2H1WAT4   A0A194QEZ9   A0A3S2P8D1   A0A0N1I4J5   A0A2W1BKB8   A0A0L7L068   A0A0N1I9M0   A0A194QX14   A0A0N0PAP1   A0A0N1IBJ6   H9J531   A0A0N1ID86   A0A0N0P9S1   A0A2A4JF89   A0A1Y1KVX9   H9JU90   A0A2H1WCF8   A0A2H1WCA0   M4M6W5   A0A0L7L4N3   A0A2A4K959   A0A0N0PCP5   A0A2W1BKH9   A0A194QF68   A0A212FGA7   A0A1Y1M2Q0   A0A2W1BIR4   A0A182QFB6   B0WNX6   A0A2J7Q6G4   A7URR6   A7URR4   A0A2A4K429   A1Z6Q3   A7URR5   A0A212FM91   A7URR7   A0A1Y9J0V8   A0A194QVJ9   A0A2H1WLB9   A0A1Y9J0V5   A0A1I8MIA6   Q7PTG8   A0A034VZ12   A0A1Y9GKS0   A0A0K8VXE6   A0A182R1B6   A0A1Y9J0F0   A0A1Y9IRB4   A0A2A4JEH1   H9JW27   A0A0A1WJP0   A0A182FHE0   A0A182MV59   A0A182NJC1   A0A182R4J9   A0A182GNM9   B4QDR7   A0A1Y9IRE9   A0A182WLD5   Q16SA6   A0A0J9R828   A0A1W4V1V5   A0A194Q6D5   A0A182YEG1   A0A1W4VFG7   A0NBK6   A0A182I2D7   A0A182LZY6   A0A1Y1K4C2   Q16FE0   A0A1S4FSF3   A0A182KQ82   Q16FG3   A0A1A9WWJ5  

KEGG

101735739    no KO assigned | (RefSeq) nose resistant to fluoxetine protein 6-like

GO

GO:0016021   GO:0016747   GO:0004842   GO:0005549   GO:0007608   GO:0016020   GO:0005515   GO:0006811   GO:0005622   GO:0006810   GO:0003824  

Length:

601

Number of predicted TMHs:

11

Exp number of AAs in TMHs:

231.19298

Exp number, first 60 AAs:

0.00108

Total prob of N-in:

0.03290

outside

1  -  113

TMhelix

114  -  136

inside

137  -  179

TMhelix

180  -  202

outside

203  -  216

TMhelix

217  -  239

inside

240  -  265

TMhelix

266  -  284

outside

285  -  324

TMhelix

325  -  347

inside

348  -  355

TMhelix

356  -  375

outside

376  -  406

TMhelix

407  -  426

inside

427  -  441

TMhelix

442  -  464

outside

465  -  478

TMhelix

479  -  501

inside

502  -  513

TMhelix

514  -  536

outside

537  -  550

TMhelix

551  -  573

inside

574  -  601

 

 

Pi

187.715462

Theta

169.279439

Tajima's D

-0.794671

CLR

0.470882

CSRT

0.180890955452227

Interpretation

Uncertain